Visualizing ribosome biogenesis: Parallel assembly pathways for the 30S subunit

Science

Volumn 330, Issue 6004, 2010, Pages 673-677

  Mulder, Anke M ^a   Yoshioka, Craig ^a   Beck, Andrea H ^a   Bunner, Anne E ^a   Milligan, Ronald A ^a   Potter, Clinton S ^a   Carragher, Bridget ^a   Williamson, James R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMONITORING; CELL ORGANELLE; COLIFORM BACTERIUM; DATA SET; DEVELOPMENTAL BIOLOGY; ELECTRON MICROSCOPY; MOLECULAR ANALYSIS; POPULATION STRUCTURE; PROTEIN; SPECTROMETRY; VISUAL ANALYSIS;

ARTICLE; BIOGENESIS; ELECTRON MICROSCOPY; MASS SPECTROMETRY; PRIORITY JOURNAL; RIBOSOME; STRUCTURE ANALYSIS;

BACTERIAL PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETICS; MASS SPECTROMETRY; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; RIBOSOMAL PROTEINS; RIBOSOME SUBUNITS, SMALL, BACTERIAL; RNA, BACTERIAL; RNA, RIBOSOMAL;

ESCHERICHIA COLI;

EID: 78049406997     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1193220     Document Type: Article

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21. This work was supported by the NIH (grants RR175173, R37-GM-53757, and GM-52468) and the NSF (graduate research fellowship to A.M.M.). The EM data collection and analysis were conducted at the National Resource for Automated Molecular Microscopy, which is supported by the NIH through the National Center for Research Resources P41 program (grants RR175173 and RR023093). We thank N. R. Voss and members of the Automated Molecular Imaging and Williamson laboratories for critical discussion of experiments. MAP, structure factors, and layer-line data have been deposited at EMDB with accession code EMD-1783.