Good clinical response to gefitinib in a non-small cell lung cancer patient harboring a rare somatic epidermal growth factor gene point mutation; codon 768 AGC > ATC in exon 20 (S768I)

Japanese Journal of Clinical Oncology

Volumn 40, Issue 11, 2010, Pages 1105-1109

  Masago, Katsuhiro ^a   Fujita, Shiro ^b   Irisa, Kaoru ^a   Kim, Yung Hak ^a   Ichikawa, Masataka ^a   Mio, Tadashi ^a   Mishima, Michiaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b INSTITUTE OF BIOMEDICAL RESEARCH AND INNOVATION   (Japan)

Author keywords

Epidermal growth factor receptor; Non small cell lung cancer; Tyrosine kinase inhibitor

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; PROTEIN TYROSINE KINASE;

AGED; ARTICLE; CASE REPORT; CODON; DRUG EFFICACY; EXON; GENE DELETION; HUMAN; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; MALE; POINT MUTATION; PROTEIN DOMAIN; SOMATIC MUTATION; TREATMENT RESPONSE;

AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; EXONS; HUMANS; LUNG NEOPLASMS; MALE; POINT MUTATION; PROGNOSIS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 78049415502     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hyq087     Document Type: Article

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