Diagnosis: Use of clinical probability algorithms

Clinics in Chest Medicine

Volumn 31, Issue 4, 2010, Pages 629-639

  Gandara, Esteban ^a,b   Wells, Philip S ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

D dimer; Diagnosis; Outcome assessment; Pulmonary embolism

Indexed keywords

D DIMER;

ALGORITHM; ANAMNESIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC TEST; DISEASE CLASSIFICATION; ELECTROCARDIOGRAM; HIGH RISK POPULATION; HUMAN; INTERMETHOD COMPARISON; LUNG EMBOLISM; PHYSICAL EXAMINATION; PREDICTION; PRIORITY JOURNAL; PROBABILITY; PROTEIN ANALYSIS; REVIEW; RISK FACTOR; STATISTICAL MODEL; THORAX RADIOGRAPHY;

ALGORITHMS; DECISION SUPPORT TECHNIQUES; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; MEDICAL HISTORY TAKING; MODELS, STATISTICAL; PHYSICAL EXAMINATION; PULMONARY EMBOLISM;

EID: 78049481621     PISSN: 02725231     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccm.2010.07.002     Document Type: Review

References (81)

1. Spencer F.A., Emery C., Lessard D., et al. A population-based study of the clinical epidemiology of venous thromboembolism. J Gen Intern Med 2006, 21:722-727.
2. Stein P.D., Henry J.W., Relyea B. Untreated patients with pulmonary embolism. Outcome, clinical, and laboratory assessment. Chest 1995, 107:931-935.
3. Dalen J.E., Alpert J.S. Natural history of pulmonary embolism. Prog Cardiovasc Dis 1975, 17:259-270.
4. Heit J.A., Silverstein M.D., Mohr D.N., et al. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med 2000, 160:809-815.
5. Heit J.A., O'Fallon W.M., Petterson T.M., et al. Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a population-based study. Arch Intern Med 2002, 162:1245-1248.
6. Heit J.A., Cohen A.T., Anderson F.A. Estimated annual number of incident and recurrent, non-fatal and fatal venous thromboembolism (VTE) events in the US [abstract]. Blood 2005, 106:910.
7. Roy P.M., Meyer G., Vielle B., et al. Appropriateness of diagnostic management and outcomes of suspected pulmonary embolism. Ann Intern Med 2006, 144:157-164.
8. Roy P.M., Colombet I., Durieux P., et al. Systematic review and meta-analysis of strategies for the diagnosis of suspected pulmonary embolism. BMJ 2005, 331:259-268.
9. Park B., Messina L., Dargon P., et al. Recent trends in clinical outcomes and resource utilization for pulmonary embolism in the United States: findings from the nationwide inpatient sample. Chest 2009, 136:983-990.
10. Burge A.J., Freeman K.D., Klapper P.J., et al. Increased diagnosis of pulmonary embolism without a corresponding decline in mortality during the CT era. Clin Radiol 2008, 63:381-386.
11. Costantino M.M., Randall G., Gosselin M., et al. CT angiography in the evaluation of acute pulmonary embolus. AJR Am J Roentgenol 2008, 191:471-474.
12. Lobo J.L., Zorrilla V., Aizpuru F., et al. Clinical syndromes and clinical outcome in patients with pulmonary embolism: findings from the RIETE registry. Chest 2006, 130:1817-1822.
13. Miniati M., Prediletto R., Formichi B., et al. Accuracy of clinical assessment in the diagnosis of pulmonary embolism. Am J Respir Crit Care Med 1999, 159:864-871.
14. Stein P.D., Beemath A., Matta F., et al. Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II. Am J Med 2007, 120:871-879.
15. West J., Goodacre S., Sampson F. The value of clinical features in the diagnosis of acute pulmonary embolism: systematic review and meta-analysis. QJM 2007, 100:763-769.
16. Aujesky D., Roy P.M., Le Manach C.P., et al. Validation of a model to predict adverse outcomes in patients with pulmonary embolism. Eur Heart J 2006, 27:476-481.
17. Miniati M., Bottai M., Monti S., et al. Simple and accurate prediction of the clinical probability of pulmonary embolism. Am J Respir Crit Care Med 2008, 178:290-294.
18. Le Gal G., Testuz A., Righini M., et al. Reproduction of chest pain by palpitation: diagnostic accuracy in suspected pulmonary embolism. BMJ 2005, 330:452-453.
19. Righini M., Le Gal G., Perrier A., et al. The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategies. J Am Geriatr Soc 2005, 53:1039-1045.
20. Righini M., Nendaz M., Le Gal G., et al. Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolism. J Thromb Haemost 2007, 5:1869-1877.
21. Bergus G.R., Barloon T.S., Kahn D. An approach to diagnostic imaging of suspected pulmonary embolism. Am Fam Physician 1996, 53:1259-1266.
22. Rissanen V., Suomalainen O., Karjalainen P., et al. Screening for postoperative pulmonary embolism on the basis of clinical symptomatology, routine electrocardiography and plain chest radiography. Acta Med Scand 1984, 215:13-19.
23. Stein P.D., Terrin M.L., Hales C.A., et al. Clinical, laboratory, roentgenographic, and electrocardiographic findings in patients with acute pulmonary embolism and no pre-existing cardiac or pulmonary disease. Chest 1991, 100:598-603.
24. Stein P.D., Alavi A., Gottschalk A., et al. Usefulness of noninvasive diagnostic tools for diagnosis of acute pulmonary embolism in patients with a normal chest radiograph. Am J Cardiol 1991, 67:1117-1120.
25. Fruergaard P., Launbjerg J., Hesse B. Frequency of pulmonary embolism in patients admitted with chest pain and suspicion of acute myocardial infarction but in whom this diagnosis is ruled out. Cardiology 1996, 87:331-334.
26. Rodger M.A., Makropoulos D., Turek M., et al. Diagnostic value of the electrocardiogram in suspected pulmonary embolism. Am J Cardiol 2000, 86:807-809.
27. Stein P.D., Dalen J.E., McIntyre K.M., et al. The electrocardiogram in acute pulmonary embolism. Prog Cardiovasc Dis 1975, 17:247-257.
28. Miniati M., Monti S., Bauleo C., et al. A diagnostic strategy for pulmonary embolism based on standardised pretest probability and perfusion lung scanning: a management study. Eur J Nucl Med Mol Imaging 2003, 30:1450-1456.
29. Rodger M.A., Bredeson C.N., Jones G., et al. The bedside investigation of pulmonary embolism diagnosis study: a double-blind randomized controlled trial comparing combinations of 3 bedside tests vs ventilation-perfusion scan for the initial investigation of suspected pulmonary embolism. Arch Intern Med 2006, 166:181-187.
30. Wells P.S., Ginsberg J.S., Anderson D.R., et al. Use of a clinical model for safe management of patients with suspected pulmonary embolism. Ann Intern Med 1998, 129:997-1005.
31. Wells P.S., Hirsh J., Anderson D.R., et al. A simple clinical model for the diagnosis of deep-vein thrombosis combined with impedance plethysmography: potential for an improvement in the diagnostic process. J Intern Med 1998, 243:15-23.
32. Wells P.S., Anderson D.R., Rodger M.A., et al. Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost 2000, 83:416-420.
33. Bayes T. An essay towards solving a problem in the doctrine of chances. Philos Trans R Soc Lond 1763, 53:370-418.
34. Chunilal S.D., Eikelboom J.W., Attia J., et al. Does this patient have pulmonary embolism?. JAMA 2003, 290:2849-2858.
35. Wicki J., Perneger T.V., Junod A.F., et al. Assessing clinical probability of pulmonary embolism in the emergency ward: a simple score. Arch Intern Med 2001, 161:92-97.
36. Perrier A., Roy P.-M., Aujesky D., et al. Diagnosing pulmonary embolism in outpatients with clinical assessment, D-dimer measurement, venous ultrasound, and helical computed tomography: a multicenter management study. Am J Med 2004, 116:291-299.
37. Perrier A., Roy P.M., Sanchez O., et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005, 352:1760-1768.
38. Righini M., Le Gal G., Aujesky D., et al. Diagnosis of pulmonary embolism by multidetector CT alone or combined with venous ultrasonography of the leg: a randomised non-inferiority trial. Lancet 2008, 371:1343-1352.
39. Klok F.A., Mos I.C., Nijkeuter M., et al. Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med 2008, 168:2131-2136.
40. Kline J.A., Mitchell A.M., Kabrhel C., et al. Clinical criteria to prevent unnecessary diagnostic testing in emergency department patients with suspected pulmonary embolism. J Thromb Haemost 2004, 2:1247-1255.
41. Kline J.A., Nelson R.D., Jackson R.E., et al. Criteria for the safe use of D-dimer testing in emergency department patients with suspected pulmonary embolism: a multicenter US study. Ann Emerg Med 2002, 39:144-152.
42. Hogg K., Dawson D., Kline J. Application of pulmonary embolism rule-out criteria to the UK Manchester Investigation of Pulmonary Embolism Diagnosis (MIOPED) study cohort. J Thromb Haemost 2005, 3:592-593.
43. Kline J.A., Courtney D.M., Kabhel C., et al. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost 2008, 6:772-780.
44. Miniati M., Monti S., Bottai M. A structured clinical model for predicting the probability of pulmonary embolism. Am J Med 2003, 114:173-179.
45. Miniati M., Bottai M., Monti S. Comparison of 3 clinical models for predicting the probability of pulmonary embolism. Medicine (Baltimore) 2005, 84:107-114.
46. Pasha S.M., Klok F.A., Snoep J.D., et al. Safety of excluding acute pulmonary embolism based on an unlikely clinical probability by the Wells rule and normal D-dimer concentration: a meta-analysis. Thromb Res 2010, 125:e123-e127.
47. van Belle A., Buller H.R., Huisman M.V., et al. Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA 2006, 295:172-179.
48. Goekoop R.J., Steeghs N., Niessen R.W., et al. Simple and safe exclusion of pulmonary embolism in outpatients using quantitative D-dimer and Wells' simplified decision rule. Thromb Haemost 2007, 97:146-150.
49. Anderson D.R., Kahn S.R., Rodger M.A., et al. Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial. JAMA 2007, 298:2743-2753.
50. Wolf S.J., McCubbin T.R., Feldhaus K.M., et al. Prospective validation of Wells Criteria in the evaluation of patients with suspected pulmonary embolism. Ann Emerg Med 2004, 44:503-510.
51. Rodger M.A., Maser E., Stiell I., et al. The interobserver reliability of pretest probability assessment in patients with suspected pulmonary embolism. Thromb Res 2005, 116:101-107.
52. Penaloza A., Mélot C., Dochy E., et al. Assessment of pretest probability of pulmonary embolism in the emergency department by physicians in training using the Wells model. Thromb Res 2007, 120:173-179.
53. Gibson N.S., Sohne M., Gerdes V.E., et al. Further validation and simplification of the Wells clinical decision rule in pulmonary embolism. Thromb Haemost 2008, 99:229-234.
54. Testuz A., Le Gal G., Righini M., et al. Influence of specific alternative diagnoses on the probability of pulmonary embolism. Thromb Haemost 2006, 95:958-962.
55. Kline J.A., Runyon M.S., Webb W.B., et al. Prospective study of the diagnostic accuracy of the Simplify D-dimer assay for pulmonary embolism in emergency department patients. Chest 2006, 129:1417-1423.
56. Iles S., Hodges A.M., Darley J.R., et al. Clinical experience and pre-test probability scores in the diagnosis of pulmonary embolism. QJM 2003, 96:211-215.
57. Wells P.S., Anderson D.R., Rodger M.A., et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer. Ann Intern Med 2001, 135:98-107.
58. Stein P.D., Hull R.D., Patel K.C., et al. D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism. A systematic review. Ann Intern Med 2004, 140:589-602.
59. Righini M., Aujesky D., Roy P.M., et al. Clinical usefulness of D-dimer depending on clinical probability and cutoff value in outpatients with suspected pulmonary embolism. Arch Intern Med 2004, 164:2483-2487.
60. Carrier M., Righini M., Djurabi R.K., et al. VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonary embolism. A systematic review of management outcome studies. Thromb Haemost 2009, 101:886-892.
61. Le Gal G., Righini M., Roy P.M., et al. Differential value of risk factors and clinical signs for diagnosing pulmonary embolism according to age. J Thromb Haemost 2005, 3:2457-2464.
62. Di Nisio M., Sohne M., Kamphuisen P.W., et al. D-dimer test in cancer patients with suspected acute pulmonary embolism. J Thromb Haemost 2005, 3:1239-1242.
63. Siragusa S., Anastasio R., Porta C., et al. Deferment of objective assessment of deep vein thrombosis and pulmonary embolism without increased risk of thrombosis: a practical approach based on the pretest clinical model, D-dimer testing, and the use of low-molecular-weight heparins. Arch Intern Med 2004, 164:2477-2482.
64. Bauld D.L., Kovacs M.J. Dalteparin in emergency patients to prevent admission prior to investigation for venous thromboembolism. Am J Emerg Med 1999, 17:11-14.
65. Hayashino Y., Goto M., Noguchi Y., et al. Ventilation-perfusion scanning and helical CT in suspected pulmonary embolism: meta-analysis of diagnostic performance. Radiology 2005, 234:740-748.
66. Stein P.D., Fowler S.E., Goodman L.R., et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006, 354:2317-2327.
67. Ghanima W., Almaas V., Aballi S., et al. Management of suspected pulmonary embolism (PE) by D-dimer and multi-slice computed tomography in outpatients: an outcome study. J Thromb Haemost 2005, 3:1926-1932.
68. Stein P.D., Sostman H.D., Bounameaux H., et al. Challenges in the diagnosis acute pulmonary embolism. Am J Med 2008, 121:565-571.
69. Ranji S.R., Shojania K.G., Trowbridge R.L., et al. Impact of reliance on CT pulmonary angiography on diagnosis of pulmonary embolism: a Bayesian analysis. J Hosp Med 2006, 1:81-87.
70. Stein P.D., Henry J.W., Gottschalk A. Reassessment of pulmonary angiography for the diagnosis of pulmonary embolism: relation of interpreter agreement to the order of the involved pulmonary arterial branch. Radiology 1999, 210:689-691.
71. Rodger M.A., Jones G., Raymond F., et al. Dead space ventilation parallels changes in scintigraphic vascular obstruction at recurrence of pulmonary embolism and after thrombolytic therapy: a case report. Can Respir J 1998, 5:215-218.
72. Rodger M.A., Jones G., Djunaedi H., et al. Inter-observer reliability of alveolar dead space measurements in suspected pulmonary embolism. Can J Respir Ther 2004, 40:24-30.
73. Rodger M.A., Jones G., Rasuli P., et al. Steady-state end-tidal alveolar dead space fraction and D-dimer: bedside tests to exclude pulmonary embolism. Chest 2001, 120:115-119.
74. Kline J.A., Israel E.G., Michelson E.A., et al. Diagnostic accuracy of a bedside D-dimer assay and alveolar dead-space measurement for rapid exclusion of pulmonary embolism: a multicenter study. JAMA 2001, 285:761-768.
75. Sanchez O., Wermert D., Faisy C., et al. Clinical probability and alveolar dead space measurement for suspected pulmonary embolism in patients with an abnormal D-dimer test result. J Thromb Haemost 2006, 4:1517-1522.
76. Wells P.S. Pulmonary embolism: a clinician's perspective. Semin Nucl Med 2008, 38:404-411.
77. Kabrhel C., Camargo C.A., Goldhaber S.Z. Clinical gestalt and the diagnosis of pulmonary embolism: does experience matter?. Chest 2005, 127:1627-1630.
78. Kabrhel C., McAfee A.T., Goldhaber S.Z. The contribution of the subjective component of the Canadian Pulmonary Embolism Score to the overall score in emergency department patients. Acad Emerg Med 2005, 12:915-920.
79. Corwin M.T., Donohoo J.H., Partridge R., et al. Do emergency physicians use serum D-dimer effectively to determine the need for CT when evaluating patients for pulmonary embolism? Review of 5,344 consecutive patients. AJR Am J Roentgenol 2009, 192:1319-1323.
80. Arnason T., Wells P.S., Forster A.J. Appropriateness of diagnostic strategies for evaluating suspected venous thromboembolism. Thromb Haemost 2007, 97:195-201.
81. Roy P.M., Durieux P., Gillaizeau F., et al. A computerized handheld decision-support system to improve pulmonary embolism diagnosis: a randomized trial. Ann Intern Med 2010, 151:677-686.