Estimated average glucose and self-monitored mean blood glucose are discordant estimates of glycemic control

Diabetes Care

Volumn 33, Issue 7, 2010, Pages 1449-1451

  Hempe, James M ^a,b   Soros, Arlette A ^a   Chalew, Stuart A ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ARTICLE; BLOOD GLUCOSE MONITORING; CHILDHOOD DISEASE; CONTROLLED STUDY; DIABETIC PATIENT; DISEASE MARKER; GLUCOSE BLOOD LEVEL; GLYCATION; GLYCEMIC CONTROL; HEMOGLOBIN GLYCATION INDEX; HUMAN; IMMUNOASSAY; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MEAN BLOOD GLUCOSE; PEDIATRIC HOSPITAL; SELF MONITORING; BLOOD; CHILD; GLYCEMIC INDEX; HYPERGLYCEMIA; METABOLISM; RISK FACTOR; STATISTICAL MODEL;

BLOOD GLUCOSE; BLOOD GLUCOSE SELF-MONITORING; CHILD; DIABETES MELLITUS, TYPE 1; GLYCEMIC INDEX; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERGLYCEMIA; LINEAR MODELS; RISK FACTORS;

EID: 77958198932     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-1498     Document Type: Article

References (15)

1. Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ, A1c-Derived Average Glucose Study Group. Translating the A1C assay into estimated average glucose values. Diabetes Care 2008;31:1473-1478
2. Chalew S, Hempe JM. Caveats regarding the use of HbA1c for prediction of mean blood glucose. Diabetologia 2008;51:903-904
3. Kilpatrick ES, Rigby AS, Atkin SL. Variability in the relationship between mean plasma glucose and HbA1c: implications for the assessment of glycemic control. Clin Chem 2007;53:897-901
4. Bloomgarden ZT, Inzucchi SE, Karnieli E, Le Roith D. The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted. Diabetologia 2008;51:1111-1114
5. Nathan DM. Translating the A1C assay into estimated average glucose values: response to Rodriguez-Segade et al. and Leslie and Kilpatrick (Letter). Diabetes Care 2009;32:e12. DOI: 10.2337/dc08-1752
6. Rodriguez-Segade S, Rodriguez J, Paz JM, Camina F. Translating the A1C assay into estimated average glucose values: response to Nathan et al (Letter). Diabetes Care 2009;32:e10 DOI:10.2337/dc08-1214
7. Hempe JM, Gomez R, McCarter RJ Jr, Chalew SA. High and low hemoglobin glycation phenotypes in type 1 diabetes: a challenge for interpretation of glycemic control. J Diabetes Complications 2002;16:313-320
8. McCarter RJ, Hempe JM, Gomez R, Chalew SA. Biological variation in HbA1c predicts risk of retinopathy and nephropathy in type 1 diabetes. Diabetes Care 2004;27:1259-1264 (Pubitemid 38679967)
9. Cohen RM, Holmes YR, Chenier TC, Joiner CH. Discordance between HbA1c and fructosamine: evidence for a glycosylation gap and its relation to diabetic nephropathy. Diabetes Care 2003;26:163-167
10. The Diabetes Research in Children Network (DirecNet) Study Group. Relationship of A1c to glucose concentrations in children with type 1 diabetes: Assessments by high frequency glucose determinations by sensors. Diabetes Care 2008;31:381-385
11. Gould BJ, Davie SJ, Yudkin JS. Investigation of the mechanism underlying the variability of glycated haemoglobin in non-diabetic subjects not related to glycaemia. Clin Chim Acta 1997;260:49-64
12. Kilpatrick ES, Maylor PW, Keevil BG. Biological variation of glycated hemoglobin. Implications for diabetes screening and monitoring. Diabetes Care 1998;21:261-264
13. Rohlfing C, Wiedmeyer HM, Little R, Grotz VL, Tennill A, England J, Madsen R, Goldstein D. Biological variation of glycohemoglobin. Clin Chem 2002;48:1116-1118
14. Soros AA, Chalew SA, McCarter RJ, Shepard R, Hempe JM. Hemoglobin glycation index: a robust measure of hemoglobin A1c bias in pediatric type 1 diabetes patients. Pediatr Diabetes. 18 January 2010 [Epub ahead of print]
15. Little RR, Rohlfing CL, Wiedmeyer HM, Myers GL, Sacks DB, Goldstein DE, NGSP Steering Committee: The national glycohemoglobin standardization program: a five-year progress report. Clin Chem 2001;47:1985-1992