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Volumn 16, Issue 3, 2010, Pages 121-128

Tissue-selective agents: Selective estrogen receptor modulators and the tissue-selective estrogen complex

Author keywords

Estrogen; Menopause; Selective estrogen receptor modulator; Tissue selective estrogen complex

Indexed keywords

BAZEDOXIFENE; CENTCHROMAN; CLOMIFENE; CONJUGATED ESTROGEN; ESTROGEN DERIVATIVE; LASOFOXIFENE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TISSUE SELECTIVE ESTROGEN COMPLEX; TOREMIFENE; UNCLASSIFIED DRUG;

EID: 78049468658     PISSN: 13621807     EISSN: 17404568     Source Type: Journal    
DOI: 10.1258/mi.2010.010033     Document Type: Review
Times cited : (20)

References (43)
  • 1
    • 33846418467 scopus 로고    scopus 로고
    • See (last accessed 6 June 2010)
    • US Census Bureau. Midyear population, by age and sex. See http://www.census.gov/ipc/www/idb/region.php (last accessed 6 June 2010)
    • Midyear Population, by Age and Sex
  • 2
    • 78049390040 scopus 로고    scopus 로고
    • See (last accessed 9 June 2010)
    • UK National Statistics. 2008-based national population projections. See www.statistics.gov.uk/downloads/theme-population/NPP2008/NatPopProj2008.pdf (last accessed 9 June 2010)
    • 2008-based National Population Projections
  • 4
    • 0022118629 scopus 로고
    • The prevalence of hot flash and associated variables among perimenopausal women
    • Feldman BM, Voda A, Gronseth E. The prevalence of hot flash and associated variables among perimenopausal women. Res Nur Health 1985;8:261-8
    • (1985) Res Nur Health , vol.8 , pp. 261-268
    • Feldman, B.M.1    Voda, A.2    Gronseth, E.3
  • 6
    • 57849153536 scopus 로고    scopus 로고
    • A new approach to menopausal therapy: The tissue selective estrogen complex
    • Komm BS. A new approach to menopausal therapy: the tissue selective estrogen complex. Reprod Sci 2008;15:984-92
    • (2008) Reprod Sci , vol.15 , pp. 984-992
    • Komm, B.S.1
  • 7
    • 0025121447 scopus 로고
    • Hot flashes: Epidemiology and physiology
    • Kronenberg F. Hot flashes: epidemiology and physiology. Ann N Y Acad Sci 1990;592:52-86
    • (1990) Ann N Y Acad Sci , vol.592 , pp. 52-86
    • Kronenberg, F.1
  • 8
    • 67649890139 scopus 로고    scopus 로고
    • Duration of vasomotor symptoms in middle-aged women: A longitudinal study
    • Col NF, Guthrie JR, Politi M, et al. Duration of vasomotor symptoms in middle-aged women: a longitudinal study. Menopause 2009;16:453-7
    • (2009) Menopause , vol.16 , pp. 453-457
    • Col, N.F.1    Guthrie, J.R.2    Politi, M.3
  • 10
    • 0034955472 scopus 로고    scopus 로고
    • Endometrial effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate
    • DOI 10.1016/S0015-0282(01)01828-3, PII S0015028201018283
    • Pickar JH, Yeh I, Wheeler JE, et al. Endometrial effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate. Fertil Steril 2001;76:25-31 (Pubitemid 32600955)
    • (2001) Fertility and Sterility , vol.76 , Issue.1 , pp. 25-31
    • Pickar, J.H.1    Yeh, I.-T.2    Wheeler, J.E.3    Cunnane, M.F.4    Speroff, L.5
  • 11
    • 0242661467 scopus 로고    scopus 로고
    • Endometrial effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate: Two-year substudy results
    • Pickar JH, Yeh IT, Wheeler JE, et al. Endometrial effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate: two-year substudy results. Fertil Steril 2003;80:1234-40
    • (2003) Fertil Steril , vol.80 , pp. 1234-1240
    • Pickar, J.H.1    Yeh, I.T.2    Wheeler, J.E.3
  • 12
    • 0029809730 scopus 로고    scopus 로고
    • Cancer incidence and mortality in women receiving estrogen and estrogen- Progestin replacement therapy - Long-term follow-up of a Swedish cohort
    • DOI 10.1002/(SICI)1097-0215(19960729)67:3<327::AID-IJC4>3.3.CO;2-J
    • Persson I, Yuen J, Bergkvist L, et al. Cancer incidence and mortality in women receiving estrogen and estrogen-progestin replacement therapy - long-term follow-up of a Swedish cohort. Int J Cancer 1996;67:327-32 (Pubitemid 26274121)
    • (1996) International Journal of Cancer , vol.67 , Issue.3 , pp. 327-332
    • Persson, I.1    Yuen, J.2    Bergkvist, L.3    Schairer, C.4
  • 13
    • 77954169894 scopus 로고    scopus 로고
    • Tissue-selective estrogen complexes: A promising option for the comprehensive management of menopausal symptoms
    • Archer DF. Tissue-selective estrogen complexes: a promising option for the comprehensive management of menopausal symptoms. Drugs Aging 2010;27:533-44
    • (2010) Drugs Aging , vol.27 , pp. 533-544
    • Archer, D.F.1
  • 14
    • 77956652851 scopus 로고    scopus 로고
    • SERMs: Progress and future perspectives
    • Pickar JH, MacNeil T, Ohleth K. SERMs: Progress and future perspectives. Maturitas 2010;67:129-38
    • (2010) Maturitas , vol.67 , pp. 129-138
    • Pickar, J.H.1    MacNeil, T.2    Ohleth, K.3
  • 15
    • 58149218461 scopus 로고    scopus 로고
    • Differential biochemical and cellular actions of premarin estrogens: Distinct pharmacology of bazedoxifene-conjugated estrogens combination
    • Berrodin TJ, Chang KC, Komm BS, et al. Differential biochemical and cellular actions of premarin estrogens: distinct pharmacology of bazedoxifene-conjugated estrogens combination. Mol Endocrinol 2009;23:74-85
    • (2009) Mol Endocrinol , vol.23 , pp. 74-85
    • Berrodin, T.J.1    Chang, K.C.2    Komm, B.S.3
  • 17
    • 56549102911 scopus 로고    scopus 로고
    • The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention
    • Kharode Y, Bodine PVN, Miller CP, et al. The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention. Endocrinology 2008;149:6084-91
    • (2008) Endocrinology , vol.149 , pp. 6084-6091
    • Kharode, Y.1    Bodine, P.V.N.2    Miller, C.P.3
  • 19
    • 0015069359 scopus 로고
    • A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474
    • Cole MP, Jones CT, Todd ID. A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474. Br J Cancer 1971;25:270-5
    • (1971) Br J Cancer , vol.25 , pp. 270-275
    • Cole, M.P.1    Jones, C.T.2    Todd, I.D.3
  • 20
    • 0026585852 scopus 로고
    • Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer
    • Love RR, Mazess RB, Barden HS, et al. Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer. N Engl J Med 1992;326:852-6
    • (1992) N Engl J Med , vol.326 , pp. 852-856
    • Love, R.R.1    Mazess, R.B.2    Barden, H.S.3
  • 21
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • DOI 10.1016/S0092-8674(00)81717-1
    • Shiau AK, Barstad D, Loria PM, et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998;95:927-37 (Pubitemid 29019045)
    • (1998) Cell , vol.95 , Issue.7 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 22
    • 58149161856 scopus 로고    scopus 로고
    • Molecular mechanisms of endocrine resistance and their implications in the therapy of breast cancer
    • Zilli M, Grassadonia A, Tinari N, et al. Molecular mechanisms of endocrine resistance and their implications in the therapy of breast cancer. Biochim Biophys Acta 2009;1795:62-81
    • (2009) Biochim Biophys Acta , vol.1795 , pp. 62-81
    • Zilli, M.1    Grassadonia, A.2    Tinari, N.3
  • 28
    • 72649104020 scopus 로고    scopus 로고
    • Gene expression profiling studies of three SERMs and their conjugated estrogen combinations in human breast cancer cells: Insights into the unique antagonistic effects of bazedoxifene on conjugated estrogens
    • Chang KC, Wang Y, Bodine PV, et al. Gene expression profiling studies of three SERMs and their conjugated estrogen combinations in human breast cancer cells: insights into the unique antagonistic effects of bazedoxifene on conjugated estrogens. J Steroid Biochem Mol Biol 2010;118:117-24
    • (2010) J Steroid Biochem Mol Biol , vol.118 , pp. 117-124
    • Chang, K.C.1    Wang, Y.2    Bodine, P.V.3
  • 29
    • 0035686794 scopus 로고    scopus 로고
    • Developing a SERM: Stringent preclinical selection criteria leading to an acceptable candidate (WAY-140424) for clinical evaluation
    • Komm BS, Lyttle CR. Developing a SERM: stringent preclinical selection criteria leading to an acceptable candidate (WAY-140424) for clinical evaluation. Ann N Y Acad Sci 2001;949:317-26
    • (2001) Ann N Y Acad Sci , vol.949 , pp. 317-326
    • Komm, B.S.1    Lyttle, C.R.2
  • 30
    • 23844531615 scopus 로고    scopus 로고
    • Bazedoxifene acetate: A selective estrogen receptor modulator with improved selectivity
    • DOI 10.1210/en.2005-0030
    • Komm BS, Kharode YP, Bodine PV, et al. Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology 2005;146:3999-4008 (Pubitemid 41175771)
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3999-4008
    • Komm, B.S.1    Kharode, Y.P.2    Bodine, P.V.N.3    Harris, H.A.4    Miller, C.P.5    Lyttle, C.R.6
  • 31
    • 43549101923 scopus 로고    scopus 로고
    • Activity of three selective estrogen receptor modulators on hormone-dependent responses in the mouse uterus and mammary gland
    • Crabtree JS, Peano BJ, Zhang X, et al. Activity of three selective estrogen receptor modulators on hormone-dependent responses in the mouse uterus and mammary gland. Mol Cell Endocrinol 2008;287:40-6
    • (2008) Mol Cell Endocrinol , vol.287 , pp. 40-46
    • Crabtree, J.S.1    Peano, B.J.2    Zhang, X.3
  • 32
    • 63849224133 scopus 로고    scopus 로고
    • Effects of various selective estrogen receptor modulators with or without conjugated estrogens on mouse mammary gland
    • Peano BJ, Crabtree JS, Komm BS, et al. Effects of various selective estrogen receptor modulators with or without conjugated estrogens on mouse mammary gland. Endocrinology 2009;150:1897-903
    • (2009) Endocrinology , vol.150 , pp. 1897-1903
    • Peano, B.J.1    Crabtree, J.S.2    Komm, B.S.3
  • 33
    • 69049085452 scopus 로고    scopus 로고
    • Endometrial effects of a tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens as a menopausal therapy
    • Pickar JH, Yeh I-T, Bachmann G, et al. Endometrial effects of a tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens as a menopausal therapy. Fertil Steril 2009;92:1018-24
    • (2009) Fertil Steril , vol.92 , pp. 1018-1024
    • Pickar, J.H.1    Yeh, I.-T.2    Bachmann, G.3
  • 34
    • 69049120132 scopus 로고    scopus 로고
    • Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic bone parameters and overall safety profile
    • Lobo RA, Pinkerton JV, Gass MLS, et al. Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic bone parameters and overall safety profile. Fertil Steril 2009;92:1025-38
    • (2009) Fertil Steril , vol.92 , pp. 1025-1038
    • Lobo, R.A.1    Pinkerton, J.V.2    Gass, M.L.S.3
  • 35
    • 69049083661 scopus 로고    scopus 로고
    • Efficacy of tissue-selective estrogen complex (TSEC) of bazedoxifene/conjugated estrogens (BZA/CE) for osteoporosis prevention in at-risk postmenopausal women
    • Lindsay R, Gallagher JC, Kagan R, et al. Efficacy of tissue-selective estrogen complex (TSEC) of bazedoxifene/conjugated estrogens (BZA/CE) for osteoporosis prevention in at-risk postmenopausal women. Fertil Steril 2009;92:1045-52
    • (2009) Fertil Steril , vol.92 , pp. 1045-1052
    • Lindsay, R.1    Gallagher, J.C.2    Kagan, R.3
  • 36
    • 69049112720 scopus 로고    scopus 로고
    • Bazedoxifene/conjugated estrogens (BZA/CE): Incidence of uterine bleeding in postmenopausal women
    • Archer DF, Lewis V, Carr BR, et al. Bazedoxifene/conjugated estrogens (BZA/CE): incidence of uterine bleeding in postmenopausal women. Fertil Steril 2009;92:1039-44
    • (2009) Fertil Steril , vol.92 , pp. 1039-1044
    • Archer, D.F.1    Lewis, V.2    Carr, B.R.3
  • 37
    • 68349129906 scopus 로고    scopus 로고
    • Relief of vasomotor symptoms with the tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens: A randomized, controlled trial
    • Pinkerton JV, Utian WH, Constantine GD, et al. Relief of vasomotor symptoms with the tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens: a randomized, controlled trial. Menopause 2009;16:1116-24
    • (2009) Menopause , vol.16 , pp. 1116-1124
    • Pinkerton, J.V.1    Utian, W.H.2    Constantine, G.D.3
  • 40
    • 0034992740 scopus 로고    scopus 로고
    • Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on endometrial bleeding
    • DOI 10.1016/S0015-0282(01)01792-7, PII S0015028201017927
    • Archer DF, Dorin M, Lewis V, et al. Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on endometrial bleeding. Fertil Steril 2001;75:1080-7 (Pubitemid 32522601)
    • (2001) Fertility and Sterility , vol.75 , Issue.6 , pp. 1080-1087
    • Archer, D.F.1    Dorin, M.2    Lewis, V.3    Schneider, D.L.4    Pickar, J.H.5
  • 41
    • 34447266932 scopus 로고    scopus 로고
    • The effects of combined raloxifene and oral estrogen on vasomotor symptoms and endometrial safety
    • Stovall DW, Utian W, Gass M, et al. The effects of combined raloxifene and oral estrogen on vasomotor symptoms and endometrial safety. Menopause 2007;14:510-17
    • (2007) Menopause , vol.14 , pp. 510-517
    • Stovall, D.W.1    Utian, W.2    Gass, M.3
  • 42
    • 2342545489 scopus 로고    scopus 로고
    • Transition from estrogen therapy to raloxifene in postmenopausal women: Effects on treatment satisfaction and the endometrium - A pilot study
    • DOI 10.1097/01.GME.0000087981.28957.CF
    • Davis SR, O'Neill SM, Eden J, et al. Transition from estrogen therapy to raloxifene in postmenopausal women: effects on treatment satisfaction and the endometrium-a pilot study. Menopause 2004;11:167-75 (Pubitemid 40353234)
    • (2004) Menopause , vol.11 , Issue.2 , pp. 167-175
    • Davis, S.R.1    O'Neill, S.M.2    Eden, J.3    Baber, R.4    Ekangaki, A.5    Stocks, J.M.6    Thiebaud, D.7
  • 43
    • 42949129523 scopus 로고    scopus 로고
    • Climacteric symptom control after the addition of low-dose esterified conjugated estrogens to raloxifene standard doses
    • Carranza-Lira S, Gooch AL, Saldivar N, et al. Climacteric symptom control after the addition of low-dose esterified conjugated estrogens to raloxifene standard doses. Int J Fertil Womens Med 2007;52:93-6
    • (2007) Int J Fertil Womens Med , vol.52 , pp. 93-96
    • Carranza-Lira, S.1    Gooch, A.L.2    Saldivar, N.3


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