메뉴 건너뛰기
Expert Opinion on Therapeutic Patents
Volumn 20, Issue 11, 2010, Pages 1603-1607
Methods for synthesis and uses of inhibitors of Ghrelin O-acyltransferase inhibitors as potential therapeutic agents for obesity and diabetes
Author keywords

diabetes; enzyme inhibition; ghrelin O acyltransferase; obesity
Indexed keywords

ACYLTRANSFERASE; ACYLTRANSFERASE INHIBITOR; GHRELIN; GHRELIN O ACYLTRANSFERASE; GHRELIN O ACYLTRANSFERASE INHIBITOR; GLUCOSE; GO COA TAT; INSULIN; UNCLASSIFIED DRUG; YIL 781; YIL 870;
EID: 77958475385     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.2011.527333     Document Type: Short Survey
Times cited : (2)
References (9)
  • 1
    • 71849109389 scopus 로고    scopus 로고
    • Lean mean fat reducing "ghrelin" machine: Hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity
    • Schellekens H, Dinan TG, Cryan JF. Lean mean fat reducing "ghrelin" machine: Hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity. Neuropharmacology 2010;58:2-16
    • (2010) Neuropharmacology , vol.58 , pp. 2-16
    • Schellekens, H.1    Dinan, T.G.2    Cryan, J.F.3
  • 2
    • 77953426150 scopus 로고    scopus 로고
    • Ghrelin receptor modulators and their therapeutic potential
    • Costantino L, Barlocco D. Ghrelin receptor modulators and their therapeutic potential. Future Med Chem 2009;1:157-77
    • (2009) Future Med Chem , vol.1 , pp. 157-77
    • Costantino, L.1    Barlocco, D.2
  • 3
    • 35548949948 scopus 로고    scopus 로고
    • Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
    • Esler WP, Rudolph J, Claus TH, et al. Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss. Endocrinology 2007;148:5175-85
    • (2007) Endocrinology , vol.148 , pp. 5175-85
    • Esler, W.P.1    Rudolph, J.2    Claus, T.H.3
  • 4
    • 33646090850 scopus 로고    scopus 로고
    • 2, 4-Diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists
    • Serby MD, Zhao H, Szczepankiewicz BG, et al. 2,4-Diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists. J Med Chem 2006;49:2568-78
    • (2006) J Med Chem , Issue.49 , pp. 2568-78
    • Serby, M.D.1    Zhao, H.2    Szczepankiewicz, B.G.3
  • 5
    • 77954127564 scopus 로고    scopus 로고
    • GOAT: The master switch fort the ghrelin system?
    • Romero A, Kirchner H, Heppner K, et al. GOAT: the master switch fort the ghrelin system? Eur J Endocrinol 2010;163:1-8
    • (2010) Eur J Endocrinol , vol.163 , pp. 1-8
    • Romero, A.1    Kirchner, H.2    Heppner, K.3
  • 6
    • 49449085708 scopus 로고    scopus 로고
    • Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides
    • Yang J, Zhao TJ, Goldstein JL, Brown MS. Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides. Proc Natl Acad Sci USA 2008;105:10750-5
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10750-5
    • Yang, J.1    Zhao, T.J.2    Goldstein, J.L.3    Brown, M.S.4
  • 7
    • 77958466369 scopus 로고    scopus 로고
    • UniversityofTexas. US2010/0086955A1
    • UniversityofTexas. US2010/0086955A1; 2010
    • (2010)
  • 9
    • 71749110589 scopus 로고    scopus 로고
    • Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling
    • Kilk K, Mahlapuu R, Soomets U, Langel U. Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling. Toxicology 2009;265:87-95
    • (2009) Toxicology , vol.265 , pp. 87-95
    • Kilk, K.1    Mahlapuu, R.2    Soomets, U.3    Langel, U.4

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.