Effect of medium composition and light on root and rhinacanthin formation in Rhinacanthus nasutus cultures

Pharmaceutical Biology

Volumn 48, Issue 11, 2010, Pages 1192-1197

  Panichayupakaranant, P ^a   Meerungrueang, W ^a  

^a PRINCE OF SONGKLA UNIVERSITY   (Thailand)

Author keywords

Antifungal; Explants; Medium manipulation; Root culture; Semisolid

Indexed keywords

AGAR; INDOLEBUTYRIC ACID; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; RHINACANTHIN C; RHINACANTHIN D; RHINACANTHIN N; RHINACANTHUS NASUTUS EXTRACT; SUCROSE; UNCLASSIFIED DRUG;

ACANTHACEAE; ARTICLE; CHEMICAL COMPOSITION; CULTURE MEDIUM; CULTURE TECHNIQUE; DRUG DETERMINATION; DRUG ISOLATION; DRY WEIGHT; GAMBORG B5 MEDIUM; LIGHT; LIQUID CULTURE; MURASHIGE AND SKOOG MEDIUM; NONHUMAN; PLANT LEAF; PLANT ROOT; RHINACANTHUS NASUTUS;

ACANTHACEAE; CULTURE MEDIA; CULTURE TECHNIQUES; LIGHT; NAPHTHOQUINONES; PLANT ROOTS;

ACANTHACEAE; RHINACANTHUS NASUTUS;

EID: 78049455549     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903578747     Document Type: Article

References (23)

1. Fuernkranz HA, Nowak CA, Maynard CA (1990): Light effects on in vitro adventitious root formation in axillary shoots of mature Prunus serotina. Physiol Plant 80:337-341.
2. Gangopadhyay M, Sircar D, Mitra A, Bhattacharya S (2008): Hairy root culture of Plumbago indica as a potential source for plumbagin. Biologia Plantarum 52:533-537.
3. Gotoh A, Sakaeda T, Kimura T, Shirakawa T, Wada Y, Wada A, Kimachi T, Takemoto Y, Iida A, Iwakawa S, Hirai M, Tomita H, Okamura N, Nakamura T, Okumura K (2004): Antiproliferative activity of Rhinacanthus nasutus (L.) Kurz extracts and the active moiety, rhinacanthin C. Biol Pharm Bull 27:1070-1074.
4. Johnson M, Vallinayagam S, Manickam VS, Seenp S (2002): Micropropagation of Rhinacanthus nasutus (L.) Kurz.: A medicinally important plant. Phytomorphology 52:331-336.
5. Köhle A, Sommer S, Yazaki K, Ferrer A, Boronat A, Li SM, Heide L (2002): High level expression of chorismate pyruvate-lyase (UbiC) and HMG-CoA reductase in hairy root cultures of Lithospermum erythrorhizon. Plant Cell Physiol 43:894-902.
6. Komaraiah P, Ramakrishna SV, Reddanna P, Kavi Kishor PB (2003): Enhanced production of plumbagin in immobilized cells of Plumbago rosea by elicitation and in situ adsorption. J Biotechnol 101:181-187.
7. Lovell P, Moore K (1969): The effects of light and cotyledon age on growth and root formation in excised cotyledons of Sinapis alba L. Planta 85:351-358.
8. Ogasawara T, Chiba K, Tada M (1993): Production in high-yield of a naphthoquinone by a hairy root culture of Sesamum indicum. Phytochemistry 33:1095-1098.
9. Panichayupakaranant P, Charoonratana T, Sirikatitham A (2009): RP-HPLC analysis of rhinacanthins in Rhinacanthus nasutus: validation and application for the preparation of rhinacanthin high-yielding extract. J Chromatogr Sci 47:705-708.
10. Panichayupakaranant P, Chatkrapunt U, Supavita T (2006): Pharmacognostic and chemical studies on the leaves of Rhinacanthus nasutus. Nigerian J Nat Prod Med 10:1-5.
11. Panichayupakaranant P, De-Eknamkul W (1992): Study on naphthoquinone formation in in vitro cultures of Impatiens balsamina L. Tai J Pharm Sci 16:29-37.
12. Panichayupakaranant P, Tewtrakul S (2002): Plumbagin production by root cultures of Plumbago rosea. Electron J Biotechnol 5:228-232.
13. Pietrosiuk A, Syklowska-Baranek K, Wiedenfeld H, Wolinowska R, Furmanowa M, Jaroszyk E (2006): The shikonin derivatives and pyrrolizidine alkaloids in hairy root cultures of Lithospermum canescens (Michx.) Lehm. Plant Cell Rep 25:1052-1058.
14. Rates SMK (2001): Plants as sources of drugs. Toxicon 39:603-613.
15. Sendl A, Chen JL, Jolad SD, Stoddart C, Rozhon E, Kernan M (1996): Two new naphthoquinones with antiviral activity from Rhinacanthus nasutus. J Nat Prod 59:808-811.
16. Tewtrakul S, Tansakul P, Panichayupakaranant P (2009a): Effects of rhinacanthins from Rhinacanthus nasutus on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha releases using RAW264.7 macrophage cells. Phytomedicine 16:581-585.
17. Tewtrakul S, Tansakul P, Panichayupakaranant P (2009b): Anti-allergic principles of Rhinacanthus nasutus leaves. Phytomedicine 16:929-934.
18. Van der Krieken WM, Breteler H, Visser MHM, Jordi W (1992): Effect of light and ribofavin on indolebutyric acid-induced root formation on apple in vitro. Physiol Plant 85:589-594.
19. Wink M (2003): Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective. Phytochemistry 64:3-19.
20. Wu TS, Hsu HC, Wu PL, Teng CM, Wu CY (1998): Rhinacanthin Q, A naphthoquinone from Rhinacanthus nasutus and its biological activity. Phytochemistry 40:2001-2003.
21. Yazaki K, Matsuoka H, Shimomura K, Bechthold A, Sato F (2001): A novel dark-inducible protein, LeDI-2, and its involvement in rootspecific secondary metabolism in Lithospermum erythrorhizon. Plant Physiol 125:1831-1841.
22. Yazaki K, Matsuoka H, Ujihara T, Sato F (1999): Shikonin biosynthesis in Lithospermum erythrorhizon: Light-induced negative regulation of secondary metabolism. Plant Biotechnol 16:335-342.
23. Yazaki K (2001): Root-specific production of secondary metabolites: Regulation of shikonin biosynthesis by light in Lithospermum erythrorhizon. Nat Med 55:49-54.