Chromatin-bound PCNA as S-phase marker in mononuclear blood cells of patients with acute lymphoblastic leukaemia or multiple myeloma

Cell Proliferation

Volumn 43, Issue 6, 2010, Pages 579-583

  Zolzer F ^a,b   Basu, O ^a   Devi, P U ^c   Mohanty, S P ^c   Streffer, C ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^c KASTURBA MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; DNA; PEPSIN A;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CELL CYCLE S PHASE; CHILD; CHROMATIN; CLINICAL ARTICLE; CORRELATION ANALYSIS; CYTOFLUOROMETRY; DNA DETERMINATION; HISTOGRAM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INFANT; MONONUCLEAR CELL; MULTIPLE MYELOMA;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CHROMATIN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; HUMANS; INFANT; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; MULTIPLE MYELOMA; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROLIFERATING CELL NUCLEAR ANTIGEN; S PHASE; STAINING AND LABELING; TUMOR MARKERS, BIOLOGICAL;

EID: 78049480266     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2010.00707.x     Document Type: Article

References (30)

1. Bravo R, Frank R, Blundell PA, Macdonald-Bravo H (1987) Cyclin/PCNA is the auxiliary protein of DNA-polymerase-δ. Nature 326, 515-517.
2. Prelich G, Tan CK, Kostura M, Mathews MB, So AG, Downey KM et al. (1987) Functional identity of proliferating cell nuclear antigen and DNA polymerase δ auxiliary protein. Nature 326, 517-520.
3. Nakayasu H, Berezney R (1989) Mapping replicational sites in the eucaryotic cell nucleus. J. Cell Biol. 108, 1-11.
4. Somanathan S, Suchya TM, Siegel AJ, Berezney R (2001) Targeting of PCNA replication in the mammalian cell nucleus. J. Cell. Biochem. 81, 56-67.
5. Masuda Y, Suzuki M, Piao J, Gu Y, Tsurimoto T, Kamiya K (2007) Dynamics of human replication factors in the elongation phase of DNA replication. Nucleic Acids Res. 35, 6904-6916.
6. Scovassi AI, Prosperi E (2006) Analysis of proliferating cell nuclear antigen (PCNA) associated with DNA. Methods Mol. Biol. 314, 457-475.
7. Wang SC, Nakajima Y, Yu YL, Xia W, Chen CT, Yang CC et al. (2006) Tyrosine phosphorylation controls PCNA function through protein stability. Nat. Cell Biol. 8, 1359-1368.
8. Kurki P, Ogata K, Tan EM (1988) Monoclonal antibodies to proliferating cell nuclear antigen (PCNA)/cyclin as probes for proliferating cells by immunofluorescence microscopy and flow cytometry. J. Immunol. Methods 109, 49-59.
9. Scott RJ, Hall PA, Haldane JS, Van Noorden S, Price Y, Lane DP et al. (1991) A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction. J. Pathol. 165, 173-178.
10. Gelb AB, Kamel OW, LeBrun DP, Warnke RA (1992) Estimation of tumor growth fractions in archival formalin-fixed, paraffin-embedded tissues using two anti-PCNA/Cyclin monoclonal antibodies. Factors affecting reactivity. Am. J. Pathol. 141, 1453-1458.
11. Lin CW, Mashouri T, Jilani I, Neuberg D, Patel K, Kantarjian H et al. (2002) Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome. Leuk. Res. 26, 551-559.
12. Dusek J, Scudla V, Kolar Z, Rihakova P, Hlobilova A (2000) Některé biologické charakteristiky mnohotného myelomu. Českoslov. Patol. 36, 111-115.
13. Tsurusawa M, Ito M, Zha Z, Kawai S, Takasaki Y, Fujimoto T (1992) Cell-cycle-associated expressions of proliferating cell nuclear antigen and Ki-67 reactive antigen of bone marrow blast cells in childhood acute leukemia. Leukemia 6, 669-674.
14. Zölzer F, Streffer C, Pelzer T (1994) A comparison of different methods to determine cell proliferation by flow cytometry. Cell Prolif. 27, 685-694.
15. Nakane PK, Moriuchi T, Koji T, Taniguchi Y, Izumi S, Hui L (1989) Proliferating cell nuclear antigen (PCNA/cyclin): review and some new findings. Acta Histochem. Cytochem. 22, 105-116.
16. Landberg G, Roos G (1992) Flow cytometric analysis of proliferation associated nuclear antigens using washless staining of unfixed cells. Cytometry 13, 230-240.
17. Bravo R, Macdonald-Bravo H (1987) Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites. J. Cell Biol. 105, 1549-1554.
18. Lohr F, Wenz F, Haas S, Flentje M (1995) Comparison of proliferating cell nuclear antigen (PCNA) staining and BrdUrd-labelling index under different proliferative conditions in vitro by flow cytometry. Cell Prolif. 28, 93-104.
19. Larsen JK, Landberg G, Roos G (2001) Detection of proliferating cell nuclear antigen. Methods Cell Biol. 63, 419-431.
20. Dolbaere F, Gratzner H, Pallavicini MG, Gray JW (1983) Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine. Proc. Natl. Acad. Sci. USA 80, 5573-5577.
21. Smets LA, Slater R, Van Wering ER, Van Der Does-van den Berg A, Hart AA, Veerman AJ et al. (1995) DNA index and %S-phase cells determined in acute lymphoblastic leukemia of children: a report from studies ALL V, ALL VI, and ALL VII (1979-1991) of the Dutch Childhood Leukemia Study Group and The Netherlands Workgroup on Cancer Genetics and Cytogenetics. Med. Pediatr. Oncol. 25, 437-444.
22. Orfao A, Ciudad J, González M, San Miguel JF, García AR, López-Berges MC et al. (1992) Prognostic value of S-phase white blood cell count in B-cell chronic lymphocytic leukemia. Leukemia 6, 47-51.
23. Vidriales MB, Orfao A, López-Berges MC, González M, López-Macedo A, Ciudad J et al. (1995) Prognostic value of S-phase cells in AML patients. Br. J. Haematol. 89, 342-348.
24. Tripathi AK, Chaturvedi R, Ahmad R, Asim M, Sawlani KK, Singh MK et al. (2003) Flow cytometric analysis of aneuploidy and S-phase fraction in chronic myeloid leukemia patients: role in early detection of accelerated phase. Leuk. Res. 27, 899-902.
25. Tripathy AK, Tripathy P, Ahmad R, Chaudhary PD, Verma SK (2009) S-phase fraction as response marker in patients with chronic myeloid leukaemia. Leuk. Lymphoma 50, 1223-1225.
26. Kumar V, Varma N, Varma S, Vohra H, Malhotra P, Dutta U et al. (2004) Flow cytometric analysis of DNA indices, expression of p53 and multidrug resistance genes in multiple myeloma patients. Anal. Quant. Cytol. Histol. 26, 271-277.
27. García-Sanz R, González-Fraile MI, Mateo G, Hernández JM, López-Berges MC, De Las Heras N et al. (2004) Proliferative activity of plasma cells is the most relevant prognostic factor in elderly multiple myeloma patients. Int. J. Cancer 112, 884-889.
28. Basu O, Zölzer F, Uma Devi P, Streffer C (2009) DNA-ploidy - a prognostic factor of acute lymphoblastic leukaemia (ALL) in childhood. Asian J. Exp. Sci. 23, 33-38.
29. Mohanty SP, Reddy KR, Devi PU, Rao BS, Rao AV, Prasanna RM (1996) Prognostic assays in multiple myeloma: correlated with flow cytometry. Indian J. Exp. Biol. 34, 870-873.
30. 2-phase cells in human colorectal carcinomas: a flow cytometric study with the Ki67 antibody. Cell Prolif. 28, 313-327.