On the design of polymeric 5′-O-ester prodrugs of 3′-azido-2′,3′-dideoxythymidine (AZT)

Tetrahedron Letters

Volumn 51, Issue 47, 2010, Pages 6123-6125

  Troev, Kolio D ^a   Mitova, Violeta A ^a   Ivanov, Ivan G ^b  

^a INSTITUTE OF POLYMERS   (Bulgaria)

^b BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

Author keywords

Anti HIV prodrugs; AZT; Poly(oxyethylene H phosphonate)s; Polymer conjugates; Toxicity

Indexed keywords

NUCLEOSIDE ANALOG; POLY(5' O 3' AZIDO 2',3' DIDEOXYTHYMIDINE OXYETHYLENE PHOSPHATE); PRODRUG; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; GEL PERMEATION CHROMATOGRAPHY; IC 50; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ROOM TEMPERATURE; STRUCTURE ACTIVITY RELATION;

EID: 77958498186     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.09.076     Document Type: Article

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