Development of a validated LC method for enantiomeric separation and determination of adrafinil and its related substances on a Chiralcel OJ-H column connected to PDA and polarimetric detectors in series

Biomedical Chromatography

Volumn 24, Issue 11, 2010, Pages 1228-1233

  Rao, R Nageswara ^a   Maurya, Pawan K ^a   Shinde, Dhananjay D ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Adrafinil; Chiralcel OJ H; Enantiomeric purity; Impurity profile; Psychostimulants

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; ENANTIOMERS; HEXANE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ADRAFINIL; CHIRALCEL OJ-H; ENANTIOMERIC DETERMINATION; ENANTIOMERIC PURITY; ENANTIOMERIC SEPARATION; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHODS; IMPURITY PROFILE; PHOTODIODE ARRAYS; PSYCHOSTIMULANTS; RELATED SUBSTANCES;

QUALITY ASSURANCE;

ADRAFINIL;

ACCURACY; ANALYTIC METHOD; ARTICLE; COLUMN CHROMATOGRAPHY; DRUG STRUCTURE; ENANTIOMER; LIQUID CHROMATOGRAPHY; OPTICAL ROTATION; PHOTODIODE ARRAY; POLARIMETRY; PROCESS CONTROL; QUALITY CONTROL; SEPARATION TECHNIQUE; VALIDATION STUDY;

EID: 77958504088     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1432     Document Type: Article

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