Recent developments in understanding dengue virus replication

Advances in Virus Research

Volumn 77, Issue C, 2010, Pages 1-39

  Urcuqui Inchima, Silvio ^a   Patiño, Claudia ^a   Torres, Silvia ^a   Haenni, Anne Lise ^a,b   Díaz, Francisco Javier ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b INSTITUT JACQUES MONOD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARBOVIRUS; BOOK; DENGUE; DENGUE VIRUS; DISEASE CARRIER; GENE EXPRESSION REGULATION; HUMAN; INCIDENCE; PATHOGENICITY; PHYSIOLOGY; VIROLOGY; VIRUS GENOME; VIRUS REPLICATION; SEVERE DENGUE;

ANIMALS; ARBOVIRUSES; DENGUE HEMORRHAGIC FEVER; DENGUE VIRUS; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HUMANS; INCIDENCE; INSECT VECTORS; VIRUS REPLICATION; SEVERE DENGUE;

EID: 77958195021     PISSN: 00653527     EISSN: 15578399     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385034-8.00001-6     Document Type: Book

References (200)

1. Ackermann M., Padmanabhan R. De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase. J. Biol. Chem. 2001, 276:39926-39937.
2. Acosta E.G., Castilla V., Damonte E.B. Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis. J. Gen. Virol. 2008, 89:474-484.
3. Alvarez D.E., Lodeiro M.F., Ludueña S.J., Pietrasanta L.I., Gamarnik A.V. Long-range RNA-RNA interactions circularize the dengue virus genome. J. Virol. 2005, 9:6631-6643.
4. Alvarez D.E., De Lella Ezcurra A.L., Fucito S., Gamarnik A.V. Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication. Virology 2005, 339:200-212.
5. Alvarez D.E., Filomatori C.V., Gamarnik A.V. Functional analysis of dengue virus cyclization sequences located at the 5' and 3'UTRs. Virology 2008, 375:223-235.
6. Ang F., Wong A., Ng M.M., Chu J.J. Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus. Virol. J. 2010, 7:24.
7. Ashour J., Laurent-Rolle M., Shi P.Y., García-Sastre A. NS5 of dengue virus mediates STAT2 binding and degradation. J. Virol. 2009, 83:5408-5418.
8. Barker W.C., Mazumder R., Vasudevan S., Sagripanti J.L., Wu C.H. Sequence signatures in envelope protein may determine whether flaviviruses produce hemorrhagic or encephalitic syndromes. Virus Genes 2009, 30:1-9.
9. Barnes W.J., Rosen L. Fatal hemorrhagic disease and shock associated with primary dengue infection on a Pacific island. Am. J. Trop. Med. Hyg. 1974, 23:495-506.
10. Bartenschlager R., Miller S. Molecular aspects of Dengue virus replication. Future Microbiol. 2008, 3:155-165.
11. Bera A.K., Kuhn R.J., Smith J.L. Functional characterization of cis and trans activity of the Flavivirus NS2B-NS3 protease. J. Biol. Chem. 2007, 282:12883-12892.
12. Bhuvanakantham R., Li J., Tan T.T., Ng M.L. Human Sec3 protein is a novel transcriptional and translational repressor of flavivirus. Cell. Microbiol. 2010, 12:453-472.
13. Boonnak K., Slike B.M., Burgess T.H., Mason R.M., Wu S.J., Sun P., Porter K., Rudiman I.F., Yuwono D., Puthavathana P., Marovich M.A. Role of dendritic cells in antibody-dependent enhancement of dengue virus infection. J. Virol. 2008, 82:3939-3951.
14. Bressanelli S., Stiasny K., Allison S.L., Stura E.A., Duquerroy S., Lescar J., Heinz F.X., Rey F.A. Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation. EMBO J. 2004, 23:728-738.
15. Brinton M.A., Dispoto J.H. Sequence and secondary structure analysis of the 5'-terminal region of flavivirus genome RNA. Virology 1988, 162:290-299.
16. Brinton M.A., Fernandez A.V., Dispoto J.H. The 3'-nucleotides of flavivirus genomic RNA form a conserved secondary structure. Virology 1986, 153:113-121.
17. Brooks A.J., Johansson M., John A.V., Xu Y., Jans D.A., Vasudevan S.G. The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals. J. Biol. Chem. 2002, 277:36399-36407.
18. Bryant J.E., Vasconcelos P.F., Rijnbrand R.C., Mutebi J.P., Higgs S., Barret A.D. Size heterogeneity in the 3' noncoding region of South American isolates of yellow fever virus. J. Virol. 2005, 79:3807-3821.
19. Bulich R., Aaskov J.G. Nuclear localization of dengue 2 virus core protein detected with monoclonal antibodies. J. Gen. Virol. 1992, 73:2999-3003.
20. Burke D.S., Nisalak A., Johnson D.E., Scott R.M. A prospective study of dengue infections in Bangkok. Am. J. Trop. Med. Hyg. 1988, 38:172-180.
21. Cabrera-Hernandez A., Thepparit C., Suksanpaisan L., Smith D.R. Dengue virus entry into liver (HepG2) cells is independent of hsp90 and hsp70. J. Med. Virol. 2007, 79:386-392.
22. Cahour A., Falgout B., Lai C.J. Cleavage of the dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular protease. J. Virol. 1992, 66:1535-1542.
23. Chang D.M., Shaio M.F. Production of interleukin-1 (IL-1) and IL-1 inhibitor by human monocytes exposed to dengue virus. J. Infect. Dis. 1994, 170:811-817.
24. Chavez-Salinas S., Ceballos-Olvera I., Reyes-Del Valle J., Medina F., Del Angel R.M. Heat shock effect upon dengue virus replication into U937 cells. Virus Res. 2008, 138:111-118.
25. Chen Y., Maguire T., Hileman R.E., Fromm J.R., Esko J.D., Linhardt R.J., Marks R.M. Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate. Nat. Med. 1997, 3:866-871.
26. Chen W., Gao N., Wang J.L., Tian Y.P., Chen Z.T., An J. Vimentin is required for dengue virus serotype 2 infection but microtubules are not necessary for this process. Arch. Virol. 2008, 153:1777-1781.
27. Chin J.F., Chu J.J., Ng M.L. The envelope glycoprotein domain III of dengue virus serotypes 1 and 2 inhibit virus entry. Microbes Infect. 2007, 9:1-6.
28. Chu J.J., Ng M.L. Infectious entry of West Nile virus occurs through a clathrin-mediated endocytic pathway. J. Virol. 2004, 78:10543-10555.
29. Chu J.J., Yang P.L. c-Src protein kinase inhibitors block assembly and maturation of dengue virus. Proc. Natl. Acad. Sci. USA 2007, 104:3520-3525.
30. Chu J.J., Leong P.W., Ng M.L. Analysis of the endocytic pathway mediating the infectious entry of mosquito-borne flavivirus West Nile into Aedes albopictus mosquito (C6/36) cells. Virology 2006, 349:463-475.
31. Clyde K., Harris E. RNA secondary structure in the coding region of dengue virus type 2 directs translation start codon selection and is required for viral replication. J. Virol. 2006, 80:2170-2182.
32. Clyde K., Kyle J.L., Harris E. Recent advances in deciphering viral and host determinants of dengue virus replication and pathogenesis. J. Virol. 2006, 80:11418-11431.
33. Cologna R., Rico-Hesse R. American genotype structures decrease dengue virus output from human monocytes and dendritic cells. J. Virol. 2003, 77:3929-3938.
34. Colombo M.I. Pathogens and autophagy: Subverting to survive. Cell Death Differ. 2005, 12:1481-1483.
35. Davidson A.D. Chapter 2. New insights into flavivirus nonstructural protein 5. Adv. Virus Res. 2009, 74:41-101.
36. Davis W.G., Blackwell J.L., Shi P.Y., Brinton M.A. Interaction between the cellular protein eEF1A and the 3'-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis. J. Virol. 2007, 81:10172-10187.
37. De Nova-Ocampo M., Villegas-Sepúlveda N., del Angel R.M. Translation elongation factor-1alpha, La, and PTB interact with the 3' untranslated region of dengue 4 virus RNA. Virology 2002, 295:337-347.
38. Dejnirattisai W., Jumnainsong A., Onsirisakul N., Fitton P., Vasanawathana S., Limpitikul W., Puttikhunt C., Edwards C., Duangchinda T., Supasa S., Chawansuntati K., Malasit P., et al. Cross-reacting antibodies enhance dengue virus infection in humans. Science 2010, 328:745-748.
39. Diaz F.J., Black W.C., Farfan-Ale J.A., Loroño-Pino M.A., Olson K.E., Beaty B.J. Dengue virus circulation and evolution in Mexico: A phylogenetic perspective. Arch. Med. Res. 2006, 37:760-773.
40. Döhner K., Sodeik B. The role of the cytoskeleton during viral infection. Curr. Top. Microbiol. Immunol. 2005, 285:67-108.
41. Duan X., Lu X., Li J., Liu Y. Novel binding between pre-membrane protein and vacuolar ATPase is required for efficient dengue virus secretion. Biochem. Biophys. Res. Commun. 2008, 373:319-324.
42. Dunn W.A. Studies on the mechanisms of autophagy: Formation of the autophagic vacuole. J. Cell Biol. 1990, 110:1923-1933.
43. Edgil D., Diamond M.S., Holden K.L., Paranjape S.M., Harris E. Translation efficiency determines differences in cellular infection among dengue virus type 2 strains. Virology 2003, 317:275-290.
44. Edgil D., Polacek C., Harris E. Dengue virus utilizes a novel strategy for translation initiation when cap-dependent translation is inhibited. J. Virol. 2006, 80:2976-2986.
45. Egloff M.P., Benarroch D., Selisko B., Romette J.L., Canard B. An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: Crystal structure and functional characterization. EMBO J. 2002, 21:2757-2768.
46. Egloff M.P., Decroly E., Malet H., Selisko B., Benarroch D., Ferron F., Canard B. Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of Dengue virus NS5. J. Mol. Biol. 2007, 372:723-736.
47. Elshuber S., Allison S.L., Heinz F.X., Mandl C.W. Cleavage of protein prM is necessary for infection of BHK-21 cells by Tick-borne encephalitis virus. J. Gen. Virol. 2003, 84:183-191.
48. Falconar A.K. The dengue virus nonstructural-1 protein (NS1) generates antibodies to common epitopes on human blood clotting, integrin/adhesin proteins and binds to human endothelial cells: Potential implications in haemorrhagic fever pathogenesis. Arch. Virol. 1997, 142:897-916.
49. Falgout B., Pethel M., Zhang Y.M., Lai C.J. Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins. J. Virol. 1991, 65:2467-2475.
50. Filomatori C.V., Lodeiro M.F., Alvarez D.E., Samsa M.M., Pietrasanta L., Gamarnik A.V. A 5' RNA element promotes dengue virus RNA synthesis on a circular genome. Genes Dev. 2006, 20:2238-2249.
51. Friebe P., Harris E. Interplay of RNA elements in the Dengue virus 5' and 3' ends required for viral RNA replication. J. Virol. 2010, 84:6103-6118.
52. Furuichi Y., Shatkin A.J. Viral and cellular mRNA capping: Past and prospects. Adv. Virus Res. 2000, 55:135-184.
53. Gagnon S.J., Mori M., Kurane I., Green S., Vaughn D.W., Kalayanarooj S., Suntayakorn S., Ennis F.A., Rothman A.L. Cytokine gene expression and protein production in peripheral blood mononuclear cells of children with acute dengue virus infections. J. Med. Virol. 2002, 67:41-46.
54. Gao F., Duan X., Lu X., Liu Y., Zheng L., Ding Z., Li J. Novel binding between pre-membrane protein and claudin-1 is required for efficient dengue virus entry. Biochem. Biophys. Res. Commun. 2010, 391:952-957.
55. Garcia-Montalvo B.M., Medina F., del Angel R.M. La protein binds to NS5 and NS3 and to the 5' and 3' ends of Dengue 4 virus RNA. Virus Res. 2004, 102:141-150.
56. Geiss B.J., Thompson A.A., Andrews A.J., Sons R.L., Gari H.H., Keenan S.M., Peersen O.B. Analysis of flavivirus NS5 methlytransferase cap binding. J. Mol. Biol. 2009, 385:1643-1654.
57. Germi R., Crance J.M., Garin D., Guimet J., Lortat-Jacob L., Ruigrok R.W.H., Zarski J.P., Drouet E. Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus. Virology 2002, 292:162-168.
58. Grange T., Bouloy M., Girard M. Stable secondary structures at the 3'-end of the genome of yellow fever virus (17 D vaccine strain). FEBS Lett. 1985, 188:159-163.
59. Green S., Rothman A. Immunopathological mechanisms in dengue and dengue hemorrhagic fever. Curr. Opin. Infect. Dis. 2006, 19:429-436.
60. Gubler D.J. Dengue and dengue haemorrhagic fever. Clin. Microbiol. Rev. 1998, 11:480-496.
61. Gubler D.J., Clark G.G. Dengue/dengue hemorrhagic fever: The emergence of a global health problem. Emerg. Infect. Dis. 1995, 1:55-57.
62. Gubler D.J., Reed D., Rosen L., Hitchcock J.R. Epidemiologic, clinical and virologic observations on dengue in the Kingdom of Tonga. Am. J. Trop. Med. Hyg. 1978, 27:581-589.
63. Gubler D., Kuno G., Markoff L. Flaviviruses. Field's Virology 2007, 1153-1252. Lippincott-Raven Publishers, Philadelphia. 5th Edn. D.M. Knipe, P.M. Howley (Eds.).
64. Guha-Sapir D., Schimmer B. Dengue fever: New paradigms for a changing epidemiology. Emerg. Themes Epidemiol. 2005, 2:1.
65. Guirakhoo F., Hunt A.R., Lewis J.G., Roehrig J.T. Selection and partial characterization of dengue 2 virus mutants that induce fusion at elevated pH. Virology 1993, 194:219-223.
66. Guzman M.G., Kouri G. Dengue: An update. Lancet Infect. Dis. 2002, 2:33-42.
67. Hahn C.S., Hahn Y.S., Rice C.M., Lee E., Dalgarno L., Strauss E.G., Strauss J.H. Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences. J. Mol. Biol. 1987, 198:33-41.
68. Halstead S.B. The Alexander D. Langmuir Lecture. The pathogenesis of dengue. Molecular epidemiology in infectious disease. Am. J. Epidemiol. 1981, 114:632-648.
69. Halstead S.B. Pathogenesis of dengue: Challenges to molecular biology. Science 1988, 239:476-481.
70. Halstead S.B., O'Rourke E.J. Antibody-enhanced dengue virus infection in primate leukocytes. Nature 1977, 265:739-741.
71. Halstead S.B., O'Rourke E.J., Allison A.C. Dengue viruses and mononuclear phagocytes. II. Identity of blood and tissue leukocytes supporting in vitro infection. J. Exp. Med. 1977, 146:218-229.
72. Hanna S.L., Pierson T.C., Sanchez M.D., Ahmed A.A., Murtadha M.M., Doms R.W. N-linked glycosylation of West Nile virus envelope proteins influences particle assembly and infectivity. J. Virol. 2005, 79:13262-13274.
73. Harris E., Holden K.L., Edgil D., Polacek C., Clyde K. Molecular biology of flaviviruses. Novartis Found. Symp. 2006, 277:23-39.
74. Hase T., Summers P.L., Cohen W.H. A comparative study of entry modes into C6/36 cells by Semliki Forest and Japanese encephalitis viruses. Arch. Virol. 1989, 108:101-114.
75. Hase T., Summers P.L., Eckels K.H. Flavivirus entry into cultured mosquito cells and human peripheral blood monocytes. Arch. Virol. 1989, 104:129-143.
76. Heinz F.X., Allison S.L. Flavivirus structure and membrane fusion. Adv. Virus Res. 2003, 59:63-97.
77. Heinz F.X., Stiasny K., Allison S.L. The entry machinery of flaviviruses. Arch. Virol. Suppl. 2004, 18:133-137.
78. Hershkovitz O., Rosental B., Rosenberg L.A., Navarro-Sanchez M.E., Jivov S., Zilka A., Gershoni-Yahalom O., Brient-Litzler E., Bedouelle H., Ho J.W., Campbell K.S., Rager-Zisman B., et al. NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells. J. Immunol. 2009, 183:2610-2621.
79. Hober D., Poli L., Roblin B., Gestas P., Chungue E., Granic G., Imbert P., Pecarere J.L., Vergez-Pascal R., Wattre P., Maniez-Montreuil M. Serum levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1 beta (IL-1 beta) in dengue-infected patients. Am. J. Trop. Med. Hyg. 1993, 48:324-331.
80. Holden K.L., Harris E. Enhancement of dengue virus translation: Role of the 3' untranslated region and the terminal 3' stem-loop domain. Virology 2004, 329:119-133.
81. Hsieh S.C., Tsai W.Y., Wang W.K. The length of and nonhydrophobic residues in the transmembrane domain of dengue virus envelope protein are critical for its retention and assembly in the endoplasmic reticulum. J. Virol. 2010, 84:4782-4797.
82. Huerta V., Chinea G., Fleitas N., Sarria M., Sanchez J., Toledo P., Padron G. Chacterization of the interaction of domain III of the envelope protein of dengue virus with putative receptors from CHO cells. Virus Res. 2008, 137:225-234.
83. Jones M., Davidson A., Hibbert L., Gruenwald P., Schlaak J., Ball S., Foster G.R., Jacobs M. Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression. J. Virol. 2005, 79:5414-5420.
84. Kanlaya R., Pattanakitsakul S.N., Sinchaikul S., Chen S.T., Thongboonkerd V. Alterations in actin cytoskeletal assembly and junctional protein complexes in human endothelial cells induced by dengue virus infection and mimicry of leukocyte transendothelial migration. J. Proteome Res. 2009, 8:2551-2562.
85. Kapoor M., Zhang L., Ramachandra M., Kusukawa J., Ebner K.E., Padmanabhan R. Association between NS3 andNS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5. J. Biol. Chem. 1995, 270:19100-19116.
86. Khakpoor A., Panyasrivanit M., Wikan N., Smith D.R. A role for autophagolysosomes in dengue virus 3 production in HepG2 cells. J. Gen. Virol. 2009, 90:1093-1103.
87. Khromykh A.A., Sedlak P.L., Westaway E.G. trans-Complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replication. J. Virol. 1999, 73:9247-9255.
88. Khromykh A.A., Meka H., Guyatt K.J., Westaway E.G. Essential role of cyclization sequences in Flavivirus RNA replication. J. Virol. 2001, 75:6719-6728.
89. Kiermayr S., Kofler R.M., Mandl C.W., Messner P., Heinz F.X. Isolation of capsid protein dimers from the tick-borne encephalitis flavivirus and in vitro assembly of capsid-like particles. J. Virol. 2004, 78:8078-8084.
90. King A.D., Nisalak A., Kalayanrooj S., Myint K.S., Pattanapanyasat K., Nimmannitya S., Innis B.L. B cells are the principal circulating mononuclear cells infected by dengue virus. Southeast Asian J. Trop. Med. Public Health 1999, 30:718-728.
91. Kliks S.C., Nisalak A., Brandt W.E., Wahl L., Burke D.S. Antibody-dependent enhancement of dengue virus growth in human monocytes as a risk factor for dengue hemorrhagic fever. Am. J. Trop. Med. Hyg. 1989, 40:444-451.
92. Konishi E., Mason P.W. Proper maturation of the Japanese encephalitis virus envelope glycoprotein requires cosynthesis with the premembrane protein. J. Virol. 1993, 67:1672-1675.
93. Kou Z., Quinn M., Chen H., Rodrigo W.W., Rose R.C., Schlessinger J.J., Jin X. Monocytes but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells. J. Med. Virol. 2008, 80:134-146.
94. Krishnan M.N., Sukumaran B., Pal U., Agaisse H., Murray J.L., Hodge T.W., Fikrig E. Rab 5 is required for the cellular entry of Dengue and West Nile viruses. J. Virol. 2007, 81:4881-4885.
95. Kuma A., Hatano M., Matsui M., Yamamoto A., Nakaya H., Yoshimori T., Ohsumi Y., Tokuhisa T., Mizushima N. The role of autophagy during the early neonatal starvation period. Nature 2004, 432:1032-1036.
96. Kümmerer B.M., Rice C.M. Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles. J. Virol. 2002, 76:4773-4784.
97. Lee C.J., Lin H.R., Liao C.L., Lin Y.L. Cholesterol effectively blocks entry of flavivirus. J. Virol. 2008, 82:6470-6480.
98. Lee Y.R., Lei H.Y., Liu M.T., Wang J.R., Chen S.H., Jiang-Shieh Y.F., Lin Y.S., Yeh T.M., Liu C.C., Liu H.S. Autophagic machinery activated by dengue virus enhances virus replication. Virology 2008, 374:240-248.
99. Lee E., Leang S.K., Davidson A., Lobigs M. Both E protein glycans adversely affect dengue virus infectivity but are beneficial for virion release. J. Virol. 2010, 84:5171-5180.
100. Leitmeyer K.C., Vaughn D.W., Watts D.M., Salas R., Villalobos I.de chacon, Ramos C., Rico-Hesse R. Dengue virus structural differences that correlate with pathogenesis. J. Virol. 1999, 73:4738-4747.
101. Leung D., Schroder K., White H., Fang N.X., Stoermer M.J., Abbenante G., Martin J.L., Young P.R., Fairlie D.P. Activity of dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. J. Biol. Chem. 2001, 276:45762-45771.
102. Li H., Clum S., You S., Ebner K.E., Padmanabhan R. The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase fuctional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. J. Virol. 1999, 73:3108-3116.
103. Li L., Lok S.M., Yu I.M., Zhang Y., Kuhn R.J., Chen J., Rossmann M.G. The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science 2008, 319:1830-1834.
104. Lim H.Y., Ng M.L. A different mode of entry by dengue-2 neutralisation escape mutant virus. Arch. Virol. 1999, 144:989-995.
105. Limjindaporn T., Wongwiwat W., Noisakran S., Srisawat C., Netsawang J., Puttikhunt C., Kasinrerk W., Avirutnan P., Thiemmeca S., Sriburi R., Sittisombut N., Malasit P., et al. Interaction of dengue virus envelope protein with endoplasmic reticulum-resident chaperones facilitates dengue virus production. Biochem. Biophys. Res. Commun. 2009, 379:196-200.
106. Lin Y.L., Lei H.Y., Lin Y.S., Yeh T.M., Chen S.H., Liu H.S. Heparin inhibits dengue-2 virus infection of five human liver cell lines. Antiviral Res. 2002, 56:93-96.
107. Lin T.W., Lo C.W., Lai S.Y., Fan R.J., Lo C.J., Chou Y.M., Thiruvengadam R., Wang A.H.J., Wang M.Y. Chicken heat shock protein 90 is a component of the putative cellular receptor complex of infectious bursal disease virus. J. Virol. 2007, 81:8730-8741.
108. Lindenbach B.D., Rice C.M. trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication. J. Virol. 1997, 71:9608-9617.
109. Lindenbach B.D., Rice C.M. Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J. Virol. 1999, 73:4611-4621.
110. Lindenbach B.D., Rice C.M. Molecular biology of flaviviruses. Adv. Virus Res. 2003, 59:23-61.
111. Liu R., Yue L., Li X., Yu X., Zhao H., Jiang Z., Qin E., Qin C. Identification and characterization of small sub-genomic RNAs in dengue 1-4 virus-infected cell cultures and tissues. Biochem. Biophys. Res. Commun. 2010, 391:1099-1103.
112. Lo M.K., Tilgner M., Bernard K.A., Shi P.Y. Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3'untranslated region of West Nile virus by use of a reporting replicon that differentiates viral translation and RNA replication. J. Virol. 2003, 77:1004-1014.
113. Lodeiro M.F., Filomatori C.V., Gamarnik A.V. Structural and functional studies of the promoter element for dengue virus RNA replication. J. Virol. 2009, 83:993-1008.
114. Lopez C., Gil L., Lazo L., Menéndez I., Marcos E., Sanchez J., Valdes I., Falcon V., de la Rosa M.C., Marquez G., Guillen G., Hermida L. In vitro ssembly of nucleocapsid-like particles from purified recombinant capsid protein of dengue-2 virus. Arch. Virol. 2009, 154:695-698.
115. Lozach P.Y., Burleigh L., Staropoli I., Navarro-Sanchez E., Harriague J., Virelizier J.L., Rey F.A., Desprès P., Arenzana-Seisdedos F., Amara A. Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals. J. Biol. Chem. 2005, 280:23698-23708.
116. Luo D., Xu T., Hunke C., Grüber G., Vasudevan S.G., Lescar J. Crystal structure of the NS3 protease-helicase from dengue virus. J. Virol. 2008, 82:173-183.
117. Luo D., Xu T., Watson R.P., Scherer-Becker D., Sampath A., Jahnke W., Yeong S.S., Wang C.H., Lim S.P., Strongin A., Vasudevan S.G., Lescar J. Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein. EMBO J. 2008, 27:3209-3219.
118. Ma L., Jones C.T., Groesch T.D., Kuhn R.J., Post C.B. Solution structure of dengue virus capsid protein reveals another fold. Proc. Natl. Acad. Sci. USA 2004, 101:3414-3419.
119. Mackenzie J.M., Khromykh A.A., Jones M.K., Westaway E.G. Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A. Virology 1998, 245:203-215.
120. Markoff L. 5'- and 3'-noncoding regions in flavivirus RNA. Adv. Virus Res. 2003, 59:177-228.
121. Markoff L., Falgout B., Chang A. A conserved internal hydrophobic domain mediates the stable membrane integration of the dengue virus capsid protein. Virology 1997, 233:105-117.
122. Marovich M., Grouard-Vogel G., Louder M., Eller M., Sun W., Wu S.J., Putvatana R., Murphy G., Tassaneetrithep B., Burgess T., Birx D., Hayes C., et al. Human dendritic cells as targets of dengue virus infection. J. Investig. Dermatol. Symp. Proc. 2001, 6:219-224.
123. Mathew A., Rothman A.L. Understanding the contribution of cellular immunity to dengue disease pathogenesis. Immunol. Rev. 2008, 225:300-313.
124. Mazzon M., Jones M., Davidson A., Chain B., Jacobs M. Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation. J. Infect. Dis. 2009, 2009:1261-1270.
125. Medeiros D.B., Nunes M.R., Vasconcelos P.F., Chang G.J., Kuno G. Complete genome characterization of Rocio virus (Flavivirus: Flaviviridae), a Brazilian flavivirus isolated from a fatal case of encephalitis during an epidemic in Sao Paulo state. J. Gen. Virol. 2007, 88:2237-2246.
126. Men R., Bray M., Clark D., Chanock R.M., Lai C.J. Dengue type 4 virus mutants containing deletions in the 3' noncoding region of the RNA genome: Analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys. J. Virol. 1996, 70:3930-3937.
127. Miller S., Krijnse-Locker J. Modification of intracellular membrane structures for virus replication. Nat. Rev. Microbiol. 2008, 6:363-374.
128. Miller S., Sparacio S., Bartenschlager R. Subcellular localization and membrane topology of the Dengue virus type 2 non-structural protein 4B. J. Biol. Chem. 2006, 281:8854-8863.
129. Miller S., Kastner S., Krijnse-Locker J., Bühler S., Bartenschlager R. The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner. J. Biol. Chem. 2007, 282:8873-8882.
130. Mohan P.M., Padmanabhan R. Detection of stable secondary structure at the 3' terminus of dengue virus type 2 RNA. Gene 1991, 108:185-191.
131. Moi M.L., Lim C.K., Takasaki T., Kurane I. Involvement of the Fc gamma receptor IIA cytoplasmic domain in antibody-dependent enhancement of dengue virus infection. J. Gen. Virol. 2010, 91:103-111.
132. Morens D.M., Sather G.E., Gubler D.J., Rammohan M., Woodall J.P. Dengue shock syndrome in an American traveler with primary dengue 3 infection. Am. J. Trop. Med. Hyg. 1987, 36:424-426.
133. Mukherjee S., Hanley K.A. RNA interference modulates replication of dengue virus in Drosophila melanogaster cells. BMC Microbiol. 2010, 10:127.
134. Mukhopadhyay S., Kuhn R.J., Rossmann M.G. A structural perspective of the flavivirus life cycle. Nat. Rev. Microbiol. 2005, 3:13-22.
135. Munoz-Jordan J.L., Sanchez-Burgos G.G., Laurent-Rolle M., Garcia-Sastre A. Inhibition of interferon signaling by dengue virus. Proc. Natl. Acad. Sci. USA 2003, 100:14333-14338.
136. Muylaert I.R., Galler R., Rice C.M. Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation. J. Virol. 1997, 71:291-298.
137. Netsawang J., Noisakran S., Puttikhunt C., Kasinrerk W., Wongwiwat W., Malasit P., Yenchitsomanus P.T., Limjindaporn T. Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis. Virus Res. 2010, 147:275-283.
138. Nomaguchi M., Teramoto T., Yu L., Markoff L., Padmanabhan R. Requirements for West Nile virus (-)- and (+)-strand subgenomic RNA synthesis in vitro by the viral RNA-dependent RNA polymerase expressed in Escherichia coli. J. Biol. Chem. 2004, 279:12141-12151.
139. Panyasrivanit M., Khakpoor A., Wikan N., Smith D.R. Linking dengue virus entry and translation/replication through amphisomes. Autophagy 2009, 5:434-435.
140. Panyasrivanit M., Khakpoor A., Wikan N., Smith D.R. Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes. J. Gen. Virol. 2009, 90:448-456.
141. Paranjape S.M., Harris E. Y box-binding protein-1 binds to the dengue virus 3'-untranslated region and mediates antiviral effects. J. Biol. Chem. 2007, 282:30497-30508.
142. Perara R., Khaliq M., Kuhn R.J. Closing the door on flaviviruses: Entry as a target for antiviral drug design. Antiviral Res. 2008, 80:11-22.
143. Perera R., Kuhn R.J. Structural proteomics of dengue virus. Curr. Opin. Microbiol. 2008, 11:366-377.
144. Pierson T.C., Diamond M.S. Molecular mechanisms of antibody-mediated neutralisation of flavivirus infection. Expert Rev. Mol. Med. 2008, 10:e12.
145. Pijlman G.P., Funk A., Kondratieva N., Leung J., Torres S., van der Aa L., Liu W.J., Palmenberg A.C., Shi P.Y., Hall R.A., Khromykh A.A. A highly structured, nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity. Cell Host Microbe 2008, 4:579-591.
146. Polacek C., Foley J.E., Harris E. Conformational changes in the solution structure of the dengue virus 5' end in the presence and absence of the 3' untranslated region. J. Virol. 2009, 83:1161-1166.
147. Polacek C., Friebe P., Harris E. Poly(A)-binding protein binds to the non-polyadenylated 3' untranslated region of dengue virus and modulates translation efficiency. J. Gen. Virol. 2009, 90:687-692.
148. Pryor M.J., Azzola L., Wright P.J., Davidson A.D. Histidine 39 in the dengue virus type 2M protein has an important role in virus assembly. J. Gen. Virol. 2004, 85:3627-3636.
149. Puerta-Guardo H., Mosso C., Medina F., Liprandi F., Ludert J.E., del Angel R.M. Antibody-dependent enhancement of dengue virus infection in U937 cells requires cholesterol-rich membrane microdomains. J. Gen. Virol. 2010, 91:394-403.
150. Rawlinson S.M., Pryor M.J., Wright P.J., Jans D.A. CRM1-mediated nuclear export of dengue virus RNA polymerase NS5 modulates interleukin-8 induction and virus production. J. Biol. Chem. 2009, 284:15589-15597.
151. Ren J., Ding T., Zhang W., Song J., Ma W. Does Japanese encephalitis virus share the same cellular receptor with other mosquito-borne flaviviruses on the C6/36 mosquito cells?. Virol. J. 2007, 4:83.
152. Reyes-del Valle J., Chavez-Salinas S., Medina F., del Angel R.M. Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells. J. Virol. 2005, 79:4557-4567.
153. Rico-Hesse R. Dengue virus virulence and transmission determinants. Curr. Top. Microbiol. Immunol. 2010, 338:45-55.
154. Rodrigo W.W., Jin X., Blackley S.D., Rose R.C., Schlesinger J.J. Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human FcγRIA (CD64) or FcγRIIA (CD32). J. Virol. 2006, 80:10128-10138.
155. Rothwell C., Lebreton A., Young Ng C., Lim J.Y., Liu W., Vasudevan S., Labow M., Gu F., Gaither L.A. Cholesterol biosynthesis modulation regulates dengue viral replication. Virology 2009, 389:8-19.
156. Sampath A., Xu T., Chao A., Luo D., Lescar J., Vasudevan S.G. Structure-based mutational analysis of the NS3 helicase from dengue virus. J. Virol. 2006, 80:6686-6690.
157. Samsa M.M., Mondotte J.A., Iglesias N.G., Assunção-Miranda I., Barbosa-Lima G., Da Poian A.T., Bozza P.T., Gamarnik A.V. Dengue virus capsid protein usurps lipid droplets for viral particle formation. PLoS Pathog. 2009, 5:e1000632.
158. Sánchez-Vargas I., Scott J.C., Poole-Smith B.K., Franz A.W.E., Barbosa-Solomieu V., Wilusz J., Olson K.E., Blair C.D. Dengue virus type 2 infections of Aedes aegypti are modulated by the mosquito's RNA interference pathway. PLoS Pathog. 2009, 5:e1000299.
159. Sangiambut S., Keelapang P., Aaskov J., Puttikhunt C., Kasinrerk W., Malasit P., Sittisombut N. Multiple regions in dengue virus capsid protein contribute to nuclear localization during virus infection. J. Gen. Virol. 2008, 89:1254-1264.
160. Sangkawibha N., Rojanasuphot S., Ahandrik S., Viriyapongse S., Jatanasen S., Salitul V., Phanthumachinda B., Halstead S.B. Risk factors in dengue shock syndrome: A prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak. Am. J. Epidemiol. 1984, 120:653-669.
161. Selisko B., Peyrane F.F., Canard B., Alvarez K., Decroly E. Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides (7Me)GpppAC(n) and GpppAC(n). J. Gen. Virol. 2010, 91:112-121.
162. Se-Thoe S.Y., Ling A.E., Ng M.M. Alteration of virus entry mode: A neutralisation mechanism for Dengue-2 virus. J. Med. Virol. 2000, 62:364-376.
163. Subramanya S., Kim S.S., Abraham S., Yao J., Kumar M., Kumar P., Haridas V., Lee S.K., Shultz L.D., Greiner D., Manjunath N., Shankar P. Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production. J. Virol. 2010, 84:2490-2501.
164. Suksanpaisan L., Susantad T., Smit D.R. Characterization of dengue virus entry into HepG2 cells. J. Biomed. Sci. 2009, 16:17.
165. Tadano M., Makino Y., Fukunaga T., Okuno Y., Fukai K. Detection of dengue 4 virus core protein in the nucleus. I. A monoclonal antibody to dengue 4 virus reacts with the antigen in the nucleus and cytoplasm. J. Gen. Virol. 1989, 70:1409-1415.
166. Talavera D., Castillo A.M., Dominguez M.C., Gutierrez A.E., Meza I. IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers. J. Gen. Virol. 2004, 85:1801-1813.
167. Tassaneetrithep B., Burgess T.H., Granelli-Piperno A., Trumpfheller C., Finke J., Sun W., Eller M.A., Pattanapanyasat K., Sarasombath S., Birx D.L., Steinman R.M., Schlesinger S., et al. DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J. Exp. Med. 2003, 197:823-829.
168. Trung D.T., Wills B. Systemic vascular leakage associated with dengue infections - the clinical perspective. Curr. Top. Microbiol. Immunol. 2010, 338:57-66.
169. Tsuda Y., Mori Y., Abe T., Yamashita T., Okamoto T., Ichimura T., Moriishi K., Matsuura Y. Nucleolar protein B23 interacts with Japanese encephalitis virus core protein and participates in viral replication. Microbiol. Immunol. 2006, 50:225-234.
170. Uchil P.D., Satchidanandam V. Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments. J. Biol. Chem. 2003, 278:24388-24398.
171. Uchil P.D., Kumar A.V., Satchidanandam V. Nuclear localization of flavivirus RNA synthesis in infected cells. J. Virol. 2006, 80:5451-5464.
172. Umareddy I., Chao A., Sampath A., Gu F., Vasudevan S.G. Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA. J. Gen. Virol. 2006, 87:2605-2614.
173. Upanan S., Kuadkitkan A., Smith D.R. Identification of dengue virus binding proteins using affinity chromatography. J. Virol. Meth. 2008, 151:325-328.
174. Van der Schaar H., Rust M.J., Chen C., van der Ende-Metselaar H., Wilschut J., Zhuang X., Smit J.M. Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells. PLoS Pathog. 2008, 4(e1000244):1-9.
175. Vaughn D.W., Green S., Kalayanarooj S., Innis B.L., Nimmannitya S., Suntayakorn S., Rothman A.L., Ennis F.A., Nisalak A. Dengue in the early febrile phase: Viremia and antibody responses. J. Infect. Dis. 1997, 176:322-330.
176. Wallner G., Mandl C.W., Kunz C., Heinz F.X. The flavivirus 3'-noncoding region: Extensive size heterogeneity independent of evolutionary relationships among strains of tick-borne encephalitis virus. Virology 1995, 213:169-178.
177. Wang S.H., Syu W.J., Huang K.J., Lei H.Y., Yao C.W., King C.C., Hu S.T. Intracellular localization and determination of a nuclear localization signal of the core protein of dengue virus. J. Gen. Virol. 2002, 83:3093-3102.
178. Wang C.C., Huang Z.S., Chiang P.L., Chen C.T., Wu H.N. Analysis of the nucleoside triphosphatase, RNA triphosphatase, and unwinding activities of the helicase domain of dengue virus NS3 protein. FEBS Lett. 2009, 583:691-696.
179. Wang P.G., Kudelko M., Lo J., Siu L.Y., Kwok K.T., Sachse M., Nicholls J.M., Bruzzone R., Altmeyer R.M., Nal B. Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. PLoS ONE 2009, 4:e8325.
180. Watts D.M., Porter K.R., Putvatana P., Vasquez B., Calampa C., Hayes C.G., Halstead S.B. Failure of secondary infection with American genotype dengue 2 to cause dengue haemorrhagic fever. Lancet 1999, 354:1431-1434.
181. Wengler G., Wengler G. Cell-associated West Nile flavivirus is covered with E+pre-M protein heterodimers which are destroyed and reorganized by proteolytic cleavage during virus release. J. Virol. 1989, 63:2521-2526.
182. Wengler G., Wengler G. The NS 3 nonstructural protein of flaviviruses contains an RNA triphosphatase activity. Virology 1993, 197:265-273.
183. Westaway E.G., Mackenzie J.M., Kenney M.T., Jones M.K., Khromykh A.A. Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures. J Virol. 2010, 71:6650-6661.
184. Wilder-Smith A., Gubler D.J. Geographic expansion of dengue: The impact of international travel. Med. Clin. N. Am. 2008, 92:1377-1390.
185. World Health Organization (WHO) Dengue: Guidelines for diagnosis, treatment, prevention and control 2009, WHO press, Geneva, Switzerland.
186. Wu S.J., Grouard-Vogel G., Sun W., Mascola J.R., Brachtel E., Putvatana R., Louder M.K., Filgueira L., Marovich M.A., Wong H.K., Blauvelt A., Murphy G.S., et al. Human skin Langerhans cells are targets of dengue virus infection. Nat. Med. 2000, 6:816-820.
187. Yap T.L., Xu T., Chen Y.L., Malet H., Egloff M.P., Canard B., Vasudevan S.G., Lescar J. Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution. J. Virol. 2007, 81:4753-4765.
188. Yocupicio-Monroy R.M., Medina F., Reyes-del Valle J., del Angel R.M. Cellular proteins from human monocytes bind to dengue 4 virus minus-strand 3' untranslated region RNA. J. Virol. 2003, 77:3067-3076.
189. Yon C., Teramoto T., Mueller N., Phelan J., Ganesh V.K., Murthy K.H., Padmanabhan R. Modulation of the nucleoside triphosphatase/RNA helicase and 5'-RNA triphosphatase activities of Dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase. J. Biol. Chem. 2005, 280:27412-27419.
190. You S., Falgout B., Markoff L., Padmanabhan R. In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5'- and 3'-terminal regions that influence RNA structure. J. Biol. Chem. 2001, 276:15581-15591.
191. Yu I.M., Zhang W., Holdaway H.A., Li L., Kostyuchenko V.A., Chipman P.R., Kuhn R.J., Rossmann M.G., Chen J. Stucture of the immature Dengue virus at low pH primes proteolytic maturation. Science 2008, 319:1834-1837.
192. Yu L., Nomaguchi M., Padmanabhan R., Markoff L. Specific requirements for elements of the 5' and 3' terminal regions in flavivirus RNA synthesis and viral replication. Virology 2008, 374:170-185.
193. Yu I.M., Holdaway H.A., Chipman P.R., Kuhn R.J., Rossmann M.G., Chen J. Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion. J. Virol. 2009, 83:12101-12107.
194. Zamudio-Meza H., Castillo-Alvarez A., González-Bonilla C., Meza I. Cross-talk between Rac1 and Cdc42 GTPases regulates formation of filopodia required for dengue virus type-2 entry into HMEC-1 cells. J. Gen. Virol. 2009, 90:2902-2911.
195. Zhang Y., Corver J., Chipman P.R., Zhang W., Pletnev S.V., Dagmar S., Baker T.S., Strauss J.H., Kuhn R.J., Rossmann M.G. Structures of immature flavivirus particles. EMBO J. 2003, 22:2604-2613.
196. Zhang W., Singam R., Hellermann G., Kong X., Juan H.S., Lockey R.F., Wu S.J., Porter K., Mohapatra S.S. Attenuation of dengue virus infection by adeno-associated virus-mediated siRNA delivery. Genet. Vaccines Ther. 2004, 2:8.
197. Zhang J.L., Wang J.L., Gao N., Chen Z.T., Tian Y.P., An J. Up-regulated expression of beta3 integrin induced by dengue virus serotype 2 infection associated with virus entry into human dermal microvascular endothelial cells. Biochem. Biophys. Res. Commun. 2007, 356:763-768.
198. Zheng Z.Z., Miao J., Zhao M., Tang M., Yeo A.E., Zhang J., Xia N.S. The role of heat shock protein 90 (HSP90) in Hepatitis E virus (HEV) capsid trafficking. J. Gen. Virol. 2010, 91:1728-1736.
199. Zou G., Puig-Basagoiti F., Zhang B., Qing M., Chen L., Pankiewicz K.W., Felczak K., Yuan Z., Shi P.Y. A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor. Virology 2009, 384:242-252.
200. Zybert I.A., van der Ende-Metselaa H., Wilschut J., Smit J.M. Functional importance of dengue virus maturation: infectious properties of immature virions. J. Gen. Virol. 2008, 89:3047-3051.