Syncope caused by hyperkalemia during use of a combined therapy with the angiotensin-converting enzyme inhibitor and spironolactone

Kardiologia Polska

Volumn 68, Issue 9, 2010, Pages 1043-1045

  Erden, Ismail ^a   Yalcin, Subhan ^a   Ozhan, Hakan ^a  

^a DUZCE UNIVERSITY   (Turkey)

Author keywords

Aldosterone; Angiotensin converting enzyme inhibitors; Antagonist; Hyperkalemia; Syncope

Indexed keywords

ACETYLSALICYLIC ACID; ATORVASTATIN; CARVEDILOL; HYDROCHLOROTHIAZIDE; HYDROCHLOROTHIAZIDE PLUS RAMIPRIL; POTASSIUM; RAMIPRIL; SPIRONOLACTONE; UNCLASSIFIED DRUG;

AGED; ARTICLE; CASE REPORT; EDEMA; ELECTROCARDIOGRAM; FAMILY HISTORY; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERKALEMIA; HYPERTENSION; SINUS RHYTHM; SYNCOPE;

EID: 77958563925     PISSN: 00229032     EISSN: 00229032     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Pitt B, Zannad F, Remme W et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med, 1999; 341: 709-717. (Pubitemid 29407370)
2. Schepkens H, Vanholder R, Billiouw JM, Lameire N. Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone: an analysis of 25 cases. Am J Med, 2001; 110: 438-441.
3. th Ed. Mosby, St. Louis, MO 2002: 1730-1731.
4. Brosius FC, Hostetter TH, Kelepouris E et al. Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease. Circulation, 2006; 114: 1083-1087.
5. Bashour T, Hsu I, Gorfinkel HJ, Wickramesekaran R, Rios JC. Atrioventricular and intraventricular conduction in hyperkalemia. Am J Cardiol, 1975; 35: 199-203.
6. Kim NH, Oh SK, Jeong JW. Hyperkalaemia induced complete atrioventricular block with a narrow QRS complex. Heart, 2005; 91: e5.
7. Reardon LC, Macpherson DS. Hyperkalemia in outpatients using angiotensin-converting enzyme inhibitors. Arch Intern Med, 1998; 158: 26-32.
8. Juurlink DN, Mamdani MM, Lee DS et al. Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. N Engl J Med, 2004; 351: 543-551.