Expression of cyclooxygenase-2 in pterygium and effects of selective cyclooxygenase-2 inhibitor on human pterygium fibroblasts

Chinese Journal of Ophthalmology

Volumn 43, Issue 10, 2007, Pages 881-884

  Gao, Yuan ^a   Zhang, Ming Chang ^a   Peng, Yun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Fibroblast growth factor; Fibroblasts; Prostaglandin endoperoxide synthase; Pterygium; Sulfonamides

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; FIBROBLAST GROWTH FACTOR 2; PTGS2 PROTEIN, HUMAN;

ADULT; ARTICLE; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECT; FEMALE; FIBROBLAST; HUMAN; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PTERYGIUM;

ADULT; CELL PROLIFERATION; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; FEMALE; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; HUMANS; MALE; MIDDLE AGED; PTERYGIUM;

EID: 78049505123     PISSN: 04124081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hill J C, Maske R. Pathogenesis of pterygium. Eye, 1989, 3: 218-226.
2. 2002, 20: 552.
3. Mitchell JA, Larkin S, Williams TJ. Cyclooxygenase-2: regulation and relevance ininflammation. Biochem Pharmacol, 1995, 50: 1535-1542.
4. Morris CD, Armstrong GR, Bigley G, et al. Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. Am J Gastroenterol, 2001, 96: 990-996.
5. Ghosh AK, Hirasawa N, Niki H, et al. Cyclooxygenase-2 mediated angiogenesis in carrageen in induced granulation tissue in rats. Pharmacol Exp Ther, 2000, 295: 802-809.
6. Sellers RS, Silverman L, Khan KN. Cyclooxygenase-2 expression in the cornea of dogs with keratitis. Vet Pathol, 2004, 41; 116-121.
7. Tuo J, Tuaillon N, Shen D, et al. Endotoxin-induced uveitis in cyclo oxygenase-2-deficient mice. Invest Ophthalmol Vis Sci, 2004, 45: 2306-2313.
8. Marshall JL, Stanfield KM, Silverman L, et al. Enhanced expression of cyclooxygenase-2 in glaucomatous dog eyes. Vet Ophthalmol, 2004, 7: 59-62.
9. 2004, 22: 964-968.
10. Ayalasomayajula SP, Kompella UB. Celecoxib, a selective cyclo oxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in astreptozotocin-induced diabetic rat model. Eur J Pharmacol, 2003, 458: 283-289.
11. Wilkinson-Berka JL, Alousis NS, Kelly DJ, et al. COX-2 inhibition and retinal angiogenesis in a mouse model of retinopathy of prematurity. Invest Ophthalmol Vis Sci, 2003, 44: 974-979.
12. Zhang F, Warskulat U, Wettstein M, et al. Hyperosmolarity stimulates prpstaglandin synthesis and cyclooxygenase-2 expression inactivated rat liver macrophages. Biochem J, 1995, 312: 135-143.
13. Powers MR, Qu Z, O'Brien B, et al. Immune-localization of bFGF in pterygia: association with mast cells. Cornea, 1997, 16: 545-549.
14. Hernandez GL, Volpert OV, Iniguez MA, et al. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclo-sporin A: roles of the nuclear factor of activated T cells and cyclo-oxygenase-2. Exp Med, 2001, 193: 607-620.
15. Master JL, Leahy KM, Koki AT, et al. Antiangiogenic and antitumor activitie of cyclooxygenase-2 inhibitors. Cancer Res, 2000, 60; 1306-1311.
16. Daniel TO, Liu H, Morrow JD, et al. Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. Cancer Res, 1999, 59: 4574-4577.
17. 2004, 14: 473-476.