FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing's sarcoma cells

Biochemical and Biophysical Research Communications

Volumn 402, Issue 1, 2010, Pages 129-134

  Yang, Liu ^a,b   Hu, Hsien Ming ^a,b   Zielinska Kwiatkowska, Anna ^a,b   Chansky, Howard A ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

Author keywords

Ewing's sarcoma; EWS Fli1; FOXO1; Inducible siRNA; Oncogenic fusion protein; RNA interference; Tumor suppressor gene

Indexed keywords

DICKKOPF 1 PROTEIN; DOXYCYCLINE; EWS FLI1 ONCOGENIC FUSION PROTEIN; HYBRID PROTEIN; PROTEIN P57; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DNA DETERMINATION; DNA MICROARRAY; EWING SARCOMA; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; SARCOMA CELL; TUMOR CELL CULTURE;

BONE NEOPLASMS; CELL LINE, TUMOR; DOXYCYCLINE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; ONCOGENE PROTEINS, FUSION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEIN C-FLI-1; RNA, SMALL INTERFERING; SARCOMA, EWING'S; SUPPRESSION, GENETIC;

EID: 78049300953     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.129     Document Type: Article

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