A rapid and reliable UPLC-MS/MS method for the identification and quantification of fourteen synthetic anti-diabetic drugs in adulterated Chinese proprietary medicines and dietary supplements

Biomedical Chromatography

Volumn 24, Issue 11, 2010, Pages 1255-1261

  Li, Ning ^a   Cui, Mei ^a   Lu, Xiumei ^a   Qin, Feng ^a   Jiang, Kun ^a   Li, Famei ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Adulteration; Anti diabetic drugs; Chinese proprietary medicines; Dietary supplements; UPLC MS MS

Indexed keywords

ELECTROSPRAY IONIZATION; FOOD ADDITIVES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUTRITION; ULTRASONIC APPLICATIONS; VITAMINS;

ADULTERATION; ANTIDIABETIC DRUG; CHINESE PROPRIETARY MEDICINE; GRADIENT ELUTION; MOBILE PHASIS; PROTONATED MOLECULES; QUALITATIVE AND QUANTITATIVE ANALYSIS; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRIES; ULTRASONIC EXTRACTION; UPLC-MS/MS;

DIETARY SUPPLEMENTS;

ACETONITRILE; ANTIDIABETIC AGENT; CHINESE DRUG; CHLORPROPAMIDE; FORMIC ACID; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; GLIPIZIDE; GLIQUIDONE; METFORMIN; METHANOL; MITIGLINIDE; NATEGLINIDE; PHENFORMIN; PIOGLITAZONE; REPAGLINIDE; ROSIGLITAZONE; TOLBUTAMIDE; WATER;

ACCURACY; ARTICLE; COLUMN CHROMATOGRAPHY; CORRELATION COEFFICIENT; DIET SUPPLEMENTATION; DRUG STRUCTURE; ELECTROSPRAY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SAMPLING; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

EID: 77958513239     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1438     Document Type: Article

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