Liquid chromatography/tandem mass spectrometry assay for the simultaneous determination of cefoperazone and sulbactam in plasma and its application to a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 30, 2010, Pages 3119-3124

  Zhou, Yingjie ^a   Zhang, Jing ^a   Guo, Beining ^a   Yu, Jicheng ^a   Shi, Yaoguo ^a   Wang, Minggui ^a   Zhang, Yingyuan ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Cefoperazone; Human plasma; LC MS MS; Method validation; Pharmacokinetic study; Sulbactam

Indexed keywords

CEFOPERAZONE; HUMAN PLASMAS; LC-MS/MS; METHOD VALIDATIONS; PHARMACOKINETIC STUDY; SULBACTAM;

ELECTROSPRAY IONIZATION; ESTERS; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS; PULMONARY DISEASES; SOLVENT EXTRACTION;

LIQUID CHROMATOGRAPHY;

CEFOPERAZONE; CEFUROXIME; SULBACTAM; SULPERAZON;

ACCURACY; ARTICLE; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PNEUMONIA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANTI-BACTERIAL AGENTS; CEFOPERAZONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMBINATIONS; HUMANS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULBACTAM; TANDEM MASS SPECTROMETRY;

EID: 78049472222     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.09.021     Document Type: Article

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