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Volumn 56, Issue 5, 2010, Pages 496-506

RNA interference in ageing research - A mini-review

Author keywords

Ageing; Life span; Model organisms; RNA interference; Time course analysis

Indexed keywords

AGING; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ASSOCIATION; MOLECULAR LIBRARY; MUTANT; NONHUMAN; PRIORITY JOURNAL; RESEARCH; RNA INTERFERENCE; SHORT SURVEY; TECHNOLOGY;

EID: 78049312236     PISSN: 0304324X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000277626     Document Type: Short Survey
Times cited : (12)

References (64)
  • 1
    • 62249117077 scopus 로고    scopus 로고
    • The evolutionary theories of aging revisited - A mini-review
    • Ljubuncic P, Reznick AZ: The evolutionary theories of aging revisited - a mini-review. Gerontology 2009; 55: 205-216.
    • (2009) Gerontology , vol.55 , pp. 205-216
    • Ljubuncic, P.1    Reznick, A.Z.2
  • 3
    • 0000055057 scopus 로고
    • Pleiotropy, natural selection, and the evolution of senescence
    • Williams GC: Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957; 11: 398-411.
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 4
    • 78049318710 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • Friedman DB, Johnson TE: A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 1988; 75: 86.
    • (1988) Genetics , vol.75 , pp. 86
    • Friedman, D.B.1    Johnson, T.E.2
  • 6
    • 38148999355 scopus 로고    scopus 로고
    • Let me count the ways: Mechanisms of gene regulation by miRNAs and siRNAs
    • Wu L, Belasco JG: Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs. Mol Cell 2008; 29: 1-7.
    • (2008) Mol Cell , vol.29 , pp. 1-7
    • Wu, L.1    Belasco, J.G.2
  • 7
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans . Nature 1998; 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 9
    • 33644682382 scopus 로고    scopus 로고
    • An introduction to RNAmediated gene silencing
    • Geanacopoulos M: An introduction to RNAmediated gene silencing. Sci Prog 2005; 88: 49-69.
    • (2005) Sci Prog , vol.88 , pp. 49-69
    • Geanacopoulos, M.1
  • 10
    • 23144441141 scopus 로고    scopus 로고
    • E-RNAi: A web application to design optimized RNAi constructs
    • Arziman Z, Horn T, Boutros M: E-RNAi: a web application to design optimized RNAi constructs. Nucleic Acids Res 2005; 33: W582-W588.
    • (2005) Nucleic Acids Res , vol.33
    • Arziman, Z.1    Horn, T.2    Boutros, M.3
  • 11
    • 68149136449 scopus 로고    scopus 로고
    • Converging pathways in lifespan regulation
    • Narasimhan SD, Yen K, Tissenbaum HA: Converging pathways in lifespan regulation. Curr Biol 2009; 19: 657-666.
    • (2009) Curr Biol , vol.19 , pp. 657-666
    • Narasimhan, S.D.1    Yen, K.2    Tissenbaum, H.A.3
  • 14
    • 40549127471 scopus 로고    scopus 로고
    • Drosophila lifespan control by dietary restriction independent of insulin-like signalling
    • Min KJ, Yamamoto R, Buch S, Pankratz M, Tatar M: Drosophila lifespan control by dietary restriction independent of insulin-like signalling. Aging Cell 2008; 7: 199-206.
    • (2008) Aging Cell , vol.7 , pp. 199-206
    • Min, K.J.1    Yamamoto, R.2    Buch, S.3    Pankratz, M.4    Tatar, M.5
  • 15
    • 0037059057 scopus 로고    scopus 로고
    • RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress
    • Kirby K, Hu J, Hilliker AJ, Phillips JP: RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress. Proc Natl Acad Sci USA 2002; 99: 16162-16167.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16162-16167
    • Kirby, K.1    Hu, J.2    Hilliker, A.J.3    Phillips, J.P.4
  • 16
    • 0346100684 scopus 로고    scopus 로고
    • A Sod2 null mutation confers severely reduced adult life span in Drosophila
    • Duttaroy A, Paul A, Kundu M, Belton A: A Sod2 null mutation confers severely reduced adult life span in Drosophila . Genetics 2003; 165: 2295-2299.
    • (2003) Genetics , vol.165 , pp. 2295-2299
    • Duttaroy, A.1    Paul, A.2    Kundu, M.3    Belton, A.4
  • 17
    • 26444536278 scopus 로고    scopus 로고
    • C. elegans ortholog of mammalian Ku70 interacts with insulin-like signalling to modulate stress resistance and life span
    • McColl G, Vantipalli MC, Lithgow GJ: C. elegans ortholog of mammalian Ku70 interacts with insulin-like signalling to modulate stress resistance and life span. FASEB J 2005; 19: 1716-1718.
    • (2005) FASEB J , vol.19 , pp. 1716-1718
    • McColl, G.1    Vantipalli, M.C.2    Lithgow, G.J.3
  • 18
    • 33845476497 scopus 로고    scopus 로고
    • Involvement of Drosophila Sir2 - Like genes in the regulation of life span
    • Kusama S, Ueda R, Suda T, Nishihara S, Matsuura ET: Involvement of Drosophila Sir2 - like genes in the regulation of life span. Genes Genet Syst 2006; 81: 341-348.
    • (2006) Genes Genet Syst , vol.81 , pp. 341-348
    • Kusama, S.1    Ueda, R.2    Suda, T.3    Nishihara, S.4    Matsuura, E.T.5
  • 19
    • 35648947912 scopus 로고    scopus 로고
    • Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
    • Rea SL, Ventura N, Johnson TE: Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans . PLoS Biol 2007; 5: 1-18.
    • (2007) PLoS Biol , vol.5 , pp. 1-18
    • Rea, S.L.1    Ventura, N.2    Johnson, T.E.3
  • 20
    • 3042776333 scopus 로고    scopus 로고
    • A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint
    • Lee SJ, Yook JS, Han SM, Koo HS: A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint. Development 2004; 131: 2565-2575.
    • (2004) Development , vol.131 , pp. 2565-2575
    • Lee, S.J.1    Yook, J.S.2    Han, S.M.3    Koo, H.S.4
  • 21
    • 33644830913 scopus 로고    scopus 로고
    • Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity
    • Bates EA, Victor M, Jones AK, Shi Y, Hart AC: Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity. J Neurosci 2006; 26: 2830-2838.
    • (2006) J Neurosci , vol.26 , pp. 2830-2838
    • Bates, E.A.1    Victor, M.2    Jones, A.K.3    Shi, Y.4    Hart, A.C.5
  • 22
    • 35448970692 scopus 로고    scopus 로고
    • Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: In vivo interaction with early-onset Alzheimer disease genes
    • Li A, Xie Z, Dong Y, McKay KM, McKee ML, Tanzi RE: Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum Mol Genet 2007; 16: 2626-2639.
    • (2007) Hum Mol Genet , vol.16 , pp. 2626-2639
    • Li, A.1    Xie, Z.2    Dong, Y.3    McKay, K.M.4    McKee, M.L.5    Tanzi, R.E.6
  • 25
    • 52949083619 scopus 로고    scopus 로고
    • A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in-synuclein transgenic C. elegans
    • Kuwahara T, Koyama A, Koyama S, Yoshina S, Ren CH, Kato T, Mitani S, Iwatsubo T: A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in-synuclein transgenic C. elegans . Hum Mol Genet 2008; 17: 2997-3009.
    • (2008) Hum Mol Genet , vol.17 , pp. 2997-3009
    • Kuwahara, T.1    Koyama, A.2    Koyama, S.3    Yoshina, S.4    Ren, C.H.5    Kato, T.6    Mitani, S.7    Iwatsubo, T.8
  • 26
    • 33751404334 scopus 로고    scopus 로고
    • Whole genome RNAi screens for increased longevity: Important new insights but not the whole story
    • Lee SS: Whole genome RNAi screens for increased longevity: important new insights but not the whole story. Exp Gerontol 2006; 41: 968-973.
    • (2006) Exp Gerontol , vol.41 , pp. 968-973
    • Lee, S.S.1
  • 27
    • 38349109305 scopus 로고    scopus 로고
    • The genetics of ageing: Insight from genome-wide approaches in invertebrate model organisms
    • Kennedy BK: The genetics of ageing: insight from genome-wide approaches in invertebrate model organisms. J Intern Med 2008; 263: 142-152.
    • (2008) J Intern Med , vol.263 , pp. 142-152
    • Kennedy, B.K.1
  • 29
    • 36248964713 scopus 로고    scopus 로고
    • Gene activities that mediate increased life span of C. elegans insulin-like signalling mutants
    • Samuelson AV, Carr CE, Ruvkun G: Gene activities that mediate increased life span of C. elegans insulin-like signalling mutants. Genes Dev 2007; 21: 2976-2994.
    • (2007) Genes Dev , vol.21 , pp. 2976-2994
    • Samuelson, A.V.1    Carr, C.E.2    Ruvkun, G.3
  • 30
    • 34447636066 scopus 로고    scopus 로고
    • Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan
    • Kim Y, Sun H: Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan. Aging Cell 2007; 6: 489-503.
    • (2007) Aging Cell , vol.6 , pp. 489-503
    • Kim, Y.1    Sun, H.2
  • 32
    • 34247569105 scopus 로고    scopus 로고
    • Lifespan regulation by evolutionarily conserved genes essential for viability
    • Curran SP, Ruvkun G: Lifespan regulation by evolutionarily conserved genes essential for viability. PloS Genet 2007; 3: 479-487.
    • (2007) PloS Genet , vol.3 , pp. 479-487
    • Curran, S.P.1    Ruvkun, G.2
  • 33
    • 34447646492 scopus 로고    scopus 로고
    • Longevity determined by developmental arrest genes in Caenorhabditis elegans
    • Chen D, Pan KZ, Palter JE, Kapahi P: Longevity determined by developmental arrest genes in Caenorhabditis elegans . Aging Cell 2007; 6: 525-533.
    • (2007) Aging Cell , vol.6 , pp. 525-533
    • Chen, D.1    Pan, K.Z.2    Palter, J.E.3    Kapahi, P.4
  • 36
    • 34547631266 scopus 로고    scopus 로고
    • Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster
    • Zhan M, Yamaza H, Sun Y, Sinclair J, Li H, Zou S: Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster . Genome Res 2007; 17: 1236-1243.
    • (2007) Genome Res , vol.17 , pp. 1236-1243
    • Zhan, M.1    Yamaza, H.2    Sun, Y.3    Sinclair, J.4    Li, H.5    Zou, S.6
  • 37
    • 0034644270 scopus 로고    scopus 로고
    • The segment polarity network is a robust developmental module
    • Von Dassow G, Meir E, Munro E, Odell G: The segment polarity network is a robust developmental module. Nature 2000; 406: 188-192.
    • (2000) Nature , vol.406 , pp. 188-192
    • Von Dassow, G.1    Meir, E.2    Munro, E.3    Odell, G.4
  • 38
    • 62549093118 scopus 로고    scopus 로고
    • Benchmarks for identification of ordinary differential equations from time series data
    • Gennemark P, Wedelin D: Benchmarks for identification of ordinary differential equations from time series data. Bioinformatics 2009; 25: 780-786.
    • (2009) Bioinformatics , vol.25 , pp. 780-786
    • Gennemark, P.1    Wedelin, D.2
  • 40
    • 0037433769 scopus 로고    scopus 로고
    • Statistical tests for identifying differentially expressed genes in time-course microarray experiments
    • Park T, Yi SG, Lee S, Lee SY, Yoo DH, Ahn JI, Lee YS: Statistical tests for identifying differentially expressed genes in time-course microarray experiments. Bioinformatics 2003; 19: 694-703.
    • (2003) Bioinformatics , vol.19 , pp. 694-703
    • Park, T.1    Yi, S.G.2    Lee, S.3    Lee, S.Y.4    Yoo, D.H.5    Ahn, J.I.6    Lee, Y.S.7
  • 41
    • 33750414249 scopus 로고    scopus 로고
    • A multivariate empirical Bayes statistic for replicated microarray time course data
    • Tai YC, Speed TP: A multivariate empirical Bayes statistic for replicated microarray time course data. Annals Stat 2006; 34: 2387-2412.
    • (2006) Annals Stat , vol.34 , pp. 2387-2412
    • Tai, Y.C.1    Speed, T.P.2
  • 42
    • 8844277626 scopus 로고    scopus 로고
    • Analysing time series gene expression data
    • Bar-Joseph Z: Analysing time series gene expression data. Bioinformatics 2004; 20: 2493-2503.
    • (2004) Bioinformatics , vol.20 , pp. 2493-2503
    • Bar-Joseph, Z.1
  • 43
    • 0042838381 scopus 로고    scopus 로고
    • Comparing the continuous representation of time-series expression profiles to identify differentially expressed genes
    • Bar-Joseph Z, Gerber G, Simon I, Gifford DK, Jaakkola TS: Comparing the continuous representation of time-series expression profiles to identify differentially expressed genes. Proc Natl Acad Sci USA 2003; 100: 10146-10151.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10146-10151
    • Bar-Joseph, Z.1    Gerber, G.2    Simon, I.3    Gifford, D.K.4    Jaakkola, T.S.5
  • 45
  • 46
    • 0038388109 scopus 로고    scopus 로고
    • Reproducibility assessment of independent component analysis of expression ratios from DNA microarrays
    • Kreil DP, MacKay DJC: Reproducibility assessment of independent component analysis of expression ratios from DNA microarrays. Comp Funct Genom 2003; 4: 300-317.
    • (2003) Comp Funct Genom , vol.4 , pp. 300-317
    • Kreil, D.P.1    Djc, M.2
  • 48
    • 1542473171 scopus 로고    scopus 로고
    • Application of independent component analysis to microarrays
    • Lee SI, Batzoglou S: Application of independent component analysis to microarrays. Genome Biol 2003; 4:R76.
    • (2003) Genome Biol , vol.4
    • Lee, S.I.1    Batzoglou, S.2
  • 49
    • 0037246661 scopus 로고    scopus 로고
    • Wavelets in bioinformatics and computational biology: State of art and perspectives
    • Liò P: Wavelets in bioinformatics and computational biology: state of art and perspectives. Bioinformatics 2003; 19: 2-9.
    • (2003) Bioinformatics , vol.19 , pp. 2-9
    • Liò, P.1
  • 50
    • 27744459345 scopus 로고    scopus 로고
    • A new algorithm for comparing and visualizing relationships between hierarchical and flat gene expression data clusterings
    • Torrente A, Kapushesky M, Brazma A: A new algorithm for comparing and visualizing relationships between hierarchical and flat gene expression data clusterings. Bioinformatics 2005; 21: 3993-3999.
    • (2005) Bioinformatics , vol.21 , pp. 3993-3999
    • Torrente, A.1    Kapushesky, M.2    Brazma, A.3
  • 51
    • 4444305034 scopus 로고    scopus 로고
    • Mixture models for assessing differential expression in complex tissues using microarray data
    • Ghosh D: Mixture models for assessing differential expression in complex tissues using microarray data. Bioinformatics 2004; 20: 1663-1669.
    • (2004) Bioinformatics , vol.20 , pp. 1663-1669
    • Ghosh, D.1
  • 52
    • 4944252468 scopus 로고    scopus 로고
    • Using hidden Markov models to analyse gene expression time course data
    • Schliep A, Schonhuth A, Steinhoff C: Using hidden Markov models to analyse gene expression time course data. Bioinformatics 2003; 19:i255-i263.
    • (2003) Bioinformatics , vol.19
    • Schliep, A.1    Schonhuth, A.2    Steinhoff, C.3
  • 53
    • 33644639875 scopus 로고    scopus 로고
    • A novel HMMbased clustering algorithm for the analysis of gene expression time-course data
    • Yujing Z, Garcia-Frias J: A novel HMMbased clustering algorithm for the analysis of gene expression time-course data. Comput Stat Data Anal 2006; 50: 2472-2494.
    • (2006) Comput Stat Data Anal , vol.50 , pp. 2472-2494
    • Yujing, Z.1    Garcia-Frias, J.2
  • 54
    • 41349101972 scopus 로고    scopus 로고
    • Statistical inference of transcriptional module-based gene networks from time course gene expression profiles by using state space models
    • Hirose O, Yoshida R, Imoto S, Yamaguchi R, Higuchi T, Charnock-Jones DS, Print C, Miyano S: Statistical inference of transcriptional module-based gene networks from time course gene expression profiles by using state space models. Bioinformatics 2008; 24: 932-942.
    • (2008) Bioinformatics , vol.24 , pp. 932-942
    • Hirose, O.1    Yoshida, R.2    Imoto, S.3    Yamaguchi, R.4    Higuchi, T.5    Charnock-Jones, D.S.6    Print, C.7    Miyano, S.8
  • 55
    • 0842309206 scopus 로고    scopus 로고
    • Inferring gene networks from time series microarray data using dynamic bayesian networks
    • Kim S, Imoto S, Miyano S: Inferring gene networks from time series microarray data using dynamic bayesian networks. Bioinformatics 2003; 4: 228-235.
    • (2003) Bioinformatics , vol.4 , pp. 228-235
    • Kim, S.1    Imoto, S.2    Miyano, S.3
  • 56
    • 13844253637 scopus 로고    scopus 로고
    • A bayesian approach to reconstructing genetic regulatory networks with hidden factors
    • Beal MJ, Falciani F, Ghahramani Z, Rangel C, Wild DL: A bayesian approach to reconstructing genetic regulatory networks with hidden factors. Bioinformatics 2004; 21: 349-356.
    • (2004) Bioinformatics , vol.21 , pp. 349-356
    • Beal, M.J.1    Falciani, F.2    Ghahramani, Z.3    Rangel, C.4    Wild, D.L.5
  • 57
    • 3142671295 scopus 로고    scopus 로고
    • Modeling genetic regulatory networks using gene expression profiling and state-space models
    • Husmeier D, Dybowski R, Roberts S (eds), London, Springer
    • Rangel C, Angus J, Ghahramani Z, Wild D: Modeling genetic regulatory networks using gene expression profiling and state-space models; in Husmeier D, Dybowski R, Roberts S (eds): Probabilistic Modeling in Bioinformatics and Medical Informatics. London, Springer, 2005, pp 269-293.
    • (2005) Probabilistic Modeling in Bioinformatics and Medical Informatics , pp. 269-293
    • Rangel, C.1    Angus, J.2    Ghahramani, Z.3    Wild, D.4
  • 61
    • 33947592830 scopus 로고    scopus 로고
    • Off-target effects associated with long dsRNAs in Drosophila RNAi screens
    • Moffat J, Reiling JH, Sabatini DM: Off-target effects associated with long dsRNAs in Drosophila RNAi screens. Trends Pharmacol Sci 2007; 28: 149-151.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 149-151
    • Moffat, J.1    Reiling, J.H.2    Sabatini, D.M.3
  • 62
    • 23144436831 scopus 로고    scopus 로고
    • DsCheck: Highly sensitive off-target search software for doublestranded RNA-mediated RNA interference
    • Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S: dsCheck: highly sensitive off-target search software for doublestranded RNA-mediated RNA interference. Nucleic Acids Res 2005; 33:W589-W591.
    • (2005) Nucleic Acids Res , vol.33
    • Naito, Y.1    Yamada, T.2    Matsumiya, T.3    Ui-Tei, K.4    Saigo, K.5    Morishita, S.6


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