Use of Lugol's iodine in oral cancer diagnosis: An overview

Oral Oncology

Volumn 46, Issue 11, 2010, Pages 811-813

  Petruzzi, Massimo ^a   Lucchese, Alberta ^b   Baldoni, Edoardo ^c   Grassi, Felice Roberto ^a   Serpico, Rosario ^d  

^a UNIVERSITY OF BARI   (Italy)

^b Private Practice   (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

^d SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Dysplasia; Lugol's iodine; Oral cancer; Vital dye; Vital staining

Indexed keywords

LUGOL;

CANCER CLASSIFICATION; CANCER DIAGNOSIS; CLINICAL PRACTICE; COST BENEFIT ANALYSIS; DYSPLASIA; EARLY DIAGNOSIS; HUMAN; MOUTH CANCER; PATIENT SAFETY; PRIORITY JOURNAL; REVIEW;

CARCINOMA, SQUAMOUS CELL; COLORING AGENTS; EARLY DETECTION OF CANCER; FEMALE; HUMANS; IODIDES; MALE; MOUTH NEOPLASMS; STAINING AND LABELING;

EID: 78049316702     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2010.07.013     Document Type: Review

References (19)

1. M.B. Fennerty Tissue staining Gastrointest Endosc Clin N Am 4 1994 297 311
2. S. Silverman Jr., J. Barbosa, and G. Kearns Ultrastructural and histochemical localization of glycogen in human normal and hyperkeratotic oral epithelium Arch Oral Biol 16 4 1971 423 434
3. H. Ashrafian Cancer's sweet tooth: the Janus effect of glucose metabolism in tumorigenesis Lancet 367 9510 2006 618 621
4. W. Schiller Early diagnosis of carcinoma of the cervix Surg Gynecol Obstet 56 1933 210 222
5. G.J. Brodmerkel Schiller's test: an aid in esophagoscopic diagnosis Gastroenterology 60 1971 813 818
6. H. Inoue, J.F. Rey, and C.J. Lightdale Lugol chromoendoscopy for oesophageal squamous cell cancer Endoscopy 33 2001 75 79
7. K. Sugimachi, K. Kitamura, and K. Baba Endoscopic diagnosis of early carcinoma of the esophagus using Lugol's solution Gastrointest Endosc 38 1992 657 661
8. R. Sankaranarayanan, R. Wesley, S. Thara, N. Dhakad, B. Chandralekha, and P. Sebastian Test characteristics of visual inspection with 4% acetic acid (VIA) and Lugol's iodine (VILI) in cervical cancer screening in Kerala, India Int J Cancer 106 3 2003 404 408
9. H. Shiozaki, H. Tahara, K. Kobayashi, H. Yano, S. Tamura, and H. Imamoto Endoscopic screening of early esophageal cancer with the Lugol dye method in patients with head and neck cancers Cancer 66 10 1990 2068 2071
10. J.B. Epstein, C. Scully, and J. Spinelli Toluidine blue and Lugol's iodine application in the assessment of oral malignant disease and lesions at risk of malignancy J Oral Pathol Med 21 4 1992 160 163
11. E.M. Chisholm, S.R. Williams, J.W. Leung, S.C. Chung, C.A. Van Hasselt, and A.K. Li Lugol's iodine dye-enhanced endoscopy in patients with cancer of the oesophagus and head and neck Eur J Surg Oncol 18 6 1992 550 552
12. H. Kurita, and K. Kurashina Vital staining with iodine solution in delineating the border of oral dysplastic lesions Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81 3 1996 275 280
13. Y. Yajima, H. Noma, Y. Furuya, T. Nomura, T. Yamauchi, and K. Kasahara Quantification of telomerase activity of regions unstained with iodine solution that surround oral squamous cell carcinoma Oral Oncol 40 3 2004 314 320
14. K. Yokoo, H. Noma, T. Inoue, S. Hashimoto, and M. Shimono Cell proliferation and tumour suppressor gene expression in iodine unstained area surrounding oral squamous cell carcinoma Int J Oral Maxillofac Surg 33 1 2004 75 83
15. K. Maeda, T. Suzuki, Y. Ooyama, K. Nakakuki, M. Yamashiro, and N. Okada Colorimetric analysis of unstained lesions surrounding oral squamous cell carcinomas and oral potentially malignant disorders using iodine Int J Oral Maxillofac Surg 39 5 2010 486 492
16. K. Maeda, M. Yamashiro, Y. Michi, T. Suzuki, Y. Ohyama, and N. Okada Effective staining method with iodine for leukoplakia and lesions surrounding squamous cell carcinomas of the tongue assessed by colorimetric analysis J Med Dent Sci 56 4 2009 123 130
17. J. McMahon, J.C. Devine, J.A. McCaul, D.R. McLellan, and A. Farrow Use of Lugol's iodine in the resection of oral and oropharyngeal squamous cell carcinoma Br J Oral Maxillofac Surg 48 2 2010 84 87
18. D.P. Slaughter, H.W. Southwick, and W. Smejkal Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin Cancer 6 5 1953 963 968
19. O. Kujan, A.M. Glenny, J. Duxbury, N. Thakker, and P. Sloan Evaluation of screening strategies for improving oral cancer mortality: a Cochrane systematic review J Dent Educ 69 2 2005 255 265