Helicase-inactivating mutations as a basis for dominant negative phenotypes

Cell Cycle

Volumn 9, Issue 20, 2010, Pages 4080-4090

  Wu, Yuliang ^a   Brosh Jr , Robert M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

DNA repair; Dominant lethal; Dominant negative; FANCJ; Fanconi anemia; G quadruplex; Genomic stability; Helicase; Human disease; Replication

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BRCA1 PROTEIN; CELL DNA; CHECKPOINT KINASE RAD3; DNA BINDING PROTEIN; DNA POLYMERASE; DNAB HELICASE; FANCONI ANEMIA PROTEIN; NIBRIN; SINGLE STRANDED DNA;

APOPTOSIS; CHROMOSOMAL INSTABILITY; DNA CROSS LINKING; DNA DAMAGE; DNA METABOLISM; DNA PROTEIN COMPLEX; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; ENZYME ACTIVITY; ESCHERICHIA COLI; FANCONI ANEMIA; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC CODE; GENETIC STABILITY; HUMAN; MISSENSE MUTATION; MORTALITY; NONHUMAN; PHENOTYPE; REVIEW; SACCHAROMYCES CEREVISIAE; WERNER SYNDROME;

EID: 77958491662     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.20.13667     Document Type: Review

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