Soft core-shell polymeric nanoparticles with magnetic property for potential guided drug delivery

Current Nanoscience

Volumn 6, Issue 5, 2010, Pages 483-491

  Sahingr, Nurettin ^a   Ilsin, Pingar ^a  

^a ÇANAKKALE ONSEKIZ MART UNIVERSITY   (Turkey)

Author keywords

Drug release; Magnetic; Microgel; Multifunctional; Nanocomposites; Soft nanoparticles

Indexed keywords

ACRYLIC MONOMERS; AMIDES; AMMONIUM PERSULFATE; CROSSLINKING; DRUG PRODUCTS; ETHYLENE; ETHYLENE GLYCOL; HYDROPHILICITY; IRON OXIDES; MAGNETITE; MICROEMULSIONS; NANOCOMPOSITES; NANOMAGNETICS; NANOPARTICLES; POLYMER BLENDS; POLYMERIZATION; SHELLS (STRUCTURES); SWELLING; TARGETED DRUG DELIVERY;

DRUG RELEASE; ETHYLENE GLYCOL DIMETHACRYLATE; LOWER CRITICAL SOLUTION TEMPERATURE; MAGNETIC; MICROEMULSION POLYMERIZATION; MICROGEL; MULTIFUNCTIONAL; PHOSPHATE BUFFER SOLUTIONS;

CONTROLLED DRUG DELIVERY;

ACRYLONITRILE; DRUG CARRIER; FERRITE; NANOPARTICLE; PHOSPHATE BUFFERED SALINE; POLY(N ISOPROPYLACRYLAMIDE); VERAPAMIL;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG RELEASE; HYDROPHILICITY; IN VITRO STUDY; MICROEMULSION; POLYMERIZATION; PRECIPITATION; PRIORITY JOURNAL; ROOM TEMPERATURE;

EID: 77958485545     PISSN: 15734137     EISSN: None     Source Type: Journal    
DOI: 10.2174/157341310797574998     Document Type: Article

References (18)

1. Liu, T.Y.; Hu, S.H.; Liu, D.M.; Chen, S.Y.; Chen, I.-W. Biomedical nanoparticle carriers with combined thermal and magnetic responses-A review. Nano Today, 2009, 4, 52-65.
2. Modak, N.; Datta, A.; Ganguly, R. Cell separation in a microfluidic channel using magnetic microspheres. Microfluid Nanofluid, 2009, 6, 647-660.
3. Sauzedde, F.; Elaissari, A.; Pichot, C. Thermosensitive magnetic particles as solid phase support in an immunoassay. Macromol. Symp., 2000, 151, 617-623.
4. Koneracka, M.; Kopcansky, P.; Antalik, M.; Timko, M.; Ramchand, C.N.; Lobo, D.; Mehta, R.V.; Upadhyay, R.V. Immobilization of proteins and enzymes to fine magnetic particles. J. Magn. Magn. Mater., 1999, 201, 427-430.
5. Zhang, J.; Misra, R.D.K. Magnetic drug-targeting carrier encapsulated with thermosensitive smart polymer: core-shell nanoparticle carrier and drug release response. Acta Biomater., 2007, 3, 838-850.
6. Brazel, C.S. Magnetothermally-responsive nanomaterials: combining magnetic nanostructures and thermally-sensitive polymers for triggered drug release. Pharm. Res., 2009, 26, 3.
7. Horecha, M.; Senkovsky, V.; Stamm, M.; Kiriy, A. One-pot synthesis of thermoresponsive PNIPAM hydrogel microcapsules designed to function in apolar media. Macromolecules, 2009, 42, 5811-5817.
8. Bawa, P.; Pillay, V.; Choonara, Y.E.; du Toit, L.C. Stimuli-responsive polymers and their applications in drug delivery. Biomed. Mater., 2009, 4(02), 2001.
9. Chen, H.; Liu, L.H.; Wang, L.S.; Ching, C.B.; Yu, H.W.; Yang Y.Y. Thermally responsive reversed micelles for immobilization of enzymes. Adv. Funct. Mater., 2008, 18, 95-102.
10. Sahiner, N.; Alb, A.M.; Graves, R.; Mandal, T.; McPherson, G.L.; Reed, W.F.; John, V.T. Core-shell nanohydrogel structures as tunable delivery systems. Polymer, 2007, 48, 704-711.
11. Sahiner, N. Hydrogel nanonetworks with functional core-shell structure. Eur. Polym. J., 2007, 43, 1709-1717.
12. Goya, G.F.; Grazu, V.; Ibarra, M.R. Magnetic nanoparticles for cancer therapy. Curr. Nanosci., 2008, 4, 1-16.
13. Liu, X.; Ma, Z.; Xing, J.; Liu, H. Preparation and characterization of amino silane modified superparamagnetic silica nanospheres. J. Magn. Magn. Mater., 2004, 270, 1-6.
14. Sahiner, N.; Pekel, N.; Guven, O. Radiation synthesis of N-vinyl 2-Pyrrolidone/Acrylonitrile interpenetrating polymer networks and their use in uranium recovery from aqueous systems. Radiat. Phys. Chem., 1998, 52(1-6), 271-276.
15. Zhou, G.; Elaissari, A.; Delair, T.; Pichot, C. Synthesis and characterization of surface-cyanofunctionalized poly (N-isopropylacrylamide) latexes. Coll. Polym. Sci., 1998, 276, 1131-1139.
16. Peltonen, L.; Hirvonen, J. Physicochemical characterization of nano- and microparticles. Curr. Nanosci., 2008, 4, 101-107.
17. Subramani, K.; Hosseinkhani, H.; Khraisat, A.; Hosseinkhani, M.; Pathak, Y. Targeting nanoparticles as drug delivery systems for cancer treatment. Curr. Nanosci., 2009, 5, 135-140.
18. Yang, W.-Z.; Chen, H.-L.; Gao, F.-P.; Chen, M.-M.; Li, X.-M.; Zhang, M.-M; Zhang, Q.-Q.; Liu, L.-R.; Jiang, Q.; Wang, Y.-S. Self-aggregated nanoparticles of cholesterol-modified pullulan conjugate as a novel carrier of mitoxantronep. Curr. Nanosci., 2010, 6, 298-306.