메뉴 건너뛰기




Volumn 6268 LNBI, Issue , 2010, Pages 59-62

An SVM model based on physicochemical properties to predict antimicrobial activity from protein sequences with cysteine knot motifs

Author keywords

Antimicrobial Peptides; Cysteine Knot Motif; Machine Learning; Physicochemical Properties; Support Vector Machine

Indexed keywords

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL FUNCTIONS; ANTIMICROBIAL PEPTIDE; CHARGED RESIDUES; CROSS VALIDATION; CYSTEINE KNOT MOTIF; DATA SETS; MACHINE-LEARNING; NET CHARGES; PHYSICOCHEMICAL PROPERTY; POLYNOMIAL KERNELS; PROTEIN SEQUENCES; PROTEIN STRUCTURES; RANDOM SEQUENCE; SVM MODEL; TRANS-MEMBRANE PROTEINS;

EID: 78049460460     PISSN: 03029743     EISSN: 16113349     Source Type: Book Series    
DOI: 10.1007/978-3-642-15060-9_6     Document Type: Conference Paper
Times cited : (28)

References (12)
  • 1
    • 14544282377 scopus 로고    scopus 로고
    • Antimicrobial Peptides: Pore Formers or Metabolic Inhibitors in Bacteria?
    • Brogden, K.A.: Antimicrobial Peptides: Pore Formers or Metabolic Inhibitors in Bacteria? Nature Microbiology 3, 238-250 (2005)
    • (2005) Nature Microbiology , vol.3 , pp. 238-250
    • Brogden, K.A.1
  • 2
  • 3
    • 0347755460 scopus 로고    scopus 로고
    • APD: The Antimicrobial Peptide Database
    • Wang, Z., Wang, G.: APD: the Antimicrobial Peptide Database. Nucl. Acids Res. 32, D590-D592 (2004)
    • (2004) Nucl. Acids Res. , vol.32
    • Wang, Z.1    Wang, G.2
  • 4
    • 33750304297 scopus 로고    scopus 로고
    • A linguistic model for the rational design of antimicrobial peptides
    • DOI 10.1038/nature05233, PII NATURE05233
    • Loose, C., Jensen, K., Rigoutsos, I., Sphanopoulos, G.: A Linguistic Model for the Rational Design of Antimicrobial Peptides. Nature 443(19), 867-869 (2006) (Pubitemid 44622698)
    • (2006) Nature , vol.443 , Issue.7113 , pp. 867-869
    • Loose, C.1    Jensen, K.2    Rigoutsos, I.3    Stephanopoulos, G.4
  • 5
    • 0031059377 scopus 로고    scopus 로고
    • Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and hemolytic activity of amphipathic helical peptides
    • Dathe, M., Wieprecht, T., Nikolenko, H., Handel, L., Maloy, W.L., MacDonald, D.L., Beyermann, M., Bienert, M.: Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and hemolytic activity of amphipathic helical peptides. FEBS Letters 403, 208-212 (1997)
    • (1997) FEBS Letters , vol.403 , pp. 208-212
    • Dathe, M.1    Wieprecht, T.2    Nikolenko, H.3    Handel, L.4    Maloy, W.L.5    MacDonald, D.L.6    Beyermann, M.7    Bienert, M.8
  • 7
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial Peptides of Innate Immunity
    • Ganz, T.: Defensins: Antimicrobial Peptides of Innate Immunity. Nature Immunology 3, 710-720 (2003)
    • (2003) Nature Immunology , vol.3 , pp. 710-720
    • Ganz, T.1
  • 8
    • 0034793341 scopus 로고    scopus 로고
    • Plant Cyclotides: Circular, Knotted Peptide Toxins
    • Craik, D.J.: Plant Cyclotides: Circular, Knotted Peptide Toxins. Toxicon 39, 1809-1813 (2001)
    • (2001) Toxicon , vol.39 , pp. 1809-1813
    • Craik, D.J.1
  • 9
    • 65449188232 scopus 로고    scopus 로고
    • Jalview Version 2 - A multiple sequence alignment editor and analysis workbench
    • Waterhouse, A.M., Procter, J.B., Martin, D.M.A., Clamp, M., Barton, G.J.: Jalview Version 2 - a multiple sequence alignment editor and analysis workbench. Bioinformatics 25(9), 1189-1191 (2009)
    • (2009) Bioinformatics , vol.25 , Issue.9 , pp. 1189-1191
    • Waterhouse, A.M.1    Procter, J.B.2    Martin, D.M.A.3    Clamp, M.4    Barton, G.J.5
  • 10
    • 34547584314 scopus 로고    scopus 로고
    • Advantages of Combined Transmembrane Topology and Signal Peptide Prediction-the Phobius web server
    • Käll, L., Krogh, A., Sonnhammer, E.L.L.: Advantages of Combined Transmembrane Topology and Signal Peptide Prediction-the Phobius web server. Nucl. Acids Res. 35, W429-W432 (2007)
    • (2007) Nucl. Acids Res. , vol.35
    • Käll, L.1    Krogh, A.2    Sonnhammer, E.L.L.3
  • 11
    • 0000929505 scopus 로고
    • The Hydrophobic Moment Detects Periodicity in Protein Hydrophobicity
    • Eisenberg, D., Weiss, R.M., Terwilliger, T.C.: The Hydrophobic Moment Detects Periodicity in Protein Hydrophobicity. Proc. Natl. Acad. Sci. 81, 140-144 (1984)
    • (1984) Proc. Natl. Acad. Sci. , vol.81 , pp. 140-144
    • Eisenberg, D.1    Weiss, R.M.2    Terwilliger, T.C.3
  • 12
    • 78049464320 scopus 로고    scopus 로고
    • Comprehensive Perl Archive Network, http://search.cpan.org/~lairdm/ Algorithm-SVM-0.11/lib/Algorithm/SVM.pm


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.