Identification and quantitative determination of 4-hydroxyisoleucine in Trigonella foenum-graecum L. from Iran

Journal of Medicinal Plants

Volumn 9, Issue SUPPL 6., 2010, Pages 29-34

  Hajimehdipoor, H ^a,b   Sadat Ebrahimi, S E ^c   Amanzadeh, Y ^c   Izaddoost, M ^c   Givi, E ^a,c  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

4 hydroxyisoleucine; Amino acid; Diabetes; Trigonella foenum graecum

Indexed keywords

4 HYDROXYISOLEUCINE;

AMINO ACID ANALYSIS; ARTICLE; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; FENUGREEK; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; IRAN; PLANT SEED;

TRIGONELLA FOENUM-GRAECUM;

EID: 77958579105     PISSN: 2717204X     EISSN: 27172058     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Fenugreek seed bioactive compositions and methods for extracting same. United States Patent 7338675.
2. Morcos SR, Elhawary Z, Gabrial GN. Protein-rich food mixtures for feeding the young in egipt. 1. Formulation. Z. Ernahrungswiss 1981; 20: 275-82.
3. Basch E, Ulbricht C, Kuo G, Szapary Ph, Smith M. Therapeutic applications of Fenugreek. Altern. Med. Rev. 2003; 8 (1): 20-7.
4. Yoshikawa M, Murakami T, Komatsu H, Murakami N, Yamahara J, Matsuda H. Medicinal foodstuffs. IV. Fenugreek seed. (1): Structures of trigoneosides Ia, Ib, IIa, IIb and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum-graecum L. Chem. Pharm. Bull (Tokyo) 1997; 45: 81-7. (Pubitemid 27065834)
5. Amin Gh. Popular medicinal plants of Iran. Tehran: Vice-choncellor of Research of Tehran University of Medical Sciences, 1991, pp: 101-2.
6. Broca C, Breil V, Cruciani-Guglielmacci C, Manteghetti M, Rouault C, Derouet M, Rizkalla S, Pau B, Petit P, Ribes G, Ktorza A, Gross R, Reach G, Taouis M. Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat. Am. J. Physiol. Endocrinol. Metab. 2004; 287 (3): E463-E471.
7. Sauvaire Y, Petit P, Broca C, Manteghetti M, Baissac Y, Fernandez-Alvarez J, Gross R, Roye M, Leconte A, Gomis R, Ribes G. 4-hydroxyisileucine: a novel amino acid potentiator of insulin secretion. Diabetes 1998; 47 (2): 206-10.
8. Narender T, Puri A, Shweta, Khaliq T, Saxena R, Bhatia G, Chandra R. 4-hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent. Bioorg Med. Chem. Lett. 2006; 16 (2): 293-6. (Pubitemid 41680616)
9. Al-Habori M, Al-Aghbari AM, Al-Mamary M. Effects of fenugreek seeds and its extracts on plasma lipid profile: a study on rabbits. Phytother. Res. 1998; 12: 272-5.
10. Alcock NW, Crout DHG, Gregorio MVM, Lee E, Pike G, Samuel CJ. Stereochemistry of the 4-hydroxyisoleucine from Trigonella foenum graecum. Phytochem. 1989; 28 (7): 1835-41.
11. Rolland-Fulcrand V, Rolland M, Roumestant ML, Martinez J. Chemoenzymatic synthesis of Enantiomerically pure (2S,3R,4S)-4-hydroxyisoleucine, an insulinotropic amino acid isolated from fenugreek seeds. Eur. J. Org Chem. 2004; 873-7.
12. Harborne JB. Phytochemical methods. London: Chapman & Hall. 1998, pp: 190-2.
13. Tcherkas YV, Kartsova LA, Krasnova IN. Analysis of amino acids in human serum by isocratic reversed-phase high performance liquid chromatography with electrochemical detection. J. Chromatogr A. 2001; 913 (1-2): 303-8.
14. Gardner WS, St. John PA. High-performance liquid chromatographic method to determine ammonium ion and primary amines in seawater. Anal Chem. 1991; 63: 537-40.
15. Martinez-Force E, Benitez T. Separation of o-phthalaldehyde derivatives of amino acids of the internal pool of yeast by reverse-phase liquid chromatography. Biotechnol. Tech. 1991; 5 (3): 209-14.
16. United States Patent 5470879 1995, November 28.