메뉴 건너뛰기




Volumn 48, Issue 10, 2010, Pages 1043-1052

Co-polymeric hydrophilic nanospheres for drug delivery: Release kinetics, and cellular uptake

Author keywords

Co polymeric nanospheres; Cytotoxicity; Hexyl carbamoyl fluorouracil (HCFU); Mia paca 3 human pancreatic cell line

Indexed keywords

1-HEXYLCARBAMOYL-5-FLUOROURACIL; ACRYLAMIDE DERIVATIVE; ANTINEOPLASTIC AGENT; CARMOFUR; DRUG CARRIER; DRUG DERIVATIVE; FLUOROURACIL; N ISOPROPYLACRYLAMIDE; N-ISOPROPYLACRYLAMIDE; NANOSPHERE; POLYMER; POVIDONE;

EID: 78049462899     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (28)
  • 2
    • 0019848930 scopus 로고
    • Present and future applications of biomaterials in controlled drug delivery systems
    • Langer R S & Peppas NA, Present and future applications of biomaterials in controlled drug delivery systems. Biomaterials, 2 (1981) 201.
    • (1981) Biomaterials , vol.2 , pp. 201
    • Langer, R.S.1    Peppas, N.A.2
  • 3
    • 0032021401 scopus 로고    scopus 로고
    • Immobilization of α-chymotrypsin in thermally reversible isopropylacrylamide copolymer gel
    • Cicek H & Tuncel A, Immobilization of α-chymotrypsin in thermally reversible isopropylacrylamide copolymer gel, J Polym Sci, Part A Polym Chem, 36 (1998) 543.
    • (1998) J Polym Sci, Part a Polym Chem , vol.36 , pp. 543
    • Cicek, H.1    Tuncel, A.2
  • 4
    • 0022858683 scopus 로고
    • A new concept for macro- molecular therapetics in cancer chemotherapy: Mechanisms of tumorotropic accumulation of proteins and the anti-tumor agent SMANCS
    • Matsamura Y & Maeda H, A new concept for macro- molecular therapetics in cancer chemotherapy: mechanisms of tumorotropic accumulation of proteins and the anti-tumor agent SMANCS, Cancer Res, 46 (1986) 6387.
    • (1986) Cancer Res , vol.46 , pp. 6387
    • Matsamura, Y.1    Maeda, H.2
  • 5
    • 0030988750 scopus 로고    scopus 로고
    • Biomedical applications of nano-technology- implications for drug targeting and gene therapy
    • Davis S S, Biomedical applications of nano-technology- implications for drug targeting and gene therapy, TIBTEC, 15 (1997) 217.
    • (1997) TIBTEC , vol.15 , pp. 217
    • Davis, S.S.1
  • 6
    • 0024357420 scopus 로고
    • Fluorouracil, doxorubicin, cisplatin and altretamine in the treatment of metastatic carcinoma of unknown primary
    • Becouarn Y, Brunet R. & Barbe-Gaston C, Fluorouracil, doxorubicin, cisplatin and altretamine in the treatment of metastatic carcinoma of unknown primary, Eur. J. Cancer Clin. Oncol, 25 (1989) 861.
    • (1989) Eur. J. Cancer Clin. Oncol , vol.25 , pp. 861
    • Becouarn, Y.1    Brunet, R.2    Barbe-Gaston, C.3
  • 8
    • 78049477415 scopus 로고
    • A less toxic fluorouracil dosage schedule
    • Ansfield F J A less toxic fluorouracil dosage schedule, J Am Med Assoc, 190 (1964) 686.
    • (1964) J Am Med Assoc , vol.190 , pp. 686
    • Ansfield, F.J.1
  • 9
    • 0015144857 scopus 로고
    • 5-Fluorouracil given once weekly; Comparison of intravenous and oral administration
    • Bateman J R, Pugh P R, Cassidy F R, Marshall G J & Irwin L E, 5-Fluorouracil given once weekly; Comparison of intravenous and oral administration, Cancer, 28 (1971) 907.
    • (1971) Cancer , vol.28 , pp. 907
    • Bateman, J.R.1    Pugh, P.R.2    Cassidy, F.R.3    Marshall, G.J.4    Irwin, L.E.5
  • 10
    • 0015968140 scopus 로고
    • The administration of 5-Fluorauracil by mouth
    • Bruckner H W & Creasy W A, The administration of 5-Fluorauracil by mouth, Cancer, 33 (1974) 14.
    • (1974) Cancer , vol.33 , pp. 14
    • Bruckner, H.W.1    Creasy, W.A.2
  • 12
    • 0015935117 scopus 로고
    • 5-Fluorouracil in the treatment of gastrointestinal neoplasia
    • Kaufman S,5-Fluorouracil in the treatment of gastrointestinal neoplasia, New England J Med, 288 (1973) 199.
    • (1973) New England J Med , vol.288 , pp. 199
    • Kaufman, S.1
  • 13
    • 0017748830 scopus 로고
    • Pharmacokinetics of 5-Fluorouracil: Inter-relationship with Biochemical kinetics in Monitoring Therapy
    • Sadee W & Wong C G, Pharmacokinetics of 5-Fluorouracil: Inter-relationship with Biochemical kinetics in Monitoring Therapy, Clinical Pharmacokinetics, 2 (1977) 437.
    • (1977) Clinical Pharmacokinetics , vol.2 , pp. 437
    • Sadee, W.1    Wong, C.G.2
  • 15
    • 0028109447 scopus 로고
    • A simple microassay for computing the Haemolytic potency of the drugs
    • Raghava G P S, Goel A, Singh M A & Varshney G C, A simple microassay for computing the Haemolytic potency of the drugs, Biotechniques, 17 (1994) 1148.
    • (1994) Biotechniques , vol.17 , pp. 1148
    • Raghava, G.P.S.1    Goel, A.2    Singh, M.A.3    Varshney, G.C.4
  • 16
    • 0021061819 scopus 로고
    • Rapid Calorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
    • Mosmann T, Rapid Calorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay, J Immunol Meth, 65 (1983) 55.
    • (1983) J Immunol Meth , vol.65 , pp. 55
    • Mosmann, T.1
  • 17
    • 18344382928 scopus 로고    scopus 로고
    • Release kinetics from bio-polymeric nanoparticles encapsulating protein synthesis inhibitor-cycloheximide, for possible therapeutic applications
    • Verma A K, Sachin K, Saxena A & Bohidar H B, Release kinetics from bio-polymeric nanoparticles encapsulating protein synthesis inhibitor-cycloheximide, for possible therapeutic applications, Curr Pharm Biotechnol, 6 (2005) 121.
    • (2005) Curr Pharm Biotechnol , vol.6 , pp. 121
    • Verma, A.K.1    Sachin, K.2    Saxena, A.3    Bohidar, H.B.4
  • 18
    • 0034687580 scopus 로고    scopus 로고
    • Ketorolac entrappedinpolymericmicelles:Preparation, characterization and ocular anti-inflammatory studies
    • Gupta A K, Madan S, Majumdar D K & Maitra A, Ketorolac entrappedin polymericmicelles:preparation, characterization and ocular anti-inflammatory studies, Int J Pharm, 209 (2001) 1.
    • (2001) Int J Pharm , vol.209 , pp. 1
    • Gupta, A.K.1    Madan, S.2    Majumdar, D.K.3    Maitra, A.4
  • 19
    • 0037123739 scopus 로고    scopus 로고
    • Synthesis and release of 5-FU from poly (N-vinylpyrrolidinone) bearing 5-FU derivatives
    • Liu Z & Rimmer S, Synthesis and release of 5-FU from poly (N-vinylpyrrolidinone) bearing 5-FU derivatives, J Contro Rel, 81 (2002) 91.
    • (2002) J Contro Rel , vol.81 , pp. 91
    • Liu, Z.1    Rimmer, S.2
  • 21
    • 0033178588 scopus 로고    scopus 로고
    • Smart polymers and what they could do in biotechnology and medicine
    • Galaev I Y & Mattiasson B, Smart polymers and what they could do in biotechnology and medicine, Trends Biotechnol, 17 (1999) 335.
    • (1999) Trends Biotechnol , vol.17 , pp. 335
    • Galaev, I.Y.1    Mattiasson, B.2
  • 22
    • 0004700019 scopus 로고
    • Prodrugs of 5-FU II: Hydrolysis Kinetics bio activation, solubility and lipophilicity of N-alkoxycarbomyl derivatives of 5-FU
    • Burr A & Bundgaard H, Prodrugs of 5-FU II: Hydrolysis Kinetics bio activation, solubility and lipophilicity of N-alkoxycarbomyl derivatives of 5-FU, Arch Pharm Chem Sci Ed, 12 (1984) 37.
    • (1984) Arch Pharm Chem Sci Ed , vol.12 , pp. 37
    • Burr, A.1    Bundgaard, H.2
  • 23
    • 0021187201 scopus 로고
    • Prodrugs of 5-FU I: Hydrolysis Kinetics and physiochemical properties of various N-acyl derivatives of 5-FU
    • Burr A & Bundgaard H, Prodrugs of 5-FU I: Hydrolysis Kinetics and physiochemical properties of various N-acyl derivatives of 5-FU, Int J Pharm, 21 (1984) 349.
    • (1984) Int J Pharm , vol.21 , pp. 349
    • Burr, A.1    Bundgaard, H.2
  • 25
    • 0018235648 scopus 로고
    • Antitumor Activity of 1-Hexylcarbamoyl-5-Fluorauracil in a variety Lewis of mouse tumors
    • Iigo M, Hoshi A, Nakamura A & Kuretani K, Antitumor Activity of 1-Hexylcarbamoyl-5-Fluorauracil in a variety Lewis of mouse tumors, Cancer Chemo & Pharma, 1 (1978) 203.
    • (1978) Cancer Chemo & Pharma , vol.1 , pp. 203
    • Iigo, M.1    Hoshi, A.2    Nakamura, A.3    Kuretani, K.4
  • 26
    • 0017104136 scopus 로고
    • Anti-tumor activity of 1-Hexylcarbamoyl-5-Fluorauracil in a variety of experimental tumors
    • Hoshi A, Iigo M, Nakamura A, Yoshida M & Kuretani K, Anti-tumor activity of 1-Hexylcarbamoyl-5-Fluorauracil in a variety of experimental tumors, Gann, 67 (1976) 725.
    • (1976) Gann , vol.67 , pp. 725
    • Hoshi, A.1    Iigo, M.2    Nakamura, A.3    Yoshida, M.4    Kuretani, K.5
  • 27
    • 0026542156 scopus 로고
    • Hydrogels: Swelling, drug loading, and release
    • Kim S W, Bae Y H & Okano T, Hydrogels: swelling, drug loading, and release, Pharm Res, 9 (1992) 283.
    • (1992) Pharm Res , vol.9 , pp. 283
    • Kim, S.W.1    Bae, Y.H.2    Okano, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.