An efficient and enantioselective total synthesis of naturally occurring L-783277

Tetrahedron Letters

Volumn 51, Issue 38, 2010, Pages 4942-4946

  Choi, Hwan Geun ^a   Son, Jung Beom ^a   Park, Dong Sik ^a   Ham, Young Jin ^a   Hah, Jung Mi ^a   Sim, Taebo ^a  

^a Korea Institute of Science and Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLENE; ALDEHYDE; ALKENE; L 783277; LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DEPROTECTION REACTION; ENANTIOSELECTIVITY; MACROLACTONIZATION; SYNTHESIS;

EID: 78049496133     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.07.122     Document Type: Article

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32. 6) δ 11.17 (s, 1H), 6.50 (d, J = 11.8 Hz, 1H), 6.30 (d, J = 2.4 Hz, 1H), 6.28 (d, J = 2.4 Hz, 1H), 6.26-6.19 (m, 1H), 5.32-5.26 (m, 1H), 4.88 (d, J = 4.9 Hz, 1H), 4.69 (d, J = 6.6 Hz, 1H), 4.31-4.29 (m, 1H), 3.74 (m, 1H), 3.73 (s, 3H), 3.09-3.00 (m, 1H), 2.67-2.61 (m, 2H), 2.44-2.36 (m, 1H), 1.63-1.53 (m, 1H), 1.40-1.35 (m, 2H), 1.32 (d, J = 6.2 Hz, 3H);
33. 2) δ 12.12 (s, 1H), 6.36 (dd, J = 3.5 Hz, J = 11.9 Hz, 1H), 6.29 (d, J = 2.6 Hz, 1H), 6.26 (d, J = 2.6 Hz, 1H), 6.21 (dd, J = 2.4 Hz, J = 11.2 Hz, 1H), 5.39-5.36 (m, 3H), 4.48-4.47 (m, 1H), 3.80-3.77 (m, 1H), 3.67 (s, 3H), 3.57 (d, J = 5.2 Hz, 1H), 3.35-3.22 (m, 2H), 2.96-2.88 (m, 1H), 2.54-2.42 (m, 2H), 2.11 (d, J = 10.4 Hz, 1H), 1.39 (d, J = 6.2 Hz, 3H);
34. 3) δ, 200.07, 171.91, 166.63, 164.48, 147.66, 146.42, 126.32, 109.36, 104.59, 99.05, 81.22, 73.10, 73.25, 55.58, 37.24, 36.67, 33.12, 29.05, 20.85.