Adult mesenchymal hamartoma of the liver: Case report and literature review

Case Reports in Gastroenterology

Volumn 4, Issue 1, 2010, Pages 84-92

  Klaassen, Zachary ^a,b   Paragi, Prakash R ^a   Chamberlain, Ronald S ^a,b,c,d  

^a SAINT BARNABAS MEDICAL CENTER   (United States)

^b St George's University   (Trinidad and Tobago)

^c University of Medicine and Dentistry of New Jersey   (United States)

^d NONE   (United States)

Author keywords

Hepatic mass; Hepatobiliary surgery; Mesenchymal hamartoma; Undifferentiated embryonal sarcoma

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN;

ABDOMINAL HYSTERECTOMY; ADULT; ARTICLE; BILE DUCT; BILE DUCT DILATATION; CASE REPORT; CHOLECYSTECTOMY; CLINICAL ASSESSMENT; COMPUTER ASSISTED TOMOGRAPHY; CYTOGENETICS; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HAMARTOMA; HEMANGIOMA; HISTOPATHOLOGY; HOSPITAL DISCHARGE; HUMAN; LIVER LOBECTOMY; LIVER TUMOR; MUSCLE DEVELOPMENT; OVARIECTOMY; PERCUTANEOUS BIOPSY; POSTOPERATIVE PERIOD; PRECANCER; PRIORITY JOURNAL; SMOOTH MUSCLE; SPINDLE CELL; STROMA; THYROIDECTOMY; TUMOR BIOPSY;

EID: 77958526628     PISSN: None     EISSN: 16620631     Source Type: Journal    
DOI: 10.1159/000260183     Document Type: Article

References (37)

1. Edmondson HA: Differential diagnosis of tumors and tumor-like lesions of liver in infancy and childhood. Am J Dis Child 1956;91:168-186.
2. Cook JR, Pfeifer JD, Dehner LP: Mesenchymal hamartoma of the liver in the adult: Association with distinct clinical features and histological changes. Hum Pathol 2002;33:893-898.
3. Lauwers GY, Grant LD, Donnelly WH, Meloni AM, Foss RM, Sanberg AA, Langham MR Jr: Hepatic undifferentiated (embryonal) sarcoma arising in a mesenchymal hamartoma. Am J Surg Pathol 1997;21:1248-1254.
4. Laberge JM, Patenaude Y, Desilets V, Cartier L, Khalife S, Jutras L, Chen MF: Large hepatic mesenchymal hamartoma leading to midtrimester fetal demise. Fetal Diagn Ther 2005;20:141-145.
5. Hernandez JC, Alfonso C, Gonzalez L, Samada M, Ramos L, Cepero-Valdez M, Antonio Abdo A, Gomez F, Castellanos R, Lopez O, Ugarte JC, Jordan J: Solid mesenchymal hamartoma in an adult: A case report. J Clin Pathol 2006;59:542-545.
6. Li O, Wang J, Sun Y, Cui Y, Hao X: Hepatic angiosarcoma arising in an adult mesenchymal hamartoma. Int Semin Surg Oncol 2007;4:3.
7. Mori R, Morioka D, Morioka K, Ueda M, Sugita M, Takeda K, Matsuo K, Tanaka K, Endo I, Sekido H, Togo S, Shimada H: Giant mesenchymal hamartoma of the liver in an adult. J Hepatobiliary Pancreat Surg 2008;15:667-669.
8. Yesim G, Gupse T, Zafer U, Ahmet A: Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients. J Hepatobiliary Pancreat Surg 2005;12:502-507.
9. Stocker J, Ishak KG: Mesenchymal hamartoma of the liver: report of 30 cases and review of the literature. Pediatr Pathol 1983;1:245-267.
10. Chau KY, Ho JW, Wu PC, Yuen WK: Mesenchymal hamartoma of liver in a man: Comparison with cases in infants. J Clin Pathol 1994;47:864-866.
11. Donovan TA, Wolverson MK, DeMello D, Craddock T, Silberstein M: Multicystic hepatic mesenchymal hamartoma of childhood: CT and US characteristics. Pediatr Radiol 1981;11:163-165.
12. Cetin M, Demirpolat G, Elmas N, Yuce G, Cetingul N, Balik E: Stromal predominant type mesenchymal hamartoma of liver: CT and MR features. Comput Med Imaging Graph 2002;26:167-169.
13. Mortele KJ, Ros PR: Cystic focal liver lesions in the adult: differential CT and MRI imaging features. Radiographics 2001;21:895-910.
14. Rajaram V, Knezevich S, Bove KE, Perry A, Pfeifer JD: DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation. Genes Chromosomes Cancer 2007;46:508-513.
15. Begueret H, Trouette H, Vielh P, Laurent C, MacGrogan G, Delsol M, Belleannee G, Masson B, De Mascarel A: Hepatic undifferentiated embryonal sarcoma: malignant evolution of mesenchymal hamartoma? Study of one case with immunohistochemical and flow cytometric emphasis. J Hepatol 2001;34:178-179.
16. O'Sullivan MJ, Swanson PE, Knoll J, Taboada EM, Dehner LP: Undifferentiated embryonal sarcoma with unusual features arising within mesenchymal hamartoma of the liver; report of a case and review of the literature. Pediatr Dev Pathol 2001;4:482-489.
17. Yamamura T, Kameyama Y, Hoshino T, Hayakawa K: A case of mesenchymal hamartoma of the liver coexisting with congenital dilatation of the bile duct. J Jpn Soc Clin Surg 1976;37:862.
18. Grases PJ, Matos-Villalobos M, Arcia-Romero F, Lecuna-Torres V: Mesenchymal hamartoma of the liver. Gastroenterology 1979;76:1466-1469.
19. Dooley JS, Li AKC, Scheuer PJ, Hobbs KEF, Sherlock S: A giant cystic mesenchymal hamartoma of the liver: Diagnosis, management, and study of cyst fluid. Gastroenterology 1983;85:958-961.
20. Kurokawa H, Sasaki K, Kamita N, Yamaguchi Y, Kikuchi Y, Kojimahara M: A case of huge hepatic hamartoma. Jpn J Clin Radiol 1984;29:901-904.
21. Ishizuka M, Miyashita M, Takahama M: A case of giant mesenchymal hamartoma of the liver found in an adult. Proc Jpn Cancer Assoc 1985;44:490.
22. Kawakami A, Fujii H, Ono Y: A case of hepatic mesenchymal hamartoma in an adult. Nippon Act Radiol 1986;46:1073.
23. Jennings CM, Merrill CR, Slater DN: Case report: The computed tomographic appearances of benign hepatic hamartoma. Clin Radiol 1987;38:103-104.
24. Kato Y, Yokozaki H: Hepatic mass (mesenchymal hamartoma). J Hiroshima Med Assoc 1988;41:143.
25. Gutierrez OH, Burgener FA: Mesenchymal hamartoma of the liver in an adult: radiologic diagnosis. Gastrointest Radiol 1988;13:341-344.
26. Gramlich TL, Killough BW, Garvin AJ: Mesenchymal hamartoma of the liver: Report of a case in a 28-year-old. Hum Pathol 1988;19:991-992.
27. Alanen A, Katevuo K, Toikkanen S: A non-cystic mesenchymal hamartoma of the liver-an unusual case of an unusual entity. Case report and review of the literature. Bildgebung 1989;56:181-184.
28. Ito Y, Seto Y, Okano H, Ueda T, Imanishi H, Nakamura K, Nakajima T, Okanoue T: A case of mesenchymal hamartoma of the liver in adult woman with pancreas divisum and marked delay in ICG plasma clearance. Nippon Shokakibyo Gakkai Zasshi 1989;86:1534-1539.
29. Urabe S, Furukawa M, Nakata T: A case of mesenchymal hamartoma of the liver in an adult. Jpn J Gastroenterol Surg 1990;23:664.
30. Drachenberg CB, Papadimitriou JC, Rivero MA, Wood C: Adult mesenchymal hamartoma of the liver: Report of a case with light microscopic, FNA cytology, immunohistochemistry, and ultrastructural studies and review of the literature. Mod Pathol 1991;4:392-395.
31. Wada M, Ohashi E, Jin H, Nishikawa M, Shintani S, Yamashita M, Kano M, Yamanaka N, Nishigami T, Shimoyama T: Mesenchymal hamartoma of the liver: report of an adult case and review of the literature. Inter Med 1992;31:1370-1375.
32. Megremis S, Sfakianaki E, Voludaki A, Chroniaris N: The ultrasonographic appearance of a cystic mesenchymal hamartoma of the liver observed in a middleaged woman. J Clin Ultrasound 1994;22:338-341.
33. Chung JH, Cho KJ, Choi DW, Lee BH, Chi JG: Solid mesenchymal hamartoma of the liver in adult. J Korean Med Sci 1999;14:335-337.
34. Papastratis G, Margaris H, Zografos GN, Korkolis D, Mannika Z: Mesenchymal hamartoma of the liver in an adult: a review of the literature. Int J Clin Pract 2000;54:552-554.
35. Brkic T, Hrstic I, Vucelic B, Jakic-Razumovic J, Skegro M, Romic B, Cukovic-Cavka S, Pulanic R, Ostojic R: Benign mesenchymal liver hamartoma in an adult male: a case report and review of the literature. Acta Med Austriaca 2003;30:134-137.
36. Kim MH, Choi MS, Lee JH, Koh KC, Paik SW, Yoo BC, Jung JH, Choi SC, Kim DH, Lee H, Song BG, Rhee JC, Park CG: Mesenchymal hamartoma of the liver in adults. Taehan Kan Hakhoe Chi 2003;9:31-34.
37. Ayadi-Kaddour A, Saiji E, Ben Slama S, Chelly-Ennaiffer I, Lahmar-Boufaroua A, Goutallier-Ben Fadhel C, Ben Sassi L, Khalfallah MT, Mzabi-Regaya S: Hepatic mesenchymal hamartoma in adulthood: a case report with literature review. Tunis Med 2006;84:263-265.