Computational analysis of HIV-1 protease protein binding pockets

Journal of Chemical Information and Modeling

Volumn 50, Issue 10, 2010, Pages 1759-1771

  Ko, Gene M ^a   Reddy, A Srinivas ^b   Kumar, Sunil ^a,c   Bailey, Barbara A ^a,d   Garg, Rajni ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UTC Aerospace Systems   (United States)

^d SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ANALYSIS; CONFORMATIONS; DATA MINING; DECISION TREES; DISCRIMINANT ANALYSIS; LOGISTIC REGRESSION; PROTEINS; RANDOM FORESTS;

BINDING CONFORMATIONS; CHEMICAL DESCRIPTORS; CLASSIFICATION TECHNIQUE; COMPUTATIONAL ANALYSIS; HIERARCHICAL CLASSIFICATION; HIV-1 PROTEASE INHIBITORS; LINEAR DISCRIMINANT ANALYSIS; OPTIMAL CLASSIFICATION;

CRYSTAL STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DATA MINING; ENZYMOLOGY; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DATA MINING; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 77958562342     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci100200u     Document Type: Article

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