Discordance of intraoperative Frozen section analysis with definitive histology of sentinel Lymph nodes in breast cancer surgery: Complementary axillary Lymph node dissection is irrelevant for subsequent systemic therapy

Annals of Surgical Oncology

Volumn 17, Issue 10, 2010, Pages 2690-2695

  Geertsema, D ^a   Gobardhan, P D ^a   Madsen, E V E ^a   Albregts, M ^b   Van Gorp, J ^a   De Hooge, P ^a   Van Dalen, Th ^a  

^a DEPARTMENT OF SURGERY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EOSIN; HEMATOXYLIN;

ADULT; AGED; ARTICLE; AXILLARY LYMPH NODE; AXILLARY LYMPH NODE EXTIRPATION; BREAST CANCER; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; COHORT ANALYSIS; CONSERVATIVE TREATMENT; FROZEN SECTION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; POSTOPERATIVE PERIOD; PROSPECTIVE STUDY; SENTINEL LYMPH NODE; SENTINEL LYMPH NODE BIOPSY; SYSTEMIC THERAPY;

ADULT; AGED; AGED, 80 AND OVER; AXILLA; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; FEMALE; FOLLOW-UP STUDIES; FROZEN SECTIONS; HUMANS; INTRAOPERATIVE PERIOD; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROSPECTIVE STUDIES; SENTINEL LYMPH NODE BIOPSY;

EID: 78049456468     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-010-1052-x     Document Type: Article

References (15)

1. AE Giuliano PS Dale RR Turner DL Morton SW Evans DL Krasne 1995 Improved axillary staging of breast cancer with sentinel lymphadenectomy Ann Surg 3 394 401 10.1097/00000658-199509000-00016
2. DM Miltenburg C Miller TB Karamlou FC Brunicardi 1999 Meta-analysis of sentinel lymph node biopsy in breast cancer J Surg Res 84 138 142 1:STN:280:DyaK1M3ovVWlsw%3D%3D 10.1006/jsre.1999.5629 10357910
3. N Wada S Imoto T Hasebe A Ochiai S Ebihara N Moriyama 2004 Evaluation of intraoperative frozen section diagnosis of sentinel lymph nodes in breast cancer Jpn J Clin Oncol 34 113 117 10.1093/jjco/hyh023 15078905
4. G Cserni D Gregori F Merletti A Sapino MP Mano A Ponti, et al. 2004 Meta-analysis of non-sentinel node metastases associated with micrometastatic sentinel nodes in breast cancer Br J Surg 91 1245 1252 1:STN:280: DC%2BD2cvpsFehtQ%3D%3D 10.1002/bjs.4725 15376203
5. EORTC-AMAROS trial 10981: After mapping of the axilla: radiotherapy or surgery?
6. EVE Madsen PD Gobardhan V Bongers M Albregts J Burgmans P De Hooge, et al. 2007 The impact on post-surgical treatment of sentinel lymph node biopsy of internal mammary lymph nodes in patients with breast cancer Ann Surg Oncol 14 1486 1496 10.1245/s10434-006-9230-6 17253106
7. CW Elston IO Ellis 1991 Pathological prognostic factors in breast cancer. The value of histological grade in breast cancer: experience from a large study with long-term follow-up Histopathology 19 403 410 1:STN:280: DyaK38%2FpvVSltw%3D%3D 10.1111/j.1365-2559.1991.tb00229.x 1757079
8. Sobin ELH, Wittekind Ch. UICC TNM Classification of Malignant Tumours. New York: Wiley-Liss, 2002.
9. Dutch National Guideline Breast Carcinoma, Sep 2008; version 1.1. http://www.oncoline.nl.
10. DA Grabau F Frank E Friis 2005 Intraoperative frozen section examination of axillary sentinel lymph nodes in breast cancer APMIS 113 7 12 1:STN:280:DC%2BD2M%2FkvValuw%3D%3D 10.1111/j.1600-0463.2005.apm1130102.x 15676009
11. C Chao SL Wong D Ackermann Simpson D Simpson MB Carter CM Brown, et al. 2001 Utility of intraoperative frozen section analysis of sentinel lymph nodes in breast cancer Am J Surg 182 609 615 1:STN:280:DC%2BD387gvVWiug%3D%3D 10.1016/S0002-9610(01)00794-2 11839325
12. MR Weiser LL Montgomery B Susnik LK Tan PI Borgen HS Cody 2000 Is routine intraoperative frozen-section examination of sentinel lymph nodes in breast cancer worthwhile? Ann Surg Oncol 7 651 655 1:STN:280:DC%2BD3cvosFGrsw%3D%3D 10.1007/s10434-000-0651-3 11034241
13. P Christiansen E Friis E Balslev D Jensen S Møller 2008 Sentinel node biopsy in breast cancer: Five years experience from Denmark Acta Oncol 47 561 568 10.1080/02841860802023206 18465323
14. M de Boer CH van Deurzen JA van Dijck GF Borm PJ van Diest EM Adang, et al. 2009 Micrometastases or isolated tumor cells and outcome of breast cancer New Engl J Med 361 653 663 10.1056/NEJMoa0904832 19675329
15. GH Lyman AE Giuliano MR Somerfield AB Benson 3rd DC Bodurka HJ Burstein, et al. 2005 American Society of Clinical Oncology Guideline Recommendations for sentinel lymph node biopsy in early-stage breast cancer J Clin Oncol 23 7703 7720 10.1200/JCO.2005.08.001 16157938