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Volumn 45, Issue 11, 2010, Pages 2203-2209

Protective effect of tadalafil on ischemia/reperfusion injury of rat ovary

Author keywords

Ischemia reperfusion; Ovary; Rat; Tadalafil

Indexed keywords

CATALASE; LIFTA; MALONALDEHYDE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; TADALAFIL; UNCLASSIFIED DRUG;

EID: 78049474906     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2010.07.011     Document Type: Article
Times cited : (46)

References (52)
  • 1
    • 0346777376 scopus 로고    scopus 로고
    • Minimal surgery for the twisted ischemic adnexa can preserve ovarian function
    • Oelsner G., Cohen S.B., and Soriano D. Minimal surgery for the twisted ischemic adnexa can preserve ovarian function Hum Reprod 18 2003 2599 2602
    • (2003) Hum Reprod , vol.18 , pp. 2599-2602
    • Oelsner, G.1    Cohen, S.B.2    Soriano, D.3
  • 2
    • 0028586741 scopus 로고
    • Adnexal torsion: Can the adnexa be saved
    • Bayer A.I., and Wiskind A.K. Adnexal torsion: can the adnexa be saved Am J Obstet Gynecol 171 1994 1506 1511
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 1506-1511
    • Bayer, A.I.1    Wiskind, A.K.2
  • 3
    • 0031789385 scopus 로고    scopus 로고
    • The effects of twisted ischemic adnexa managed by detorsion on ovarian viability and histology: An ischemia-reperfusion rodent model
    • Taskin O., Birincioglu M., and Aydin A. The effects of twisted ischemic adnexa managed by detorsion on ovarian viability and histology: an ischemia-reperfusion rodent model Hum Reprod 13 1998 2823 2827
    • (1998) Hum Reprod , vol.13 , pp. 2823-2827
    • Taskin, O.1    Birincioglu, M.2    Aydin, A.3
  • 4
    • 0036852092 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury of rat ovary and the effects of vitamin C, mannitol and verapamil
    • Sagsoz N., Kisa U., and Apan A. Ischemia-reperfusion injury of rat ovary and the effects of vitamin C, mannitol and verapamil Hum Reprod 17 2002 2972 2976
    • (2002) Hum Reprod , vol.17 , pp. 2972-2976
    • Sagsoz, N.1    Kisa, U.2    Apan, A.3
  • 5
    • 0027739963 scopus 로고
    • Reperfusion injury after detorsion of unilateral testicular torsion
    • Akgur F.M., KIlInc K., and Aktug T. Reperfusion injury after detorsion of unilateral testicular torsion Urol Res 21 1993 395 399
    • (1993) Urol Res , vol.21 , pp. 395-399
    • Akgur, F.M.1    Kilinc, K.2    Aktug, T.3
  • 6
    • 0036080614 scopus 로고    scopus 로고
    • Reactive species mechanisms of cellular hypoxireoxygenation injury
    • Li C., and Jackson R.M. Reactive species mechanisms of cellular hypoxireoxygenation injury Am J Physiol (Cell Physiol) 282 2002 227 241
    • (2002) Am J Physiol (Cell Physiol) , vol.282 , pp. 227-241
    • Li, C.1    Jackson, R.M.2
  • 7
    • 0021984681 scopus 로고
    • Oxygen-derived free radicals in postischemic tissue injury
    • McCord J.M. Oxygen-derived free radicals in postischemic tissue injury N Engl J Med 312 1985 159 163
    • (1985) N Engl J Med , vol.312 , pp. 159-163
    • McCord, J.M.1
  • 9
    • 4043060632 scopus 로고    scopus 로고
    • Postconditioning: A form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway
    • Tsang A., Hausenloy D.J., and Mocanu M.M. Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway Circ Res 95 2004 230 232
    • (2004) Circ Res , vol.95 , pp. 230-232
    • Tsang, A.1    Hausenloy, D.J.2    Mocanu, M.M.3
  • 10
    • 2942639674 scopus 로고    scopus 로고
    • Moderate exercise with a dietary vitamin C and e combination protects against streptozotocin-induced oxidative damage to the blood and improves fetal outcomes in pregnant rats
    • Naziroglu M., Simşek M., and Kutlu M. Moderate exercise with a dietary vitamin C and E combination protects against streptozotocin-induced oxidative damage to the blood and improves fetal outcomes in pregnant rats Clin Chem Lab Med 42 2004 511 517
    • (2004) Clin Chem Lab Med , vol.42 , pp. 511-517
    • Naziroglu, M.1    Simşek, M.2    Kutlu, M.3
  • 11
    • 34249283797 scopus 로고    scopus 로고
    • Protective effects of lamotrigine, aripiprazole and escitalopram on depression-induced oxidative stress in rat brain
    • Eren I., Naziroglu M., and Demirdas A. Protective effects of lamotrigine, aripiprazole and escitalopram on depression-induced oxidative stress in rat brain Neurochem Res 32 2007 1188 1195
    • (2007) Neurochem Res , vol.32 , pp. 1188-1195
    • Eren, I.1    Naziroglu, M.2    Demirdas, A.3
  • 12
    • 33746495629 scopus 로고    scopus 로고
    • Phosphodiesterase inhibitors: Effectiveness and new applications
    • van Driel M.F. Phosphodiesterase inhibitors: effectiveness and new applications Ned Tijdschr Geneeskd 150 2006 1613 1616
    • (2006) Ned Tijdschr Geneeskd , vol.150 , pp. 1613-1616
    • Van Driel, M.F.1
  • 13
    • 0036332629 scopus 로고    scopus 로고
    • Pharmacology of phosphodiesterase-5 inhibitors
    • Corbin J.D., and Francis S.H. Pharmacology of phosphodiesterase-5 inhibitors Int J Clin Pract 56 2002 453 459
    • (2002) Int J Clin Pract , vol.56 , pp. 453-459
    • Corbin, J.D.1    Francis, S.H.2
  • 14
    • 23244448247 scopus 로고    scopus 로고
    • Sildenafil inhibits the formation of superoxide and the expression of gp47 NAD[P]H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells
    • Koupparis A.J., Jeremy J.Y., and Muzaffar S. Sildenafil inhibits the formation of superoxide and the expression of gp47 NAD[P]H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells BJU Int 96 2005 423 427
    • (2005) BJU Int , vol.96 , pp. 423-427
    • Koupparis, A.J.1    Jeremy, J.Y.2    Muzaffar, S.3
  • 15
    • 0031403328 scopus 로고    scopus 로고
    • Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and AMP levels in the rabbit corpus cavernosum in vitro
    • Jeremy J.Y., Ballard S.A., and Naylor A.M. Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and AMP levels in the rabbit corpus cavernosum in vitro Br J Urol 79 1997 958 963
    • (1997) Br J Urol , vol.79 , pp. 958-963
    • Jeremy, J.Y.1    Ballard, S.A.2    Naylor, A.M.3
  • 16
    • 13844256288 scopus 로고    scopus 로고
    • Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: A human in vivo study
    • Gori T., Sicuro S., and Dragoni S. Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: a human in vivo study Circulation 111 2005 742 746
    • (2005) Circulation , vol.111 , pp. 742-746
    • Gori, T.1    Sicuro, S.2    Dragoni, S.3
  • 17
    • 55949122152 scopus 로고    scopus 로고
    • Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men
    • Perk H., Armagan A., and Naziroǧlu M. Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men J Clin Pharm Ther 33 2008 635 640
    • (2008) J Clin Pharm Ther , vol.33 , pp. 635-640
    • Perk, H.1    Armagan, A.2    Naziroǧlu, M.3
  • 18
    • 19344375531 scopus 로고    scopus 로고
    • Reduction of diabetes-induced oxidative stress by phosphodiesterase inhibitors in rats
    • Milani E., Nikfar S., and Khorasani R. Reduction of diabetes-induced oxidative stress by phosphodiesterase inhibitors in rats Comp Biochem and Physiol C Toxicol Pharmacol 140 2005 251 255
    • (2005) Comp Biochem and Physiol C Toxicol Pharmacol , vol.140 , pp. 251-255
    • Milani, E.1    Nikfar, S.2    Khorasani, R.3
  • 19
    • 0032538967 scopus 로고    scopus 로고
    • Cyclic nucleotides attenuate lipid peroxidation-mediated neuron toxicity
    • Keller J.N., Hanni K.B., and Mattson M.P. Cyclic nucleotides attenuate lipid peroxidation-mediated neuron toxicity Neuroreport 9 1998 3731 3734
    • (1998) Neuroreport , vol.9 , pp. 3731-3734
    • Keller, J.N.1    Hanni, K.B.2    Mattson, M.P.3
  • 20
    • 0035136155 scopus 로고    scopus 로고
    • Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices
    • Kohda Y., and Gemba M. Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices Jpn J Pharmacol 85 2001 54 59
    • (2001) Jpn J Pharmacol , vol.85 , pp. 54-59
    • Kohda, Y.1    Gemba, M.2
  • 21
    • 58749103648 scopus 로고    scopus 로고
    • Tadalafil improves short-term memory by suppressing ischemia-induced apoptosis of hippocampal neuronal cells in gerbils
    • Ko I.G., Shin M.S., and Kim B.K. Tadalafil improves short-term memory by suppressing ischemia-induced apoptosis of hippocampal neuronal cells in gerbils Pharmacol Biochem Behav 91 2009 629 635
    • (2009) Pharmacol Biochem Behav , vol.91 , pp. 629-635
    • Ko, I.G.1    Shin, M.S.2    Kim, B.K.3
  • 22
    • 78049458768 scopus 로고    scopus 로고
    • Sildenafil attenuates renal ischemia reperfusion injury by decreasing leukocyte infiltration
    • in press
    • Oruc O, Inc K, Aki FT, et al. Sildenafil attenuates renal ischemia reperfusion injury by decreasing leukocyte infiltration. Acta Histochem [in press].
    • Acta Histochem
    • Oruc, O.1    Inc, K.2    Aki, F.T.3
  • 23
    • 0036350615 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial KATP channels in rabbits
    • Ockaili R., Salloum F., and Hawkins J. Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial KATP channels in rabbits Am J Physiol Heart Circ Physiol 283 2002 263 269
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. 263-269
    • Ockaili, R.1    Salloum, F.2    Hawkins, J.3
  • 24
    • 75349103535 scopus 로고    scopus 로고
    • Protective effects of tadalafil on experimental spinal cord injury in rats
    • Serarslan Y., Yönden Z., and Ozgiray E. Protective effects of tadalafil on experimental spinal cord injury in rats J Clin Neurosci 17 2010 349 352
    • (2010) J Clin Neurosci , vol.17 , pp. 349-352
    • Serarslan, Y.1    Yönden, Z.2    Ozgiray, E.3
  • 25
    • 65049090531 scopus 로고    scopus 로고
    • The effects of sildenafil on the functional and structural changes of ileum induced by intestinal ischemia-reperfusion in rats
    • Soydan G., Sökmensüer C., and Kilinç K. The effects of sildenafil on the functional and structural changes of ileum induced by intestinal ischemia-reperfusion in rats Eur J Pharmacol 610 2009 87 92
    • (2009) Eur J Pharmacol , vol.610 , pp. 87-92
    • Soydan, G.1    Sökmensüer, C.2    Kilinç, K.3
  • 26
    • 42349097703 scopus 로고    scopus 로고
    • Protective effects of sildenafil administration on testicular torsion/detorsion damage in rats
    • Beheshtian A., Salmasi A.H., and Payabvash S. Protective effects of sildenafil administration on testicular torsion/detorsion damage in rats World J Urol 26 2008 197 202
    • (2008) World J Urol , vol.26 , pp. 197-202
    • Beheshtian, A.1    Salmasi, A.H.2    Payabvash, S.3
  • 27
    • 70649101493 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors facilitate noncontact erections in male rats: Site of action in the brain and mechanism of action
    • Sanna F., Succu S., and Boi A. Phosphodiesterase type 5 inhibitors facilitate noncontact erections in male rats: site of action in the brain and mechanism of action J Sex Med 6 2009 2680 2689
    • (2009) J Sex Med , vol.6 , pp. 2680-2689
    • Sanna, F.1    Succu, S.2    Boi, A.3
  • 28
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 95 1979 351 358
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 29
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • Lowry O.H., Rosebrough N.J., and Farr A. Protein measurement with the folin phenol reagent J Biol Chem 193 1951 265 275
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.3
  • 30
    • 0016335917 scopus 로고
    • Superoxide dismutase
    • Fridovich I. Superoxide dismutase Adv Enzymol 41 1974 35 97
    • (1974) Adv Enzymol , vol.41 , pp. 35-97
    • Fridovich, I.1
  • 32
    • 0029033537 scopus 로고
    • Nitrite and nitrate determinations in plasma: A critical evaluation
    • Moshage H., Kok B., and Huizenga J.R. Nitrite and nitrate determinations in plasma: a critical evaluation Clin Chem 41 1995 892 896
    • (1995) Clin Chem , vol.41 , pp. 892-896
    • Moshage, H.1    Kok, B.2    Huizenga, J.R.3
  • 33
    • 0025125066 scopus 로고
    • Determination of inorganic nitratein serum and urine by akinetic cadmium reduction method
    • Cortas N.K., and Wakid N.W. Determination of inorganic nitratein serum and urine by akinetic cadmium reduction method Clin Chem 36 1990 1440 1443
    • (1990) Clin Chem , vol.36 , pp. 1440-1443
    • Cortas, N.K.1    Wakid, N.W.2
  • 34
    • 0038353576 scopus 로고    scopus 로고
    • Efficacy of tadalafil for the treatment of erectile dysfunction at 24 and 36 hs after dosing: A randomized controlled trial
    • Porst H., Padma-Nathan H., and Giuliano F. Efficacy of tadalafil for the treatment of erectile dysfunction at 24 and 36 hs after dosing: a randomized controlled trial Urology 62 2003 121 125
    • (2003) Urology , vol.62 , pp. 121-125
    • Porst, H.1    Padma-Nathan, H.2    Giuliano, F.3
  • 35
    • 0142028778 scopus 로고    scopus 로고
    • Novel agents for sexual dysfunction
    • Hopps C.V., and Mulhall J.P. Novel agents for sexual dysfunction BJU Int 92 2003 534 538
    • (2003) BJU Int , vol.92 , pp. 534-538
    • Hopps, C.V.1    Mulhall, J.P.2
  • 36
    • 0141992796 scopus 로고    scopus 로고
    • The discovery of tadalafil: A novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino [1=,2=:1,6] pyrido[3,4-b] indole-1,4-dione analogues
    • Daugan A., Grondin P., and Ruault C. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino [1=,2=:1,6] pyrido[3,4-b] indole-1,4-dione analogues J Med Chem 46 2003 4533 4542
    • (2003) J Med Chem , vol.46 , pp. 4533-4542
    • Daugan, A.1    Grondin, P.2    Ruault, C.3
  • 37
    • 34247876061 scopus 로고    scopus 로고
    • The role of pharmacokinetics and pharmacodynamics in phosphodiesterase-5 inhibitor therapy
    • Mehrotra N., Gupta M., and Kovar A. The role of pharmacokinetics and pharmacodynamics in phosphodiesterase-5 inhibitor therapy Int J Impot Res 19 2007 253 264
    • (2007) Int J Impot Res , vol.19 , pp. 253-264
    • Mehrotra, N.1    Gupta, M.2    Kovar, A.3
  • 38
    • 44549085677 scopus 로고    scopus 로고
    • Molecular mechanisms of vitamin e on intracellular signaling pathways in brain
    • NazIroglu M. Molecular mechanisms of vitamin E on intracellular signaling pathways in brain L. Goth, Reactive oxygen species and diseases 2007 Research Signpost Press Kerala, India 239 256
    • (2007) Reactive Oxygen Species and Diseases , pp. 239-256
    • Naziroglu, M.1
  • 39
    • 0041926668 scopus 로고    scopus 로고
    • Reperfusion injury after detorsion of unilateral ovarian torsion in rabbits
    • Kaleli B., Aktan E., and Gezer S. Reperfusion injury after detorsion of unilateral ovarian torsion in rabbits Eur J Obstet Gynecol Reprod Biol 110 2003 99 101
    • (2003) Eur J Obstet Gynecol Reprod Biol , vol.110 , pp. 99-101
    • Kaleli, B.1    Aktan, E.2    Gezer, S.3
  • 40
    • 0021691159 scopus 로고
    • Oxygen free radical in ischemic acute renal failure in the rat
    • Paller M.S., Hoidal J.R., and Ferris T.F. Oxygen free radical in ischemic acute renal failure in the rat J Clin Invest 74 1984 1156 1164
    • (1984) J Clin Invest , vol.74 , pp. 1156-1164
    • Paller, M.S.1    Hoidal, J.R.2    Ferris, T.F.3
  • 41
    • 27744501977 scopus 로고    scopus 로고
    • Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells
    • Muzaffar S., Shukla N., and Srivastava A. Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells Br J Pharmacol 146 2005 109 117
    • (2005) Br J Pharmacol , vol.146 , pp. 109-117
    • Muzaffar, S.1    Shukla, N.2    Srivastava, A.3
  • 42
    • 0034053099 scopus 로고    scopus 로고
    • Pathophysiology of ischaemia-reperfusion injury
    • Carden D.L., and Granger D.N. Pathophysiology of ischaemia-reperfusion injury J Pathol 190 2000 255 266
    • (2000) J Pathol , vol.190 , pp. 255-266
    • Carden, D.L.1    Granger, D.N.2
  • 43
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • Wink D.A., and Mitchell J.B. Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide Free Radic Biol Med 25 1998 434 456
    • (1998) Free Radic Biol Med , vol.25 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 44
    • 0021218456 scopus 로고
    • Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species
    • Marklund S.L. Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species Biochem J 222 1984 649 655
    • (1984) Biochem J , vol.222 , pp. 649-655
    • Marklund, S.L.1
  • 45
    • 0033753223 scopus 로고    scopus 로고
    • Nitric oxide reactivity and mechanisms involved in its biological effects
    • Ortega Mateo A., and de Artinano A.A. Nitric oxide reactivity and mechanisms involved in its biological effects Pharmacol Res 42 2000 421 427
    • (2000) Pharmacol Res , vol.42 , pp. 421-427
    • Ortega Mateo, A.1    De Artinano, A.A.2
  • 46
    • 0037195723 scopus 로고    scopus 로고
    • Regulation of the brain's vascular responses to oxygen
    • Demchenko I.T., Oury T.D., and Crapo J.D. Regulation of the brain's vascular responses to oxygen Circulation Res 91 2002 1031 1037
    • (2002) Circulation Res , vol.91 , pp. 1031-1037
    • Demchenko, I.T.1    Oury, T.D.2    Crapo, J.D.3
  • 47
    • 0034099331 scopus 로고    scopus 로고
    • Platelets, oxidant stress and erectile dysfunction: An hypothesis
    • Jeremy J.Y., Angelini G.D., and Khan M. Platelets, oxidant stress and erectile dysfunction: an hypothesis Cardiovasc Res 46 2000 50 54
    • (2000) Cardiovasc Res , vol.46 , pp. 50-54
    • Jeremy, J.Y.1    Angelini, G.D.2    Khan, M.3
  • 49
    • 0242579616 scopus 로고    scopus 로고
    • Overview of phosphodiesterase 5 inhibition in erectile dysfunction
    • Rosen R.C., and Kostis J.B. Overview of phosphodiesterase 5 inhibition in erectile dysfunction Am J Cardiol 92 2003 9M 18M
    • (2003) Am J Cardiol , vol.92
    • Rosen, R.C.1    Kostis, J.B.2
  • 50
    • 4344677822 scopus 로고    scopus 로고
    • Nitroaspirins and morpholinosydnonimine, but not aspirin, inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells
    • Muzaffar S., Shukla N., and Angelini G.D. Nitroaspirins and morpholinosydnonimine, but not aspirin, inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells Circulation 110 2004 1140 1147
    • (2004) Circulation , vol.110 , pp. 1140-1147
    • Muzaffar, S.1    Shukla, N.2    Angelini, G.D.3
  • 51
    • 12344288164 scopus 로고    scopus 로고
    • Chronic treatment with tadalafil improves endothelial function in men with increased cardiovascular risk
    • Rosano G.M., Aversa A., and Vitale C. Chronic treatment with tadalafil improves endothelial function in men with increased cardiovascular risk Eur Urol 47 2005 214 222
    • (2005) Eur Urol , vol.47 , pp. 214-222
    • Rosano, G.M.1    Aversa, A.2    Vitale, C.3
  • 52
    • 29144450957 scopus 로고    scopus 로고
    • Effect of morphine on ischemia-reperfusion injury: Experimental study in testicular torsion rat model
    • Salmasi A.H., Beheshtian A., and Payabvash S. Effect of morphine on ischemia-reperfusion injury: experimental study in testicular torsion rat model Urology 66 2005 1338 1342
    • (2005) Urology , vol.66 , pp. 1338-1342
    • Salmasi, A.H.1    Beheshtian, A.2    Payabvash, S.3


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