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Volumn 54, Issue 11, 2010, Pages 4843-4850

Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: Inhibition of stage conversion of the parasite cyst form and study of new derivative compounds

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; FR 235222; HISTONE DEACETYLASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 78049278807     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00462-10     Document Type: Article
Times cited : (54)

References (36)
  • 1
    • 0026567941 scopus 로고
    • In vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against the cyst form of Toxoplasma gondii
    • Araujo, F. G., J. Huskinson-Mark, W. E. Gutteridge, and J. S. Remington. 1992. In vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against the cyst form of Toxoplasma gondii. Antimicrob. Agents Chemother. 36:326-330.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 326-330
    • Araujo, F.G.1    Huskinson-Mark, J.2    Gutteridge, W.E.3    Remington, J.S.4
  • 2
    • 0026073466 scopus 로고
    • Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii
    • Araujo, F. G., J. Huskinson, and J. S. Remington. 1991. Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii. Antimicrob. Agents Chemother. 35:293-299.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 293-299
    • Araujo, F.G.1    Huskinson, J.2    Remington, J.S.3
  • 3
    • 33745154817 scopus 로고    scopus 로고
    • Reactivation of Toxoplasma retinochoroiditis under atovaquone therapy in an immunocompetent patient
    • Baatz, H., A. Mirshahi, J. Puchta, H. Gumbel, and L. O. Hattenbach. 2006. Reactivation of Toxoplasma retinochoroiditis under atovaquone therapy in an immunocompetent patient. Ocul. Immunol. Inflamm. 14:185-187.
    • (2006) Ocul. Immunol. Inflamm. , vol.14 , pp. 185-187
    • Baatz, H.1    Mirshahi, A.2    Puchta, J.3    Gumbel, H.4    Hattenbach, L.O.5
  • 5
    • 67349214385 scopus 로고    scopus 로고
    • Toxoplasma gondii: 25 Years and 25 major advances for the field
    • Boothroyd, J. C. 2009. Toxoplasma gondii: 25 years and 25 major advances for the field. Int. J. Parasitol. 39:935-946.
    • (2009) Int. J. Parasitol. , vol.39 , pp. 935-946
    • Boothroyd, J.C.1
  • 7
    • 51149121669 scopus 로고    scopus 로고
    • Toxoplasma gondii gene expression is under the control of regulatory pathways acting through chromatin structure
    • Bougdour, A., C. F. Sautel, D. Cannella, L. Braun, and M. A. Hakimi. 2008. Toxoplasma gondii gene expression is under the control of regulatory pathways acting through chromatin structure. Parasite 15:206-210.
    • (2008) Parasite , vol.15 , pp. 206-210
    • Bougdour, A.1    Sautel, C.F.2    Cannella, D.3    Braun, L.4    Hakimi, M.A.5
  • 9
    • 34347267271 scopus 로고    scopus 로고
    • Adapting a conventional PCR assay for Toxoplasma gondii detection to real-time quantitative PCR including a competitive internal control
    • Brenier-Pinchart, M. P., V. Morand-Bui, H. Fricker-Hidalgo, V. Equy, R. Marlu, and H. Pelloux. 2007. Adapting a conventional PCR assay for Toxoplasma gondii detection to real-time quantitative PCR including a competitive internal control. Parasite 14:149-154.
    • (2007) Parasite , vol.14 , pp. 149-154
    • Brenier-Pinchart, M.P.1    Morand-Bui, V.2    Fricker-Hidalgo, H.3    Equy, V.4    Marlu, R.5    Pelloux, H.6
  • 10
    • 0036569754 scopus 로고    scopus 로고
    • Randomized phase II trial of atovaquone with pyrimethamine or sulfadiazine for treatment of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome: ACTG 237/ANRS 039 Study
    • AIDS Clinical Trials Group 237/Agence Nationale de Recherche sur le SIDA, Essai 039
    • Chirgwin, K., R. Hafner, C. Leport, J. Remington, J. Andersen, E. M. Bosler, C. Roque, N. Rajicic, V. McAuliffe, P. Morlat, D. T. Jayaweera, J. L. Vilde, and B. J. Luft. 2002. Randomized phase II trial of atovaquone with pyrimethamine or sulfadiazine for treatment of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome: ACTG 237/ANRS 039 Study. AIDS Clinical Trials Group 237/Agence Nationale de Recherche sur le SIDA, Essai 039. Clin. Infect. Dis. 34:1243-1250.
    • (2002) Clin. Infect. Dis. , vol.34 , pp. 1243-1250
    • Chirgwin, K.1    Hafner, R.2    Leport, C.3    Remington, J.4    Andersen, J.5    Bosler, E.M.6    Roque, C.7    Rajicic, N.8    McAuliffe, V.9    Morlat, P.10    Jayaweera, D.T.11    Vilde, J.L.12    Luft, B.J.13
  • 11
    • 0019831719 scopus 로고
    • Separation of Isospora (Toxoplasma) gondii cysts and cystozoites from mouse brain tissue by continuous density-gradient centrifugation
    • Cornelissen, A. W., J. P. Overdulve, and J. M. Hoenderboom. 1981. Separation of Isospora (Toxoplasma) gondii cysts and cystozoites from mouse brain tissue by continuous density-gradient centrifugation. Parasitology 83:103-108.
    • (1981) Parasitology , vol.83 , pp. 103-108
    • Cornelissen, A.W.1    Overdulve, J.P.2    Hoenderboom, J.M.3
  • 14
    • 0030497769 scopus 로고    scopus 로고
    • Treatment regimens for patients with toxoplasmic encephalitis
    • Fung, H. B., and H. L. Kirschenbaum. 1996. Treatment regimens for patients with toxoplasmic encephalitis. Clin. Ther. 18:1037-1056.
    • (1996) Clin. Ther. , vol.18 , pp. 1037-1056
    • Fung, H.B.1    Kirschenbaum, H.L.2
  • 16
    • 0029161774 scopus 로고
    • Monoclonal rat antibodies directed against Toxoplasma gondii suitable for studying tachyzoite-bradyzoite interconversion in vivo
    • Gross, U., H. Bormuth, C. Gaissmaier, C. Dittrich, V. Krenn, W. Bohne, and D. J. Ferguson. 1995. Monoclonal rat antibodies directed against Toxoplasma gondii suitable for studying tachyzoite-bradyzoite interconversion in vivo. Clin. Diagn. Lab. Immunol. 2:542-548.
    • (1995) Clin. Diagn. Lab. Immunol. , vol.2 , pp. 542-548
    • Gross, U.1    Bormuth, H.2    Gaissmaier, C.3    Dittrich, C.4    Krenn, V.5    Bohne, W.6    Ferguson, D.J.7
  • 17
    • 34548658056 scopus 로고    scopus 로고
    • Epigenetics in Apicomplexa: Control of gene expression during cell cycle progression, differentiation and antigenic variation
    • Hakimi, M. A., and K. W. Deitsch. 2007. Epigenetics in Apicomplexa: control of gene expression during cell cycle progression, differentiation and antigenic variation. Curr. Opin. Microbiol. 10:357-362.
    • (2007) Curr. Opin. Microbiol. , vol.10 , pp. 357-362
    • Hakimi, M.A.1    Deitsch, K.W.2
  • 18
    • 26044470703 scopus 로고    scopus 로고
    • Biology and epidemiology of Toxoplasma gondii in man and animals
    • Hill, D. E., S. Chirukandoth, and J. P. Dubey. 2005. Biology and epidemiology of Toxoplasma gondii in man and animals. Anim. Health Res. Rev. 6:41-61.
    • (2005) Anim. Health Res. Rev. , vol.6 , pp. 41-61
    • Hill, D.E.1    Chirukandoth, S.2    Dubey, J.P.3
  • 19
    • 0025955333 scopus 로고
    • Evaluation of the effect of drugs on the cyst form of Toxoplasma gondii
    • Huskinson-Mark, J., F. G. Araujo, and J. S. Remington. 1991. Evaluation of the effect of drugs on the cyst form of Toxoplasma gondii. J. Infect. Dis. 164:170-171.
    • (1991) J. Infect. Dis. , vol.164 , pp. 170-171
    • Huskinson-Mark, J.1    Araujo, F.G.2    Remington, J.S.3
  • 20
    • 37049002223 scopus 로고    scopus 로고
    • Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes
    • Iyer, L. M., V. Anantharaman, M. Y. Wolf, and L. Aravind. 2008. Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes. Int. J. Parasitol. 38:1-31.
    • (2008) Int. J. Parasitol. , vol.38 , pp. 1-31
    • Iyer, L.M.1    Anantharaman, V.2    Wolf, M.Y.3    Aravind, L.4
  • 21
    • 20444416410 scopus 로고    scopus 로고
    • Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence
    • Kim, S. K., and J. C. Boothroyd. 2005. Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence. J. Immunol. 174:8038-8048.
    • (2005) J. Immunol. , vol.174 , pp. 8038-8048
    • Kim, S.K.1    Boothroyd, J.C.2
  • 22
    • 0036569163 scopus 로고    scopus 로고
    • Toxoplasma gondii tachyzoite-bradyzoite interconversion
    • Lyons, R. E., R. McLeod, and C. W. Roberts. 2002. Toxoplasma gondii tachyzoite-bradyzoite interconversion. Trends Parasitol. 18:198-201.
    • (2002) Trends Parasitol. , vol.18 , pp. 198-201
    • Lyons, R.E.1    McLeod, R.2    Roberts, C.W.3
  • 23
    • 54849442066 scopus 로고    scopus 로고
    • Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation
    • Megged, O., I. Shalit, I. Yaniv, J. Stein, S. Fisher, and I. Levy. 2008. Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation. Pediatr. Transplant. 12:902-905.
    • (2008) Pediatr. Transplant. , vol.12 , pp. 902-905
    • Megged, O.1    Shalit, I.2    Yaniv, I.3    Stein, J.4    Fisher, S.5    Levy, I.6
  • 25
    • 2942541583 scopus 로고    scopus 로고
    • Toxoplasmosis
    • Montoya, J. G., and O. Liesenfeld. 2004. Toxoplasmosis. Lancet 363:1965-1976.
    • (2004) Lancet , vol.363 , pp. 1965-1976
    • Montoya, J.G.1    Liesenfeld, O.2
  • 26
    • 0037300444 scopus 로고    scopus 로고
    • FR235222, a fungal metabolite, is a novel immunosuppressant that inhibits mammalian histone deacetylase (HDAC). I. Taxonomy, fermentation, isolation and biological activities
    • Tokyo
    • Mori, H., Y. Urano, F. Abe, S. Furukawa, S. Furukawa, Y. Tsurumi, K. Sakamoto, M. Hashimoto, S. Takase, M. Hino, and T. Fujii. 2003. FR235222, a fungal metabolite, is a novel immunosuppressant that inhibits mammalian histone deacetylase (HDAC). I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. (Tokyo) 56:72-79.
    • (2003) J. Antibiot. , vol.56 , pp. 72-79
    • Mori, H.1    Urano, Y.2    Abe, F.3    Furukawa, S.4    Furukawa, S.5    Tsurumi, Y.6    Sakamoto, K.7    Hashimoto, M.8    Takase, S.9    Hino, M.10    Fujii, T.11
  • 27
    • 33750531864 scopus 로고    scopus 로고
    • Innovative lead discovery strategies for tropical diseases
    • Nwaka, S., and A. Hudson. 2006. Innovative lead discovery strategies for tropical diseases. Nat. Rev. Drug Discov. 5:941-955.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 941-955
    • Nwaka, S.1    Hudson, A.2
  • 28
    • 23244443547 scopus 로고    scopus 로고
    • Drug resistance hampers our capacity to roll back malaria
    • Olliaro, P. 2005. Drug resistance hampers our capacity to roll back malaria. Clin. Infect. Dis. 41(Suppl. 4):S247-S257.
    • (2005) Clin. Infect. Dis. , vol.41 , Issue.SUPPL. 4
    • Olliaro, P.1
  • 30
    • 0017753376 scopus 로고
    • Specific labeling of intracellular Toxoplasma gondii with uracil
    • Pfefferkorn, E. R., and L. C. Pfefferkorn. 1977. Specific labeling of intracellular Toxoplasma gondii with uracil. J. Protozool. 24:449-453.
    • (1977) J. Protozool. , vol.24 , pp. 449-453
    • Pfefferkorn, E.R.1    Pfefferkorn, L.C.2
  • 31
    • 33750482579 scopus 로고    scopus 로고
    • Conformational flexibility, internal hydrogen bonding, and passive membrane permeability: Successful in silico prediction of the relative permeabilities of cyclic peptides
    • Rezai, T., J. E. Bock, M. V. Zhou, C. Kalyanaraman, R. S. Lokey, and M. P. Jacobson. 2006. Conformational flexibility, internal hydrogen bonding, and passive membrane permeability: successful in silico prediction of the relative permeabilities of cyclic peptides. J. Am. Chem. Soc. 128:14073-14080.
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 14073-14080
    • Rezai, T.1    Bock, J.E.2    Zhou, M.V.3    Kalyanaraman, C.4    Lokey, R.S.5    Jacobson, M.P.6
  • 33
    • 34547890019 scopus 로고    scopus 로고
    • Functions of site-specific histone acetylation and deacetylation
    • Shahbazian, M. D., and M. Grunstein. 2007. Functions of site-specific histone acetylation and deacetylation. Annu. Rev. Biochem. 76:75-100.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 75-100
    • Shahbazian, M.D.1    Grunstein, M.2
  • 34
    • 33745411638 scopus 로고    scopus 로고
    • Histone mediated gene activation in Toxoplasma gondii
    • Sullivan, W. J., Jr., and M. A. Hakimi. 2006. Histone mediated gene activation in Toxoplasma gondii. Mol. Biochem. Parasitol. 148:109-116.
    • (2006) Mol. Biochem. Parasitol. , vol.148 , pp. 109-116
    • Sullivan Jr., W.J.1    Hakimi, M.A.2
  • 35
    • 41849147939 scopus 로고    scopus 로고
    • Migration of Apicomplexa across biological barriers: The Toxoplasma and Plasmodium rides
    • DOI 10.1111/j.1600-0854.2008.00703.x
    • Tardieux, I., and R. Menard. 2008. Migration of Apicomplexa across biological barriers: the Toxoplasma and Plasmodium rides. Traffic 9:627-635. (Pubitemid 351494295)
    • (2008) Traffic , vol.9 , Issue.5 , pp. 627-635
    • Tardieux, I.1    Menard, R.2
  • 36
    • 34249937106 scopus 로고    scopus 로고
    • The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9
    • Van, T. T., S.-K. Kim, M. Camps, J. C. Boothroyd, and L. J. Knoll. 2007. The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9. Int. J. Parasitol. 37:877.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 877
    • Van, T.T.1    Kim, S.-K.2    Camps, M.3    Boothroyd, J.C.4    Knoll, L.J.5


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