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Volumn 28, Issue 11, 2010, Pages 2342-2350

Antihypertensive efficacy and safety of olmesartan medoxomil and ramipril in elderly patients with mild to moderate essential hypertension: The ESPORT study

Author keywords

ambulatory blood pressure monitoring; elderly; essential hypertension; office blood pressure; olmesartan; ramipril

Indexed keywords

OLMESARTAN; PLACEBO; RAMIPRIL;

EID: 77958463672     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e32833e116b     Document Type: Article
Times cited : (41)

References (42)
  • 2
    • 0021864792 scopus 로고
    • Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial
    • Amery A, Birkenhäger W, Brixko P, Bulpitt C, Clement D, Deruyttere M, et al. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. Lancet 1985; 1:1349-1354.
    • (1985) Lancet , vol.1 , pp. 1349-1354
    • Amery, A.1    Birkenhäger, W.2    Brixko, P.3    Bulpitt, C.4    Clement, D.5    Deruyttere, M.6
  • 3
    • 0022469583 scopus 로고
    • Randomized trial of treatment of hypertension in elderly patients in primary care
    • Coope J, Warrender TS. Randomized trial of treatment of hypertension in elderly patients in primary care. Br Med J (Clin Res Ed) 1986; 293:1145-1151.
    • (1986) Br Med J (Clin Res Ed) , vol.293 , pp. 1145-1151
    • Coope, J.1    Warrender, T.S.2
  • 4
    • 0025831464 scopus 로고
    • Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension
    • Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group
    • Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group. JAMA 1991; 265:3255-3264.
    • (1991) JAMA , vol.265 , pp. 3255-3264
  • 5
    • 0025942936 scopus 로고
    • Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)
    • Dahlöf B, Lindholm LH, Hansson L, Scherstén B, Ekbom T, Wester PO. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 1991; 338:1281-1285.
    • (1991) Lancet , vol.338 , pp. 1281-1285
    • Dahlöf, B.1    Lindholm, L.H.2    Hansson, L.3    Scherstén, B.4    Ekbom, T.5    Wester, P.O.6
  • 6
    • 0026512315 scopus 로고
    • Medical Research Council trial of treatment of hypertension in older adults: Principal results. MRC Working Party
    • Medical Research Council trial of treatment of hypertension in older adults: principal results. MRC Working Party. BMJ 1992; 304:405-412.
    • (1992) BMJ , vol.304 , pp. 405-412
  • 7
    • 0029830418 scopus 로고    scopus 로고
    • Shanghai trial of nifedipine in the elderly (STONE)
    • Gong L, Zhang W, Zhu Y, Zhu J, Kong D, Pagé V, et al. Shanghai trial of nifedipine in the elderly (STONE). J Hypertens 1996; 14:1237-1245.
    • (1996) J Hypertens , vol.14 , pp. 1237-1245
    • Gong, L.1    Zhang, W.2    Zhu, Y.3    Zhu, J.4    Kong, D.5    Pagé, V.6
  • 8
    • 0343487983 scopus 로고    scopus 로고
    • Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators
    • Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG, Birkenhäger WH, etal. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet 1997; 350:757-764.
    • (1997) Lancet , vol.350 , pp. 757-764
    • Staessen, J.A.1    Fagard, R.2    Thijs, L.3    Celis, H.4    Arabidze, G.G.5    Birkenhäger, W.H.6
  • 9
    • 0034707686 scopus 로고    scopus 로고
    • Chinese trial on isolated sistoli hypertension in the elderly
    • Systolic Hypertension in China (Syst-China) Collaborative Group
    • Wang JG, Staessen JA, Gong L, Liu L. Chinese trial on isolated sistoli hypertension in the elderly. Systolic Hypertension in China (Syst-China) Collaborative Group. Arch Intern Med 2000; 160:211-220.
    • (2000) Arch Intern Med , vol.160 , pp. 211-220
    • Wang, J.G.1    Staessen, J.A.2    Gong, L.3    Liu, L.4
  • 11
    • 22844448780 scopus 로고    scopus 로고
    • Hypertension in adults across the age spectrum: Current outcomes and control in the community
    • Lloyd-Jones DM, Evans JC, Levy D. Hypertension in adults across the age spectrum: current outcomes and control in the community. JAMA 2005; 294:466-472.
    • (2005) JAMA , vol.294 , pp. 466-472
    • Lloyd-Jones, D.M.1    Evans, J.C.2    Levy, D.3
  • 12
    • 34347377582 scopus 로고    scopus 로고
    • Trends in hypertension prevalence, awareness, treatment, and control in older U.S. adults: Data from the National Health and Nutrition Examination Survey 1988 to 2004
    • Ostchega Y, Dillon CF, Hughes JP, Carroll M, Yoon S. Trends in hypertension prevalence, awareness, treatment, and control in older U.S. adults: data from the National Health and Nutrition Examination Survey 1988 to 2004. J Am Geriatr Soc 2007; 55:1056-1065.
    • (2007) J Am Geriatr Soc , vol.55 , pp. 1056-1065
    • Ostchega, Y.1    Dillon, C.F.2    Hughes, J.P.3    Carroll, M.4    Yoon, S.5
  • 13
    • 69349103215 scopus 로고    scopus 로고
    • Shattuck Lecture. The hypertension paradox: More uncontrolled disease despite improved therapy
    • Chobanian AV. Shattuck Lecture. The hypertension paradox: more uncontrolled disease despite improved therapy. N Engl J Med 2009; 361:878-887.
    • (2009) N Engl J Med , vol.361 , pp. 878-887
    • Chobanian, A.V.1
  • 14
  • 16
    • 67449135756 scopus 로고    scopus 로고
    • Drug treatment of hypertension in older hypertensives
    • Rashidi A, Wright JT Jr. Drug treatment of hypertension in older hypertensives. Clin Geriatr Med 2009; 25:235-244.
    • (2009) Clin Geriatr Med , vol.25 , pp. 235-244
    • Rashidi, A.1    Wright Jr., J.T.2
  • 17
    • 44349101152 scopus 로고    scopus 로고
    • Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: Meta-analysis of randomised trials
    • Turnbull F, Neal B, Ninomiya T, Algert C, Arima H, Barzi F, et al. Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. BMJ 2008; 336:1121-1123.
    • (2008) BMJ , vol.336 , pp. 1121-1123
    • Turnbull, F.1    Neal, B.2    Ninomiya, T.3    Algert, C.4    Arima, H.5    Barzi, F.6
  • 18
    • 67650082354 scopus 로고    scopus 로고
    • Use of blood pressure lowering drugs in the prevention of cardiovascular disease: Meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
    • Law MR, Morris JK, Wald NJ. Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. BMJ 2009; 338:b1665.
    • (2009) BMJ , vol.338
    • Law, M.R.1    Morris, J.K.2    Wald, N.J.3
  • 19
    • 70449851433 scopus 로고    scopus 로고
    • Reappraisal of European guidelines on hypertension management: A European Society of Hypertension Task Force document
    • Mancia G, Laurent S, Agabiti-Rosei E, Ambrosioni E, Burnier M, Caulfield MJ, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens 2009; 27:2121-2158.
    • (2009) J Hypertens , vol.27 , pp. 2121-2158
    • Mancia, G.1    Laurent, S.2    Agabiti-Rosei, E.3    Ambrosioni, E.4    Burnier, M.5    Caulfield, M.J.6
  • 20
    • 66949148736 scopus 로고    scopus 로고
    • Now or never: Optimal antihypertensive therapy in the elderly
    • Prisant LM. Now or never: optimal antihypertensive therapy in the elderly. Prev Cardiol 2008; 11:201-209.
    • (2008) Prev Cardiol , vol.11 , pp. 201-209
    • Prisant, L.M.1
  • 21
    • 3242674468 scopus 로고    scopus 로고
    • Comparison of valsartan 160 mg with lisinopril 20 mg, given as monotherapy or in combination with a diuretic, for the treatment of hypertension: The blood pressure reduction and tolerability of valsartan in comparison with lisinopril (PREVAIL) study
    • DOI 10.1016/S0149-2918(04)90129-4, PII S0149291804901294
    • Malacco E, Santonastaso M, Varì NA, Gargiulo A, Spagnuolo V, Bertocchi F, Palatini P, Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril Study. Comparison of valsartan 160mg with lisinopril 20 mg, given as monotherapy or in combination with a diuretic, for the treatment of hypertension: the Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril (PREVAIL) study. Clin Ther 2004; 26:855-865. (Pubitemid 38943034)
    • (2004) Clinical Therapeutics , vol.26 , Issue.6 , pp. 855-865
    • Malacco, E.1    Santonastaso, M.2    Vari, N.A.3    Gargiulo, A.4    Spagnuolo, V.5    Bertocchi, F.6    Palatini, P.7
  • 22
    • 69549116316 scopus 로고    scopus 로고
    • Antihypertensive efficacy of telmisartan vs ramipril over the 24-h dosing period, including the critical early morning hours: A pooled analysis of the PRISMA i and II randomized trials
    • Williams B, Lacourcière Y, Schumacher H, Gosse P, Neutel JM. Antihypertensive efficacy of telmisartan vs ramipril over the 24-h dosing period, including the critical early morning hours: a pooled analysis of the PRISMA I and II randomized trials. J Hum Hypertens 2009; 23:610-619.
    • (2009) J Hum Hypertens , vol.23 , pp. 610-619
    • Williams, B.1    Lacourcière, Y.2    Schumacher, H.3    Gosse, P.4    Neutel, J.M.5
  • 23
    • 0028806022 scopus 로고
    • Efficacy and tolerability of losartan versus enalapril alone or in combination with hydrochlorothiazide in patients with essential hypertension
    • Townsend R, Haggert B, Liss C, Edelman JM. Efficacy and tolerability of losartan versus enalapril alone or in combination with hydrochlorothiazide in patients with essential hypertension. Clin Ther 1995; 17:911-923.
    • (1995) Clin Ther , vol.17 , pp. 911-923
    • Townsend, R.1    Haggert, B.2    Liss, C.3    Edelman, J.M.4
  • 24
    • 0032896412 scopus 로고    scopus 로고
    • Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension
    • Neutel JM, Frishman WH, Oparil S, Papademitriou V, Guthrie G. Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension. Am J Ther 1999; 6:161-166.
    • (1999) Am J Ther , vol.6 , pp. 161-166
    • Neutel, J.M.1    Frishman, W.H.2    Oparil, S.3    Papademitriou, V.4    Guthrie, G.5
  • 25
    • 0033736285 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind study of the antihypertensive efficacy and tolerability of irbesartan in patients aged or65 years with mild to moderate hypertension
    • Lacourcière Y. A multicenter, randomized, double-blind study of the antihypertensive efficacy and tolerability of irbesartan in patients aged or65 years with mild to moderate hypertension. Clin Ther 2000; 22:1213-1224.
    • (2000) Clin Ther , vol.22 , pp. 1213-1224
    • Lacourcière, Y.1
  • 26
    • 0035215475 scopus 로고    scopus 로고
    • Eprosartan versus enalapril in elderly patients with hypertension: A double-blind, randomized trial
    • Ruilope L, Jäger B, Prichard B. Eprosartan versus enalapril in elderly patients with hypertension: a double-blind, randomized trial. Blood Press 2001; 10:223-229.
    • (2001) Blood Press , vol.10 , pp. 223-229
    • Ruilope, L.1    Jäger, B.2    Prichard, B.3
  • 28
    • 44949171907 scopus 로고    scopus 로고
    • Olmesartan medoxomil: A review of its use in the management of hypertension
    • Scott LJ, McCormack PL. Olmesartan medoxomil: a review of its use in the management of hypertension. Drugs 2008; 68:1239-1272.
    • (2008) Drugs , vol.68 , pp. 1239-1272
    • Scott, L.J.1    McCormack, P.L.2
  • 29
    • 58149129126 scopus 로고    scopus 로고
    • Olmesartan medoxomil in elderly patients with essential or isolated systolic hypertension: Efficacy and safety data from clinical trials
    • Heagerty AM, Mallion JM. Olmesartan medoxomil in elderly patients with essential or isolated systolic hypertension: efficacy and safety data from clinical trials. Drugs Aging 2009; 26:61-76.
    • (2009) Drugs Aging , vol.26 , pp. 61-76
    • Heagerty, A.M.1    Mallion, J.M.2
  • 30
    • 34748894914 scopus 로고    scopus 로고
    • Systolic blood pressure reduction with olmesartan medoxomil versus nitrendipine in elderly patients with isolated systolic hypertension
    • Mallion JM, Heagerty A, Laeis P. Systolic blood pressure reduction with olmesartan medoxomil versus nitrendipine in elderly patients with isolated systolic hypertension. J Hypertens 2007; 25:2168-2177.
    • (2007) J Hypertens , vol.25 , pp. 2168-2177
    • Mallion, J.M.1    Heagerty, A.2    Laeis, P.3
  • 31
    • 0035992025 scopus 로고    scopus 로고
    • Working group on blood pressure monitoring of the European Society of Hypertension International Protocol for validation of blood pressure measuring devices in adults
    • O'Brien E, Pickering T, Asmar R, Myers M, Parati G, Staessen J, et al. Working group on blood pressure monitoring of the European Society of Hypertension International Protocol for validation of blood pressure measuring devices in adults. Blood Press Monit 2002; 7:3-17.
    • (2002) Blood Press Monit , vol.7 , pp. 3-17
    • O'Brien, E.1    Pickering, T.2    Asmar, R.3    Myers, M.4    Parati, G.5    Staessen, J.6
  • 32
    • 58949094691 scopus 로고    scopus 로고
    • Italian society of hypertension guidelines for conventional and automated blood pressure measurement in the office, at home and over 24 hours
    • Parati G, Omboni S, Palatini P, Rizzoni D, Bilo G, Valentini M, et al. Italian Society of Hypertension Guidelines for Conventional and Automated Blood Pressure Measurement in the Office, at Home and Over 24 Hours. High Blood Press Cardiovasc Prev 2008; 15:283-310.
    • (2008) High Blood Press Cardiovasc Prev , vol.15 , pp. 283-310
    • Parati, G.1    Omboni, S.2    Palatini, P.3    Rizzoni, D.4    Bilo, G.5    Valentini, M.6
  • 33
    • 0000203496 scopus 로고    scopus 로고
    • Beyond trough:peak ratio: A new index of the smoothness of the antihypertensive effect of a drug
    • Rizzoni D, Castellano M, Muiesan ML, Porteri E, Agabiti-Rosei E. Beyond trough:peak ratio: a new index of the smoothness of the antihypertensive effect of a drug. High Blood Press 1997; 6:110-115.
    • (1997) High Blood Press , vol.6 , pp. 110-115
    • Rizzoni, D.1    Castellano, M.2    Muiesan, M.L.3    Porteri, E.4    Agabiti-Rosei, E.5
  • 34
    • 0031792684 scopus 로고    scopus 로고
    • The smoothness index: A new, reproducible and officially relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension
    • Parati G, Omboni S, Rizzoni D, Agabiti-Rosei E, Mancia G.The smoothness index: a new, reproducible and officially relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension. J Hypertens 1998; 16:1685-1691.
    • (1998) J Hypertens , vol.16 , pp. 1685-1691
    • Parati, G.1    Omboni, S.2    Rizzoni, D.3    Agabiti-Rosei, E.4    Mancia, G.5
  • 35
    • 0031783720 scopus 로고    scopus 로고
    • The trough:peak ratio and the smoothness index in the evaluation of control of 24 h blood pressure by treatment in hypertension
    • Omboni S, Parati G, Mancia G. The trough:peak ratio and the smoothness index in the evaluation of control of 24 h blood pressure by treatment in hypertension. Blood Pressure Monit 1998; 3:201-204.
    • (1998) Blood Pressure Monit , vol.3 , pp. 201-204
    • Omboni, S.1    Parati, G.2    Mancia, G.3
  • 36
    • 0347385170 scopus 로고    scopus 로고
    • A randomized, double-blind, active-controlled, parallel-group comparison of valsartan and amlodipine in the treatment of isolated systolic hypertension in elderly patients: The Val-Syst study
    • Val-Syst study
    • Malacco E, Varì N, Capuano V, Spagnuolo V, Borgnino C, Palatini P, Val-Syst study. A randomized, double-blind, active-controlled, parallel-group comparison of valsartan and amlodipine in the treatment of isolated systolic hypertension in elderly patients: the Val-Syst study. Clin Ther 2003; 25:2765-2780.
    • (2003) Clin Ther , vol.25 , pp. 2765-2780
    • Malacco, E.1    Varì, N.2    Capuano, V.3    Spagnuolo, V.4    Borgnino, C.5    Palatini, P.6
  • 37
    • 0037945481 scopus 로고    scopus 로고
    • Comparison of the blood pressure-lowering effects and tolerability of Losartan-and Amlodipine-based regimens in patients with isolated sistoli hypertension
    • Volpe M, Junren Z, Maxwell T, Rodriguez A, Gamboa R, Gomez-Fernandez P, et al. Comparison of the blood pressure-lowering effects and tolerability of Losartan-and Amlodipine-based regimens in patients with isolated sistoli hypertension. Clin Ther 2003; 25:1469-1489.
    • (2003) Clin Ther , vol.25 , pp. 1469-1489
    • Volpe, M.1    Junren, Z.2    Maxwell, T.3    Rodriguez, A.4    Gamboa, R.5    Gomez-Fernandez, P.6
  • 38
    • 33750976110 scopus 로고    scopus 로고
    • Telmisartan plus HCTZ vs. amlodipine plus HCTZ in older patients with systolic hypertension: Results from a large ambulatory blood pressure monitoring study
    • ATHOS Study Group
    • Neldam S, Edwards C, ATHOS Study Group. Telmisartan plus HCTZ vs. amlodipine plus HCTZ in older patients with systolic hypertension: results from a large ambulatory blood pressure monitoring study. Am J Geriatr Cardiol 2006; 15:151-160.
    • (2006) Am J Geriatr Cardiol , vol.15 , pp. 151-160
    • Neldam, S.1    Edwards, C.2
  • 39
    • 0035071752 scopus 로고    scopus 로고
    • Antihypertensive treatment in elderly patients aged 75 years or over: A 24-week study of the tolerability of candesartan cilexetil in relation to hydrochlorothiazide
    • Multicentre Study Group
    • Neldam S, Forsén B, Multicentre Study Group. Antihypertensive treatment in elderly patients aged 75 years or over: a 24-week study of the tolerability of candesartan cilexetil in relation to hydrochlorothiazide. Drugs Aging 2001; 18:225-232.
    • (2001) Drugs Aging , vol.18 , pp. 225-232
    • Neldam, S.1    Forsén, B.2
  • 40
    • 34250370923 scopus 로고    scopus 로고
    • Antihypertensive activity of angiotensin II AT1 receptor antagonists: A systematic review of studies with 24 h ambulatory blood pressure monitoring
    • Fabia MJ, Abdilla N, Oltra R, Fernandez C, Redon J. Antihypertensive activity of angiotensin II AT1 receptor antagonists: a systematic review of studies with 24 h ambulatory blood pressure monitoring. J Hypertens 2007; 25:1327-1336.
    • (2007) J Hypertens , vol.25 , pp. 1327-1336
    • Fabia, M.J.1    Abdilla, N.2    Oltra, R.3    Fernandez, C.4    Redon, J.5
  • 41
    • 29244443966 scopus 로고    scopus 로고
    • Adding hydrochlorothiazide to olmesartan dose dependently improves 24-h blood pressure and response rates in mild-to-moderate hypertension
    • Sellin L, Stegbauer J, Laeis P, Rump LC. Adding hydrochlorothiazide to olmesartan dose dependently improves 24-h blood pressure and response rates in mild-to-moderate hypertension. J Hypertens 2005; 23:2083-2092.
    • (2005) J Hypertens , vol.23 , pp. 2083-2092
    • Sellin, L.1    Stegbauer, J.2    Laeis, P.3    Rump, L.C.4
  • 42
    • 12744269551 scopus 로고    scopus 로고
    • Use of 24-h ambulatory blood pressure monitoring to assess antihypertensive efficacy: A comparison of olmesartan medoxomil, losartan potassium, valsartan, and irbesartan
    • Smith DH, Dubiel R, Jones M. Use of 24-h ambulatory blood pressure monitoring to assess antihypertensive efficacy: a comparison of olmesartan medoxomil, losartan potassium, valsartan, and irbesartan. Am J Cardiovasc Drugs 2005; 5:41-50.
    • (2005) Am J Cardiovasc Drugs , vol.5 , pp. 41-50
    • Smith, D.H.1    Dubiel, R.2    Jones, M.3


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