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Volumn 27, Issue 7, 2010, Pages 215-231

Nanoparticulate drug delivery systems for cancer chemotherapy

Author keywords

brain targeting; cytotoxicity; intracellular trafficking; opsonization; Polymeric lipid nanoparticles

Indexed keywords

ASPARAGINASE MACROGOL; CYCLOSPORIN A; DAUNORUBICIN; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; IMATINIB; INDOMETACIN; LEUCINE ENKEPHALIN[2 DEXTRO ALANINE 6 ARGININE]; LIPOSOME; LOPERAMIDE; MACROGOL; NANOCAPSULE; NANOPARTICLE; NANOSPHERE; PACLITAXEL; POLY(ETHYL 2 CYANOACRYLATE); POLYGLACTIN; POLYSORBATE 20; POLYSORBATE 40; POLYSORBATE 60; POLYSORBATE 80; SOLID LIPID NANOPARTICLE; TENIPOSIDE; TUBOCURARINE CHLORIDE; VINBLASTINE; VINCRISTINE;

EID: 78049336287     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.3109/09687688.2010.510804     Document Type: Review
Times cited : (137)

References (88)
  • 1
    • 0027133051 scopus 로고
    • In vitro extended-release properties of drug-loaded poly (DL-lactic acid) NPs produced by a salting-out procedure
    • Allenmann E, Leroux JC, Gurny R, Doelker E. 1993. In vitro extended-release properties of drug-loaded poly (DL-lactic acid) NPs produced by a salting-out procedure. Pharm Res 10:1732-1737.
    • (1993) Pharm Res , vol.10 , pp. 1732-1737
    • Allenmann, E.1    Leroux, J.C.2    Gurny, R.3    Doelker, E.4
  • 2
    • 33344467489 scopus 로고    scopus 로고
    • Preparation and characterization of protein-loaded N-trimethyl Chitosan nanoparticles as nasal delivery system
    • Amidi M, Romeijn SG, Borchard G, Junginger HE, Hennink WE, Jiskoot W. 2006. Preparation and characterization of protein-loaded N-trimethyl Chitosan nanoparticles as nasal delivery system. J Control Rel 111:107-116.
    • (2006) J Control Rel , vol.111 , pp. 107-116
    • Amidi, M.1    Romeijn, S.G.2    Borchard, G.3    Junginger, H.E.4    Hennink, W.E.5    Jiskoot, W.6
  • 4
    • 33645512835 scopus 로고    scopus 로고
    • Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues
    • Bilati U, Allemann E, Doelker E. 2005. Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues. AAPS PharmSciTech 6:E594-604.
    • (2005) AAPS PharmSciTech , vol.6
    • Bilati, U.1    Allemann, E.2    Doelker, E.3
  • 5
    • 28244474457 scopus 로고    scopus 로고
    • Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy
    • Borgia SL, Regehly M, Sivaramakrishnan R, Mehnert W, Korting HC, Danker K, Röder B, Kramer KD, Korting MS. 2005. Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. J Control Rel 110:151-163.
    • (2005) J Control Rel , vol.110 , pp. 151-163
    • Borgia, S.L.1    Regehly, M.2    Sivaramakrishnan, R.3    Mehnert, W.4    Korting, H.C.5    Danker, K.6    Röder, B.7    Kramer, K.D.8    Korting, M.S.9
  • 6
    • 36549034234 scopus 로고    scopus 로고
    • Polymer and nanopar-ticles: Intelligent tools for intracellular targeting?
    • Breunig M, Bauer S, Goepferich A. 2008. Polymer and nanopar-ticles: Intelligent tools for intracellular targeting? Eur J. Pharm Biopharm 68:112-128.
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 112-128
    • Breunig, M.1    Bauer, S.2    Goepferich, A.3
  • 7
  • 8
    • 34547178393 scopus 로고    scopus 로고
    • Particle shape: A new design parameter for micro and nanoscale drug delivery carriers
    • Champion JA, Katare YK, Mitragotri S. 2007. Particle shape: A new design parameter for micro and nanoscale drug delivery carriers. J Control Rel 121:3-9.
    • (2007) J Control Rel , vol.121 , pp. 3-9
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 9
    • 0018387102 scopus 로고
    • Polycyanoacrylate nanocapsules as potential lysosomatropic carriers: Preparation, morphological and sorp-tive properties
    • Couvreur P, Kante B, Roland M, Guiot P, Bauduin P. Speiser P. 1979. Polycyanoacrylate nanocapsules as potential lysosomatropic carriers: Preparation, morphological and sorp-tive properties. J Pharm Pharmacol 31:331-332.
    • (1979) J Pharm Pharmacol , vol.31 , pp. 331-332
    • Couvreur, P.1    Kante, B.2    Roland, M.3    Guiot, P.4    Bauduin, P.5    Speiser, P.6
  • 10
    • 33745605771 scopus 로고    scopus 로고
    • Nanotechnology: Intelligent design to treat complex disease
    • Couvreur P, Vauthier C. 2006. Nanotechnology: Intelligent design to treat complex disease. Pharm Res 23:1417-1450.
    • (2006) Pharm Res , vol.23 , pp. 1417-1450
    • Couvreur, P.1    Vauthier, C.2
  • 11
    • 0028255997 scopus 로고
    • Encapsulation of mitomycin C in albumin microspheres markedly alters pharmacokinetics, drug quinine reduction in tumor tissue and antitumor activity
    • Cummings J, Allan L, Smyth J. 1994. Encapsulation of mitomycin C in albumin microspheres markedly alters pharmacokinetics, drug quinine reduction in tumor tissue and antitumor activity. Biochem Pharmacol 47:1345-1356.
    • (1994) Biochem Pharmacol , vol.47 , pp. 1345-1356
    • Cummings, J.1    Allan, L.2    Smyth, J.3
  • 12
    • 0029041515 scopus 로고
    • Liposomal doxorubicin-induced toxicity: Depletion and impairment of phagocytic activity of liver macro-phages
    • Daemen T, Hofstede G, Kate MTT, Woudenberg IAJMB, Scherphof G. 1995. Liposomal doxorubicin-induced toxicity: Depletion and impairment of phagocytic activity of liver macro-phages. Int J Cancer 61:716-721.
    • (1995) Int J Cancer , vol.61 , pp. 716-721
    • Daemen, T.1    Hofstede, G.2    Kate, M.T.T.3    Woudenberg, I.A.J.M.B.4    Scherphof, G.5
  • 13
    • 0037043080 scopus 로고    scopus 로고
    • Biochemical and biophysical characteristics of lipoplexes pertinent to solid tumor gene therapy
    • Dass CR. 2002. Biochemical and biophysical characteristics of lipoplexes pertinent to solid tumor gene therapy. Int J Pharm 241:1-25.
    • (2002) Int J Pharm , vol.241 , pp. 1-25
    • Dass, C.R.1
  • 14
    • 0035859983 scopus 로고    scopus 로고
    • Chitosan nano-particles: A new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporine A
    • De Campos AM, Sanchez A, Alonso MJ. 2001. Chitosan nano-particles: A new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporine A. Int J Pharm 224:159-168.
    • (2001) Int J Pharm , vol.224 , pp. 159-168
    • De Campos, A.M.1    Sanchez, A.2    Alonso, M.J.3
  • 15
    • 33947099909 scopus 로고    scopus 로고
    • Encapsulation of 9-nitrocamptothecin, a novel anticancer drug, in biodegradable nanoparticles: Factorial design, characterization and release kinetics
    • Derakhshandeh K, Erfan M, Dadashzadeh S. 2007. Encapsulation of 9-nitrocamptothecin, a novel anticancer drug, in biodegradable nanoparticles: Factorial design, characterization and release kinetics. Eur J Pharm Biopharm 66:34-41.
    • (2007) Eur J Pharm Biopharm , vol.66 , pp. 34-41
    • Derakhshandeh, K.1    Erfan, M.2    Dadashzadeh, S.3
  • 17
    • 33646536352 scopus 로고    scopus 로고
    • Evaluation of ciprofloxacin-loaded Eudragit RS 100 or Rl 100/PLGA nanoparticles
    • Dillen K, Vandervoort J, Mooter GV, Ludwig A. 2006. Evaluation of ciprofloxacin-loaded Eudragit RS 100 or Rl 100/PLGA nanoparticles. Int J Pharm 314:72-82.
    • (2006) Int J Pharm , vol.314 , pp. 72-82
    • Dillen, K.1    Vandervoort, J.2    Mooter, G.V.3    Ludwig, A.4
  • 18
    • 0037047627 scopus 로고    scopus 로고
    • Material science: Soft surface: Polymer vesicles
    • Discher DE, Eisenberg A. 2002. Material science: soft surface: polymer vesicles. Science 297:967-973.
    • (2002) Science , vol.297 , pp. 967-973
    • Discher, D.E.1    Eisenberg, A.2
  • 19
    • 33747840618 scopus 로고    scopus 로고
    • Polymer conjugates as anticancer nanomedicines
    • Duncan R. 2006. Polymer conjugates as anticancer nanomedicines. Nat Rev Cancer 6:688-701.
    • (2006) Nat Rev Cancer , vol.6 , pp. 688-701
    • Duncan, R.1
  • 20
    • 34250685362 scopus 로고    scopus 로고
    • Nanosystems for simultaneous imaging and drug delivery to T cells
    • Fahmy TM, Fong PM, Park J, Constable T, Saltzman WM. 2007. Nanosystems for simultaneous imaging and drug delivery to T cells. AAPS J 9(2):E171-180.
    • (2007) AAPS J , vol.9 , Issue.2
    • Fahmy, T.M.1    Fong, P.M.2    Park, J.3    Constable, T.4    Saltzman, W.M.5
  • 21
    • 0035478442 scopus 로고    scopus 로고
    • Trancytosis of nanoparticles and dendrimers delivery system: Evolving vistar
    • Florence AT, Hussain N. 2001. Trancytosis of nanoparticles and dendrimers delivery system: Evolving vistar. Adv Drug Deliv Rev 50:S69-89.
    • (2001) Adv Drug Deliv Rev , vol.50
    • Florence, A.T.1    Hussain, N.2
  • 22
    • 34547655840 scopus 로고    scopus 로고
    • Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration
    • Gao X, Wu B, Zhang Q, Chen J, Zhu J, Zhang W, Rong Z, Chen H, Jiang X. 2007. Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration. J Control Release 121:156-167.
    • (2007) J Control Release , vol.121 , pp. 156-167
    • Gao, X.1    Wu, B.2    Zhang, Q.3    Chen, J.4    Zhu, J.5    Zhang, W.6    Rong, Z.7    Chen, H.8    Jiang, X.9
  • 23
    • 0034691645 scopus 로고    scopus 로고
    • Biodistribution of fluoresceinated dex-tran using novel nanoparticles evading reticuloendothelial system
    • Gaur U, Sahoo SK. 2000. Biodistribution of fluoresceinated dex-tran using novel nanoparticles evading reticuloendothelial system. Int J Pharm 202:1-10.
    • (2000) Int J Pharm , vol.202 , pp. 1-10
    • Gaur, U.1    Sahoo, S.K.2
  • 24
    • 42649106878 scopus 로고    scopus 로고
    • Nanoparticles: Characteristics, mechanisms of action, and tox-icity in pulmonary drug delivery-a review
    • Gill S, Lobenberg R, Ku T, Azarmi S, Roa W, Prenner EJ. 2007. Nanoparticles: Characteristics, mechanisms of action, and tox-icity in pulmonary drug delivery-a review. J Biomed Nano-technol 3:107-119.
    • (2007) J Biomed Nano-technol , vol.3 , pp. 107-119
    • Gill, S.1    Lobenberg, R.2    Ku, T.3    Azarmi, S.4    Roa, W.5    Prenner, E.J.6
  • 25
    • 36749087493 scopus 로고    scopus 로고
    • Development and validation of a stability indicating RP-LC method for determination of Imatinib Mesylate
    • Girish B, Kollipara S, Kolachina V, Saha R. 2007. Development and validation of a stability indicating RP-LC method for determination of Imatinib Mesylate. Chromatographia 66:859-866.
    • (2007) Chromatographia , vol.66 , pp. 859-866
    • Girish, B.1    Kollipara, S.2    Kolachina, V.3    Saha, R.4
  • 26
    • 0042999388 scopus 로고    scopus 로고
    • Pegaspargase: A review of clinical studies
    • Graham ML. 2003. Pegaspargase: A review of clinical studies. Adv Drug Deliv Rev 55:1293-1302.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 1293-1302
    • Graham, M.L.1
  • 27
    • 0033964139 scopus 로고    scopus 로고
    • Nanosuspension of poorly soluble drugs-reproducibility of small scale production
    • Grau MJ, Kayser O, Muller RH. 2000. Nanosuspension of poorly soluble drugs-reproducibility of small scale production. Int J Pharm 196:155-157.
    • (2000) Int J Pharm , vol.196 , pp. 155-157
    • Grau, M.J.1    Kayser, O.2    Muller, R.H.3
  • 29
    • 0037362655 scopus 로고    scopus 로고
    • Effect of pegylation on pharmaceuticals
    • Harris JM, Chess RB. 2003. Effect of pegylation on pharmaceuticals. Nat Rev Drug Discov 2:214-221.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 214-221
    • Harris, J.M.1    Chess, R.B.2
  • 30
    • 63949084469 scopus 로고    scopus 로고
    • Selective adhesion of nanoparticles to inflamed tissue in gastric ulcers
    • Hasani S, Pellequer Y, Lamprechi A. 2009. Selective adhesion of nanoparticles to inflamed tissue in gastric ulcers. Pharm Res 26 (5):1149-1154.
    • (2009) Pharm Res , vol.26 , Issue.5 , pp. 1149-1154
    • Hasani, S.1    Pellequer, Y.2    Lamprechi, A.3
  • 33
    • 0026583386 scopus 로고
    • Influence of supersatura-tion on the pharmacodynamic effect of bupranolol after dermal administration using microemulsion as vehicle
    • Kemken J, Ziegler A, Muller BW. 1992. Influence of supersatura-tion on the pharmacodynamic effect of bupranolol after dermal administration using microemulsion as vehicle. Pharm Res 9:554-558.
    • (1992) Pharm Res , vol.9 , pp. 554-558
    • Kemken, J.1    Ziegler, A.2    Muller, B.W.3
  • 35
    • 0035937527 scopus 로고    scopus 로고
    • Liposomes with phos-phatidylethanol as a carrier for oral delivery of insulin: Studies in the rat
    • Kisel MA, Perez-soler R, Cruz ME. 2001. Liposomes with phos-phatidylethanol as a carrier for oral delivery of insulin: Studies in the rat. Int J Pharm 216:105-114.
    • (2001) Int J Pharm , vol.216 , pp. 105-114
    • Kisel, M.A.1    Perez-Soler, R.2    Cruz, M.E.3
  • 36
    • 22644441692 scopus 로고    scopus 로고
    • Gelatin nanoparticles as a new and simple gene delivery system
    • Klaus Z, Julia K, Ernst W, Conrad C. 2004. Gelatin nanoparticles as a new and simple gene delivery system. J Pharm Pharmaceut Sci 7(4):22-28.
    • (2004) J Pharm Pharmaceut Sci , vol.7 , Issue.4 , pp. 22-28
    • Klaus, Z.1    Julia, K.2    Ernst, W.3    Conrad, C.4
  • 37
    • 77956934839 scopus 로고    scopus 로고
    • Application of rotatable central composite design in the preparation and optimization of poly (lactic-co-glycolic acid) nanoparticles for controlled delivery of paclitaxel
    • Posted online on June 14, 2010, doi: 10.3109103639045.2010.487263
    • Kollipara S, Girish B, Snehalatha M, Saha RN. 2010. Application of rotatable central composite design in the preparation and optimization of poly (lactic-co-glycolic acid) nanoparticles for controlled delivery of paclitaxel. Drug Dev Ind Pharm (Posted online on June 14, 2010, doi: 10.3109103639045.2010. 487263).
    • (2010) Drug Dev Ind Pharm
    • Kollipara, S.1    Girish, B.2    Snehalatha, M.3    Saha, R.N.4
  • 38
    • 34547905035 scopus 로고    scopus 로고
    • Lipid nanoparticles for improved topical application of drug for skin diseases
    • Korting MS, Mehnert W, Korting HS. 2007. Lipid nanoparticles for improved topical application of drug for skin diseases. Adv Drug Deliv Rev 59:427-443.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 427-443
    • Korting, M.S.1    Mehnert, W.2    Korting, H.S.3
  • 39
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate system for brain delivery of drug
    • Kreuter J. 2001. Nanoparticulate system for brain delivery of drug. Adv Drug Deliv Rev 47:65-81.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 65-81
    • Kreuter, J.1
  • 40
    • 0034872426 scopus 로고    scopus 로고
    • Size dependent targeting of micro-and nanoparticles carriers to the inflamed colonic mucosa
    • Lamprecht A, Schafer U, Lehr CM. 2001. Size dependent targeting of micro-and nanoparticles carriers to the inflamed colonic mucosa. Pharm Res 18:788-793.
    • (2001) Pharm Res , vol.18 , pp. 788-793
    • Lamprecht, A.1    Schafer, U.2    Lehr, C.M.3
  • 41
    • 0032580354 scopus 로고    scopus 로고
    • Drug delivery and targeting
    • Langer R. 1998. Drug delivery and targeting. Nature 392:5-10.
    • (1998) Nature , vol.392 , pp. 5-10
    • Langer, R.1
  • 42
    • 33847256524 scopus 로고    scopus 로고
    • A review of the formation and classification of amphiphilic block copolymer nanoparticulate structure: Micelles, nanospheres, nanocapsules and polymersomes
    • Letchford K, Burt H. 2007. A review of the formation and classification of amphiphilic block copolymer nanoparticulate structure: Micelles, nanospheres, nanocapsules and polymersomes. Eur J Pharm Biopharm 65:259-269.
    • (2007) Eur J Pharm Biopharm , vol.65 , pp. 259-269
    • Letchford, K.1    Burt, H.2
  • 43
    • 0001985859 scopus 로고    scopus 로고
    • Clinical relevance of the molecular mechanisms of resistance to anti-cancer drugs
    • Links M, Brown R. 1999. Clinical relevance of the molecular mechanisms of resistance to anti-cancer drugs. Expert Rev Anticancer Ther 1999:1-21.
    • (1999) Expert Rev Anticancer Ther , vol.1999 , pp. 1-21
    • Links, M.1    Brown, R.2
  • 44
    • 0035816204 scopus 로고    scopus 로고
    • Mechanism of tumor-targeted delivery of macromolecular drug including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
    • Maeda H, Sawa T, Konno T. 2001. Mechanism of tumor-targeted delivery of macromolecular drug including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J Control Release 74:47-61.
    • (2001) J Control Release , vol.74 , pp. 47-61
    • Maeda, H.1    Sawa, T.2    Konno, T.3
  • 45
    • 60749108001 scopus 로고    scopus 로고
    • Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
    • Maeda H, Bharate GY, Daruwalla J. 2009. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur J Pharm Biopharm 71:409-419.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 409-419
    • Maeda, H.1    Bharate, G.Y.2    Daruwalla, J.3
  • 46
    • 12344337457 scopus 로고    scopus 로고
    • PLGA nanoparticles containing praziquantel: Effect of formulation variables on size distribution
    • Mainardes RM, Evangelista RC. 2005. PLGA nanoparticles containing praziquantel: Effect of formulation variables on size distribution. Int J Pharm 290:137-144.
    • (2005) Int J Pharm , vol.290 , pp. 137-144
    • Mainardes, R.M.1    Evangelista, R.C.2
  • 47
    • 0021168136 scopus 로고
    • Patho-genesis of serratial infection: Activation of the Hageman facto-perkallikerin cascade by serratial protease
    • Matsumoto K, Yamamoto T, Kamata R, Marda H. 1984. Patho-genesis of serratial infection: Activation of the Hageman facto-perkallikerin cascade by serratial protease. J Biochem 96: 739-749.
    • (1984) J Biochem , vol.96 , pp. 739-749
    • Matsumoto, K.1    Yamamoto, T.2    Kamata, R.3    Marda, H.4
  • 49
    • 16244418685 scopus 로고    scopus 로고
    • Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium
    • Miller NS, Johnston TP. 2005. Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium. Int J Pharm 294:201-216.
    • (2005) Int J Pharm , vol.294 , pp. 201-216
    • Miller, N.S.1    Johnston, T.P.2
  • 50
    • 22844451300 scopus 로고    scopus 로고
    • The human cancer genome project-one more misstep in the war on cancer
    • Miklos GL. 2005. The human cancer genome project-one more misstep in the war on cancer. Nat Biotechnol 23: 535-537.
    • (2005) Nat Biotechnol , vol.23 , pp. 535-537
    • Miklos, G.L.1
  • 51
    • 0141764822 scopus 로고    scopus 로고
    • Poly n-butyl cyanoac-rylate (PNBCA) nanocapsules as a carrier for NSAIDs. in vitro release and in vivo skin penetration
    • Miyazaki S, Takahashi A, Kubo W. 2003. Poly n-butyl cyanoac-rylate (PNBCA) nanocapsules as a carrier for NSAIDs: In vitro release and in vivo skin penetration. J Pharm Pharmaceut Sci 6 (2):240-245.
    • (2003) J Pharm Pharmaceut Sci , vol.6 , Issue.2 , pp. 240-245
    • Miyazaki, S.1    Takahashi, A.2    Kubo, W.3
  • 52
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: Theory to practice
    • Moghimi SM, Hunter AC, Murray JC. 2001. Long-circulating and target-specific nanoparticles: Theory to practice. Pharmacol Rev 53:283-218.
    • (2001) Pharmacol Rev , vol.53 , pp. 283-218
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 53
    • 0344083669 scopus 로고    scopus 로고
    • PLGA/TPGS nanoparticles for controlled release of paclitaxel: Effect of the emulsion and drug loading ratio
    • Mu L, Feng SS. 2003. PLGA/TPGS nanoparticles for controlled release of paclitaxel: Effect of the emulsion and drug loading ratio. Pharm Res 20:1864-1872.
    • (2003) Pharm Res , vol.20 , pp. 1864-1872
    • Mu, L.1    Feng, S.S.2
  • 54
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nano-particles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatolodical preparation
    • Muller RH, Radtka M, Wilsing SA. 2002. Solid lipid nano-particles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatolodical preparation. Adv Drug Deliv Rev 1:S131-155.
    • (2002) Adv Drug Deliv Rev , vol.1
    • Muller, R.H.1    Radtka, M.2    Wilsing, S.A.3
  • 56
    • 0025798935 scopus 로고
    • Microemulsions as topical delivery vehicles: In-vitro transdermal studies of a model hydro-philic drug
    • Osborne DW, Ward AJ, Neil KJ. 1991. Microemulsions as topical delivery vehicles: In-vitro transdermal studies of a model hydro-philic drug. J Pharm Pharmacol 43:450-454.
    • (1991) J Pharm Pharmacol , vol.43 , pp. 450-454
    • Osborne, D.W.1    Ward, A.J.2    Neil, K.J.3
  • 57
    • 0037462992 scopus 로고    scopus 로고
    • PEGylated nanoparticles or biological and pharmaceutical applications
    • Otsuka H, Nagasaki Y, Kataoka K. 2003. PEGylated nanoparticles or biological and pharmaceutical applications. Adv Drug Deliv Rev 55:403-419.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 403-419
    • Otsuka, H.1    Nagasaki, Y.2    Kataoka, K.3
  • 58
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution and pharmacokinetics of polymer nanoparticles
    • Owens De III, Peppas NA. 2006. Opsonization, biodistribution and pharmacokinetics of polymer nanoparticles. Int J Pharm 307:93-102.
    • (2006) Int J Pharm , vol.307 , pp. 93-102
    • Owens Iii, D.E.1    Peppas, N.A.2
  • 59
    • 0036324712 scopus 로고    scopus 로고
    • Rapid endo-lysosomal escape of poly (D, L-lactide-co-glyco-lide) nanoparticles: Implications for drug and gene delivery
    • Panyam J, Zhou WZ, Prabha S, Sahoo SK, Labhasetwar V. 2002. Rapid endo-lysosomal escape of poly (D, L-lactide-co-glyco-lide) nanoparticles: Implications for drug and gene delivery. FASEB J 16:1217-1226.
    • (2002) FASEB J , vol.16 , pp. 1217-1226
    • Panyam, J.1    Zhou, W.Z.2    Prabha, S.3    Sahoo, S.K.4    Labhasetwar, V.5
  • 60
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • Panyam J, Labhasetwar V. 2003a. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 55:329-347.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 329-347
    • Panyam, J.1    Labhasetwar, V.2
  • 61
    • 0037331856 scopus 로고    scopus 로고
    • Dynamics of endocytosis and exocytosis of poly (D, L-lactide-co- glycolide) nano-particles in vascular smooth muscle cells
    • Panyam J, Labhasetwar V. 2003b. Dynamics of endocytosis and exocytosis of poly (D, L-lactide-co-glycolide) nano-particles in vascular smooth muscle cells. Pharm Res 20: 110-118.
    • (2003) Pharm Res , vol.20 , pp. 110-118
    • Panyam, J.1    Labhasetwar, V.2
  • 62
    • 33845348221 scopus 로고    scopus 로고
    • Development and evaluation of topical formulation containing solid lipid nanoparticles of vitamin A
    • Pople PV, Singh KK. 2006. Development and evaluation of topical formulation containing solid lipid nanoparticles of vitamin A. AAPS PharmSciTech 7(4):E1-7.
    • (2006) AAPS PharmSciTech , vol.7 , Issue.4
    • Pople, P.V.1    Singh, K.K.2
  • 63
    • 0033790335 scopus 로고    scopus 로고
    • Freeze-drying of polycaprolactone and poly (D,L-lactic-glycolic) nano-particles induce minor particle size changes affecting the oral pharmacokinetic of loaded drugs
    • Saez A, Guzman M, Molpeceres J, Aberturas MR. 2000. Freeze-drying of polycaprolactone and poly (D,L-lactic-glycolic) nano-particles induce minor particle size changes affecting the oral pharmacokinetic of loaded drugs. Eur J Pharm Biopharm 50:379-387.
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 379-387
    • Saez, A.1    Guzman, M.2    Molpeceres, J.3    Aberturas, M.R.4
  • 64
    • 33645999705 scopus 로고    scopus 로고
    • Chitosan nanoparticles as a potential drug delivery system for the ocular surface: Toxicity, uptake mechanism and in vivo tolerance
    • Salamanca AE, Diebold Y, Calonge M, Vazquez CG, Callejo S, Vila A, Aloso MJ. 2006. Chitosan nanoparticles as a potential drug delivery system for the ocular surface: Toxicity, uptake mechanism and in vivo tolerance. Invest. Ophthalmol Vis Sci 47 (4):1416-1425.
    • (2006) Invest. Ophthalmol Vis Sci , vol.47 , Issue.4 , pp. 1416-1425
    • Salamanca, A.E.1    Diebold, Y.2    Calonge, M.3    Vazquez, C.G.4    Callejo, S.5    Vila, A.6    Aloso, M.J.7
  • 65
    • 78049339782 scopus 로고    scopus 로고
    • A new, simple HPLC method for estimation of paclitaxel in micro-volume rat plasma
    • Sekar V, Selladurai ST, Saha RN. 2009. A new, simple HPLC method for estimation of paclitaxel in micro-volume rat plasma. AAPS J 11(S2):1953.
    • (2009) AAPS J , vol.11 , Issue.S2 , pp. 1953
    • Sekar, V.1    Selladurai, S.T.2    Saha, R.N.3
  • 67
    • 0035559193 scopus 로고    scopus 로고
    • Molecular and pharmacological strategies to overcome multidrug resistance
    • Shabbits JA, Krishna R, Mayer LD. 2001. Molecular and pharmacological strategies to overcome multidrug resistance. Expert Rev Anticancer Ther 1:585-594.
    • (2001) Expert Rev Anticancer Ther , vol.1 , pp. 585-594
    • Shabbits, J.A.1    Krishna, R.2    Mayer, L.D.3
  • 68
    • 20044382269 scopus 로고    scopus 로고
    • Effect of particle size of nanospheres and microspheres on the cellular-association and cytotoxicity of paclitaxel in 4T1 cells
    • Sinjan De, Miller DW, Robinson DH. 2005. Effect of particle size of nanospheres and microspheres on the cellular-association and cytotoxicity of paclitaxel in 4T1 cells. Pharm Res 22:766-775.
    • (2005) Pharm Res , vol.22 , pp. 766-775
    • Sinjan De Miller, D.W.1    Robinson, D.H.2
  • 69
    • 78651156947 scopus 로고
    • Experimental evaluation of potential anticancer agents XIII: On the criteria and kinetics associated with 'curability' of experimental leukemia
    • Skipper H, Schabel J, Wilcox W. 1964. Experimental evaluation of potential anticancer agents XIII: On the criteria and kinetics associated with 'curability' of experimental leukemia. Cancer Treat Rep 55:1-111.
    • (1964) Cancer Treat Rep , vol.55 , pp. 1-111
    • Skipper, H.1    Schabel, J.2    Wilcox, W.3
  • 70
    • 50849097566 scopus 로고    scopus 로고
    • EP loaded PLGA and PCL nanoparticles II: Biodistribution and pharmacokinetic after radiolabeling with Tc-99m
    • Snehalatha M, Venugopal K, Saha RN, Babbar AK, Sharma RK. 2008a. EP loaded PLGA and PCL nanoparticles II: Biodistribution and pharmacokinetic after radiolabeling with Tc-99m. Drug Deliv 15:277-287.
    • (2008) Drug Deliv , vol.15 , pp. 277-287
    • Snehalatha, M.1    Venugopal, K.2    Saha, R.N.3    Babbar, A.K.4    Sharma, R.K.5
  • 71
    • 84922520498 scopus 로고    scopus 로고
    • Etoposide-loaded PLGA and PCL nanoparticles I: Preparation and effect of formulation variables
    • Snehalatha M, Venugopal K, Saha RN. 2008b. Etoposide-loaded PLGA and PCL nanoparticles I: Preparation and effect of formulation variables. Drug Deliv 15:267-275.
    • (2008) Drug Deliv , vol.15 , pp. 267-275
    • Snehalatha, M.1    Venugopal, K.2    Saha, R.N.3
  • 72
    • 34547216961 scopus 로고    scopus 로고
    • Nanofabricated particles for engineered drug therapies: A preliminary biodistribution study of PRINT nanoparticles
    • Stephanie EAG, Patrick DP, Jin L, Ji G, Moo JC, De Simone JM. 2007. Nanofabricated particles for engineered drug therapies: A preliminary biodistribution study of PRINT nanoparticles. J Control Release 121:10-18.
    • (2007) J Control Release , vol.121 , pp. 10-18
    • Stephanie, E.A.G.1    Patrick, D.P.2    Jin, L.3    Ji, G.4    Moo, J.C.5    De Simone, J.M.6
  • 75
    • 0035478758 scopus 로고    scopus 로고
    • Chitosan and its derivatives as intestinal absorption enhancers
    • Thanou M, Verhoef JC, Junginger HE. 2001. Chitosan and its derivatives as intestinal absorption enhancers. Adv Drug Deliv Rev 50:S91-101.
    • (2001) Adv Drug Deliv Rev , vol.50
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 76
    • 34249327294 scopus 로고    scopus 로고
    • Targeted pharmaceutical nanocarriers for cancer theraphy and imaging
    • Torchilin V. 2007. Targeted pharmaceutical nanocarriers for cancer theraphy and imaging. AAPS J 9(2):E128-147.
    • (2007) AAPS J , vol.9 , Issue.2
    • Torchilin, V.1
  • 78
    • 0032806764 scopus 로고    scopus 로고
    • Influence of phase transformation on indo-methacin release from microemulsion
    • Trotta M. 1999. Influence of phase transformation on indo-methacin release from microemulsion. J Control Rel 60: 399-405.
    • (1999) J Control Rel , vol.60 , pp. 399-405
    • Trotta, M.1
  • 80
    • 36749067955 scopus 로고    scopus 로고
    • Design aspects of poly (alkylcyanoacrylate) nanoparticles for drug delivery
    • Vauthier C, Labarre D, Ponchel G. 2007. Design aspects of poly (alkylcyanoacrylate) nanoparticles for drug delivery. J Drug Targeting 15:641-663.
    • (2007) J Drug Targeting , vol.15 , pp. 641-663
    • Vauthier, C.1    Labarre, D.2    Ponchel, G.3
  • 81
    • 63949086707 scopus 로고    scopus 로고
    • Method for the preparation and manufacture of polymeric nanoparticles
    • Vauthier C, Bouchemal K. 2008. Method for the preparation and manufacture of polymeric nanoparticles. Pharm Res 26: 1025-1058.
    • (2008) Pharm Res , vol.26 , pp. 1025-1058
    • Vauthier, C.1    Bouchemal, K.2
  • 82
    • 43249097189 scopus 로고    scopus 로고
    • How to concentrate nanoparticles and avoid aggregation?
    • Vauthier C, Cabane B, Labarre D. 2008. How to concentrate nanoparticles and avoid aggregation? Eur J Pharm Biopharm 69:466-475.
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 466-475
    • Vauthier, C.1    Cabane, B.2    Labarre, D.3
  • 84
    • 50149094833 scopus 로고    scopus 로고
    • Targeted delivery of tacrine into the brain with polysorbates 80-coated poly (n-butylcyanoa-crylate) nanoparticles
    • Wilson B, Samanta MK, Santhi K, Sampath KKP, Paramakrishnan N, Suresh B. 2008. Targeted delivery of tacrine into the brain with polysorbates 80-coated poly (n-butylcyanoa-crylate) nanoparticles. Eur J Pharm Biopharm 70:75-84.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 75-84
    • Wilson, B.1    Samanta, M.K.2    Santhi, K.3    Sampath, K.K.P.4    Paramakrishnan, N.5    Suresh, B.6
  • 85
    • 49749102777 scopus 로고    scopus 로고
    • Distribution of an i.v. injectable nimodipine nanosuspension in mice
    • Xiong R, Lu W, Yue P, Xu R, Li J, Chen T, Wang P. 2008. Distribution of an i.v. injectable nimodipine nanosuspension in mice. J Pharm Pharmacol 60:1155-1159.
    • (2008) J Pharm Pharmacol , vol.60 , pp. 1155-1159
    • Xiong, R.1    Lu, W.2    Yue, P.3    Xu, R.4    Li, J.5    Chen, T.6    Wang, P.7
  • 88
    • 16244376470 scopus 로고    scopus 로고
    • Preparation and characterization of poly-caprolactone nanoparticles containing griseofulvin
    • Zili Z, Sfar S, Fessi H. 2005. Preparation and characterization of poly-caprolactone nanoparticles containing griseofulvin. Int J Pharm 294:261-267.
    • (2005) Int J Pharm , vol.294 , pp. 261-267
    • Zili, Z.1    Sfar, S.2    Fessi, H.3


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