Characterization and online detection of surfactin isomers based on HPLC-MSn analyses and their inhibitory effects on the overproduction of nitric oxide and the release of TNF-α and IL-6 in LPS-induced macrophages

Marine Drugs

Volumn 8, Issue 10, 2010, Pages 2605-2618

  Tang, Jin Shan ^a   Zhao, Feng ^b   Gao, Hao ^a,c   Dai, Yi ^a   Yao, Zhi Hong ^a   Hong, Kui ^d   Li, Jia ^c   Ye, Wen Cai ^a   Yao, Xin Sheng ^a  

^a JINAN UNIVERSITY   (China)

^b YANTAI UNIVERSITY   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^d INSTITUTE OF TROPICAL BIOSCIENCE AND BIOTECHNOLOGY   (China)

Author keywords

Anti inflammatory activity; Bacillus sp.; LC MS; Surfactin isomer

Indexed keywords

HYDROCORTISONE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; SURFACTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DRUG DETERMINATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; ISOMERISM; MACROPHAGE ACTIVATION; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; STRUCTURE ACTIVITY RELATION;

BACILLUS SP.; BACTERIA (MICROORGANISMS); MURINAE;

EID: 78049423560     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md8102605     Document Type: Article

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