Oral bioavailability and pharmacokinetic study of cetrizine HCl in Iranian healthy volunteers

Research in Pharmaceutical Sciences

Volumn 4, Issue 2, 2009, Pages 113-121

  Derakhshandeh, Katayoun ^a   Mohebbi, M ^a  

^a KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Bioequivalence; Cetrizine; HPLC; Pharmacokinetics

Indexed keywords

CETIRIZINE;

ADULT; ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD SAMPLING; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TABLET FORMULATION;

EID: 77958595955     PISSN: 17355362     EISSN: 17359414     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Hair PI, Scott LJ. Levocetirizine for the treatment of seasonal and perennial allergic rhinitis. Drugs. 2006;66:973-996.
2. Passalacqua G, Canonica GW. A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis. Clin Ther. 2005;27:979-992.
3. Bernheim J, Arendt C, de Vos C. Cetirizine: more than an antihistamine? Agents Actions Suppl. 1991;34:269-293.
4. Barnes CL, McKenzie CA, Webster KD, Poinsett-Holmes K. Cetirizine: a new, nonsedating antihistamine. Ann Pharmacother. 1993;27:464-470.
5. Anderson PO, Knoben JE, Troutman WG. Handbook of clinical drug data. 10th ed. New York: McGraw-Hill International; 2002. p. 807-810.
6. Tanigawara Y, Yamaoka K, Nakagawa T. New method for the evaluation of in vitro dissolution time and disintegration time. Chem Pharm Bull. 1982;30:1088-1090.
7. Stavchansky SA, McGinty JW. Bioavailability in tablet technology. In: Pharmaceutical dosage forms. Liberman HA., Lachman L, Schwartz JB, editors. New York: Dekker; 1989. p.349-564.
8. Costa OF, Sousa JJS, Pais AAC, Formosinho SJ. Comparison of dissolution profiles of ibuprofen pellets. J Control Release. 2003;89:199-212.
9. Bressolle F, Bromet-Petit M, Audran M. Validation of liquid chromatographic and gas chromatographic methods Application to pharmacokinetics. J Chromatogr B Biomed Sci Appl. 1996;686:3-10.
10. Causon R. Validation of chromatographic methods in biomedical analysis: viewpoint and discussion. J Chromatogr B Biomed Sci Appl. 1997;6898:175-180.
11. Wagner JG. Fundamentals of clinical pharmacokinetics. Hamilton IL: Drug Intelligence Publications; 1979. p. 173-201.
12. Shargel L, Wu-Pong S, Yu ABC. Applied biopharmaceutics and pharmacokinetics. 5th ed. New York: McGraw-Hill; 2004. p. 731-735.
13. Pandya KK, Bangaru RA, Gandhi TP, Modi IA, Modi RI, Chakravarthy BK. High-performance thinlayer chromatography for the determination of cetirizine in human plasma and its use in pharmacokinetic studies. J Pharm Pharmacol. 1996;48:510-513.
14. Kowalski P, Plenis A. Comparison of HPLC and CE methods for the determination of cetirizine dihydrochloride in human plasma samples. Biomed chromatogr. 2007;21:903-911.
15. Macek J, Ptácek P, Klíma J Determination of cetirizine in human plasma by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. 1994;736:231-235.
16. Nation RL, Sansom LN. Bioequivalence requirements for generic products. Pharmacol Ther. 1994;62:41-55.
17. Lefebvre RA, Rosseel MT, Bernheim J. Single dose pharmacokinetics of cetirizine in young and elderly volunteers. Int J Clin Pharmacol Res. 1988;8:463-470.
18. Matzke GR, Yeh J, Awni WM, Halstenson CE, Chung M. Pharmacokinetics of cetirizine in the elderly and patients with renal insufficiency. Ann Allergy. 1987;59:25-30.
19. Horsmans Y, Desager JP, Hulhoven R, Harvengt C. Single-dose pharmacokinetics of cetirizine in patients with chronic liver disease. J Clin Pharmacol. 1993;33:929-932. (Pubitemid 23304644)
20. Im H-T, Won J-H, Cho S-H, Lee H-W, Park W-S, Rew J-H, et al. Bioequivalence evaluation of two brands of cetirizine HCl 10 mg tablets (Zyrix and Zyrtec) in healthy male volunteers. J Kor Pharm Sci. 2005;35:355-360.
21. Peytavin G, Gautran C, Otoul C, Cremieux AC, Moulaert B, Delatour F, et al. Evaluation of pharmacokinetic interaction between cetirizine and ritonavir, an HIV-1 protease inhibitor, in healthy male volunteers. Eur J Clin Pharmacol. 2005;61:267-273.