Toward a hybridization assay using fluorescence resonance energy transfer and quantum dots immobilized in microfluidic channels

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 7750, Issue , 2010, Pages

  Tavares, Anthony J ^a   Petryayeva, Eleonora ^a   Algar, W Russ ^a   Chen, Lu ^a   Krull, Ulrich J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

biosensor; fluorescence resonance energy transfer; microfluidics; oligonucleotides; quantum dots

Indexed keywords

DNA TARGETS; ELECTROKINETIC DELIVERY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HYBRIDIZATION ASSAY; MICROFLUIDIC CHANNEL; MICROFLUIDIC PLATFORMS; MULTIPLEXED DETECTION; NONSPECIFIC ADSORPTION; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE CONJUGATES; PROOF OF CONCEPT; QUANTUM DOT; QUANTUM DOTS; SAMPLE VOLUME; SELECTIVE DETECTION; SOLID-PHASE; STREPTAVIDIN;

ADSORPTION; BIOASSAY; BIOCHIPS; BIOMOLECULES; BIOSENSORS; ENERGY TRANSFER; FLUIDIC DEVICES; FLUORESCENCE; NUCLEIC ACIDS; OLIGONUCLEOTIDES; RESONANCE; SEMICONDUCTOR QUANTUM DOTS;

MICROFLUIDICS;

EID: 78049486088     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.876746     Document Type: Conference Paper

References (25)

1. Algar, W. R., Tavares, A. J., and Krull, U. J., "Beyond labels: A review of the application of quantum dots as integrated components of assays, bioprobes, and biosensors utilizing optical transduction," Anal. Chim. Acta, 673, 1-25 (2010).
2. Algar, W. R., and Krull, U. J., "Quantum dots as donors in fluorescence resonance energy transfer for the bioanalysis of nucleic acids, proteins, and other biological molecules," Anal. Bioanal. Chem., 391(5), 1609-1618 (2008).
3. Clapp, A. R., Medintz, I. L., and Mattoussi, H., "Quantum dot-based resonance energy transfer and its growing application in biology," Phys. Chem. Chem. Phys., 11, 17-45 (2009).
4. Algar, W. R., and Krull, U. J., "Towards multi-colour strategies for the detection of oligonucleotide hybridization using quantum dots as energy donors in fluorescence resonance energy transfer (FRET)," Anal. Chim. Acta, 581(2), 193-201 (2007).
5. Algar, W. R., and Krull, U. J., "Toward a multiplexed solid-phase nucleic acid hybridization assay using quantum dots as donors in fluorescence resonance energy transfer," Anal. Chem., 81(10), 4113-4120 (2009).
6. Algar, W. R., and Krull, U. J., "Interfacial transduction of nucleic acid hybridization using immobilized quantum dots as donors in fluorescence resonance energy transfer," Langmuir, 25(1), 633-638 (2009).
7. Algar, W. R., and Krull, U. J., "Multiplexed interfacial transduction of nucleic acid hybridization using a single color of immobilized quantum dot donor and two acceptors in fluorescence resonance energy transfer," Anal. Chem., 82(1), 400-405 (2010).
8. Algar, W. R., and Krull, U. J., "Developing mixed films of immobilized oligonucleotides and quantum dots for the multiplexed detection of nucleic acid hybridization using a combination of fluorescence resonance energy transfer and direct excitation of fluorescence," Langmuir, 26(8), 6041-6047 (2010).
9. Algar, W. R., and Krull, U. J., "Biological imaging and sensing using nanoparticle assemblies," Mater. Res. Soc. Symp. Proc. 1241E, 1241-XX09-04 (2010).
10. Algar, W. R., and Krull, U. J., "New opportunities in multiplexed optical bioanalyses using quantum dots and donor-acceptor interactions," Anal. Bioanal. Chem., DOI:10.1007/s00216-010-3837-y, (2010).
11. Watterson, J. H., Raha, S., Kotoris, C. C. et al., "Rapid detection of single nucleotide polymorphisms associated with spinal muscular atrophy by use of a reusable fibre-optic biosensor," Nuc. Acids. Res., 32(2), e18 (2004).
12. Erickson, D., Liu, X. Z., Krull, U. J. et al., "Electrokinetically controlled DNA hybridization microfluidic chip enabling rapid target analysis," Anal. Chem., 76(24), 7269-7277 (2004). (Pubitemid 39657997)
13. Wu, Y., Lopez, G. P., Sklar, L. A. et al., "Spectroscopic characterization of streptavidin functionalized quantum dots," Anal. Biochem., 364(2), 193-203 (2007). (Pubitemid 46559915)
14. Pons, T., Medintz, I. L., Sapsford, K. E. et al., "On the quenching of semiconductor quantum dot photoluminescence by proximal gold nanoparticles," Nano Lett., 7(10), 3157-3164 (2007). (Pubitemid 350132946)
15. Algar, W. R., Lim, Y., Massey, M. et al., [Soft Nanomaterials 2] American Scientific Publishers, California, 18-23 (2009).
16. Green, N. M., and Joynson, M. A., "A preliminary crystallographic investigation of avidin," Biochem. J., 118(1), 71-72 (1970).
17. Yu, W. W., Qu, L. H., Guo, W. Z. et al., "Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals," Chem. Mater., 15(14), 2854-2860 (2003).
18. Zhang, C. Y., Yeh, H. C., Kuroki, M. T. et al., "Single-quantum-dot- based DNA nanosensor," Nat. Mater., 4(11), 826-831 (2005).
19. Algar, W. R., and Krull, U. J., "Adsorption and hybridization of oligonucleotides on mercaptoacetic acid capped CdSe/ZnS quantum dots and quantum dot-oligonucleotide conjugates," Langmuir, 22(26), 11346-11352 (2006).
20. Algar, W. R., and Krull, U. J., "Multidentate surface ligand exchange for the immobilization of CdSe/ZnS quantum dots and surface quantum dot-oligonucleotide conjugates," Langmuir, 24(10), 5514-5520 (2008).
21. Kim, Y. P., Oh, Y. H., Oh, E. et al., "Chip-based protease assay using fluorescence resonance energy transfer between quantum dots and fluorophores," Biochip J., 1(4), 228-233 (2007).
22. Kim, Y. P., Oh, Y. H., Oh, E. et al., "Energy transfer-based multiplexed assay of protease by using gold nanoparticle and quantum dot conjugates on a surface," Anal. Chem., 80(12), 4634-4641 (2008). (Pubitemid 351842342)
23. Swift, J. L., Heuff, R., and Cramb, D. T., "A two-photon excitation fluorescence cross-correlation assay for a model ligand-receptor binding system using quantum dots," Biophys. J., 90(4), 1396-1410 (2006).
24. Sanborn, M. E., Connolly, B. K., Gurunathan, K. et al., "Fluorescence properties and photophysics of the sulfoindocyanine Cy3 linked covalently to DNA," J. Phys. Chem. B, 111(37), 11064-11074 (2007). (Pubitemid 47522599)
25. Erickson, D., Liu, X. Z., Venditti, R. et al., "Electrokinetically based approach for single-nucleotide polymorphism discrimination using a microfluidic device," Anal. Chem., 77(13), 4000-4007 (2005). (Pubitemid 40934264)