Unrecognized pretransplant and donor-derived cryptococcal disease in organ transplant recipients

Clinical Infectious Diseases

Volumn 51, Issue 9, 2010, Pages 1062-1069

  Sun, Hsin Yun ^a,v   Alexander, Barbara D ^c   Lortholary, Olivier ^w   Dromer, Francoise ^x   Forrest, Graeme N ^d,r   Lyon, G Marshall ^e   Somani, Jyoti ^e   Gupta, Krishan L ^y   Del Busto, Ramon ^f   Pruett, Timothy L ^h   Sifri, Costi D ^h   Limaye, Ajit P ^j   John, George T ^z   Klintmalm, Goran B ^k   Pursell, Kenneth ^l   Stosor, Valentina ^m   Morris, Michele I ⁿ   Dowdy, Lorraine A ⁿ   Munoz, Patricia ^aa   Kalil, Andre C ^p   Garcia Diaz, Julia ^q   Orloff, Susan L ^r   House, Andrew A ^ab   Houston, Sally H ^o   Wray, Dannah ^s   Huprikar, Shirish ^t   Johnson, Leonard B ^g   Humar, Atul ^ac,ad   Razonable, Raymund R ^u   Fisher, Robert A ⁱ   Husain, Shahid ^b,ac   Wagener, Marilyn M ^b   Singh, Nina ^a,b   more..

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e EMORY UNIVERSITY   (United States)

^f HENRY FORD HOSPITAL   (United States)

^g St John Medical Center   (United States)

^h UNIVERSITY OF VIRGINIA   (United States)

ⁱ VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^j UNIVERSITY OF WASHINGTON   (United States)

^k BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^l UNIVERSITY OF CHICAGO   (United States)

^m NORTHWESTERN UNIVERSITY   (United States)

ⁿ UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^o TAMPA GENERAL HOSPITAL   (United States)

^p UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^q OCHSNER CLINIC FOUNDATION   (United States)

^r OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^s MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^t MOUNT SINAI MEDICAL CENTER   (United States)

^u MAYO CLINIC   (United States)

^v NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^w HÔPITAL NECKER ENFANTS MALADES   (France)

^x INSTITUT PASTEUR   (France)

^y POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^z CHRISTIAN MEDICAL COLLEGE   (India)

^aa HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^ab UNIVERSITY OF WESTERN ONTARIO   (Canada)

^ac TORONTO GENERAL HOSPITAL   (Canada)

^ad UNIVERSITY OF ALBERTA   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYPTOCOCCUS; DISEASE COURSE; FEMALE; FUNGEMIA; FUNGUS ISOLATION; GRAFT RECIPIENT; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; KIDNEY TRANSPLANTATION; LIVER BIOPSY; LIVER TRANSPLANTATION; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NONHUMAN; PRIORITY JOURNAL; PULMONARY CRYPTOCOCCOSIS;

EID: 77958603825     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/656584     Document Type: Article

References (28)

1. Husain S, Wagener MM, Singh N. Cryptococcus neoformans infection in organ transplant recipients: variables influencing clinical characteristics and outcome. Emerg Infect Dis 2001; 7:375-381.
2. Pappas PG, Alexander BD, Andes DR, et al. Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). Clin Infect Dis 2010; 50:1101-1111.
3. Sun HY, Wagener MM, Singh N. Cryptococcosis in solid-organ, hematopoietic stem cell, and tissue transplant recipients: evidence-based evolving trends. Clin Infect Dis 2009; 48:1566-1576.
4. Winston DJ, Emmanouilides C, Busuttil RW. Infections in liver transplant recipients. Clin Infect Dis 1995; 21:1077-1089; quiz 90-91.
5. Singh N, Husain S, De Vera M, Gayowski T, Cacciarelli TV. Cryptococcus neoformans infection in patients with cirrhosis, including liver transplant candidates. Medicine (Baltimore) 2004; 83:188-192.
6. Transplantation-transmitted tuberculosis - Oklahoma and Texas, 2007. MMWR Morb Mortal Wkly Rep 2008; 57:333-336.
7. Palacios G, Druce J, Du L, et al. A new arenavirus in a cluster of fatal transplant-associated diseases. N Engl J Med 2008; 358:991-998.
8. Srinivasan A, Burton EC, Kuehnert MJ, et al. Transmission of rabies virus from an organ donor to four transplant recipients. N Engl J Med 2005; 352:1103-1111. (Pubitemid 40365351)
9. Iwamoto M, Jernigan DB, Guasch A, et al. Transmission of West Nile virus from an organ donor to four transplant recipients. N Engl J Med 2003; 348:2196-2203.
10. Singh N, Alexander BD, Lortholary O, et al. Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality. J Infect Dis 2007; 195:756-764.
11. Sun HY, Alexander BD, Lortholary O, et al. Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis. Clin Infect Dis 2009; 49:1721-1728.
12. Ascioglu S, Rex JH, de Pauw B, et al. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 2002; 34:7-14.
13. Dromer F, Mathoulin-Pelissier S, Launay O, Lortholary O. Determinants of disease presentation and outcome during cryptococcosis: the CryptoA/D study. PLoS Med 2007; 4:e21.
14. Lortholary O, Poizat G, Zeller V, et al. Long-term outcome of AIDS-associated cryptococcosis in the era of combination antiretroviral therapy. AIDS 2006; 20:2183-2191.
15. Nicol AJ, Cassidy MJ, Michalowsky K, Kahn D. Use of intralipid as a vehicle for amphotericin B in the treatment of cryptococcal meningitis in a renal transplant recipient. Nephron 1996; 73:312-313. (Pubitemid 26159354)
16. Alexander J, Limaye AP, Ko CW, Bronner MP, Kowdley KV. Association of hepatic iron overload with invasive fungal infection in liver transplant recipients. Liver Transpl 2006; 12:1799-1804. (Pubitemid 44911806)
17. Fishman JA, Gonzalez RG, Branda JA. Case records of the Massachusetts General Hospital. Case 11-2008. A 45-year-old man with changes in mental status after liver transplantation. N Engl J Med 2008; 358:1604-1613.
18. Kanj SS, Welty-Wolf K, Madden J, et al. Fungal infections in lung and heart-lung transplant recipients: report of 9 cases and review of the literature. Medicine (Baltimore) 1996; 75:142-156. (Pubitemid 26159211)
19. Lu S, Furth EE, Blumberg EA, Bing Z. Hepatic involvement in a liver transplant recipient with disseminated cryptococcosis. Transpl Infect Dis 2009; 11:179-82.
20. Moe K, Lotsikas-Baggili AJ, Kupiec-Banasikowska A, Kauffman CL. The cutaneous predilection of disseminated cryptococcal infection in organ transplant recipients. Arch Dermatol 2005; 141:913-914. (Pubitemid 41058085)
21. Ooi BS, Chen BT, Lim CH, Khoo OT, Chan DT. Survival of a patient transplanted with a kidney infected with Cryptococcus neoformans. Transplantation 1971; 11:428-429.
22. Silveira FP, Husain S, Kwak EJ, et al. Cryptococcosis in liver and kidney transplant recipients receiving anti-thymocyte globulin or alemtuzumab. Transpl Infect Dis 2007; 9:22-27.
23. Xia D, Yan LN, Xu L, et al. Postoperative severe pneumonia in adult liver transplant recipients. Transplant Proc 2006; 38:2974-2978.
24. Singh N, Dromer F, Perfect JR, Lortholary O. Cryptococcosis in solid organ transplant recipients: current state of the science. Clin Infect Dis 2008; 47:1321-1327.
25. Saha DC, Goldman DL, Shao X, et al. Serologic evidence for reactivation of cryptococcosis in solid-organ transplant recipients. Clin Vaccine Immunol 2007; 14:1550-1554.
26. Ison MG, Hager J, Blumberg E, et al. Donor-derived disease transmission events in the United States: data reviewed by the OPTN/UNOS Disease Transmission Advisory Committee. Am J Transplant 2009; 9:1929-1935.
27. Singh N, Sun HY. Iron overload and unique susceptibility of liver transplant recipients to disseminated disease due to opportunistic pathogens. Liver Transpl 2008; 14:1249-1255.
28. Singh N, Aguado JM, Bonatti H, et al. Zygomycosis in solid organ transplant recipients: a prospective, matched case-control study to assess risks for disease and outcome. J Infect Dis 2009; 200:1002-1011.