Selective substitution of amino acids limits proteolytic cleavage and improves the bioactivity of an anti-biofilm peptide that targets the periodontal pathogen, Porphyromonas gingivalis

Peptides

Volumn 31, Issue 12, 2010, Pages 2173-2178

  Daep, Carlo Amorin ^a   Novak, Elizabeth A ^a   Lamont, Richard J ^b   Demuth, Donald R ^a  

^a UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Biofilm; Gingipain; Porphyromonas gingivalis; Streptococcus gordonii

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL ENZYME; BACTERIAL PROTEIN; CLINDAMYCIN; CYSTEINE PROTEINASE; ERYTHROMYCIN; GINGIPAIN R; LYSINE; TETRACYCLINE;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL CELL; BACTERIUM ADHERENCE; BINDING AFFINITY; BIOFILM; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INACTIVATION; MOUTH CAVITY; NONHUMAN; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; STREPTOCOCCUS GORDONII;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOFILMS; DRUG STABILITY; ENZYME ACTIVATION; HUMANS; PEPTIDE HYDROLASES; PEPTIDES; PORPHYROMONAS GINGIVALIS; SALIVA; STREPTOCOCCUS;

PORPHYROMONAS GINGIVALIS; STREPTOCOCCUS GORDONII;

EID: 78049467540     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.08.014     Document Type: Article

References (44)

1. J. Aduse-Opoku, N.N. Davies, A. Gallagher, A. Hashim, H.E. Evans, and M. Rangarajan Generation of lys-gingipain protease activity in Porphyromonas gingivalis W50 is independent of Arg-gingipain protease activities Microbiology 146 Pt 8 2000 1933 1940
2. D.J. Bradshaw, P.D. Marsh, G.K. Watson, and C. Allison Role of Fusobacterium nucleatum and coaggregation in anaerobe survival in planktonic and biofilm oral microbial communities during aeration Infect Immun 66 1998 4729 4732
3. W. Brooks, D.R. Demuth, S. Gil, and R.J. Lamont Identification of a Streptococcus gordonii SspB domain that mediates adhesion to Porphyromonas gingivalis Infect Immun 65 1997 3753 3758
4. W.O. Chung, D.R. Demuth, and R.J. Lamont Identification of a Porphyromonas gingivalis receptor for the Streptococcus gordonii SspB protein Infect Immun 68 2000 6758 6762
5. G.S. Cook, J.W. Costerton, and R.J. Lamont Biofilm formation by Porphyromonas gingivalis and Streptococcus gordonii J Periodontal Res 33 1998 323 327
6. M.A. Curtis, H.K. Kuramitsu, M. Lantz, F.L. Macrina, K. Nakayama, and J. Potempa Molecular genetics and nomenclature of proteases of Porphyromonas gingivalis J Periodontal Res 34 1999 464 472
7. C.A. Daep, D.M. James, R.J. Lamont, and D.R. Demuth Structural characterization of peptide-mediated inhibition of Porphyromonas gingivalis biofilm formation Infect Immun 74 2006 5756 5762
8. C.A. Daep, R.J. Lamont, and D.R. Demuth Interaction of Porphyromonas gingivalis with oral streptococci requires a motif that resembles the eukaryotic nuclear receptor box protein-protein interaction domain Infect Immun 76 2008 3273 3280
9. R.T. Demmer, and M. Desvarieux Periodontal infections and cardiovascular disease: the heart of the matter J Am Dent Assoc 137 Suppl. 2006 14S 20S
10. D.R. Demuth, D.C. Irvine, J.W. Costerton, G.S. Cook, and R.J. Lamont Discrete protein determinant directs the species-specific adherence of Porphyromonas gingivalis to oral streptococci Infect Immun 69 2001 5736 5741
11. T. Dietrich, and R.I. Garcia Associations between periodontal disease and systemic disease: evaluating the strength of the evidence J Periodontol 76 2005 2175 2184
12. D. Grenier Demonstration of a bimodal coaggregation reaction between Porphyromonas gingivalis and Treponema denticola Oral Microbiol Immunol 7 1992 280 284
13. D. Grenier, S. Imbeault, P. Plamondon, G. Grenier, K. Nakayama, and D. Mayrand Role of gingipains in growth of Porphyromonas gingivalis in the presence of human serum albumin Infect Immun 69 2001 5166 5172
14. D. Grenier, S. Roy, F. Chandad, P. Plamondon, M. Yoshioka, and K. Nakayama Effect of inactivation of the Arg- and/or Lys-gingipain gene on selected virulence and physiological properties of Porphyromonas gingivalis Infect Immun 71 2003 4742 4748
15. S.C. Holt, J. Ebersole, J. Felton, M. Brunsvold, and K.S. Kornman Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis Science 239 1988 55 57
16. S.C. Holt, L. Kesavalu, S. Walker, and C.A. Genco Virulence factors of Porphyromonas gingivalis Periodontology 20 2000 168 238
17. H.F. Jenkinson, and D.R. Demuth Structure, function and immunogenicity of streptococcal antigen I/II polypeptides Mol Microbiol 23 1997 183 190
18. S.A. Kinder, and S.C. Holt Characterization of coaggregation between Bacteroides gingivalis T22 and Fusobacterium nucleatum T18 Infect Immun 57 1989 3425 3433
19. P.E. Kolenbrander, and R.N. Andersen Inhibition of coaggregation between Fusobacterium nucleatum and Porphyromonas (Bacteroides) gingivalis by lactose and related sugars Infect Immun 57 1989 3204 3209
20. H.K. Kuramitsu Proteases of Porphyromonas gingivalis: what don't they do? Oral Microbiol Immunol 13 1998 263 270
21. R.J. Lamont, C.A. Bevan, S. Gil, R.E. Persson, and B. Rosan Involvement of Porphyromonas gingivalis fimbriae in adherence to Streptococcus gordonii Oral Microbiol Immunol 8 1993 272 276
22. R.J. Lamont, A. El-Sabaeny, Y. Park, G.S. Cook, J.W. Costerton, and D.R. Demuth Role of the Streptococcus gordonii SspB protein in the development of Porphyromonas gingivalis biofilms on streptococcal substrates Microbiology 148 2002 1627 1636
23. R.J. Lamont, S. Gil, D.R. Demuth, D. Malamud, and B. Rosan Molecules of Streptococcus gordonii that bind to Porphyromonas gingivalis Microbiology 140 Pt 4 1994 867 872
24. R.J. Lamont, S.G. Hersey, and B. Rosan Characterization of the adherence of Porphyromonas gingivalis to oral streptococci Oral Microbiol Immunol 7 1992 193 197
25. R.J. Lamont, and H.F. Jenkinson Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis Microbiol Mol Biol Rev 62 1998 1244 1263
26. J.K. Ma, C.G. Kelly, G. Munro, R.A. Whiley, and T. Lehner Conservation of the gene encoding streptococcal antigen I/II in oral streptococci Infect Immun 59 1991 2686 2694
27. K. Maeda, H. Nagata, Y. Yamamoto, M. Tanaka, J. Tanaka, and N. Minamino Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus oralis functions as a coadhesin for Porphyromonas gingivalis major fimbriae Infect Immun 72 2004 1341 1348
28. D. Mayrand, and S.C. Holt Biology of asaccharolytic black-pigmented Bacteroides species Microbiol Rev 52 1988 134 152
29. J. Mikolajczyk-Pawlinska, T. Kordula, N. Pavloff, P.A. Pemberton, W.C. Chen, and J. Travis Genetic variation of Porphyromonas gingivalis genes encoding gingipains, cysteine proteinases with arginine or lysine specificity Biol Chem 379 1998 205 211
30. K.E. Nelson, R.D. Fleischmann, R.T. DeBoy, I.T. Paulsen, D.E. Fouts, and J.A. Eisen Complete genome sequence of the oral pathogenic Bacterium Porphyromonas gingivalis strain W83 J Bacteriol 185 2003 5591 5601
31. L. Nibali, F. D'Aiuto, G. Griffiths, K. Patel, J. Suvan, and M.S. Tonetti Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control study J Clin Periodontol 34 2007 931 937
32. O.B.-S. NM, P.D. Veith, S.G. Dashper, and E.C. Reynolds Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire Curr Protein Pept Sci 4 2003 409 426
33. K. Okuda, R. Kimizuka, S. Abe, T. Kato, and K. Ishihara Involvement of periodontopathic anaerobes in aspiration pneumonia J Periodontol 76 2005 2154 2160
34. S. Paju, and F.A. Scannapieco Oral biofilms, periodontitis, and pulmonary infections Oral Dis 13 2007 508 512
35. Y. Park, M.R. Simionato, K. Sekiya, Y. Murakami, D. James, and W. Chen Short fimbriae of Porphyromonas gingivalis and their role in coadhesion with Streptococcus gordonii Infect Immun 73 2005 3983 3989
36. R. Pike, W. McGraw, J. Potempa, and J. Travis Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins J Biol Chem 269 1994 406 411
37. J. Potempa, R. Pike, and J. Travis Titration and mapping of the active site of cysteine proteinases from Porphyromonas gingivalis (gingipains) using peptidyl chloromethanes Biol Chem 378 1997 223 230
38. S.V. Seddon, H.N. Shah, J.M. Hardie, and J.P. Robinson Chemically defined and minimal media for Bacteroides gingivalis Curr Microbiol 17 1988 147 149
39. H.N.W.R. Shah Catabolism of aspartate and asparagine by Bacteroides intermedius and Bacteroides gingivalis Curr Microbiol 15 1987 313 318
40. H.N.W.R. Shah Utilization of glucose and amino acids by Bacteroides intermedius and Bacteroides gingivalis Curr Microbiol 15 1987 241 246
41. M.W. Stinson, K. Safulko, and M.J. Levine Adherence of Porphyromonas (Bacteroides) gingivalis to Streptococcus sanguis in vitro Infect Immun 59 1991 102 108
42. N. Takahashi, T. Sato, and T. Yamada Metabolic pathways for cytotoxic end product formation from glutamate- and aspartate-containing peptides by Porphyromonas gingivalis J Bacteriol 182 2000 4704 4710
43. R. Thorman, M. Neovius, and B. Hylander Clinical findings in oral health during progression of chronic kidney disease to end-stage renal disease in a Swedish population Scand J Urol Nephrol 43 2009 154 159
44. T. Yamaguchi, K. Kasamo, M. Chuman, M. Machigashira, M. Inoue, and T. Sueda Preparation and characterization of an Actinomyces naeslundii aggregation factor that mediates coaggregation with Porphyromonas gingivalis J Periodontal Res 33 1998 460 468