Multiple roles of CD4 and CD8 in T cell activation

Journal of Immunology

Volumn 185, Issue 5, 2010, Pages 2643-2644

  Koretzky, Gary A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADAPTIVE IMMUNITY; ANTIGEN BINDING; ANTIGEN FUNCTION; ANTIGEN PRESENTATION; CELLULAR IMMUNITY; NOTE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMUS; ANIMAL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COMPARATIVE STUDY; HISTORY; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM;

ALLERGY AND IMMUNOLOGY; ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HISTORY, 20TH CENTURY; HUMANS; LYMPHOCYTE ACTIVATION;

EID: 78049414117     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1090076     Document Type: Note

References (23)

1. Miller, J. F. 1961. Immunological function of the thymus. Lancet 2: 748-749.
2. Cooper, M. D., R. D. Peterson, and R. A. Good. 1965. Delineation of the Thymic and Bursal Lymphoid Systems in the Chicken. Nature 205: 143-146.
3. Bach, F. H., M. L. Bach, and P. M. Sondel. 1976. Differential function of major histocompatibility complex antigens in T-lymphocyte activation. Nature 259: 273-281.
4. Cantor, H., and E. A. Boyse. 1977. Regulation of cellular and humoral immune responses by T-cell subclasses. Cold Spring Harb. Symp. Quant. Biol. 41: 23-32.
5. Cantor, H., and E. A. Boyse. 1975. Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen. J. Exp. Med. 141: 1376-1389.
6. Shiku, H., P. Kisielow, M. A. Bean, T. Takahashi, E. A. Boyse, H. F. Oettgen, and L. J. Old. 1975. Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells. J. Exp. Med. 141: 227-241.
7. Swain, S. L. 1983. T cell subsets and the recognition of MHC class. Immunol. Rev. 74: 129-142.
8. Doyle, C., and J. L. Strominger. 1987. Interaction between CD4 and class II MHC molecules mediates cell adhesion. Nature 330: 256-259.
9. Norment, A. M., R. D. Salter, P. Parham, V. H. Engelhard, and D. R. Littman. 1988. Cell-cell adhesion mediated by CD8 and MHC class I molecules. Nature 336: 79-81.
10. Sarmiento, M., A. L. Glasebrook, and F. W. Fitch. 1980. IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. J. Immunol. 125: 2665-2672.
11. Marrack, P., R. Endres, R. Shimonkevitz, A. Zlotnik, D. Dialynas, F. Fitch, and J. Kappler. 1983. The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J. Exp. Med. 158: 1077-1091.
12. Gay, D., P. Maddon, R. Sekaly, M. A. Talle, M. Godfrey, E. Long, G. Goldstein, L. Chess, R. Axel, J. Kappler, et al. 1987. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature 328: 626-629.
13. Bank, I., and L. Chess. 1985. Perturbation of the T4 molecule transmits a negative signal to T cells. J. Exp. Med. 162: 1294-1303.
14. Rosoff, P. M., S. J. Burakoff, and J. L. Greenstein. 1987. The role of the L3T4 molecule in mitogen and antigen-activated signal transduction. Cell 49: 845-853.
15. Ledbetter, J. A., C. H. June, P. S. Rabinovitch, A. Grossmann, T. T. Tsu, and J. B. Imboden. 1988. Signal transduction through CD4 receptors: stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD3/T cell receptor. Eur. J. Immunol. 18: 525-532.
16. Rudd, C. E., J. M. Trevillyan, J. D. Dasgupta, L. L. Wong, and S. F. Schlossman. 1988. The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. Proc. Natl. Acad. Sci. USA 85: 5190-5194.
17. lck. Cell 55: 301-308.
18. Samelson, L. E., J. Harford, R. H. Schwartz, and R. D. Klausner. 1985. A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A. Proc. Natl. Acad. Sci. USA 82: 1969-1973.
19. Samelson, L. E., M. D. Patel, A. M. Weissman, J. B. Harford, and R. D. Klausner. 1986. Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor. Cell 46: 1083-1090.
20. Voronova, A. F., J. E. Buss, T. Patschinsky, T. Hunter, and B. M. Sefton. 1984. Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells. Mol. Cell. Biol. 4: 2705-2713.
21. Marth, J. D., R. Peet, E. G. Krebs, and R.M. Perlmutter. 1985. A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA. Cell 43: 393-404.
22. Voronova, A. F., and B. M. Sefton. 1986. Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion. Nature 319: 682-685.
23. Marth, J. D., D. B. Lewis, C. B. Wilson, M. E. Gearn, E. G. Krebs, and R. M. Perlmutter. 1987. Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinases. EMBO J. 6: 2727-2734.