Hepatoma-derived growth factor-related protein-3: A new neurotrophic and neurite outgrowth-promoting factor for cortical neurons

Journal of Neuroscience Research

Volumn 88, Issue 16, 2010, Pages 3610-3620

  Abouzied, Mekky M ^a   El Tahir, Heba M ^a   Gieselmann, Volkmar ^a   Franken, Sebastian ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

HDGF; Neuronal cell culture; Neuronal survival

Indexed keywords

HEPATOMA DERIVED GROWTH FACTOR; HEPATOMA DERIVED GROWTH FACTOR RELATED PROTEIN 3; NEURITE PROMOTING FACTOR; NEUROTROPHIC FACTOR; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL SURVIVAL; CONTROLLED STUDY; EXTRACELLULAR MATRIX; NERVE CELL; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NERVE FIBER GROWTH; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANIMALS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CEREBRAL CORTEX; MICE; NEURITES; NEURONS; NUCLEAR PROTEINS;

EID: 78049426460     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22507     Document Type: Article

References (32)

1. Abouzied MM, Baader SL, Dietz F, Kappler J, Gieselmann V, Franken S. 2004. Expression patterns and different subcellular localization of the growth factors HDGF (hepatoma-derived growth factor) and HRP-3 (HDGF-related protein-3) suggest functions in addition to their mitogenic activity. Biochem J 378: 169-176.
2. Abouzied MM, El-Tahir HM, Prenner L, Haberlein H, Gieselmann V, Franken S. 2005. Hepatoma-derived growth factor. Significance of amino acid residues 81-100 in cell surface interaction and proliferative activity. J Biol Chem 280: 10945-10954.
3. Ayaki M, Sueno T, Singh DP, Chylack LTJr, Shinohara T. 1999. Antibodies to lens epithelium-derived growth factor (LEDGF) kill epithelial cells of whole lenses in organ culture. Exp Eye Res 69: 139-142.
4. Bianchi ME. 2007. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81: 1-5.
5. Burgess WH, Maciag T. 1989. The heparin-binding (fibroblast) growth factor family of proteins. Annu Rev Biochem 58: 575-606.
6. Dietz F, Franken S, Yoshida K, Nakamura H, Kappler J, Gieselmann V. 2002. The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies. Biochem J 366: 491-500.
7. El-Tahir HM, Dietz F, Dringen R, Schwabe K, Strenge K, Kelm S, Abouzied MM, Gieselmann V, Franken S. 2006. Expression of hepatoma-derived growth factor family members in the adult central nervous system. BMC Neurosci 7: 6.
8. El-Tahir HM, Abouzied MM, Gallitzendoerfer R, Gieselmann V, Franken S. 2009. Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons. J Biol Chem 284: 11637-11651.
9. +-ATPase. J Biol Chem 273: 544-551.
10. Harris HE, Raucci A. 2006. Alarmin(g) news about danger: workshop on innate danger signals and HMGB1. EMBO Rep 7: 774-778.
11. Hori O, Brett J, Slattery T, Cao R, Zhang J, Chen JX, Nagashima M, Lundh ER, Vijay S, Nitecki D, et al. 1995. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 270: 25752-25761.
12. Ikegame K, Yamamoto M, Kishima Y, Enomoto H, Yoshida K, Suemura M, Kishimoto T, Nakamura H. 1999. A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus. Biochem Biophys Res Commun 266: 81-87.
13. Inomata Y, Hirata A, Koga T, Kimura A, Singh DP, Shinohara T, Tanihara H. 2003. Lens epithelium-derived growth factor: neuroprotection on rat retinal damage induced by N-methyl-D-aspartate. Brain Res 991: 163-170.
14. Izumoto Y, Kuroda T, Harada H, Kishimoto T, Nakamura H. 1997. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem Biophys Res Commun 238: 26-32.
15. Kinnunen T, Raulo E, Nolo R, Maccarana M, Lindahl U, Rauvala H. 1996. Neurite outgrowth in brain neurons induced by heparin-binding growth-associated molecule (HB-GAM) depends on the specific interaction of HB-GAM with heparan sulfate at the cell surface. J Biol Chem 271: 2243-2248.
16. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
17. Li F, Shetty AK, Sugahara K. 2007. Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways. J Biol Chem 282: 2956-2966.
18. Marubuchi S, Okuda T, Tagawa K, Enokido Y, Horiuchi D, Shimokawa R, Tamura T, Qi ML, Eishi Y, Watabe K, Shibata M, Nakagawa M, Okazawa H. 2006. Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration. J Neurochem 99: 70-83.
19. Matsui H, Lin LR, Singh DP, Shinohara T, Reddy VN. 2001. Lens epithelium-derived growth factor: increased survival and decreased DNA breakage of human RPE cells induced by oxidative stress. Invest Ophthalmol Vis Sci 42: 2935-2941.
20. Nakamura M, Singh DP, Kubo E, Chylack LTJr, Shinohara T. 2000. LEDGF: survival of embryonic chick retinal photoreceptor cells. Invest Ophthalmol Vis Sci 41: 1168-1175.
21. Oppenheim RW. 1996. Neurotrophic survival molecules for motoneurons: an embarrassment of riches. Neuron 17: 195-197.
22. Ortega-Paino E, Fransson J, Ek S, Borrebaeck CAK. 2008. Functionally associated targets in mantle cell lymphoma as defined by DNA microarrays and RNA interference. Blood 111: 1617-1624.
23. Raulo E, Julkunen I, Merenmies J, Pihlaskari R, Rauvala H. 1992. Secretion and biological activities of heparin-binding growth-associated molecule. Neurite outgrowth-promoting and mitogenic actions of the recombinant and tissue-derived protein. J Biol Chem 267: 11408-11416.
24. Raulo E, Tumova S, Pavlov I, Pekkanen M, Hienola A, Klankki E, Kalkkinen N, Taira T, Kilpelainen I, Rauvala H. 2005. The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons. J Biol Chem 280: 41576-41583.
25. Rauvala H. 1984. Neurite outgrowth of neuroblastoma cells: dependence on adhesion surface-cell surface interactions. J Cell Biol 98: 1010-1016.
26. Revest JM, DeMoerlooze L, Dickson C. 2000. Fibroblast growth factor 9 secretion is mediated by a non-cleaved amino-terminal signal sequence. J Biol Chem 275: 8083-8090.
27. Sue SC, Chen JY, Lee SC, Wu WG, Huang TH. 2004. Solution structure and heparin interaction of human hepatoma-derived growth factor. J Mol Biol 343: 1365-1377.
28. Sue S-C, Lee W-T, Tien S-C, Lee S-C, Yu J-G, Wu W-J, Wu W-G, Huang T-H. 2007. PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin. J Mol Biol 367: 456.
29. Yuen EC, Mobley WC. 1995. Therapeutic applications of neurotrophic factors in disorders of motor neurons and peripheral nerves. Mol Med Today 1: 278-286.
30. Zhao H, Wang Y, Yin ZQ. 2008a. A comparison of LEDGFp52 and CNTF on the in vitro growth of rat retinal ganglion cell neurites. Neurosci Lett 440: 9-13.
31. Zhao HS, Chen SJ, Wu N, Wang XQ, Yin ZQ, Wang Y. 2008b. LEDGFp52 controls rat retinal ganglion cell neurite growth in culture and regulates specific neuronal growth-associated genes and protein production. J Int Med Res 36: 815-829.
32. Zhou Z, Yamamoto Y, Sugai F, Yoshida K, Kishima Y, Sumi H, Nakamura H, Sakoda S. 2004. Hepatoma-derived growth factor is a neurotrophic factor harbored in the nucleus. J Biol Chem 279: 27320-27326.