Retinoid supplementation of differentiating human neural progenitors and embryonic stem cells leads to enhanced neurogenesis in vitro

Journal of Neuroscience Methods

Volumn 193, Issue 2, 2010, Pages 239-245

  Christie, Victoria B ^a,b   Maltman, Daniel J ^a,b   Henderson, Andrew P ^a,b   Whiting, Andrew ^a   Marder, Todd B ^a   Lako, Majlinda ^c   Przyborski, Stefan A ^a,b  

^a DURHAM UNIVERSITY   (United Kingdom)

^b ReproCELL Inc   (Japan)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cell culture; EC23; Media supplement; Neural differentiation; Neuron; Retinoic acid; Synthetic retinoid

Indexed keywords

EC 23; RETINOIC ACID; RETINOID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DIET SUPPLEMENTATION; DRUG MECHANISM; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOMERIZATION; MOTONEURON; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PRIORITY JOURNAL;

BENZOIC ACIDS; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; EMBRYONIC STEM CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR NEURONS; NEUROGENESIS; RETINOIDS; TETRAHYDRONAPHTHALENES; TRETINOIN; TUBULIN;

EID: 78049406305     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2010.08.022     Document Type: Article

References (19)

1. Brewer G.J., Torricelli J.R., Evege E.K., Price P.J. Optimized survival of hippocampal neurons in B27-supplemented neurobasal, a new serum-free medium combination. J Neurosci Res 1993, 35:567-576.
2. Cai C., Grabel L. Directing the differentiation of embryonic stem cells to neural stem cells. Dev Dyn 2007, 236:3255-3266.
3. Carlotti M.E., Rossatto V., Gallarate M. Vitamin A and vitamin A palmitate stability over time and under UVA and UVB radiation. Int J Pharm 2002, 240:85-94.
4. Chen Y., Stevens B., Chang J., Milbrandt J., Barres B.A., Hell J.W. NS21: re-defined and modified supplement B27 for neuronal cultures. J Neurosci Methods 2008, 171:239-247.
5. Christie V.B., Marder T.B., Whiting A., Przyborski S.A. The role of retinoids in the adult nervous system and their therapeutic potential. Mini Rev Med Chem 2008, 8:601-608.
6. Christie V.B., Barnard J.H., Batsanov A.S., Bridgens C.E., Cartmell E.B., Collings J.C., et al. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org Biomol Chem 2008, 6:3497-3507.
7. Donato R., Miljan E.A., Hines S.J., Aouabdi S., Pollock K., Patel S., et al. Differential development of neuronal physiological responsiveness in two human neural stem cell lines. BMC Neurosci 2007, 8:36.
8. Erceg S., Lainez S., Ronaghi M., Stojkovic P., Perez-Arago M.A., Moreno-Manzano V., et al. Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions. PLoS ONE 2008, 3:e2122.
9. Hu B.Y., Zhang S.C. Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs. Methods Mol Biol 2010, 636:123-137.
10. Maden M. Retinoic acid in the development, regeneration and maintenance of the nervous system. Nat Rev Neurosci 2007, 8:755-765.
11. Maltman D.J., Christie V.B., Collings J.C., Barnard J.H., Fenyk S., Marder T.B., et al. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol Biosyst 2009, 5:458-471.
12. Mena M.A., Casarejos M.J., Estrada C., de Yebenes J.G. Effects of retinoic acid on NB 69 human neuroblastoma cells and fetal rat mid brain neurons. J Neural Transm Park Dis Dement Sect 1994, 8:85-97.
13. Murayama A., Suzuki T., Matsui M. Photoisomerization of retinoic acids in ethanol under room light: a warning for cell biological study of geometrical isomers of retinoids. J Nutr Sci Vitaminol (Tokyo) 1997, 43:167-176.
14. Przyborski S.A., Cambray-Deakin M.A. Developmental regulation of MAP2 variants during neuronal differentiation in vitro. Brain Res Dev Brain Res 1995, 89:187-201.
15. Simeone A., Acampora D., Arcioni L., Andrews P.W., Boncinelli E., Mavilio F. Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells. Nature 1990, 346:763-766.
16. Suzuki T., Kunchala S.R., Matsui M., Murayama A. Molecular flexibility of retinoic acid under white fluorescent light. J Nutr Sci Vitaminol (Tokyo) 1998, 44:729-736.
17. Takahashi J., Palmer T.D., Gage F.H. Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol 1999, 38:65-81.
18. Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., Swiergiel J.J., Marshall V.S., et al. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282(5391):1145-1147.
19. Yabe J.T., Wang F.S., Chylinski T., Katchmar T., Shea T.B. Selective accumulation of the high molecular weight neurofilament subunit within the distal region of growing axonal neurites. Cell Motil Cytoskeleton 2001, 50:1-12.