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Volumn 18, Issue 11, 2010, Pages 2093-2100

Altered intramuscular lipid metabolism relates to diminished insulin action in men, but not women, in progression to diabetes

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; TRIACYLGLYCEROL;

EID: 78049296939     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2010.76     Document Type: Article
Times cited : (39)

References (40)
  • 1
    • 33845536057 scopus 로고    scopus 로고
    • Effects of sex and hormone replacement therapy use on the prevalence of isolated impaired fasting glucose and isolated impaired glucose tolerance in subjects with a family history of type 2 diabetes
    • American Diabetes Association GENNID Study Group
    • Van Genugten RE, Utzschneider KM, Tong J et al.; American Diabetes Association GENNID Study Group. Effects of sex and hormone replacement therapy use on the prevalence of isolated impaired fasting glucose and isolated impaired glucose tolerance in subjects with a family history of type 2 diabetes. Diabetes 2006;55:3529-3535.
    • (2006) Diabetes , vol.55 , pp. 3529-3535
    • Van Genugten, R.E.1    Utzschneider, K.M.2    Tong, J.3
  • 2
    • 1542603262 scopus 로고    scopus 로고
    • Gender differences in the prevalence of impaired fasting glycaemia and impaired glucose tolerance in Mauritius. Does sex matter?
    • Williams JW, Zimmet PZ, Shaw JE et al. Gender differences in the prevalence of impaired fasting glycaemia and impaired glucose tolerance in Mauritius. Does sex matter? Diabet Med 2003;20:915-920.
    • (2003) Diabet Med , vol.20 , pp. 915-920
    • Williams, J.W.1    Zimmet, P.Z.2    Shaw, J.E.3
  • 3
    • 49649084226 scopus 로고    scopus 로고
    • Sex differences in diabetes risk and the effect of intensive lifestyle modification in the Diabetes Prevention Program
    • Diabetes Prevention Program
    • Perreault L, Ma Y, Dagogo-Jack S et al.; Diabetes Prevention Program. Sex differences in diabetes risk and the effect of intensive lifestyle modification in the Diabetes Prevention Program. Diabetes Care 2008;31:1416-1421.
    • (2008) Diabetes Care , vol.31 , pp. 1416-1421
    • Perreault, L.1    Ma, Y.2    Dagogo-Jack, S.3
  • 4
    • 0028838077 scopus 로고
    • Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using positron emission tomography
    • Nuutila P, Knuuti MJ, Mäki M et al. Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using positron emission tomography. Diabetes 1995;44:31-36.
    • (1995) Diabetes , vol.44 , pp. 31-36
    • Nuutila, P.1    Knuuti, M.J.2    Mäki, M.3
  • 5
    • 0021723041 scopus 로고
    • Sex and insulin sensitivity
    • Yki-Järvinen H. Sex and insulin sensitivity. Metab Clin Exp 1984;33: 1011-1015.
    • (1984) Metab Clin Exp , vol.33 , pp. 1011-1015
    • Yki-Järvinen, H.1
  • 6
    • 0034630441 scopus 로고    scopus 로고
    • Overweight, obesity, and health risk National Task Force on the Prevention and Treatment of Obesity
    • Overweight, obesity, and health risk. National Task Force on the Prevention and Treatment of Obesity. Arch Intern Med 2000;160:898-904.
    • (2000) Arch Intern Med , vol.160 , pp. 898-904
  • 7
    • 0030027918 scopus 로고    scopus 로고
    • Insulin resistance and body fat distribution
    • Yamashita S, Nakamura T, Shimomura I et al. Insulin resistance and body fat distribution. Diabetes Care 1996;19:287-291.
    • (1996) Diabetes Care , vol.19 , pp. 287-291
    • Yamashita, S.1    Nakamura, T.2    Shimomura, I.3
  • 9
    • 0034112806 scopus 로고    scopus 로고
    • Intramuscular lipid content is increased in obesity and decreased by weight loss
    • Goodpaster BH, Theriault R, Watkins SC, Kelley DE. Intramuscular lipid content is increased in obesity and decreased by weight loss. Metab Clin Exp 2000;49:467-472.
    • (2000) Metab Clin Exp , vol.49 , pp. 467-472
    • Goodpaster, B.H.1    Theriault, R.2    Watkins, S.C.3    Kelley, D.E.4
  • 10
    • 0032934826 scopus 로고    scopus 로고
    • Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: A 1H NMR spectroscopy study
    • Krssak M, Falk Petersen K, Dresner A et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 1999;42:113-116.
    • (1999) Diabetologia , vol.42 , pp. 113-116
    • Krssak, M.1    Falk Petersen, K.2    Dresner, A.3
  • 11
    • 0030969532 scopus 로고    scopus 로고
    • Skeletal muscle triglyceride levels are inversely related to insulin action
    • Pan DA, Lillioja S, Kriketos AD et al. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 1997;46:983-988.
    • (1997) Diabetes , vol.46 , pp. 983-988
    • Pan, D.A.1    Lillioja, S.2    Kriketos, A.D.3
  • 12
    • 0032764784 scopus 로고    scopus 로고
    • Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
    • Perseghin G, Scifo P, De Cobelli F et al. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 1999;48:1600-1606.
    • (1999) Diabetes , vol.48 , pp. 1600-1606
    • Perseghin, G.1    Scifo, P.2    De Cobelli, F.3
  • 13
    • 0036300538 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
    • Itani SI, Ruderman NB, Schmieder F, Boden G. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 2002;51:2005-2011.
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Schmieder, F.3    Boden, G.4
  • 14
    • 0033749620 scopus 로고    scopus 로고
    • Signalling aspects of insulin resistance in skeletal muscle: Mechanisms induced by lipid oversupply
    • Schmitz-Peiffer C. Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply. Cell Signal 2000;12:583-594.
    • (2000) Cell Signal , vol.12 , pp. 583-594
    • Schmitz-Peiffer, C.1
  • 16
    • 0033952722 scopus 로고    scopus 로고
    • Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides
    • Manco M, Mingrone G, Greco AV et al. Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides. Metab Clin Exp 2000;49:220-224.
    • (2000) Metab Clin Exp , vol.49 , pp. 220-224
    • Manco, M.1    Mingrone, G.2    Greco, A.V.3
  • 17
    • 0036087221 scopus 로고    scopus 로고
    • Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects
    • Roepstorff C, Steffensen CH, Madsen M et al. Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects. Am J Physiol Endocrinol Metab 2002;282:E435-E447.
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Roepstorff, C.1    Steffensen, C.H.2    Madsen, M.3
  • 18
    • 0346732371 scopus 로고    scopus 로고
    • Intramyocellular lipid changes in men and women during aerobic exercise: A (1)H-magnetic resonance spectroscopy study
    • White LJ, Ferguson MA, McCoy SC, Kim H. Intramyocellular lipid changes in men and women during aerobic exercise: a (1)H-magnetic resonance spectroscopy study. J Clin Endocrinol Metab 2003;88:5638-5643.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5638-5643
    • White, L.J.1    Ferguson, M.A.2    McCoy, S.C.3    Kim, H.4
  • 19
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183-1197.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 20
    • 0027481387 scopus 로고
    • Evaluation of dual energy X-ray absorptiometry as a method of measurement of body fat
    • Pritchard JE, Nowson CA, Strauss BJ et al. Evaluation of dual energy X-ray absorptiometry as a method of measurement of body fat. Eur J Clin Nutr 1993;47:216-228.
    • (1993) Eur J Clin Nutr , vol.47 , pp. 216-228
    • Pritchard, J.E.1    Nowson, C.A.2    Strauss, B.J.3
  • 21
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and resistance
    • DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214-E223.
    • (1979) Am J Physiol , vol.237
    • Defronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 22
    • 0016723939 scopus 로고
    • Percutaneous needle biopsy of skeletal muscle in physiological and clinical research
    • Bergstrom J. Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand J Clin Lab Invest 1975;35:609-616.
    • (1975) Scand J Clin Lab Invest , vol.35 , pp. 609-616
    • Bergstrom, J.1
  • 23
    • 8944256349 scopus 로고
    • New methods for calculating metabolic rate with special reference to protein metabolism
    • WEIR JB. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol (Lond) 1949;109:1-9.
    • (1949) J Physiol (Lond) , vol.109 , pp. 1-9
    • Weir, J.B.1
  • 24
    • 4344687311 scopus 로고    scopus 로고
    • Gender differences in insulin action after a single bout of exercise
    • Perreault L, Lavely JM, Bergman BC, Horton TJ. Gender differences in insulin action after a single bout of exercise. J Appl Physiol 2004;97: 1013-1021.
    • (2004) J Appl Physiol , vol.97 , pp. 1013-1021
    • Perreault, L.1    Lavely, J.M.2    Bergman, B.C.3    Horton, T.J.4
  • 25
    • 70349648330 scopus 로고    scopus 로고
    • Intramuscular lipid metabolism in the insulin resistance of smoking
    • Bergman BC, Perreault L, Hunerdosse DM et al. Intramuscular lipid metabolism in the insulin resistance of smoking. Diabetes 2009;58: 2220-2227.
    • (2009) Diabetes , vol.58 , pp. 2220-2227
    • Bergman, B.C.1    Perreault, L.2    Hunerdosse, D.M.3
  • 26
    • 0026476541 scopus 로고
    • A fast and versatile method for extraction and quantitation of long-chain acyl-CoA esters from tissue: Content of individual long-chain acyl-CoA esters in various tissues from fed rat
    • Rosendal J, Knudsen J. A fast and versatile method for extraction and quantitation of long-chain acyl-CoA esters from tissue: content of individual long-chain acyl-CoA esters in various tissues from fed rat. Anal Biochem 1992;207:63-67.
    • (1992) Anal Biochem , vol.207 , pp. 63-67
    • Rosendal, J.1    Knudsen, J.2
  • 27
    • 0032693382 scopus 로고    scopus 로고
    • Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment
    • Patterson BW, Zhao G, Elias N, Hachey DL, Klein S. Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment. J Lipid Res 1999;40:2118-2124.
    • (1999) J Lipid Res , vol.40 , pp. 2118-2124
    • Patterson, B.W.1    Zhao, G.2    Elias, N.3    Hachey, D.L.4    Klein, S.5
  • 28
    • 0031801379 scopus 로고    scopus 로고
    • Improved accuracy and precision of gas chromatography/mass spectrometry measurements for metabolic tracers
    • Patterson BW, Zhao G, Klein S. Improved accuracy and precision of gas chromatography/mass spectrometry measurements for metabolic tracers. Metab Clin Exp 1998;47:706-712.
    • (1998) Metab Clin Exp , vol.47 , pp. 706-712
    • Patterson, B.W.1    Zhao, G.2    Klein, S.3
  • 30
    • 0023245416 scopus 로고
    • Estimation of endogenous glucose production during hyperinsulinemic- euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates
    • Finegood DT, Bergman RN, Vranic M. Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 1987;36:914-924.
    • (1987) Diabetes , vol.36 , pp. 914-924
    • Finegood, D.T.1    Bergman, R.N.2    Vranic, M.3
  • 31
    • 0033645223 scopus 로고    scopus 로고
    • Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise
    • Blaak EE, Van Aggel-Leijssen DP, Wagenmakers AJ, Saris WH, Van Baak MA. Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise. Diabetes 2000;49:2102-2107.
    • (2000) Diabetes , vol.49 , pp. 2102-2107
    • Blaak, E.E.1    Van Aggel-Leijssen, D.P.2    Wagenmakers, A.J.3    Saris, W.H.4    Van Baak, M.A.5
  • 32
    • 78049262729 scopus 로고    scopus 로고
    • Inflexibility in intramuscular triglyceride fractional synthesis distinguishes prediabetes from obesity in humans
    • e-pub ahead of print 24 December 2009
    • Perreault L, Bergman BC, Hunerdosse DM, Playdon MC, Eckel RH. Inflexibility in intramuscular triglyceride fractional synthesis distinguishes prediabetes from obesity in humans. Obesity (Silver Spring) 2009; e-pub ahead of print 24 December 2009.
    • (2009) Obesity (Silver Spring)
    • Perreault, L.1    Bergman, B.C.2    Hunerdosse, D.M.3    Playdon, M.C.4    Eckel, R.H.5
  • 33
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
    • Goodpaster BH, He J, Watkins S, Kelley DE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab 2001;86:5755-5761.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5755-5761
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3    Kelley, D.E.4
  • 34
    • 34249894505 scopus 로고    scopus 로고
    • Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
    • Liu L, Zhang Y, Chen N et al. Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance. J Clin Invest 2007;117:1679-1689.
    • (2007) J Clin Invest , vol.117 , pp. 1679-1689
    • Liu, L.1    Zhang, Y.2    Chen, N.3
  • 35
    • 38949161524 scopus 로고    scopus 로고
    • Determinants of intramyocellular triglyceride turnover: Implications for insulin sensitivity
    • Moro C, Bajpeyi S, Smith SR. Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity. Am J Physiol Endocrinol Metab 2008;294:E203-E213.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Moro, C.1    Bajpeyi, S.2    Smith, S.R.3
  • 36
    • 34249915334 scopus 로고    scopus 로고
    • Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
    • Schenk S, Horowitz J F. Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. J Clin Invest 2007;117:1690-1698.
    • (2007) J Clin Invest , vol.117 , pp. 1690-1698
    • Schenk, S.1    Horowitz, J.F.2
  • 37
    • 42449094965 scopus 로고    scopus 로고
    • Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
    • Toledo FG, Menshikova EV, Azuma K et al. Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 2008;57:987-994.
    • (2008) Diabetes , vol.57 , pp. 987-994
    • Toledo, F.G.1    Menshikova, E.V.2    Azuma, K.3
  • 38
    • 42949084209 scopus 로고    scopus 로고
    • Muscular diacylglycerol metabolism and insulin resistance
    • Timmers S, Schrauwen P, de Vogel J. Muscular diacylglycerol metabolism and insulin resistance. Physiol Behav 2008;94:242-251.
    • (2008) Physiol Behav , vol.94 , pp. 242-251
    • Timmers, S.1    Schrauwen, P.2    De Vogel, J.3
  • 39
    • 1842405349 scopus 로고    scopus 로고
    • Leptin directly alters lipid partitioning in skeletal muscle
    • Muoio DM, Dohm GL, Fiedorek FT Jr et al. Leptin directly alters lipid partitioning in skeletal muscle. Diabetes 1997;46:1360-1363.
    • (1997) Diabetes , vol.46 , pp. 1360-1363
    • Muoio, D.M.1    Dohm, G.L.2    Fiedorek Jr., F.T.3
  • 40
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002;8:1288-1295.
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3


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