Quercetin enhances human α7 nicotinic acetylcholine receptor-mediated ion current through interactions with Ca 2+ binding sites

Molecules and Cells

Volumn 30, Issue 3, 2010, Pages 245-253

  Lee, Byung Hwan ^a   Choi, Sun Hye ^a   Shin, Tae Joon ^a   Pyo, Mi Kyung ^a   Hwang, Sung Hee ^a   Kim, Bo Ra ^a   Lee, Sang Mok ^a   Lee, Jun Ho ^b   Kim, Hyoung Chun ^c   Park, Hye Young ^d   Rhim, Hyewhon ^d   Nah, Seung Yeol ^a  

^a Konkuk University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Kangwon National University   (South Korea)

^d Korea Institute of Science and Technology   (South Korea)

Author keywords

7 nAChR; Ca 2+; Ca 2+ binding site; flavonoids; quercetin

Indexed keywords

ACETYLCHOLINE; BARIUM ION; BUNGAROTOXIN RECEPTOR; CALCIUM ION; COMPLEMENTARY DNA; COMPLEMENTARY RNA; GLUTAMIC ACID; GLUTAMINE; QUERCETIN; TYROSINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM BINDING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; EXTRACELLULAR CALCIUM; HETEROLOGOUS EXPRESSION; HUMAN; ION CURRENT; MICROINJECTION; NONHUMAN; OOCYTE; PROTEIN FUNCTION; PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; VOLTAGE CLAMP; XENOPUS;

ANIMALS; BINDING SITES; BRAIN; CALCIUM; CLONING, MOLECULAR; HUMANS; ION TRANSPORT; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; QUERCETIN; RECEPTORS, NICOTINIC; TRANSGENES; XENOPUS;

EID: 78049318379     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-010-0117-9     Document Type: Article

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