High molecular weight hyaluronic acid relieved joint pain and prevented the progression of cartilage degeneration in a rabbit osteoarthritis model after onset of arthritis

Modern Rheumatology

Volumn 20, Issue 5, 2010, Pages 432-438

  Hashizume, Misato ^a   Koike, Nobuo ^a   Yoshida, Hiroto ^a   Suzuki, Miho ^a   Mihara, Masahiko ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

High molecular hyaluronic acid; NSAID; Osteoarthritis; Rabbit osteoarthritis model

Indexed keywords

HIGH MOLECULAR WEIGHT HYALURONIC ACID; HYALURONIC ACID; LOXOPROFEN; MATRIX METALLOPROTEINASE; PROSTAGLANDIN E2; SUVENYL; UNCLASSIFIED DRUG;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRALGIA; ARTICLE; CARTILAGE DEGENERATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE COURSE; MALE; MENISCECTOMY; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANALGESICS; ANIMALS; ANIMALS, INBRED STRAINS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARTILAGE, ARTICULAR; DINOPROSTONE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HYALURONIC ACID; MALE; MATRIX METALLOPROTEINASES; MOLECULAR WEIGHT; OSTEOARTHRITIS; PAIN; PAIN MEASUREMENT; PHENYLPROPIONATES; RABBITS; STIFLE; SYNOVIAL FLUID;

EID: 78049321682     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-010-0299-1     Document Type: Article

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