Learning on multiple timescales in smooth pursuit eye movements

Journal of Neurophysiology

Volumn 104, Issue 5, 2010, Pages 2850-2862

  Yang, Yan ^a   Lisberger, Stephen G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; COGNITION; EYE TRACKING; LEARNING; MALE; MONKEY; MOTION; NONHUMAN; PRIORITY JOURNAL; VELOCITY;

ADULT; ANIMALS; EYE MOVEMENT MEASUREMENTS; HUMANS; LEARNING; MACACA MULATTA; MALE; MODELS, NEUROLOGICAL; MOTION PERCEPTION; PHOTIC STIMULATION; PURSUIT, SMOOTH; REACTION TIME;

EID: 78049489520     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00761.2010     Document Type: Article

References (45)

1. Aizenman CD, Linden DJ. Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons. Nat Neurosci 3: 109-111, 2000.
2. Bedford FL. Perceptual and cognitive spatial learning. J Exp Psychol Hum Percept Perform 19: 517-530, 1993.
3. Boyden ES, Katoh A, Raymond JL. Cerebellum-dependent learning: the role of multiple plasticity mechanisms. Annu Rev Neurosci 27: 581-609, 2004.
4. Brenowitz SD, Regehr WG. Associative short-term synaptic plasticity mediated by endocannainoids. Neuron 45: 419-431, 2005.
5. Brown SP, Brenowitz SD, Regehr WG. Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids. Nat Neurosci 6: 1048-1057, 2003.
6. Cheng S, Sabes PN. Modeling sensorimotor learning with linear dynamical systems. Neural Comput 18: 760-793, 2006.
7. Cheng S, Sabes PN. Calibration of visually guided reaching is driven by error-corrective learning and internal dynamics. J Neurophysiol 97: 3057-3069, 2007.
8. Criscimagna-Hemminger SE, Bastian AJ, Shadmehr AJ. Size of error affects cerebellar contributions to motor learning. J Neurophysiol 103: 2275-2284, 2010.
9. Ethier V, Zee DS, Shadmehr R. Spontaneous recovery of motor memory during saccade adaptation. J Neurophysiol 99: 2577-2583, 2008.
10. Garbutt S, Lisberger SG. Directional cueing of target choice in human smooth pursuit eye movements. J Neurosci 26: 12479-12486, 2006.
11. Gilbert PF, Thach WT. Purkinje cell activity during motor learning. Brain Res 128: 309-328, 1977.
12. Hansel C, Linden DJ. Long-term depression of the cerebellar climbing fiber-Purkinje neuron synapse. Neuron 26: 473-482, 2000.
13. Hansel C, Linden DJ, D'Angelo E. Beyond parallel fiber LTD: the diversity of synaptic and non-synaptic plasticity in the cerebellum. Nat Neurosci 4: 467-475, 2001.
14. Highstein SM. Synaptic linkage in the vestibulo-ocular and cerebello-vestibular pathways to the VIth nucleus in the rabbit. Exp Brain Res 17: 301-314, 1973.
15. Hirata Y, Highstein SM. Acute adaptation of the vestibuloocular reflex: signal processing by floccular and ventral parafloccular Purkinje cells. J Neurophysiol 85: 2267-2288, 2001.
16. Ito M. Neural design of the cerebellar motor control system. Brain Res 40: 81-84, 1972.
17. Ito M. Cerebellar control of the vestibulo-ocular reflex: around the flocculus hypothesis. Annu Rev Neurosci 5: 275-296, 1982.
18. Ito M. Cerebellar long-term depression: characterization, signal transduction, and functional roles. Physiol Rev 81: 1143-1195, 2001.
19. Jorntell H, Ekerot CF. Receptive field plasticity profoundly alters the cutaneous parallel fiber synaptic input to cerebellar neurons in vivo. J Neurosci 23: 9620-9631, 2003.
20. Kahlon M, Lisberger SG. Coordinate system for learning in the smooth pursuit eye movements of monkeys. J Neurosci 16: 7270-7283, 1996.
21. Ke MC, Guo CC, Raymond JL. Elimination of climbing fibers instructive signals during motor learning. Nat Neurosci 12: 1171-1179, 2009.
22. Kowler E, Martins AJ, Pavel M. The effect of expectations on slow oculomotor control. IV. Anticipatory smooth eye movements depend on prior target motions. Vision Res 24: 197-210, 1984.
23. Krauzlis RJ, Lisberger SG. Directional organization of eye movement and visual signals in the floccular lobe of the monkey cerebellum. Exp Brain Res 109: 289-302, 1996.
24. Lee J-Y, Schweighofer N. Dual adaptation supports a parallel architecture of motor memory. J Neurosci 29: 10396-10404, 2009.
25. 2+ transients. Neuron 15: 407-415, 1995.
26. Linden DJ, Dickinson MH, Smeyne M, Connor JA. A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons. Neuron 7: 81-89, 1991.
27. Lisberger SG. Neural basis for motor learning in the vestibuloocular reflex of primates. III. Computational and behavioral analysis of the sites of learning. J Neurophysiol 72: 974-998, 1994.
28. Lisberger SG, Fuchs AF. Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. I. Purkinje cell activity during visually guided horizontal smooth-pursuit eye movements and passive head rotation. J Neurophysiol 41: 733-763, 1978.
29. Medina JF, Carey MR, Lisberger SG. The representation of time for motor learning. Neuron 45: 157-167, 2005.
30. Medina JF, Lisberger SG. Links from complex spikes to local plasticity and motor learning in the cerebellum of awake-behaving monkeys. Nat Neurosci 11: 1185-1192, 2008.
31. Medina JF, Mauk MD. Computer simulation of cerebellar information processing. Nat Neurosci Suppl 3: 1205-1211, 2000.
32. Miles FA, Fuller JH. Visual tracking and the primate flocculus. Science 189: 1000-1002, 1976.
33. Miles FA, Lisberger SG. Plasticity in the vestibulo-ocular reflex: a new hypothesis. Annu Rev Neurosci 4: 273-299, 1981.
34. Newsome WT, Wurtz RH, Dursteler MR, Mikami A. Deficits in visual motion processing following ibotenic acid lesions of the middle temporal visual area of the macaque monkey. J Neurosci 5: 825-840, 1985.
35. Pugh JR, Raman IM. Mechanisms of potentiation of mossy fiber EPSCs in the cerebellar nuclei by coincident synaptic excitation and inhibition. J Neurosci 28: 10549-10560, 2008.
36. Schwartz JD, Lisberger SG. Initial tracking conditions modulate the gain of visuo-motor transmission for smooth pursuit eye movements in monkeys. Vis Neurosci 11: 411-424, 1994.
37. Smith MA, Ghazizadeh A, Shadmehr R. Interacting adaptive processes with different timescales underlie short-term motor learning. PLoS Biol 4: 1035-1043, 2006.
38. Stone LS, Lisberger SG. Visual responses of Purkinje cells in the cerebellar flocculus during smooth-pursuit eye movements in monkeys. I. Simple spikes. J Neurophysiol 63: 1241-1261, 1990a.
39. Stone LS, Lisberger SG. Visual responses of Purkinje cells in the cerebellar flocculus during smooth-pursuit eye movements in monkeys. II. Complex spikes. J Neurophysiol 63: 1262-1275, 1990b.
40. Tabata H, Miura K, Kawano K. Trial-by-trial updating of the gain in preparation for smooth pursuit eye movement based on past experience in humans. J Neurophysiol 99: 747-758, 2008.
41. Tanaka M, Lisberger SG. Regulation of the gain of visually guided smooth-pursuit eye movements by frontal cortex. Nature 409: 191-194, 2001.
42. Telgkamp P, Raman IM. Depression of inhibitory synaptic transmission between Purkinje cells and neurons of the cerebellar nuclei. J Neurosci 22: 8447-8457, 2002.
43. Wells SG, Barnes GR. Fast, anticipatory smooth-pursuit eye movements appear to depend on a short-term store. Exp Brain Res 120: 129-133, 1998.
44. Witney AG, Vetter P, Wolpert DM. The influence of previous experience on predictive motor control. Neuroreport 12: 649-653, 2001.
45. Zhang W, Linden DJ. Long-term depression at the mossy fiber- deep cerebellar nucleus synapse. J Neurosci 26: 6935-6944, 2006.