Linking changes in epithelial morphogenesis to cancer mutations using computational modeling

PLoS Computational Biology

Volumn 6, Issue 8, 2010, Pages

  Rejniak, Katarzyna A ^a,b   Wang, Shizhen E ^c   Bryce, Nicole S ^d,f   Chang, Hang ^e   Parvin, Bahram ^e   Jourquin, Jerome ^d   Estrada, Lourdes ^d   Gray, Joe W ^e   Arteaga, Carlos L ^d   Weaver, Alissa M ^d   Quaranta, Vito ^d   Anderson, Alexander R A ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^f UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; COMPUTATION THEORY; MAPPING; TUMORS;

APOPTOTIC; CELL LINES; CELL SENSITIVITY; COMPUTATIONAL MODELLING; EPITHELIAL ARCHITECTURE; EPITHELIAL MORPHOGENESIS; EPITHELIAL TISSUE; INVASIVE TUMORS; MAMMARY GLAND; MODELING PARAMETERS;

MORPHOLOGY;

APOPTOSIS; ARTICLE; BREAST CELL; CANCER GENETICS; CELL AGGREGATION; CELL KINETICS; CELL MUTANT; COMPUTER MODEL; CONTROLLED STUDY; CROSS LINKING; EPITHELIUM CELL; EXTRACELLULAR MATRIX; GENE MAPPING; GENE MUTATION; HIGH THROUGHPUT SCREENING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; MATHEMATICAL COMPUTING; MORPHOGENESIS; ONCOGENE NEU; PHENOTYPIC VARIATION; THREE DIMENSIONAL IMAGING;

EID: 78049426469     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000900     Document Type: Article

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