-
1
-
-
33645470674
-
Neuroleptic effects of chlorpromazine in therapeutics of neuropsychiatry
-
Delay J, Denicker P. Neuroleptic effects of chlorpromazine in therapeutics of neuropsychiatry. J Clin Exp Psychopathol. 1955;16:104-112.
-
(1955)
J Clin Exp Psychopathol
, vol.16
, pp. 104-112
-
-
Delay, J.1
Denicker, P.2
-
2
-
-
0028293406
-
Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone
-
Janssen PA, Awouters FH. Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone. Arzneimittelforschung. 1994;44:269-277.
-
(1994)
Arzneimittelforschung
, vol.44
, pp. 269-277
-
-
Janssen, P.A.1
Awouters, F.H.2
-
3
-
-
0017651563
-
Does dopamine play a role in schizophrenia?
-
Carlsson A. Does dopamine play a role in schizophrenia? Psychol Med. 1977;7:583-597.
-
(1977)
Psychol Med
, vol.7
, pp. 583-597
-
-
Carlsson, A.1
-
4
-
-
0017255979
-
Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
-
Creese I, Burt DR, Snyder SH. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science. 1976;192:481-483.
-
(1976)
Science
, vol.192
, pp. 481-483
-
-
Creese, I.1
Burt, D.R.2
Snyder, S.H.3
-
5
-
-
0017068246
-
Antipsychotic drug doses and neuroleptic/dopamine receptors
-
Seeman P, Lee T, Chau-Wong M, Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature. 1976; 261:717-719.
-
(1976)
Nature
, vol.261
, pp. 717-719
-
-
Seeman, P.1
Lee, T.2
Chau-Wong, M.3
Wong, K.4
-
6
-
-
33847685647
-
Illuminating the molecular basis for some antipsychotic drug-induced metabolic burden
-
Meltzer HY. Illuminating the molecular basis for some antipsychotic drug-induced metabolic burden. Proc Natl Acad Sci U S A. 2007;104:3019-3020.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3019-3020
-
-
Meltzer, H.Y.1
-
7
-
-
0000439046
-
Prevalence of alcohol, drug and mental disorders among the homeless: one more time
-
Lehman AF, Cordray DS. Prevalence of alcohol, drug and mental disorders among the homeless: one more time. Contemporary Drug Problems. 1993;20:355-384.
-
(1993)
Contemporary Drug Problems
, vol.20
, pp. 355-384
-
-
Lehman, A.F.1
Cordray, D.S.2
-
8
-
-
59249100318
-
Penrose's law revisited: the relationship between mental institution beds, prison population and crime rate
-
Hartvig P, Kjelsberg E. Penrose's law revisited: the relationship between mental institution beds, prison population and crime rate. Nord J Psychiatry. 2009;63:51-56.
-
(2009)
Nord J Psychiatry
, vol.63
, pp. 51-56
-
-
Hartvig, P.1
Kjelsberg, E.2
-
9
-
-
26644472427
-
The economic burden of schizophrenia in the United States in 2002
-
Wu EQ, Birnbaum HG, Shi L, et al. The economic burden of schizophrenia in the United States in 2002. J Clin Psychiatry. 2005;66:1122-1129.
-
(2005)
J Clin Psychiatry
, vol.66
, pp. 1122-1129
-
-
Wu, E.Q.1
Birnbaum, H.G.2
Shi, L.3
-
10
-
-
0038653525
-
A meta-analysis of the efficacy of secondgeneration antipsychotics
-
Davis JM, Chen N, Glick ID. A meta-analysis of the efficacy of secondgeneration antipsychotics. Arch Gen Psychiatry. 2003;60:553-564.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 553-564
-
-
Davis, J.M.1
Chen, N.2
Glick, I.D.3
-
11
-
-
25144456112
-
Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) investigators: Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
Lieberman JA, Stroup TS, McEvoy JP, et al. Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) investigators: Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005;353:1209-1223.
-
(2005)
N Engl J Med
, vol.353
, pp. 1209-1223
-
-
Lieberman, J.A.1
Stroup, T.S.2
McEvoy, J.P.3
-
12
-
-
33749321169
-
Randomized controlled trial of the effect on quality of life of secondvs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
-
Jones PB, Barnes TR, Davies L, et al. Randomized controlled trial of the effect on quality of life of secondvs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Arch Gen Psychiatry. 2006;63:1079-1087.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 1079-1087
-
-
Jones, P.B.1
Barnes, T.R.2
Davies, L.3
-
13
-
-
33749333592
-
Comparative effectiveness of antipsychotic drugs: a commentary on: Cost Utility Of The Latest Antipsychotic Drugs In Schizophrenia Study (CUtLASS 1) and Clinical Antipsychotic Trials Of Intervention Effectiveness (CATIE)
-
Lieberman JA. Comparative effectiveness of antipsychotic drugs: a commentary on: Cost Utility Of The Latest Antipsychotic Drugs In Schizophrenia Study (CUtLASS 1) and Clinical Antipsychotic Trials Of Intervention Effectiveness (CATIE). Arch Gen Psychiatry. 2006;63:1069-1072.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 1069-1072
-
-
Lieberman, J.A.1
-
14
-
-
0026746727
-
Relationship between symptoms rated with the Positive and Negative Syndrome Scale and brain measures in schizophrenia
-
d'Amato T, Rochet T, Dalery J, et al. Relationship between symptoms rated with the Positive and Negative Syndrome Scale and brain measures in schizophrenia. Psychiatry Res. 1992;44:55-62.
-
(1992)
Psychiatry Res
, vol.44
, pp. 55-62
-
-
d'Amato, T.1
Rochet, T.2
Dalery, J.3
-
15
-
-
1142285269
-
The deficit syndrome in schizophrenia: implications for the treatment of negative symptoms
-
Arango C, Buchanan RW, Kirkpatrick B, Carpenter WT. The deficit syndrome in schizophrenia: implications for the treatment of negative symptoms. Eur Psychiatry. 2004;19:21-26.
-
(2004)
Eur Psychiatry
, vol.19
, pp. 21-26
-
-
Arango, C.1
Buchanan, R.W.2
Kirkpatrick, B.3
Carpenter, W.T.4
-
16
-
-
65849281129
-
Neurocognition in first-episode schizophrenia: a meta-analytic review
-
Mesholam-Gately RI, Giuliano AJ, Goff KP, Faraone SV, Seidman LJ. Neurocognition in first-episode schizophrenia: a meta-analytic review. Neuropsychology. 2009;23:315-336.
-
(2009)
Neuropsychology
, vol.23
, pp. 315-336
-
-
Mesholam-Gately, R.I.1
Giuliano, A.J.2
Goff, K.P.3
Faraone, S.V.4
Seidman, L.J.5
-
17
-
-
0031903740
-
Neurocognitive deficit in schizophrenia: a quantitative review of the evidence
-
Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998;12:426-445.
-
(1998)
Neuropsychology
, vol.12
, pp. 426-445
-
-
Heinrichs, R.W.1
Zakzanis, K.K.2
-
18
-
-
32244437440
-
Hippocampal and amygdala volumes according to psychosis stage and diagnosis: a magnetic resonance imaging study of chronic schizophrenia, first-episode psychosis, and ultrahigh-risk individuals
-
Velakoulis D, Wood SJ, Wong MT, et al. Hippocampal and amygdala volumes according to psychosis stage and diagnosis: a magnetic resonance imaging study of chronic schizophrenia, first-episode psychosis, and ultrahigh-risk individuals. Arch Gen Psychiatry. 2006;63:139-149.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 139-149
-
-
Velakoulis, D.1
Wood, S.J.2
Wong, M.T.3
-
19
-
-
34248145966
-
Progressive and interrelated functional and structural evidence of post-onset brain reduction in schizophrenia
-
Salisbury DF, Kuroki N, Kasai K, Shenton ME, McCarley RW. Progressive and interrelated functional and structural evidence of post-onset brain reduction in schizophrenia. Arch Gen Psychiatry. 2007;64:521-529.
-
(2007)
Arch Gen Psychiatry
, vol.64
, pp. 521-529
-
-
Salisbury, D.F.1
Kuroki, N.2
Kasai, K.3
Shenton, M.E.4
McCarley, R.W.5
-
20
-
-
77955328701
-
Convergent approaches for defining functional imaging endophenotypes in schizophrenia
-
Pearlson GD, Calhoun VD. Convergent approaches for defining functional imaging endophenotypes in schizophrenia. Front Hum Neurosci. 2009;3:37.
-
(2009)
Front Hum Neurosci
, vol.3
, pp. 37
-
-
Pearlson, G.D.1
Calhoun, V.D.2
-
21
-
-
62349119965
-
Recent diffusion tensor imaging findings in early stages of schizophrenia
-
Kyriakopoulos M, Frangou S. Recent diffusion tensor imaging findings in early stages of schizophrenia. Curr Opin Psychiatry. 2009:22:168-176.
-
Curr Opin Psychiatry
, vol.22
, pp. 2009-176
-
-
Kyriakopoulos, M.1
Frangou, S.2
-
23
-
-
73949124536
-
Sensory processing in schizophrenia: neither simple nor intact
-
Javitt DC. Sensory processing in schizophrenia: neither simple nor intact. Schizophr Bull. 2009;35:1059-1064.
-
(2009)
Schizophr Bull
, vol.35
, pp. 1059-1064
-
-
Javitt, D.C.1
-
25
-
-
70449240781
-
Study of a new schizophrenomimetic drug; sernyl
-
Luby ED, Cohen BD, Rosenbaum G, Gottlieb JS, Kelley R. Study of a new schizophrenomimetic drug; sernyl. AMA Arch Neurol Psychiatry 1959;81:363-369.
-
(1959)
AMA Arch Neurol Psychiatry
, vol.81
, pp. 363-369
-
-
Luby, E.D.1
Cohen, B.D.2
Rosenbaum, G.3
Gottlieb, J.S.4
Kelley, R.5
-
26
-
-
0025952455
-
Recent advances in the phencyclidine model of schizophrenia
-
Javitt DC, Zukin, SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry. 1991;148:1301-1308.
-
(1991)
Am J Psychiatry
, vol.148
, pp. 1301-1308
-
-
Javitt, D.C.1
Zukin, S.R.2
-
27
-
-
0020629581
-
The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate
-
Anis NA, Berry SC, Burton NR, Lodge D. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br J Pharmacol. 1983;79:565-575.
-
(1983)
Br J Pharmacol
, vol.79
, pp. 565-575
-
-
Anis, N.A.1
Berry, S.C.2
Burton, N.R.3
Lodge, D.4
-
28
-
-
0028323167
-
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
-
Krystal JH, Karper LP, Seibyl JP, et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 1994;51:199-214.
-
(1994)
Arch Gen Psychiatry
, vol.51
, pp. 199-214
-
-
Krystal, J.H.1
Karper, L.P.2
Seibyl, J.P.3
-
29
-
-
0033080733
-
Ketamineinduced NMDA receptor hypofunction as a model of memory impairment and psychosis
-
Newcomer JW, Farber NB, Jevtovic-Todorovic V, et al. Ketamineinduced NMDA receptor hypofunction as a model of memory impairment and psychosis. Neuropsychopharmacology. 1999;20:106-118.
-
(1999)
Neuropsychopharmacology
, vol.20
, pp. 106-118
-
-
Newcomer, J.W.1
Farber, N.B.2
Jevtovic-Todorovic, V.3
-
30
-
-
0033663587
-
Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: implications for models of cognitive deficits in schizophrenia
-
Umbricht D, Schmid L, Koller R, Vollenweider FX, Hell D, Javitt DC. Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: implications for models of cognitive deficits in schizophrenia. Arch Gen Psychiatry. 2000;57:1139-1147.
-
(2000)
Arch Gen Psychiatry
, vol.57
, pp. 1139-1147
-
-
Umbricht, D.1
Schmid, L.2
Koller, R.3
Vollenweider, F.X.4
Hell, D.5
Javitt, D.C.6
-
31
-
-
0032210874
-
Does ketamine-mediated N-methyl-D-aspartate receptor antagonism cause schizophrenia-like oculomotor abnormalities?
-
Radant AD, Bowdle TA, Cowley DS, Kharasch ED, Roy-Byrne PP. Does ketamine-mediated N-methyl-D-aspartate receptor antagonism cause schizophrenia-like oculomotor abnormalities? Neuropsychopharmacology 1998;19:434-444.
-
(1998)
Neuropsychopharmacology
, vol.19
, pp. 434-444
-
-
Radant, A.D.1
Bowdle, T.A.2
Cowley, D.S.3
Kharasch, E.D.4
Roy-Byrne, P.P.5
-
32
-
-
0034307054
-
Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia
-
Kegeles LS, Abi-Dargham A, Zea-Ponce Y, et al. Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia. Biol Psychiatry. 2000;48:627-640.
-
(2000)
Biol Psychiatry
, vol.48
, pp. 627-640
-
-
Kegeles, L.S.1
Abi-Dargham, A.2
Zea-Ponce, Y.3
-
33
-
-
0034851624
-
Effects of ketamine in normal and schizophrenic volunteers
-
Lahti AC, Weiler MA, TamaraMichaelidis BA, Parwani A, Tamminga CA. Effects of ketamine in normal and schizophrenic volunteers. Neuropsychopharmacology. 2001;25:455-467.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 455-467
-
-
Lahti, A.C.1
Weiler, M.A.2
TamaraMichaelidis, B.A.3
Parwani, A.4
Tamminga, C.A.5
-
34
-
-
0018352931
-
An analysis of factors influencing measurements of dopamine, noradrenaline, glutamate decarboxylase and choline acetylase in human post-mortem brain tissue
-
Spokes EG. An analysis of factors influencing measurements of dopamine, noradrenaline, glutamate decarboxylase and choline acetylase in human post-mortem brain tissue. Brain. 1979;102:333-346.
-
(1979)
Brain
, vol.102
, pp. 333-346
-
-
Spokes, E.G.1
-
36
-
-
0032778735
-
Evidence for altered trisynaptic circuitry in schizophrenic hippocampus
-
Benes FM. Evidence for altered trisynaptic circuitry in schizophrenic hippocampus. Biol Psychiatry. 1999;46:589-599.
-
(1999)
Biol Psychiatry
, vol.46
, pp. 589-599
-
-
Benes, F.M.1
-
37
-
-
43349105701
-
Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia
-
Hashimoto T, Bazmi HH, Mirnics K, Wu Q, Sampson AR, Lewis DA. Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry. 2008;165:479489.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 479489
-
-
Hashimoto, T.1
Bazmi, H.H.2
Mirnics, K.3
Wu, Q.4
Sampson, A.R.5
Lewis, D.A.6
-
38
-
-
0036784474
-
Reciprocal alterations in preand post-synaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia
-
Volk DW, Pierri JN, Fritschy JM, Auh S, Sampson AR, Lewis DA. Reciprocal alterations in preand post-synaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia. Cereb Cortex. 2002;12:1063-1070.
-
(2002)
Cereb Cortex
, vol.12
, pp. 1063-1070
-
-
Volk, D.W.1
Pierri, J.N.2
Fritschy, J.M.3
Auh, S.4
Sampson, A.R.5
Lewis, D.A.6
-
39
-
-
0033985644
-
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
-
Glantz LA, Lewis DA. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry. 2000;57:65-73.
-
(2000)
Arch Gen Psychiatry
, vol.57
, pp. 65-73
-
-
Glantz, L.A.1
Lewis, D.A.2
-
40
-
-
57849160321
-
Reduced dendritic spine density in auditory cortex of subjects with schizophrenia
-
Sweet RA, Henteleff RA, Zhang W, Sampson AR, Lewis DA. Reduced dendritic spine density in auditory cortex of subjects with schizophrenia. Neuropsychopharmacology. 2009;34:374-389.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 374-389
-
-
Sweet, R.A.1
Henteleff, R.A.2
Zhang, W.3
Sampson, A.R.4
Lewis, D.A.5
-
41
-
-
36848999339
-
Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase
-
Behrens MM, Ali SS, Dao DN, Lucero J, Shekhtman G, Quick KL, Dugan LL. Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase. Science. 2007;318:1645-1647.
-
(2007)
Science
, vol.318
, pp. 1645-1647
-
-
Behrens, M.M.1
Ali, S.S.2
Dao, D.N.3
Lucero, J.4
Shekhtman, G.5
Quick, K.L.6
Dugan, L.L.7
-
42
-
-
55249115993
-
Prolonged exposure to NMDAR antagonist suppresses inhibitory synaptic transmission in prefrontal cortex
-
Zhang Y, Behrens MM, Lisman JE. Prolonged exposure to NMDAR antagonist suppresses inhibitory synaptic transmission in prefrontal cortex. J Neurophysiol. 2008;100:959-965.
-
(2008)
J Neurophysiol
, vol.100
, pp. 959-965
-
-
Zhang, Y.1
Behrens, M.M.2
Lisman, J.E.3
-
43
-
-
42749095376
-
Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
-
Lisman JE, Coyle JT, Green RW, et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 2008;31:234-242.
-
(2008)
Trends Neurosci
, vol.31
, pp. 234-242
-
-
Lisman, J.E.1
Coyle, J.T.2
Green, R.W.3
-
44
-
-
37149006927
-
Regulation of spine morphology and spine density by NMDA receptor signaling in vivo
-
Ultanir SK, Kim JE, Hall BJ, Deerinck T, Ellisman M, Ghosh A. Regulation of spine morphology and spine density by NMDA receptor signaling in vivo. Proc Natl Acad Sci U S A. 2007;104:19553-19558.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19553-19558
-
-
Ultanir, S.K.1
Kim, J.E.2
Hall, B.J.3
Deerinck, T.4
Ellisman, M.5
Ghosh, A.6
-
45
-
-
67649329655
-
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior
-
Basu AC, Tsai GE, Ma CL, et al. Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior. Mol Psychiatry. 2009;14:719-727.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 719-727
-
-
Basu, A.C.1
Tsai, G.E.2
Ma, C.L.3
-
46
-
-
78649726089
-
Altered cortical dendritic morphology in serine racemase knockout mice, a genetic model of NMDA receptor hypofunction
-
Abs. No. 443.16
-
Balu D, Basu AC, Coyle JT. Altered cortical dendritic morphology in serine racemase knockout mice, a genetic model of NMDA receptor hypofunction. Soc Neurosci. 2009. Abs. No. 443.16.
-
(2009)
Soc Neurosci
-
-
Balu, D.1
Basu, A.C.2
Coyle, J.T.3
-
47
-
-
46249104490
-
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database
-
Allen NC, Bagade S, McQueen MB, et al. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet. 2008;40:827-834.
-
(2008)
Nat Genet
, vol.40
, pp. 827-834
-
-
Allen, N.C.1
Bagade, S.2
McQueen, M.B.3
-
48
-
-
33745912772
-
Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia
-
Hahn CG, Wang HY, Cho DS, et al. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med. 2006;12:824-828.
-
(2006)
Nat Med
, vol.12
, pp. 824-828
-
-
Hahn, C.G.1
Wang, H.Y.2
Cho, D.S.3
-
49
-
-
70350052966
-
Dysbindin modulates prefrontal cortical glutamatergic circuits and working memory function in mice
-
Jentsch JD, Trantham-Davidson H, Jairl C, Tinsley M, Cannon TD, Lavin A. Dysbindin modulates prefrontal cortical glutamatergic circuits and working memory function in mice. Neuropsychopharmacology. 2009;34:2601-2608.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 2601-2608
-
-
Jentsch, J.D.1
Trantham-Davidson, H.2
Jairl, C.3
Tinsley, M.4
Cannon, T.D.5
Lavin, A.6
-
50
-
-
59149090292
-
Hyperactivity and hyperconnectivity of the default network in schizophrenia and in firstdegree relatives of persons with schizophrenia
-
Whitfield-Gabrieli S, Thermenos HW, Milanovic S, et al. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in firstdegree relatives of persons with schizophrenia. Proc Natl Acad Sci U S A. 2009;106:1279-1284.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1279-1284
-
-
Whitfield-Gabrieli, S.1
Thermenos, H.W.2
Milanovic, S.3
-
51
-
-
78049295974
-
Dopamine system dysregulation by the ventral subiculum as the common pathophysiological basis for schizophrenia psychosis, psychostimulant abuse, and stress
-
(Epub ahead of print)
-
Grace AA. Dopamine system dysregulation by the ventral subiculum as the common pathophysiological basis for schizophrenia psychosis, psychostimulant abuse, and stress. Neurotox Res. 2010 (Epub ahead of print).
-
(2010)
Neurotox Res
-
-
Grace, A.A.1
-
52
-
-
0027905017
-
Modulation of neuronal migration by NMDA receptors
-
Komuro H, Rakic P. Modulation of neuronal migration by NMDA receptors. Science. 1993;260:95-97.
-
(1993)
Science
, vol.260
, pp. 95-97
-
-
Komuro, H.1
Rakic, P.2
-
53
-
-
0027394523
-
Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development
-
Akbarian S, Bunney WE Jr, Potkin SG, Wigal SB, Hagman JO, Sandman CA, Jones EG. Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development. Arch Gen Psychiatry. 1993;50:169-177.
-
(1993)
Arch Gen Psychiatry
, vol.50
, pp. 169-177
-
-
Akbarian, S.1
Bunney W.E., Jr.2
Potkin, S.G.3
Wigal, S.B.4
Hagman, J.O.5
Sandman, C.A.6
Jones, E.G.7
-
54
-
-
72049091251
-
Neuronal signaling pathways: genetic insights into the pathophysiology of major mental illness
-
Margolis RL, Ross CA. Neuronal signaling pathways: genetic insights into the pathophysiology of major mental illness. Neuropsychopharmacology. 2010;35:350-351.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 350-351
-
-
Margolis, R.L.1
Ross, C.A.2
-
55
-
-
62849120806
-
Network analysis of positional candidate genes of schizophrenia highlights myelin-related pathways
-
Rietkerk T, Boks MP, Sommer IE, de Jong S, Kahn RS, Ophoff RA. Network analysis of positional candidate genes of schizophrenia highlights myelin-related pathways. Mol Psychiatry. 2009;14:353-355.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 353-355
-
-
Rietkerk, T.1
Boks, M.P.2
Sommer, I.E.3
de Jong, S.4
Kahn, R.S.5
Ophoff, R.A.6
-
56
-
-
32544449944
-
Splice variants of the NR1 subunit differentially induce NMDA receptor-dependent gene expression
-
Bradley J, Carter SR, Rao VR, Wang J, Finkbeiner S. Splice variants of the NR1 subunit differentially induce NMDA receptor-dependent gene expression. J Neurosci. 2006;26:1065-1076.
-
(2006)
J Neurosci
, vol.26
, pp. 1065-1076
-
-
Bradley, J.1
Carter, S.R.2
Rao, V.R.3
Wang, J.4
Finkbeiner, S.5
-
57
-
-
0034845802
-
NMDA receptor pharmacology: Perspectives from molecular biology
-
Lynch DR, Guttmann RP. NMDA receptor pharmacology: Perspectives from molecular biology. Curr. Drug Targets. 2001;2:215-231.
-
(2001)
Curr. Drug Targets.
, vol.2
, pp. 215-231
-
-
Lynch, D.R.1
Guttmann, R.P.2
-
58
-
-
0032415129
-
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses
-
Berger AJ, Dieudonne S, Ascher P. Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses. J Neurophysiol. 1998;80:3336-3340.
-
(1998)
J Neurophysiol
, vol.80
, pp. 3336-3340
-
-
Berger, A.J.1
Dieudonne, S.2
Ascher, P.3
-
59
-
-
0023820777
-
Cooperative modulation of [3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines
-
Ransom RW, Stec NL. Cooperative modulation of [3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines. J Neurochem 1988;51:830-836.
-
(1988)
J Neurochem
, vol.51
, pp. 830-836
-
-
Ransom, R.W.1
Stec, N.L.2
-
60
-
-
0023273862
-
The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain
-
Foster AC, Wong EH. The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain. Br J Pharmacol. 1987;91:403-409.
-
(1987)
Br J Pharmacol
, vol.91
, pp. 403-409
-
-
Foster, A.C.1
Wong, E.H.2
-
61
-
-
0010748929
-
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist
-
Wong EH, Kemp JA, Priestley T, Knight AR, Woodruff GN, Iversen LL. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A. 1986;83:7104-7108.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 7104-7108
-
-
Wong, E.H.1
Kemp, J.A.2
Priestley, T.3
Knight, A.R.4
Woodruff, G.N.5
Iversen, L.L.6
-
62
-
-
1242296773
-
Identification and analysis of plasticity-induced late-response genes
-
Hong SJ, Li H, Becker KG, Dawson VL, Dawson TM. Identification and analysis of plasticity-induced late-response genes. Proc Natl Acad Sci U S A. 2004;100:2145-2150.
-
(2004)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2145-2150
-
-
Hong, S.J.1
Li, H.2
Becker, K.G.3
Dawson, V.L.4
Dawson, T.M.5
-
63
-
-
2342637165
-
Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
-
Liu L, Wong TP, Pozza MF, et al. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 2004;304:1021-1024.
-
(2004)
Science
, vol.304
, pp. 1021-1024
-
-
Liu, L.1
Wong, T.P.2
Pozza, M.F.3
-
64
-
-
33749074397
-
Glutamate and schizophrenia: beyond the dopamine hypothesis
-
Coyle JT. Glutamate and schizophrenia: beyond the dopamine hypothesis. Cell Mol Neurobiol. 2006;26:365-384.
-
(2006)
Cell Mol Neurobiol
, vol.26
, pp. 365-384
-
-
Coyle, J.T.1
-
65
-
-
0023091647
-
Glycine potentiates the NMDA response in cultured mouse brain neurons
-
Johnson JW, Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987;325:529-531.
-
(1987)
Nature
, vol.325
, pp. 529-531
-
-
Johnson, J.W.1
Ascher, P.2
-
66
-
-
0023754192
-
Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
-
Kleckner NW, Dingledine R. Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science. 1988;241:835-837.
-
(1988)
Science
, vol.241
, pp. 835-837
-
-
Kleckner, N.W.1
Dingledine, R.2
-
67
-
-
0024564769
-
Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices
-
Thomson AM, Walker VE, Flynn DM. Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices. Nature. 1989;338:422-424.
-
(1989)
Nature
, vol.338
, pp. 422-424
-
-
Thomson, A.M.1
Walker, V.E.2
Flynn, D.M.3
-
69
-
-
0037977113
-
Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the Nmethyl-D-aspartate receptor hypofunction hypothesis of schizophrenia
-
Hashimoto K, Fukushima T, Shimizu E, et al. Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the Nmethyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry. 2003;60:572-576.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 572-576
-
-
Hashimoto, K.1
Fukushima, T.2
Shimizu, E.3
-
70
-
-
33846640657
-
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia
-
Bendikov I, Nadri C, Amar S, Panizzutti R, De Miranda J, Wolosker H, Agam G. A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophr Res. 2007;90:41-51.
-
(2007)
Schizophr Res
, vol.90
, pp. 41-51
-
-
Bendikov, I.1
Nadri, C.2
Amar, S.3
Panizzutti, R.4
De Miranda, J.5
Wolosker, H.6
Agam, G.7
-
71
-
-
0035477818
-
Increased cortical kynurenate content in schizophrenia
-
Schwarcz R, Rassoulpour A, Wu HQ, Medoff D, Tamminga CA, Roberts RC. Increased cortical kynurenate content in schizophrenia. Biol Psychiatry. 2001;50:521-530.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 521-530
-
-
Schwarcz, R.1
Rassoulpour, A.2
Wu, H.Q.3
Medoff, D.4
Tamminga, C.A.5
Roberts, R.C.6
-
72
-
-
28244440276
-
Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia
-
Nilsson LK, Linderholm KR, Engberg G, et al. Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia. Schizophr Res. 2005;15;80:315-322.
-
(2005)
Schizophr Res
, vol.15
, Issue.80
, pp. 315-322
-
-
Nilsson, L.K.1
Linderholm, K.R.2
Engberg, G.3
-
73
-
-
0029020761
-
Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration
-
Matsui T, Sekiguchi M, Hashimoto A, Tomita U, Nishikawa T, Wada, K. Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration. J Neurochem. 1995;65:454-458.
-
(1995)
J Neurochem
, vol.65
, pp. 454-458
-
-
Matsui, T.1
Sekiguchi, M.2
Hashimoto, A.3
Tomita, U.4
Nishikawa, T.5
Wada, K.6
-
74
-
-
0025141342
-
D-cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed in Xenopus oocytes
-
158-160
-
Watson GB, Bolanowski MA, Baganoff MP, Deppeler CL, Lanthorn TH. D-cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed in Xenopus oocytes. Brain Res. 1990;26;510:158-160.
-
(1990)
Brain Res
, vol.26
, pp. 510
-
-
Watson, G.B.1
Bolanowski, M.A.2
Baganoff, M.P.3
Deppeler, C.L.4
Lanthorn, T.H.5
-
75
-
-
77949447469
-
Strategies to enhance N-methyl-D-aspartate receptormediated neurotransmission in schizophrenia, a critical review and metaanalysis
-
Tsai GE, Lin PY. Strategies to enhance N-methyl-D-aspartate receptormediated neurotransmission in schizophrenia, a critical review and metaanalysis. Curr Pharm Des. 2010;16:522-537.
-
(2010)
Curr Pharm Des
, vol.16
, pp. 522-537
-
-
Tsai, G.E.1
Lin, P.Y.2
-
76
-
-
35748969317
-
The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments
-
Buchanan RW, Javitt DC, Marder SR, et al. The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments. Am J Psychiatry. 2007;164:1593-1602.
-
(2007)
Am J Psychiatry
, vol.164
, pp. 1593-1602
-
-
Buchanan, R.W.1
Javitt, D.C.2
Marder, S.R.3
-
77
-
-
0032925438
-
Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia
-
Heresco-Levy, U, Javitt D C, Ermilov M, Mordel C, Silipo G, Lichtenstein M. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry. 1999;56:29-36.
-
(1999)
Arch Gen Psychiatry
, vol.56
, pp. 29-36
-
-
Heresco-Levy, U.1
Javitt, D.C.2
Ermilov, M.3
Mordel, C.4
Silipo, G.5
Lichtenstein, M.6
-
78
-
-
0035218449
-
Adjunctive high-dose glycine in the treatment of schizophrenia
-
Javitt DC, Silipo G, Cienfuegos A, Shelley AM, Bark N, Park M et al. Adjunctive high-dose glycine in the treatment of schizophrenia. Int J Neuropsychopharmacol. 2001;4:385-391.
-
(2001)
Int J Neuropsychopharmacol
, vol.4
, pp. 385-391
-
-
Javitt, D.C.1
Silipo, G.2
Cienfuegos, A.3
Shelley, A.M.4
Bark, N.5
Park, M.6
-
79
-
-
0029116094
-
Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia
-
Goff DC, Tsai G, Manoach DS, Coyle JT. Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia. Am J Psychiatry. 1995;152:1213-1215.
-
(1995)
Am J Psychiatry
, vol.152
, pp. 1213-1215
-
-
Goff, D.C.1
Tsai, G.2
Manoach, D.S.3
Coyle, J.T.4
-
80
-
-
0028246912
-
Acute but not chronic activation of the NMDA-coupled glycine receptor with Dcycloserine facilitates learning and retention
-
Quartermain D, Mower J, Rafferty MF, Herting RL, Lanthorn TH. Acute but not chronic activation of the NMDA-coupled glycine receptor with Dcycloserine facilitates learning and retention. Eur J Pharmacol. 1994;257:712.
-
(1994)
Eur J Pharmacol
, vol.257
, pp. 712
-
-
Quartermain, D.1
Mower, J.2
Rafferty, M.F.3
Herting, R.L.4
Lanthorn, T.H.5
-
81
-
-
0030006443
-
The NMDA antagonist MK-801 blocks the extinction of Pavlovian fear conditioning
-
Baker JD, Azorlosa JL. The NMDA antagonist MK-801 blocks the extinction of Pavlovian fear conditioning. Behav Neurosci. 1996;110:618-620.
-
(1996)
Behav Neurosci
, vol.110
, pp. 618620
-
-
Baker, J.D.1
Azorlosa, J.L.2
-
82
-
-
0037088911
-
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of Dcycloserine as assessed with fear-potentiated startle in rats
-
Walker DL, Ressler KJ, Lu KT, Davis M. Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of Dcycloserine as assessed with fear-potentiated startle in rats. J Neurosci. 2002;22:2343-2351.
-
(2002)
J Neurosci
, vol.22
, pp. 2343-2351
-
-
Walker, D.L.1
Ressler, K.J.2
Lu, K.T.3
Davis, M.4
-
83
-
-
71349083402
-
D-cycloserine facilitates extinction of naloxone-induced conditioned place aversion in morphine-dependent rats
-
Myers KM, Carlezon WA Jr. D-cycloserine facilitates extinction of naloxone-induced conditioned place aversion in morphine-dependent rats. Biol Psychiatry. 2010;67:85-87.
-
(2010)
Biol Psychiatry
, vol.67
, pp. 85-87
-
-
Myers, K.M.1
Carlezon W.A., Jr.2
-
84
-
-
4644355629
-
Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear
-
Ressler KJ, Rothbaum BO, Tannenbaum L, et al. Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry. 2004;61:1136-1144.
-
(2004)
Arch Gen Psychiatry
, vol.61
, pp. 1136-1144
-
-
Ressler, K.J.1
Rothbaum, B.O.2
Tannenbaum, L.3
-
85
-
-
44349151445
-
A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy
-
Norberg MM, Krystal JH, Tolin DF. A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy. Biol Psychiatry. 2008;63:1118-1126.
-
(2008)
Biol Psychiatry
, vol.63
, pp. 1118-1126
-
-
Norberg, M.M.1
Krystal, J.H.2
Tolin, D.F.3
-
86
-
-
0015015914
-
Uptake of radiolabeled essential amino acids by brain following arterial injection
-
Oldendorf WH. Uptake of radiolabeled essential amino acids by brain following arterial injection. Proc Soc Exp Biol Med. 1971;136:385-386.
-
(1971)
Proc Soc Exp Biol Med
, vol.136
, pp. 385-386
-
-
Oldendorf, W.H.1
-
87
-
-
3042757433
-
Effect of systemic administration of D-serine on the levels of Dand L-serine in several brain areas and periphery of rat
-
Hashimoto A, Chiba S. Effect of systemic administration of D-serine on the levels of Dand L-serine in several brain areas and periphery of rat. Eur J Pharmacol. 2004;495:153-158.
-
(2004)
Eur J Pharmacol
, vol.495
, pp. 153-158
-
-
Hashimoto, A.1
Chiba, S.2
-
88
-
-
0037401685
-
Differential effects of atypical and typical antipsychotic drugs on N-methyl-D-aspartateand electrically evoked responses in the pryramidal cells of the rat medial prefrontal cortex
-
Ninan I, Jardemark KE, Wang RY. Differential effects of atypical and typical antipsychotic drugs on N-methyl-D-aspartateand electrically evoked responses in the pryramidal cells of the rat medial prefrontal cortex. Synapse. 2003;48:66-79.
-
(2003)
Synapse
, vol.48
, pp. 66-79
-
-
Ninan, I.1
Jardemark, K.E.2
Wang, R.Y.3
-
89
-
-
15944428993
-
Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action
-
Javitt DC, Duncan L, Balla A, Sershen, H. Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action. Mol Psychiatry. 2005;10:275-287.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 275-287
-
-
Javitt, D.C.1
Duncan, L.2
Balla, A.3
Sershen, H.4
-
90
-
-
0026714534
-
Involvement of D-amino acid oxidase in elimination of Dserine in mouse brain
-
Nagata Y. Involvement of D-amino acid oxidase in elimination of Dserine in mouse brain. Experientia. 1992;48:753-755.
-
(1992)
Experientia
, vol.48
, pp. 753-755
-
-
Nagata, Y.1
-
91
-
-
0023445118
-
Localization of D-amino acid oxidase in Bergmann glial cells and astrocytes of rat cerebellum
-
Horiike K, Tojo H, Arai R, Yamano T, Nozaki M, Maeda T. Localization of D-amino acid oxidase in Bergmann glial cells and astrocytes of rat cerebellum. Brain Res Bull. 1987;19:587-596.
-
(1987)
Brain Res. Bull.
, vol.19
, pp. 587-596
-
-
Horiike, K.1
Tojo, H.2
Arai, R.3
Yamano, T.4
Nozaki, M.5
Maeda, T.6
-
92
-
-
75549091955
-
The neurobiology of Damino acid oxidase and its involvement in schizophrenia
-
Verrall L, Burnet PW, Betts JF, Harrison PJ. The neurobiology of Damino acid oxidase and its involvement in schizophrenia. Mol Psychiatry. 2010;15:122-137.
-
(2010)
Mol Psychiatry
, vol.15
, pp. 122-137
-
-
Verrall, L.1
Burnet, P.W.2
Betts, J.F.3
Harrison, P.J.4
-
93
-
-
33745689721
-
G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis
-
Detera-Wadleigh SD, McMahon FJ. G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis. Biol Psychiatry. 2006;60:106-114.
-
(2006)
Biol Psychiatry
, vol.60
, pp. 106-114
-
-
Detera-Wadleigh, S.D.1
McMahon, F.J.2
-
94
-
-
36849031756
-
Allelic association of G72/ G30 with schizophrenia and bipolar disorder: a comprehensive meta-analysis
-
Shi J, Badner JA, Gershon ES, Liu C. Allelic association of G72/ G30 with schizophrenia and bipolar disorder: a comprehensive meta-analysis. Schizophr Res. 2008;98:89-97.
-
(2008)
Schizophr Res
, vol.98
, pp. 89-97
-
-
Shi, J.1
Badner, J.A.2
Gershon, E.S.3
Liu, C.4
-
95
-
-
33746813128
-
Preliminary evidence for a link between schizophrenia and NMDA-glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1)
-
Kapoor R, Lim KS, Cheng A, Garrick T, Kapoor V. Preliminary evidence for a link between schizophrenia and NMDA-glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1). Brain Res. 2006;1106:205-210.
-
(2006)
Brain Res
, vol.1106
, pp. 205-210
-
-
Kapoor, R.1
Lim, K.S.2
Cheng, A.3
Garrick, T.4
Kapoor, V.5
-
96
-
-
43049108742
-
Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia
-
Madeira C, Freitas ME, Vargas-Lopes C, Wolosker H, Panizzutti R. Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia. Schizophr Res. 2008;101:76-83.
-
(2008)
Schizophr Res
, vol.101
, pp. 76-83
-
-
Madeira, C.1
Freitas, M.E.2
Vargas-Lopes, C.3
Wolosker, H.4
Panizzutti, R.5
-
97
-
-
45549094476
-
D-amino acid oxidase activity and expression are increased in schizophrenia
-
Burnet PW, Eastwood SL, Bristow GC, Godlewska BR, Sikka P, Walker M, Harrison PJ. D-amino acid oxidase activity and expression are increased in schizophrenia. Mol Psychiatry. 2008;3:658-660.
-
(2008)
Mol Psychiatry
, vol.3
, pp. 658-660
-
-
Burnet, P.W.1
Eastwood, S.L.2
Bristow, G.C.3
Godlewska, B.R.4
Sikka, P.5
Walker, M.6
Harrison, P.J.7
-
98
-
-
0037108758
-
Genetic and physiological data implicating the new human gene G72 and the gene for Damino acid oxidase in schizophrenia
-
Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H. et al. Genetic and physiological data implicating the new human gene G72 and the gene for Damino acid oxidase in schizophrenia. Proc Natl Acad Sci U S A. 2002;99:13675-13680.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13675-13680
-
-
Chumakov, I.1
Blumenfeld, M.2
Guerassimenko, O.3
Cavarec, L.4
Palicio, M.5
Abderrahim, H.6
-
99
-
-
38149040091
-
In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties
-
Adage T, Trillat AC, Quattropani A, et al. In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties. Eur Neuropsychopharmacol. 2008;18:200-214.
-
(2008)
Eur Neuropsychopharmacol
, vol.18
, pp. 200-214
-
-
Adage, T.1
Trillat, A.C.2
Quattropani, A.3
-
100
-
-
67349116852
-
Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine
-
Hashimoto K, Fujita Y, Horio M, et al. Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine. Biol Psychiatry. 2009;65:1103-1106.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 1103-1106
-
-
Hashimoto, K.1
Fujita, Y.2
Horio, M.3
-
101
-
-
62449161854
-
The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine
-
Smith SM, Uslaner JM, Yao L, et al. The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine. J Pharmacol Exp Ther. 2009;328:921-930.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 921-930
-
-
Smith, S.M.1
Uslaner, J.M.2
Yao, L.3
-
102
-
-
33645506167
-
Polymorphism in the 5'-promoter region of serine racemase gene in schizophrenia
-
Goltsov AY, Loseva JG, Andreeva TV, et al. Polymorphism in the 5'-promoter region of serine racemase gene in schizophrenia. Mol Psychiatry. 2006;11:325-326.
-
(2006)
Mol Psychiatry
, vol.11
, pp. 325-326
-
-
Goltsov, A.Y.1
Loseva, J.G.2
Andreeva, T.V.3
-
103
-
-
34247596490
-
A genetic variant of the serine racemase gene is associated with schizophrenia
-
Morita Y, Ujike H, Tanaka Y, Otani K, et al. A genetic variant of the serine racemase gene is associated with schizophrenia. Biol Psychiatry. 2007;61:1200-1203.
-
(2007)
Biol Psychiatry
, vol.61
, pp. 1200-1203
-
-
Morita, Y.1
Ujike, H.2
Tanaka, Y.3
Otani, K.4
-
104
-
-
68749087296
-
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model
-
Labrie V, Fukumura R, Rastogi A, et al. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet. 2009;18:3227-3243.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3227-3243
-
-
Labrie, V.1
Fukumura, R.2
Rastogi, A.3
-
105
-
-
0033539510
-
Serine racemase: A glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission
-
Wolosker H, Blackshaw S, Snyder SH. Serine racemase: A glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proc Natl Acad Sci U S A. 1999;96:13409-13414.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13409-13414
-
-
Wolosker, H.1
Blackshaw, S.2
Snyder, S.H.3
-
106
-
-
33744900653
-
Neuronderived D-serine release provides a novel means to activate N-methyl-Daspartate receptors
-
Kartvelishvily E, Shleper M, Balan L, Dumin E, Wolosker H. Neuronderived D-serine release provides a novel means to activate N-methyl-Daspartate receptors. J Biol Chem. 2006;281:14151-14162.
-
(2006)
J Biol Chem
, vol.281
, pp. 14151-14162
-
-
Kartvelishvily, E.1
Shleper, M.2
Balan, L.3
Dumin, E.4
Wolosker, H.5
-
107
-
-
53149109731
-
Serine racemase is predominantly localized in neurons in mouse brain
-
641-654
-
Miya K, Inoue R, Takata Y, et al. Serine racemase is predominantly localized in neurons in mouse brain. J Comp Neurol. 2008;20;510:641-654.
-
(2008)
J Comp Neurol
, vol.20
, pp. 510
-
-
Miya, K.1
Inoue, R.2
Takata, Y.3
-
108
-
-
68749087296
-
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model
-
Labrie V, Fukumura R, Rastogi A, Fick LJ, Wang W, Boutros PC, Kennedy JL, Semeralul MO, Lee FH, Baker GB, Belsham DD, Barger SW, Gondo Y, Wong AH, Roder JC. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet. 2009;18:3227-3243.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3227-3243
-
-
Labrie, V.1
Fukumura, R.2
Rastogi, A.3
Fick, L.J.4
Wang, W.5
Boutros, P.C.6
Kennedy, J.L.7
Semeralul, M.O.8
Lee, F.H.9
Baker, G.B.10
Belsham, D.D.11
Barger, S.W.12
Gondo, Y.13
Wong, A.H.14
Roder, J.C.15
-
109
-
-
34047261852
-
Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS
-
Rutter AR, Fradley RL, Garrett EM, et al. Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS. Eur J Neurosci. 2007;25:1757-1766.
-
(2007)
Eur J Neurosci
, vol.25
, pp. 1757-1766
-
-
Rutter, A.R.1
Fradley, R.L.2
Garrett, E.M.3
-
110
-
-
1542640509
-
Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain
-
Helboe L, Egebjerg J, Møller M, Thomsen C. Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain. Eur J Neurosci. 2003;18:2227-2238.
-
(2003)
Eur J Neurosci
, vol.18
, pp. 2227-2238
-
-
Helboe, L.1
Egebjerg, J.2
Møller, M.3
Thomsen, C.4
-
111
-
-
12144289325
-
High affinity Dand L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices
-
Matsuo H, Kanai Y, Tokunaga M, et al. High affinity Dand L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices. Neurosci Lett. 2004;358:123-126.
-
(2004)
Neurosci Lett
, vol.358
, pp. 123-126
-
-
Matsuo, H.1
Kanai, Y.2
Tokunaga, M.3
-
112
-
-
56049092225
-
Allosteric modulation of NMDA receptor via elevation of brain glycine and D-serine: the therapeutic potentials for schizophrenia
-
Yang CR, Svensson KA. Allosteric modulation of NMDA receptor via elevation of brain glycine and D-serine: the therapeutic potentials for schizophrenia. Pharmacol Ther. 2008;120:317-332.
-
(2008)
Pharmacol Ther
, vol.120
, pp. 317-332
-
-
Yang, C.R.1
Svensson, K.A.2
-
113
-
-
23644450359
-
Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice
-
Xie X, Dumas T, Tang L, et al. Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice. Brain Res. 2005;1052:212-221.
-
(2005)
Brain Res
, vol.1052
, pp. 212-221
-
-
Xie, X.1
Dumas, T.2
Tang, L.3
-
114
-
-
0026695974
-
Cloning, expression, and localization of a rat brain high-affinity glycine transporter
-
Guastella J, Brecha N, Weigmann C, Lester HA, Davidson N. Cloning, expression, and localization of a rat brain high-affinity glycine transporter. Proc Natl Acad Sci U S A. 1992;89:7189-7193.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 7189-7193
-
-
Guastella, J.1
Brecha, N.2
Weigmann, C.3
Lester, H.A.4
Davidson, N.5
-
115
-
-
0029014595
-
Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS
-
Zafra F, Gomeza J, Olivares L, Aragón C, Giménez C. Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS. Eur J Neurosci. 1995;7:1342-1352.
-
(1995)
Eur J Neurosci
, vol.7
, pp. 1342-1352
-
-
Zafra, F.1
Gomeza, J.2
Olivares, L.3
Aragón, C.4
Giménez, C.5
-
116
-
-
0037320805
-
Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo
-
Chen L, Muhlhauser M, Yang CR. Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo. J Neurophysiol 2003;89:691-703.
-
(2003)
J Neurophysiol
, vol.89
, pp. 691-703
-
-
Chen, L.1
Muhlhauser, M.2
Yang, C.R.3
-
117
-
-
0041920952
-
The glycine transporter type 1 inhibitor N-[3-(4_-fluorophenyl)-3-(4_phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior
-
Kinney GG, Sur C, Burno M, et al. The glycine transporter type 1 inhibitor N-[3-(4_-fluorophenyl)-3-(4_phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior. J Neurosci. 2003;23:7586-7591.
-
(2003)
J Neurosci
, vol.23
, pp. 7586-7591
-
-
Kinney, G.G.1
Sur, C.2
Burno, M.3
-
118
-
-
33748675922
-
Progress in the preparation and testing of glycine transporter type-1 (GlyT1) inhibitors
-
Lindsley CW, Wolkenberg SE, Kinney GG. Progress in the preparation and testing of glycine transporter type-1 (GlyT1) inhibitors. Curr Top Med Chem. 2006;6:1883-1896.
-
(2006)
Curr Top Med Chem
, vol.6
, pp. 1883-1896
-
-
Lindsley, C.W.1
Wolkenberg, S.E.2
Kinney, G.G.3
-
119
-
-
14044258729
-
Metabotropic glutamate receptors as novel targets for anxiety and stress disorders
-
Swanson C, Bures M, Johnson M, Linden A, Monn J, Schoepp D. Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat Rev Drug Discov. 2005;4:131-144.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 131-144
-
-
Swanson, C.1
Bures, M.2
Johnson, M.3
Linden, A.4
Monn, J.5
Schoepp, D.6
-
120
-
-
34347241277
-
Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs
-
Palucha A, Pilc A. Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs. Pharm Ther. 2007;115:116-147.
-
(2007)
Pharm Ther
, vol.115
, pp. 116-147
-
-
Palucha, A.1
Pilc, A.2
-
121
-
-
67651083577
-
The glutamate homeostasis hypothesis of addiction
-
Kalivas PW. The glutamate homeostasis hypothesis of addiction. Nat Rev Neurosci. 2009;10:561-572.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 561-572
-
-
Kalivas, P.W.1
-
122
-
-
58149119377
-
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia
-
Conn PJ, Lindsley CW, Jones CK. Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia. Trends Pharmacol Sci. 2009;30:25-31.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 25-31
-
-
Conn, P.J.1
Lindsley, C.W.2
Jones, C.K.3
-
123
-
-
0030995878
-
Pharmacology and functions of metabotropic glutamate receptors
-
Conn PJ, Pin J. Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol. 1997;37: 205-237.
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 205-237
-
-
Conn, P.J.1
Pin, J.2
-
124
-
-
0031036195
-
Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors
-
Scanziani M, Salin PA, Vogt KE, Malenka RC, Nicoll RA. Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors. Nature. 1997;385:630-634.
-
(1997)
Nature
, vol.385
, pp. 630-634
-
-
Scanziani, M.1
Salin, P.A.2
Vogt, K.E.3
Malenka, R.C.4
Nicoll, R.A.5
-
125
-
-
0033981186
-
Physiological antagonism between 5-hydroxytryptamine 2A and group II metabotropic glutamate receptors in prefrontal corotex
-
Marek GJ, Wright RA, Schoepp DD, Monn JA, Aghajanian GK. Physiological antagonism between 5-hydroxytryptamine 2A and group II metabotropic glutamate receptors in prefrontal corotex. J Pharmacol Exp Ther. 2000;292:76-87.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 76-87
-
-
Marek, G.J.1
Wright, R.A.2
Schoepp, D.D.3
Monn, J.A.4
Aghajanian, G.K.5
-
126
-
-
0036118255
-
Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus
-
Dietrich D, Kral T, Clusmann H, Friedl M, Schramm J. Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus. Neuropharmacology. 2002;42:297-305.
-
(2002)
Neuropharmacology
, vol.42
, pp. 297-305
-
-
Dietrich, D.1
Kral, T.2
Clusmann, H.3
Friedl, M.4
Schramm, J.5
-
127
-
-
0032575715
-
Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
-
Moghaddam B, Adams B. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science. 1998;281:1349-1352.
-
(1998)
Science
, vol.281
, pp. 1349-1352
-
-
Moghaddam, B.1
Adams, B.2
-
128
-
-
0030900732
-
Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
-
Moghaddam B, Adams B, Verma A, Daly D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci. 1997;17: 2921-2927.
-
(1997)
J Neurosci
, vol.17
, pp. 2921-2927
-
-
Moghaddam, B.1
Adams, B.2
Verma, A.3
Daly, D.4
-
130
-
-
33749645423
-
Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations
-
Lewis DA, Moghaddam B. Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations. Arch Neurol. 2006;63:1372-1376.
-
(2006)
Arch Neurol
, vol.63
, pp. 1372-1376
-
-
Lewis, D.A.1
Moghaddam, B.2
-
131
-
-
42749095376
-
Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
-
Lisman JE, Coyle JT, Green RW, et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 2008;31:234-242
-
(2008)
Trends Neurosci
, vol.31
, pp. 234-242
-
-
Lisman, J.E.1
Coyle, J.T.2
Green, R.W.3
-
132
-
-
0032834028
-
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
-
Schoepp DD, Jane DE, Monn JA. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology. 1999;38:1431-1476.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1431-1476
-
-
Schoepp, D.D.1
Jane, D.E.2
Monn, J.A.3
-
133
-
-
0032848507
-
The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats
-
Cartmell J, Monn JA, Schoepp DD. The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats. J Pharmacol Exp Ther. 1999;291:161-170.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 161-170
-
-
Cartmell, J.1
Monn, J.A.2
Schoepp, D.D.3
-
134
-
-
0033844601
-
Regulation of neurotransmitter release by metabotropic glutamate receptors
-
Cartmell J, Schoepp DD. Regulation of neurotransmitter release by metabotropic glutamate receptors. J Neurochem. 2000;75:889-907.
-
(2000)
J Neurochem
, vol.75
, pp. 889-907
-
-
Cartmell, J.1
Schoepp, D.D.2
-
135
-
-
27744597869
-
A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity
-
Galici R, Echemendia NG, Rodriguez AL, Conn PJ. A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity. J Pharmacol Exp Ther. 2005;315:1181-1187.
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 1181-1187
-
-
Galici, R.1
Echemendia, N.G.2
Rodriguez, A.L.3
Conn, P.J.4
-
136
-
-
33745227414
-
Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychoticand anxiolytic-like effects in mice
-
Galici R, Jones CK, Hemstapat K, Nong Y, Echemendia NG, Williams LC, de Paulis T, Conn PJ. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychoticand anxiolytic-like effects in mice. J Pharmacol Exp Ther. 2006;318:173-185.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 173-185
-
-
Galici, R.1
Jones, C.K.2
Hemstapat, K.3
Nong, Y.4
Echemendia, N.G.5
Williams, L.C.6
de Paulis, T.7
Conn, P.J.8
-
137
-
-
27744446102
-
Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands
-
Rorick-Kehn LM, Hart JC, McKinzie DL. Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands. Psychopharmacology (Berl). 2005;183: 226-240.
-
(2005)
Psychopharmacology (Berl)
, vol.183
, pp. 226-240
-
-
Rorick-Kehn, L.M.1
Hart, J.C.2
McKinzie, D.L.3
-
138
-
-
17744369682
-
Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: reversal by the mGLU(2/3) receptor agonist LY379268
-
Greco B, Invernizzi RW, Carli M. Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: reversal by the mGLU(2/3) receptor agonist LY379268. Psychopharmacology (Berl). 2005;179:68-76.
-
(2005)
Psychopharmacology (Berl)
, vol.179
, pp. 68-76
-
-
Greco, B.1
Invernizzi, R.W.2
Carli, M.3
-
139
-
-
0032527894
-
Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine
-
Adams B, Moghaddam B. Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine. J Neurosci. 1998;15;18:5545-5554.
-
(1998)
J Neurosci
, vol.15
, Issue.18
, pp. 5545-5554
-
-
Adams, B.1
Moghaddam, B.2
-
140
-
-
34547198448
-
A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis
-
Benneyworth MA, Xiang Z, Smith RL, Garcia EE, Conn PJ, Sanders-Bush E. A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. Mol Pharmacol. 2007;72:477-484.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 477-484
-
-
Benneyworth, M.A.1
Xiang, Z.2
Smith, R.L.3
Garcia, E.E.4
Conn, P.J.5
Sanders-Bush, E.6
-
141
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial
-
Patil ST, Zhang L, Martenyi F, et al. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med. 2007;13:1102-1107.
-
(2007)
Nat Med
, vol.13
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
-
142
-
-
20944439080
-
Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects
-
Krystal JH, Abi-Saab W, Perry E, et al. Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects. Psychopharmacology (Berl). 2005;179:303-309.
-
(2005)
Psychopharmacology (Berl)
, vol.179
, pp. 303-309
-
-
Krystal, J.H.1
Abi-Saab, W.2
Perry, E.3
-
143
-
-
15544385061
-
Activation of metabotropic glutamate 2/3 receptors reverses the effects of NMDA receptor hypofunction on prefrontal cortex unit activity in awake rats
-
Homayoun H, Jackson ME, Moghaddam B. Activation of metabotropic glutamate 2/3 receptors reverses the effects of NMDA receptor hypofunction on prefrontal cortex unit activity in awake rats. J Neurophysiol. 2005;93:1989-2001.
-
(2005)
J Neurophysiol
, vol.93
, pp. 1989-2001
-
-
Homayoun, H.1
Jackson, M.E.2
Moghaddam, B.3
-
144
-
-
0030821474
-
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus
-
Shigemoto R, Kinoshita A, Wada E, et al. Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci. 1997;17: 7503-7522.
-
(1997)
J Neurosci
, vol.17
, pp. 7503-7522
-
-
Shigemoto, R.1
Kinoshita, A.2
Wada, E.3
-
145
-
-
0035960059
-
Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to preand postsynaptic sites
-
Tamaru Y, Nomura S, Mizuno N, Shigemoto R Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to preand postsynaptic sites. Neuroscience. 2001;106:481-503.
-
(2001)
Neuroscience
, vol.106
, pp. 481-503
-
-
Tamaru, Y.1
Nomura, S.2
Mizuno, N.3
Shigemoto, R.4
-
146
-
-
34547686245
-
The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection
-
Corti C, Battaglia G, Molinaro G, et al. The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection. J Neurosci. 2007;27:8297-8308.
-
(2007)
J Neurosci
, vol.27
, pp. 8297-8308
-
-
Corti, C.1
Battaglia, G.2
Molinaro, G.3
-
147
-
-
0034717225
-
Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice
-
Spooren WP, Gasparini F, van der Putten H, Koller M, Nakanishi S, Kuhn R. Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice. Eur J Pharmacol. 2000;397:R1-R2.
-
(2000)
Eur J Pharmacol
, vol.397
-
-
Spooren, W.P.1
Gasparini, F.2
van der Putten, H.3
Koller, M.4
Nakanishi, S.5
Kuhn, R.6
-
148
-
-
58149119377
-
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia
-
Conn PJ, Lindsley CW, Jones CK. Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia. Trends Pharmacol Sci. 2009;30:25-31.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 25-31
-
-
Conn, P.J.1
Lindsley, C.W.2
Jones, C.K.3
-
149
-
-
58149193205
-
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
-
Conn PJ, Christopoulos A, Lindsley CW. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders. Nat Rev Drug Discov. 2009;8:41-54.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 41-54
-
-
Conn, P.J.1
Christopoulos, A.2
Lindsley, C.W.3
-
150
-
-
0141569348
-
Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2
-
Schaffhauser H, Rowe BA, Morales S, et al. Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2. Mol Pharmacol. 2003;64:798-810.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 798-810
-
-
Schaffhauser, H.1
Rowe, B.A.2
Morales, S.3
-
151
-
-
0038155299
-
Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2trifluoroethylsulfonyl)pyrid-3-yl methylamine
-
Johnson MP, Baez M, Jagdmann GE, et al. Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2trifluoroethylsulfonyl)pyrid-3-yl methylamine. J Med Chem. 2003;46:3189-3192.
-
(2003)
J Med Chem
, vol.46
, pp. 3189-3192
-
-
Johnson, M.P.1
Baez, M.2
Jagdmann, G.E.3
-
152
-
-
20944447548
-
Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)
-
Johnson MP, Barda D, Britton TC, et al. Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s). Psychopharmacology. 2005;179:271-283.
-
(2005)
Psychopharmacology
, vol.179
, pp. 271-283
-
-
Johnson, M.P.1
Barda, D.2
Britton, T.C.3
-
153
-
-
0347722441
-
N-acetyl cysteine-induced blockade of cocaine-induced reinstatement
-
Baker DA, McFarland K, Lake RW, Shen H, Toda S, Kalivas PW. N-acetyl cysteine-induced blockade of cocaine-induced reinstatement. Ann N Y Acad Sci. 2003;1003:349-351.
-
(2003)
Ann N Y Acad Sci
, vol.1003
, pp. 349-351
-
-
Baker, D.A.1
McFarland, K.2
Lake, R.W.3
Shen, H.4
Toda, S.5
Kalivas, P.W.6
-
154
-
-
0036640537
-
Cerebral cystine uptake: a tale of two transporters
-
McBean GJ. Cerebral cystine uptake: a tale of two transporters. Trends Pharmacol Sci. 2002;23:299-302.
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 299-302
-
-
McBean, G.J.1
-
155
-
-
21844443565
-
Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking
-
Moran MM, McFarland K, Melendez RI, Kalivas PW, Seamans JK. Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. J Neurosci. 2005;25:6389-6393.
-
(2005)
J Neurosci
, vol.25
, pp. 6389-6393
-
-
Moran, M.M.1
McFarland, K.2
Melendez, R.I.3
Kalivas, P.W.4
Seamans, J.K.5
-
156
-
-
37849026004
-
N-acetylcysteine reduces extinction responding and induces enduring reductions in cueand heroin-induced drug-seeking
-
Zhou W, Kalivas PW. N-acetylcysteine reduces extinction responding and induces enduring reductions in cueand heroin-induced drug-seeking. Biol Psychiatry. 2008;63:338-340.
-
(2008)
Biol Psychiatry
, vol.63
, pp. 338-340
-
-
Zhou, W.1
Kalivas, P.W.2
-
157
-
-
33646565030
-
The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaineand food-seeking behavior in rats
-
Peters J, Kalivas PW. The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaineand food-seeking behavior in rats. Psychopharmacology (Berl). 2006;186:143-149.
-
(2006)
Psychopharmacology (Berl)
, vol.186
, pp. 143-149
-
-
Peters, J.1
Kalivas, P.W.2
-
158
-
-
43649090465
-
Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine
-
Baker DA, Madayag A, Kristiansen LV, Meador-Woodruff JH, Haroutunian V, Raju I. Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine. Neuropsychopharmacology. 2008;33:1760-1672.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 1760-1672
-
-
Baker, D.A.1
Madayag, A.2
Kristiansen, L.V.3
Meador-Woodruff, J.H.4
Haroutunian, V.5
Raju, I.6
-
159
-
-
48749112603
-
N-acetyl cysteine as a glutathione precursor for schizophrenia-a double-blind, randomized, placebo-controlled trial
-
Berk M, Copolov D, Dean O, et al. N-acetyl cysteine as a glutathione precursor for schizophrenia-a double-blind, randomized, placebo-controlled trial. Biol Psychiatry. 2008;64:361-368.
-
(2008)
Biol Psychiatry
, vol.64
, pp. 361-368
-
-
Berk, M.1
Copolov, D.2
Dean, O.3
-
160
-
-
0028339034
-
NMDA receptor channels: subunit-specific potentiation by reducing agents
-
Köhr G, Eckardt S, Lüddens H, Monyer H, Seeburg PH. NMDA receptor channels: subunit-specific potentiation by reducing agents. Neuron. 1994;12:1031-1040.
-
(1994)
Neuron
, vol.12
, pp. 1031-1040
-
-
Köhr, G.1
Eckardt, S.2
Lüddens, H.3
Monyer, H.4
Seeburg, P.H.5
-
161
-
-
67650652986
-
Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex?
-
Behrens MM, Sejnowksi TJ. Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex? Neuropharmacology. 2009;57:193-200.
-
(2009)
Neuropharmacology
, vol.57
, pp. 193-200
-
-
Behrens, M.M.1
Sejnowksi, T.J.2
-
162
-
-
0033166537
-
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
-
Tu JC, Xiao B, Naisbitt S, et al. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron. 1999;23:583-592.
-
(1999)
Neuron
, vol.23
, pp. 583-592
-
-
Tu, J.C.1
Xiao, B.2
Naisbitt, S.3
-
163
-
-
0030894148
-
(RS)-2chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus
-
Doherty AJ, Palmer MJ, Henley JM, Collingridge GL, Jane DE. (RS)-2chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology. 1997;36:265-267.
-
(1997)
Neuropharmacology
, vol.36
, pp. 265-267
-
-
Doherty, A.J.1
Palmer, M.J.2
Henley, J.M.3
Collingridge, G.L.4
Jane, D.E.5
-
164
-
-
0035959976
-
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons
-
Pisani A, Gubellini P, Bonsi P, et al. Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons. Neuroscience. 2001;106:579-587.
-
(2001)
Neuroscience
, vol.106
, pp. 579-587
-
-
Pisani, A.1
Gubellini, P.2
Bonsi, P.3
-
165
-
-
0034332480
-
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
-
Awad H, Hubert GW, Smith Y, Levey AI, Conn PJ. Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci. 2000;20:7871-7879.
-
(2000)
J Neurosci
, vol.20
, pp. 7871-7879
-
-
Awad, H.1
Hubert, G.W.2
Smith, Y.3
Levey, A.I.4
Conn, P.J.5
-
166
-
-
0036945935
-
The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity
-
Henry SA, Lehmann-Masten V, Gasparini F, Geyer MA, Markou A. The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity. Neuropharmacology. 2002;43:1199-1209.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1199-1209
-
-
Henry, S.A.1
Lehmann-Masten, V.2
Gasparini, F.3
Geyer, M.A.4
Markou, A.5
-
167
-
-
0037665283
-
Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents
-
Kinney GG, Burno M, Campbell UC, et al. Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents. J Pharmacol Exp Ther. 2003;306:116-123.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 116-123
-
-
Kinney, G.G.1
Burno, M.2
Campbell, U.C.3
-
168
-
-
2942650911
-
Functional interaction Between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors, and dopamine release
-
Homayoun H, Stefani MR, Adams BW, Tamagan GD, Moghaddam B. Functional interaction Between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors, and dopamine release. Neuropsychopharmacology. 2004;29:1259-1269.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1259-1269
-
-
Homayoun, H.1
Stefani, M.R.2
Adams, B.W.3
Tamagan, G.D.4
Moghaddam, B.5
-
169
-
-
5544228283
-
The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP)
-
Campbell UC, Lalwani K, Hernandez L, Kinney GG, Conn PJ, Bristow LJ. The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats. Psychopharmacology (Berl). 2004;175:310-318.
-
(2004)
Psychopharmacology (Berl)
, vol.175
, pp. 310-318
-
-
Campbell, U.C.1
Lalwani, K.2
Hernandez, L.3
Kinney, G.G.4
Conn, P.J.5
Bristow, L.J.6
-
170
-
-
28644440123
-
Bursting of prefrontal cortex neurons in awake rats is regulated by metabotropic glutamate 5 (mGlu5) receptors: rate-dependent influence and interaction with NMDA receptors
-
Homayoun H, Moghaddam B. Bursting of prefrontal cortex neurons in awake rats is regulated by metabotropic glutamate 5 (mGlu5) receptors: rate-dependent influence and interaction with NMDA receptors. Cereb Cortex. 2006;16:93-105.
-
(2006)
Cereb Cortex
, vol.16
, pp. 93-105
-
-
Homayoun, H.1
Moghaddam, B.2
-
171
-
-
57349174038
-
ADX47273 [S-(4-fluorophenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-pipe ridin-1-yl}methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities
-
Liu F, Grauer S, Kelley C, Navarra R, et al. ADX47273 [S-(4-fluorophenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-pipe ridin-1-yl}methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities. J Pharmacol Exp Ther. 2008;327:827-839.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 827-839
-
-
Liu, F.1
Grauer, S.2
Kelley, C.3
Navarra, R.4
-
172
-
-
70350182198
-
Comparison of the mGlu receptor positive allosteric modulator ADX47273 and the mGlu(2/3) receptor agonist LY354740 in tests for antipsychotic-like activity
-
Schlumberger C, Pietraszek M, Gravius A, et al. Comparison of the mGlu receptor positive allosteric modulator ADX47273 and the mGlu(2/3) receptor agonist LY354740 in tests for antipsychotic-like activity. Eur J Pharmacol. 2009;623:73-83.
-
(2009)
Eur J Pharmacol
, vol.623
, pp. 73-83
-
-
Schlumberger, C.1
Pietraszek, M.2
Gravius, A.3
-
173
-
-
43349105701
-
Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia
-
Hashimoto T, Bazmi HH, Mirnics K, Wu Q, Sampson AR, Lewis DA. Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry. 2008;165:479-489.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 479-489
-
-
Hashimoto, T.1
Bazmi, H.H.2
Mirnics, K.3
Wu, Q.4
Sampson, A.R.5
Lewis, D.A.6
-
174
-
-
58149385775
-
Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia
-
Behrens MM, Ali SS, Dugan LL. Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. J Neurosci. 2008;28:13957-13966.
-
(2008)
J Neurosci
, vol.28
, pp. 13957-13966
-
-
Behrens, M.M.1
Ali, S.S.2
Dugan, L.L.3
-
175
-
-
0242475319
-
Interneuron diversity series: inhibitory interneurons and network oscillations in vitro
-
Whittington MA, Traub RD. Interneuron diversity series: inhibitory interneurons and network oscillations in vitro. Trends Neurosci. 2003;26:676-682.
-
(2003)
Trends Neurosci
, vol.26
, pp. 676-682
-
-
Whittington, M.A.1
Traub, R.D.2
-
176
-
-
70450182120
-
Role of GABAA receptors in cognition
-
Mohler H. Role of GABAA receptors in cognition. Biochem Soc Trans. 2009;37:1328-1333.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 1328-1333
-
-
Mohler, H.1
-
177
-
-
67651113930
-
Selective alterations in postsynaptic markers of chandelier cell inputs to cortical pyramidal neurons in subjects with schizophrenia
-
Cruz DA, Weaver CL, Lovallo EM, Melchitzky DS, Lewis DA. Selective alterations in postsynaptic markers of chandelier cell inputs to cortical pyramidal neurons in subjects with schizophrenia. Neuropsychopharmacology. 2009;34:2112-2124.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 2112-2124
-
-
Cruz, D.A.1
Weaver, C.L.2
Lovallo, E.M.3
Melchitzky, D.S.4
Lewis, D.A.5
-
178
-
-
28044453713
-
A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction
-
Yee BK, Keist R, von Boehmer L, et al. A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction. Proc Natl Acad Sci U S A. 2005;102:17154-17159.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 17154-17159
-
-
Yee, B.K.1
Keist, R.2
von Boehmer, L.3
-
179
-
-
30844456191
-
GABA-based therapeutic approaches: GABAA receptor subtype functions
-
Rudolph U, Mohler H. GABA-based therapeutic approaches: GABAA receptor subtype functions. Curr Opin Pharmacol. 2006;6:18-23.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 18-23
-
-
Rudolph, U.1
Mohler, H.2
-
180
-
-
57349167353
-
Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia
-
Lewis DA, Cho RY, Carter CS, et al. Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia. Am J Psychiatry. 2008;165:1585-1593.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1585-1593
-
-
Lewis, D.A.1
Cho, R.Y.2
Carter, C.S.3
-
181
-
-
1842562921
-
10. Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons
-
Okada H, Matsushita N, Kobayashi K, Kobayashi K. 10. Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons. J Neurochem. 2004;89:7-14.
-
(2004)
J Neurochem
, vol.89
, pp. 7-14
-
-
Okada, H.1
Matsushita, N.2
Kobayashi, K.3
Kobayashi, K.4
-
182
-
-
38349193123
-
Muscarinic acetylcholine receptors as CNS drug targets
-
Langmead CJ, Watson J, Reavill C. Muscarinic acetylcholine receptors as CNS drug targets. Pharmacol Ther. 2008;117:232-243.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 232-243
-
-
Langmead, C.J.1
Watson, J.2
Reavill, C.3
-
183
-
-
0031774720
-
International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors
-
Caulfield MP, Birdsall NJ. International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol Rev. 1998;50:279-290.
-
(1998)
Pharmacol Rev
, vol.50
, pp. 279-290
-
-
Caulfield, M.P.1
Birdsall, N.J.2
-
184
-
-
27144524511
-
Effect of rivastigmine in the treatment of behavioral disturbances associated with dementia: review of neuropsychiatric impairment in Alzheimer's disease
-
Grossberg GT. Effect of rivastigmine in the treatment of behavioral disturbances associated with dementia: review of neuropsychiatric impairment in Alzheimer's disease. Curr Med Res Opin. 2005;21:1631-1639.
-
(2005)
Curr Med Res Opin
, vol.21
, pp. 1631-1639
-
-
Grossberg, G.T.1
-
185
-
-
38549149803
-
A systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders
-
Figiel G, Sadowsky C. A systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders. Curr Med Res Opin. 2008;24:157-166.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 157-166
-
-
Figiel, G.1
Sadowsky, C.2
-
186
-
-
48949095543
-
Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia
-
Shekhar A, Potter WZ, Lightfoot J, et al. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. Am J Psychiatry. 2008;165:1033-1039.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1033-1039
-
-
Shekhar, A.1
Potter, W.Z.2
Lightfoot, J.3
-
187
-
-
0037691865
-
Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity
-
Bymaster FP, Carter PA, Yamada M, et al. Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity. Eur J Neurosci. 2003;17:1403-1410.
-
(2003)
Eur J Neurosci
, vol.17
, pp. 1403-1410
-
-
Bymaster, F.P.1
Carter, P.A.2
Yamada, M.3
-
188
-
-
34548362105
-
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
-
Wess J, Eglen RM, Gautam D. Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development. Nat Rev Drug Discov. 2007;6:721-733.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 721-733
-
-
Wess, J.1
Eglen, R.M.2
Gautam, D.3
-
189
-
-
0034975130
-
Low muscarinic receptor binding in prefrontal cortex from subjects with schizophrenia: a study of Brodmann's areas 8, 9, 10, and 46 and the effects of neuroleptic drug treatment
-
Crook JM, Tomaskovic-Crook E, Copolov DL, Dean B. Low muscarinic receptor binding in prefrontal cortex from subjects with schizophrenia: a study of Brodmann's areas 8, 9, 10, and 46 and the effects of neuroleptic drug treatment. Am J Psychiatry. 2001;158:918-925.
-
(2001)
Am J Psychiatry
, vol.158
, pp. 918-925
-
-
Crook, J.M.1
Tomaskovic-Crook, E.2
Copolov, D.L.3
Dean, B.4
-
190
-
-
0036932174
-
Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia
-
Dean B, McLeod M, Keriakous D, McKenzie J, Scarr E. Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry. 2002;7:1083-1091.
-
(2002)
Mol Psychiatry
, vol.7
, pp. 1083-1091
-
-
Dean, B.1
McLeod, M.2
Keriakous, D.3
McKenzie, J.4
Scarr, E.5
-
191
-
-
0037220723
-
Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice
-
Anagnostaras SG, Murphy GG, Hamilton SE, et al. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nat Neurosci. 2003;6:51-58.
-
(2003)
Nat Neurosci
, vol.6
, pp. 51-58
-
-
Anagnostaras, S.G.1
Murphy, G.G.2
Hamilton, S.E.3
-
192
-
-
0035910050
-
Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice
-
Gerber DJ, Sotnikova TD, Gainetdinov RR, Huang SY, Caron MG, Tonegawa S. Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice. Proc Natl Acad Sci U S A. 2001;98:15312-15317.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 15312-15317
-
-
Gerber, D.J.1
Sotnikova, T.D.2
Gainetdinov, R.R.3
Huang, S.Y.4
Caron, M.G.5
Tonegawa, S.6
-
193
-
-
9444239189
-
M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies
-
Tzavara ET, Bymaster FP, Davis RJ, et al. M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies. FASEB J. 2004;18:1410-1412.
-
(2004)
FASEB J
, vol.18
, pp. 1410-1412
-
-
Tzavara, E.T.1
Bymaster, F.P.2
Davis, R.J.3
-
194
-
-
0042575347
-
Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice
-
Tzavara ET, Bymaster FP, Felder CC, et al. Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice. Mol Psychiatry. 2003;8:673-679.
-
(2003)
Mol Psychiatry
, vol.8
, pp. 673-679
-
-
Tzavara, E.T.1
Bymaster, F.P.2
Felder, C.C.3
-
195
-
-
30644461032
-
Modulation of synaptic plasticity by physiological activation of M1 muscarinic acetylcholine receptors in the mouse hippocampus
-
Shinoe T, Matsui M, Taketo MM, Manabe T. Modulation of synaptic plasticity by physiological activation of M1 muscarinic acetylcholine receptors in the mouse hippocampus. J Neurosci. 2005;25:11194-11200.
-
(2005)
J Neurosci
, vol.25
, pp. 11194-11200
-
-
Shinoe, T.1
Matsui, M.2
Taketo, M.M.3
Manabe, T.4
-
196
-
-
0032530817
-
Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-Daspartate (NMDA) receptor currents in hippocampal pyramidal cells
-
Marino MJ, Rouse ST, Levey AI, Potter LT, Conn PJ. Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-Daspartate (NMDA) receptor currents in hippocampal pyramidal cells. Proc Natl Acad Sci U S A. 1998;95:11465-11470.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11465-11470
-
-
Marino, M.J.1
Rouse, S.T.2
Levey, A.I.3
Potter, L.T.4
Conn, P.J.5
-
197
-
-
61349093537
-
Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders
-
Conn PJ, Jones CK, Lindsley CW. Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Trends Pharmacol Sci. 2009;30:148-155.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 148-155
-
-
Conn, P.J.1
Jones, C.K.2
Lindsley, C.W.3
-
198
-
-
37249054670
-
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission
-
Shirey JK, Xiang Z, Orton D, et al. An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nat Chem Biol. 2008;4:42-50.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 42-50
-
-
Shirey, J.K.1
Xiang, Z.2
Orton, D.3
-
199
-
-
55249118679
-
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
-
Jones CK, Brady AE, Davis AA, et al. Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. J Neurosci. 2008;28:10422-10433.
-
(2008)
J Neurosci
, vol.28
, pp. 1042210433
-
-
Jones, C.K.1
Brady, A.E.2
Davis, A.A.3
-
200
-
-
70449640543
-
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
-
Shirey JK, Brady AE, Jones PJ, et al. A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning. J Neurosci. 2009;29:14271-14278.
-
(2009)
J Neurosci
, vol.29
, pp. 14271-14278
-
-
Shirey, J.K.1
Brady, A.E.2
Jones, P.J.3
-
201
-
-
49449108109
-
Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia
-
Chan WY, McKinzie DL, Bose S, et al. Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. Proc Natl Acad Sci U S A. 2008;105:10978-10983.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10978-10983
-
-
Chan, W.Y.1
McKinzie, D.L.2
Bose, S.3
-
202
-
-
57349113845
-
Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamineinduced hyperlocomotor activity in rats
-
Brady AE, Jones CK, Bridges TM, et al. Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamineinduced hyperlocomotor activity in rats. J Pharmacol Exp Ther. 2008;327:941-953.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 941-953
-
-
Brady, A.E.1
Jones, C.K.2
Bridges, T.M.3
-
204
-
-
0032746548
-
Smoking habits, current symptoms, and premorbid characteristics of schizophrenic patients in Nithsdale
-
Kelly C, McCreadie RG. Smoking habits, current symptoms, and premorbid characteristics of schizophrenic patients in Nithsdale, Scotland. Am J Psychiatry. 1999;156:1751-1757.
-
(1999)
Scotland. Am J Psychiatry.
, vol.156
, pp. 1751-1757
-
-
Kelly, C.1
McCreadie, R.G.2
-
205
-
-
11844263996
-
Tobacco use in schizophrenia: a study of cotinine concentrations in the saliva of patients and controls
-
Strand JE, Nyback H. Tobacco use in schizophrenia: a study of cotinine concentrations in the saliva of patients and controls. Eur Psychiatry. 2005;20:50-54.
-
(2005)
Eur Psychiatry
, vol.20
, pp. 50-54
-
-
Strand, J.E.1
Nyback, H.2
-
207
-
-
0031751031
-
Schizophrenia, sensory gating, and nicotinic receptors
-
Adler LE, Olincy A, Waldo M, et al. Schizophrenia, sensory gating, and nicotinic receptors. Schizophr Bull. 1998;24:189-202.
-
(1998)
Schizophr Bull
, vol.24
, pp. 189-202
-
-
Adler, L.E.1
Olincy, A.2
Waldo, M.3
-
208
-
-
0028269519
-
Serum antibodies to nicotinic acetylcholine receptors in schizophrenic patients
-
Mukherjee S, Mahadik SP, Korenovsky A, Laev H, Schnur DB, Reddy R. Serum antibodies to nicotinic acetylcholine receptors in schizophrenic patients. Schizophr Res. 1994;12:131-136.
-
(1994)
Schizophr Res
, vol.12
, pp. 131-136
-
-
Mukherjee, S.1
Mahadik, S.P.2
Korenovsky, A.3
Laev, H.4
Schnur, D.B.5
Reddy, R.6
-
210
-
-
33847029091
-
Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
-
Dani JA, Bertrand D. Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annu Rev Pharmacol Toxicol. 2007;47:699-729.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 699-729
-
-
Dani, J.A.1
Bertrand, D.2
-
211
-
-
0022376548
-
Cholinergic innervation of the rat hippocampus as revealed by choline acetyltransferase immunocytochemistry: a combined light and electron microscopic study
-
Frotscher M, Leranth C. Cholinergic innervation of the rat hippocampus as revealed by choline acetyltransferase immunocytochemistry: a combined light and electron microscopic study. J Comp Neurol. 1985;239:237-246.
-
(1985)
J Comp Neurol
, vol.239
, pp. 237246
-
-
Frotscher, M.1
Leranth, C.2
-
212
-
-
0029805769
-
Hippocampal synaptic transmission enhanced by low concentrations of nicotine
-
Gray R, Rajan AS, Radcliffe KA, Yakehiro M, Dani JA. Hippocampal synaptic transmission enhanced by low concentrations of nicotine. Nature. 1996;383:713-716.
-
(1996)
Nature
, vol.383
, pp. 713-716
-
-
Gray, R.1
Rajan, A.S.2
Radcliffe, K.A.3
Yakehiro, M.4
Dani, J.A.5
-
213
-
-
0034991547
-
Parvalbumin-containing interneurons of the human cerebral cortex express nicotinic acetylcholine receptor proteins
-
Krenz I, Kalkan D, Wevers A, et al. Parvalbumin-containing interneurons of the human cerebral cortex express nicotinic acetylcholine receptor proteins. J Chem Neuroanat. 2001;21:239-246.
-
(2001)
J Chem Neuroanat
, vol.21
, pp. 239-246
-
-
Krenz, I.1
Kalkan, D.2
Wevers, A.3
-
214
-
-
0032531893
-
Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons
-
Frazier CJ, Buhler AV, Weiner JL, Dunwiddie TV. Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. J Neurosci. 1998;18:8228-8235.
-
(1998)
J Neurosci
, vol.18
, pp. 82288235
-
-
Frazier, C.J.1
Buhler, A.V.2
Weiner, J.L.3
Dunwiddie, T.V.4
-
215
-
-
0035282788
-
Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei
-
Klink R, de Kerchove d'Exaerde A, Zoli M, Changeux JP. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. J Neurosci. 2001;21:1452-1463.
-
(2001)
J Neurosci
, vol.21
, pp. 1452-1463
-
-
Klink, R.1
de Kerchove d'Exaerde, A.2
Zoli, M.3
Changeux, J.P.4
-
216
-
-
0037075602
-
Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
-
Mansvelder HD, Keath JR, McGehee DS. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron. 2002;33:905-919.
-
(2002)
Neuron
, vol.33
, pp. 905-919
-
-
Mansvelder, H.D.1
Keath, J.R.2
McGehee, D.S.3
-
217
-
-
0034672822
-
Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area
-
Schilstrom B, Fagerquist MV, Zhang X, et al. Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area. Synapse. 2000;38:375-383.
-
(2000)
Synapse
, vol.38
, pp. 375-383
-
-
Schilstrom, B.1
Fagerquist, M.V.2
Zhang, X.3
-
218
-
-
0032168029
-
Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7)
-
Gault J, Robinson M, Berger R, et al. Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics. 1998;52:173-185.
-
(1998)
Genomics
, vol.52
, pp. 173-185
-
-
Gault, J.1
Robinson, M.2
Berger, R.3
-
219
-
-
0032872325
-
Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus
-
Court J, Spurden D, Lloyd S, et al. Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus. J Neurochem. 1999;73:1590-1597.
-
(1999)
J Neurochem
, vol.73
, pp. 1590-1597
-
-
Court, J.1
Spurden, D.2
Lloyd, S.3
-
220
-
-
0029085870
-
Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
-
Freedman R, Hall M, Adler LE, Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry. 1995;38:22-33.
-
(1995)
Biol Psychiatry
, vol.38
, pp. 22-33
-
-
Freedman, R.1
Hall, M.2
Adler, L.E.3
Leonard, S.4
-
221
-
-
0034945151
-
Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia
-
Marutle A, Zhang X, Court J, et al. Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia. J Chem Neuroanat. 2001;22:115-126.
-
(2001)
J Chem Neuroanat
, vol.22
, pp. 115-126
-
-
Marutle, A.1
Zhang, X.2
Court, J.3
-
222
-
-
0344861848
-
Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia
-
Martin-Ruiz CM, Haroutunian VH, Long P, et al. Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia. Biol Psychiatry. 2003;54:1222-1233.
-
(2003)
Biol Psychiatry
, vol.54
, pp. 1222-1233
-
-
Martin-Ruiz, C.M.1
Haroutunian, V.H.2
Long, P.3
-
223
-
-
1842799731
-
The alpha7 nicotinic acetylcholine receptor in schizophrenia: decreased mRNA levels in peripheral blood lymphocytes
-
Perl O, Ilani T, Strous RD, Lapidus R, Fuchs S. The alpha7 nicotinic acetylcholine receptor in schizophrenia: decreased mRNA levels in peripheral blood lymphocytes. FASEB J. 2003;17:1948-1950.
-
(2003)
FASEB J
, vol.17
, pp. 1948-1950
-
-
Perl, O.1
Ilani, T.2
Strous, R.D.3
Lapidus, R.4
Fuchs, S.5
-
224
-
-
33751334112
-
Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice
-
Young JW, Crawford N, Kelly JS, et al. Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice. Eur Neuropsychopharmacol. 2007;17:145-155.
-
(2007)
Eur Neuropsychopharmacol
, vol.17
, pp. 145-155
-
-
Young, J.W.1
Crawford, N.2
Kelly, J.S.3
-
225
-
-
0037154981
-
Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory
-
Levin ED, Bradley A, Addy N, Sigurani N. Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory. Neuroscience. 2002;109:757-765.
-
(2002)
Neuroscience
, vol.109
, pp. 757-765
-
-
Levin, E.D.1
Bradley, A.2
Addy, N.3
Sigurani, N.4
-
226
-
-
0033237390
-
AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats
-
Levin ED, Bettegowda C, Blosser J, Gordon J. AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats. Behav Pharmacol. 1999;10:675-680.
-
(1999)
Behav Pharmacol
, vol.10
, pp. 675-680
-
-
Levin, E.D.1
Bettegowda, C.2
Blosser, J.3
Gordon, J.4
-
227
-
-
20444483610
-
Tropisetron improves deficits in auditory P50 suppression in schizophrenia
-
Koike K, Hashimoto K, Takai N, et al. Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophr Res. 2005;76:6772.
-
(2005)
Schizophr Res
, vol.76
, pp. 6772
-
-
Koike, K.1
Hashimoto, K.2
Takai, N.3
-
228
-
-
65649092520
-
Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders
-
Roncarati R, Scali C, Comery TA, et al. Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders. J Pharmacol Exp Ther. 2009;329:459-468.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 459-468
-
-
Roncarati, R.1
Scali, C.2
Comery, T.A.3
-
229
-
-
0002100551
-
3[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner
-
Meyer EM, Tay ET, Papke RL, Meyers C, Huang GL, de Fiebre CM. 3[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner. Brain Res. 1997;768:49-56.
-
(1997)
Brain Res
, vol.768
, pp. 49-56
-
-
Meyer, E.M.1
Tay, E.T.2
Papke, R.L.3
Meyers, C.4
Huang, G.L.5
de Fiebre, C.M.6
-
230
-
-
0031003185
-
Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo
-
Briggs CA, Anderson DJ, Brioni JD, et al. Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacol Biochem Behav. 1997;57:231-241.
-
(1997)
Pharmacol Biochem Behav
, vol.57
, pp. 231-241
-
-
Briggs, C.A.1
Anderson, D.J.2
Brioni, J.D.3
-
231
-
-
0042594579
-
Mecamylamine reversal by nicotine and by a partial alpha7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning. Behav
-
Woodruff-Pak DS. Mecamylamine reversal by nicotine and by a partial alpha7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning. Behav Brain Res. 2003;143:159-167.
-
(2003)
Brain Res
, vol.143
, pp. 159167
-
-
Woodruff-Pak, D.S.1
-
232
-
-
0031596817
-
Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice
-
Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998;136:320-327.
-
(1998)
Psychopharmacology (Berl)
, vol.136
, pp. 320-327
-
-
Stevens, K.E.1
Kem, W.R.2
Mahnir, V.M.3
Freedman, R.4
-
233
-
-
0038690569
-
Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers
-
Kitagawa H, Takenouchi T, Azuma R, et al. Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers. Neuropsychopharmacology. 2003;28:542-551.
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 542-551
-
-
Kitagawa, H.1
Takenouchi, T.2
Azuma, R.3
-
234
-
-
33847351996
-
Schizophrenia and the alpha7 nicotinic acetylcholine receptor
-
Martin LF, Freedman R. Schizophrenia and the alpha7 nicotinic acetylcholine receptor. Int Rev Neurobiol. 2007;78:225-246.
-
(2007)
Int Rev Neurobiol
, vol.78
, pp. 225-246
-
-
Martin, L.F.1
Freedman, R.2
-
235
-
-
33744911665
-
et al Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia
-
Olincy A, Harris JG, Johnson LL, et al Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Arch Gen Psychiatry. 2006;63:630-638.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 630-638
-
-
Olincy, A.1
Harris, J.G.2
Johnson, L.L.3
-
236
-
-
48949099564
-
Initial phase 2 trial of a nicotinic agonist in schizophrenia
-
Freedman R, Olincy A, Buchanan RW, et al. Initial phase 2 trial of a nicotinic agonist in schizophrenia. Am J Psychiatry. 2008;165:1040-1047.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1040-1047
-
-
Freedman, R.1
Olincy, A.2
Buchanan, R.W.3
-
237
-
-
76749132562
-
Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia
-
Tregellas JR, Olincy A, Johnson L, et al. Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia. Neuropsychopharmacology. 2010;35:938-942.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 938-942
-
-
Tregellas, J.R.1
Olincy, A.2
Johnson, L.3
-
238
-
-
60049101441
-
Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats
-
Rezvani AH, Kholdebarin E, Brucato FH, Callahan PM, Lowe DA, Levin ED. Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:269-275.
-
(2009)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.33
, pp. 269-275
-
-
Rezvani, A.H.1
Kholdebarin, E.2
Brucato, F.H.3
Callahan, P.M.4
Lowe, D.A.5
Levin, E.D.6
-
239
-
-
33845698922
-
SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: binding and functional profile
-
Biton B, Bergis OE, Galli F, et al. SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: binding and functional profile. Neuropsychopharmacology. 2007;32:1-16.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 1-16
-
-
Biton, B.1
Bergis, O.E.2
Galli, F.3
-
240
-
-
33845719612
-
SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia
-
Pichat P, Bergis OE, Terranova JP, et al. SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia. Neuropsychopharmacology. 2007;32:17-34.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 17-34
-
-
Pichat, P.1
Bergis, O.E.2
Terranova, J.P.3
-
241
-
-
67349167960
-
Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia
-
Barak S, Arad M, De Levie A, Black MD, Griebel G, Weiner I. Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia. Neuropsychopharmacology. 2009;34:1753-1763.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1753-1763
-
-
Barak, S.1
Arad, M.2
De Levie, A.3
Black, M.D.4
Griebel, G.5
Weiner, I.6
-
242
-
-
34548677767
-
Allosteric modulation of nicotinic acetylcholine receptors
-
Bertrand D, Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors. Biochem Pharmacol. 2007;74:1155-1163.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1155-1163
-
-
Bertrand, D.1
Gopalakrishnan, M.2
-
243
-
-
20944441082
-
A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization
-
Hurst RS, Hajos M, Raggenbass M, et al. A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J Neurosci. 2005;25:4396-4405.
-
(2005)
J Neurosci
, vol.25
, pp. 4396-4405
-
-
Hurst, R.S.1
Hajos, M.2
Raggenbass, M.3
-
244
-
-
33747597579
-
Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators
-
Broad LM, Zwart R, Pearson KH, et al. Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators. J Pharmacol Exp Ther. 2006;318:1108-1117.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 1108-1117
-
-
Broad, L.M.1
Zwart, R.2
Pearson, K.H.3
-
245
-
-
55749111553
-
Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site
-
Young GT, Zwart R, Walker AS, Sher E, Millar NS. Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2008;105:14686-14691.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14686-14691
-
-
Young, G.T.1
Zwart, R.2
Walker, A.S.3
Sher, E.4
Millar, N.S.5
-
246
-
-
76849087246
-
Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia
-
Freedman R, Goldowitz D. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Prog Neurobiol. 2010:90:263-275.
-
(2010)
Prog Neurobiol
, vol.90
, pp. 263-275
-
-
Freedman, R.1
Goldowitz, D.2
-
247
-
-
58149359426
-
Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA
-
Liu J, Pearlson G, Windemuth A, Ruano G, Perrone-Bizzozero NI, Calhoun V. Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA. Hum Brain Mapp. 2009;30:241-255.
-
(2009)
Hum Brain Mapp
, vol.30
, pp. 241-255
-
-
Liu, J.1
Pearlson, G.2
Windemuth, A.3
Ruano, G.4
Perrone-Bizzozero, N.I.5
Calhoun, V.6
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