Montelukast in the treatment of bronchiolitis, a multi-center, randomized, three-blind, placebo-controlled trial

Chinese Journal of Evidence-Based Medicine

Volumn 10, Issue 9, 2010, Pages 1011-1015

  Bai, Jun ^a   Xu, Pei Ru ^b  

^a Department of Pediatrics   (China)

^b XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Asthma; Bronchial hyperresponsiveness; Bronchiolitis; Infant; Montelukast

Indexed keywords

BUDESONIDE; EOSINOPHIL CATIONIC PROTEIN; IMMUNOGLOBULIN E; MONTELUKAST; PLACEBO;

ARTICLE; ASTHMA; BRONCHIOLITIS; BRONCHUS HYPERREACTIVITY; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; HUMAN; INCIDENCE; INFANT; MULTICENTER STUDY; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SHORT COURSE THERAPY; TREATMENT OUTCOME; WHEEZING;

EID: 78049398479     PISSN: 16722531     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Pediatrics, 2006, 118(4): 1774.
2. Wang SZ, Bao YZ, Rosenberger CL. IL-12 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection. Immunol, 2004, 173 (6): 4040-4049.
3. Sigurs N, Bjamason R, Sigurbergason F, et al. Respiratory syucytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med, 2000, 161: 1501-1507.
4. Abul-Ainine A, Luyt D. Short term effects of adrenaline in bronchiolitis: a randomized controlled trial. Arch Dis Child, 2008, 86(4): 276-279.
5. Van Woensel JB, Van Aalderen WM. Treatment for bronchiolitis: the story continues. Lancet, 2002, 360(9327): 101-102.
6. Hendeison WR, Tang Lo, Chu ST, et al. A role for cystinyl leukotrienes in airway remodeling in a mouse asthma mode. Am J Respir Crit Care Med, 2002, 165: 108-116.
7. Law BJ, Carbonell-Estrany X, Simors EA. An update on respiratory Syncytial Virus epidemiology: a developed country perspective. Respir Med, 2002, 96(Suppl B): S1-7.
8. Collins PL, MeIntosh K, Chnaoek RM. Respiratory Syncytial Viurs in Virology 3rd ed New York. Lippincott-Raven Publisher, 1996, 1313.
9. Who ME, Majzoub JA. Asthma, steroids and growth. Eng J Med, 2000, 343(15): 1113-1114.
10. Cade A, Brownlee KG, Corrway SP, et al. Randomised placebo ontrolled trial of nebulised corticostrolitis in acute resoiratory syncytial viral bronchiolitis. Arch Dis Child, 2000, 82: 126-130.
11. Hans Bisgaard for the Study Group on Montelukast and Respiratory Syncytial Virus. A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis. Respir Crit Care Med, 2003, 167(3): 379-383.
12. Knorr B. Pharmacokinetics and safety of montelukast in children aged 3 to 6 months. Clin Pharmacol, 2006, 46(6): 620.
13. Knorr B, Franchi LM, Bisgaard H, et al. Montolukast,a leukoyriene receotor antagonist, for the treatment of persistant asthma in children aged 2 to 5 years. Pediatrics, 2001, 108: E48.