Future challenges in the use of magnetic resonance imaging for the diagnosis of iron overload

Blood Transfusion

Volumn 8, Issue 4, 2010, Pages 309-310

  Kolnagou, Annita ^a   Kontoghiorghes, George J ^a  

^a Postgraduate Research Institute Science Technology Environment and Medicine   (Cyprus)

Author keywords

[No Author keywords available]

Indexed keywords

DEFERIPRONE; DEFEROXAMINE; FERRITIN; IRON;

ARTHROPATHY; CARDIOMYOPATHY; CARDIOVASCULAR RISK; CHELATION THERAPY; CONGESTIVE HEART FAILURE; DIAGNOSTIC PROCEDURE; FERRITIN BLOOD LEVEL; HEALTH CARE COST; IRON OVERLOAD; LETTER; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN DISTRIBUTION; THALASSEMIA;

HEART; HUMANS; IRON OVERLOAD; MAGNETIC RESONANCE IMAGING; THALASSEMIA;

EID: 78049298690     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2010.0017-10     Document Type: Letter

References (5)

1. Mavrogeni S. Evaluation of myocardial iron overload using magnetic resonance imaging. Blood Transfus 2009; 7: 183-7.
2. Kolnagou A, Eracleous E, Economides Ch, Kontoghiorghes GJ. Low serum ferritin levels are misleading for detecting excess cardiac iron loading and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2*. Hemoglobin 2006; 30: 219-27.
3. Kolnagou A, Yazman D, Economides C, et al. Uses and limitations of serum ferritin, magnetic resonance imaging T2 and T2* in the diagnosis of iron overload and in the ferrikinetics of normalization of the iron stores in thalassemia using the International Committee on Chelation deferiprone/ deferoxamine combination protocol. Hemoglobin 2009; 33: 312-22.
4. Kolnagou A, Michaelides Y, Kontos C, et al. Myocyte damage and loss of myofibers is the potential mechanism of iron overload toxicity in congestive cardiac failure in thalassemia. Complete reversal of the cardiomyopathy and normalization of iron load by deferiprone. Hemoglobin 2008; 32: 17-28.
5. Ramazzotti A, Pepe A, Positano V, et al. Multicenter validation of the magnetic resonance T2* technique for segmental and global quantification of myocardial iron. J Magn Reson Imaging 2009; 30: 62-8.