Time for test and treat in prevention of mother-to-child transmission programs in low- and middle-income countries

Journal of Acquired Immune Deficiency Syndromes

Volumn 55, Issue 3, 2010, Pages 287-289

  Zolfo, Maria ^a   De Weggheleire, Anja ^a   Schouten, Erik ^b,c   Lynen, Lutgarde ^a  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^b MINISTRY OF HEALTH   (Malawi)

^c Management Sciences for Health ^*  (Malawi)

Author keywords

antiretroviral therapy; breastfeeding; CD4 count; HIV; low and middle income countries; PMTCT

Indexed keywords

NEVIRAPINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

BREAST FEEDING; CD4 LYMPHOCYTE COUNT; DELIVERY; DISEASE TRANSMISSION; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; LOWEST INCOME GROUP; NOTE; PRACTICE GUIDELINE; PREGNANCY; PRIORITY JOURNAL; WORLD HEALTH ORGANIZATION; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV INFECTIONS; NEWBORN; PREGNANCY COMPLICATIONS, INFECTIOUS; PREVENTION AND CONTROL; PUERPERIUM; VERTICAL TRANSMISSION;

ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; FEMALE; HIV INFECTIONS; HUMANS; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; POSTPARTUM PERIOD; PRACTICE GUIDELINES AS TOPIC; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; WORLD HEALTH ORGANIZATION;

EID: 78049252230     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3181eef3da     Document Type: Note

References (25)

1. Townsend CL, Cortina-Borja M, Peckham CS, et al. Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006. AIDS. 2008;22:973-981.
2. WHO UNAIDS, Unicef. Towards universal access. Scaling up priority HIV/AIDS interventions in the health sector. Progress report 2009. Available at: http://data.unaids.org/pub/Report/2009/20090930-tuapr- 2009-en.pdf. Accessed May 24, 2010.
3. WHO. Rapid advice: antiretroviral therapy for HIV infection in adults and adolescents. 2009; Available at: URL: http://www.who.int/hiv/pub/arv/ rapid-advice-art.pdf. Accessed May 18, 2010.
4. WHO. Rapid advice: use of antiretroviral drugs for treating pregnant women and preventing HIV infection in infants. 2009; Available at: URL: http://www.who.int/hiv/pub/mtct/advice/en/. Accessed May 27, 2010.
5. Mofenson LM. Prevention in neglected subpopulations: prevention of mother-to-child transmission of HIV infection. Clin Infect Dis. 2010; 50(Suppl 3):S130-S148.
6. Kuhn L, Aldrovandi G, Sinkala M, et al. Potential impact of new WHO criteria for antiretroviral treatment for prevention of mother-to-child HIV transmission. AIDS. 2010;24:1374-1375.
7. Carter RJ, Dugan K, El-Sadr W, et al. CD4+cell count testing more effective than HIV disease clinical staging in identifying pregnant and post partum women eligible for antiretroviral therapy in resource limited settings. J Acquir Immune Defic Syndr. 2010;X(X):X.
8. WHO. PMTCT strategic vision 2010-2015. 2010; Available at: http://www.who.int/hiv/pub/mtct/strategic-vision/en/. Accessed May 27, 2010.
9. Lowrance DW, Makombe S, Harries AD, et al. A public health approach to rapid scale-up of antiretroviral treatment in Malawi during 2004-2006. J Acquir Immune Defic Syndr. 2008;49:287-293.
10. Becquet R, Ekouevi DK, Arrive E, et al. Universal antiretroviral therapy for pregnant and breast-feeding HIV-1-infected women: towards the elimination of mother-to-child transmission of HIV-1 in resource-limited settings. Clin Infect Dis. 2009;49:1936-1945.
11. Russo G, Lichtner M, Traditi F, et al. Is the time for an AIDS-free new generation different in resource-limited and industrialized countries? AIDS. 2009;23:293-296.
12. WHO. Women and health: today's evidence, tomorrow's agenda. 2009; Available at: http://whqlibdoc.who.int/publications/2009/ 9789241563857-eng.pdf. Accessed May 27, 2010.
13. United States Department of Health and Human Services. DHHS Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1 Infected Adults and Adolescents. DHHS; December 1, 2009:1-161. Available at: http://www.aidsinfo.nih. gov/ContentFiles/ AdultandAdolescentGL.pdf. Accessed May 27, 2010.
14. Kitahata MM, Gange SJ, Abraham AG, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009; 360:1815-1826.
15. Bae WH, Wester C, Smeaton LM, et al. Hematologic and hepatic toxicities associated with antenatal and postnatal exposure to maternal highly active antiretroviral therapy among infants. AIDS. 2008;22:1633-1640.
16. Stek AM. Antiretroviral medications during pregnancy for therapy or prophylaxis. Curr HIV/AIDS Rep. 2009;6:68-76.
17. WHO. Rapid advice: infant feeding in the context of HIV. 2009, Available at: http://www.who.int/hiv/pub/paediatric/advice/en/index.html. Accessed May 27, 2010.
18. El-Sadr WM, Grund B, Neuhaus J, et al. Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trial. Ann Intern Med. 2008;149:289-299.
19. Danel C, Moh R, Minga A, et al. CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial. Lancet. 2006;367:1981-1989.
20. Maggiolo F, Airoldi M, Callegaro A, et al. CD4 cell-guided scheduled treatment interruptions in HIV-infected patients with sustained immuno-logic response to HAART. AIDS. 2009;23:799-807.
21. Ananworanich J, Gayet-Ageron A, Le Braz M, et al. CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: results of the Staccato randomised trial. Lancet. 2006;368:459-465.
22. Watts DH, Lu M, Thompson B, et al. Treatment interruption after pregnancy: effects on disease progression and laboratory findings. Infect Dis Obstet Gynecol. 2009;2009:456717.
23. Onen NF, Nurutdinova D, Sungkanuparph S, et al. Effect of postpartum HIV treatment discontinuation on long-term maternal outcome. J Int Assoc Physicians AIDS Care (Chic Ill). 2008;7:245-251.
24. Nachega JB, Mills EJ, Schechter M. Antiretroviral therapy adherence and retention in care in middle-income and low-income countries: current status of knowledge and research priorities. Curr Opin HIVAIDS. 2010;5: 70-77.
25. ClinicalTrials.com, U.S. National Institutes of Health. Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited Countries (PROMISE); Available at: http://clinicaltrials. gov/ct2/show/NCT01061151. Accessed August 12, 2010.