Comparative proteomic analysis of human oral fluids according to gender and age

Oral Diseases

Volumn 16, Issue 8, 2010, Pages 831-838

  Fleissig, Y ^a   Reichenberg, E ^a   Redlich, M ^b   Zaks, B ^a   Deutsch, O ^a   Aframian, D J ^b   Palmon, A ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

2 DE; Aging; ESI MS MS mass spectrometry; Gender; Oral fluids; Saliva proteins

Indexed keywords

CALGRANULIN B; IMMUNOGLOBULIN KAPPA CHAIN; PROLACTIN; TRANSFERRIN;

ADULT; AGING; ARTICLE; CLINICAL ARTICLE; FEMALE; FLUID INTAKE; GROUPS BY AGE; HUMAN; MALE; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; SEX DIFFERENCE;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BETA 2-MICROGLOBULIN; CALGRANULIN B; CARRIER PROTEINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; MALE; MIDDLE AGED; PROTEOME; PROTEOMICS; SALIVA; SALIVARY PROTEINS AND PEPTIDES; SEX FACTORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TRANSFERRIN; YOUNG ADULT;

EID: 77958172778     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2010.01696.x     Document Type: Article

References (38)

1. Aframian DJ, Davidowitz T, Benoliel R (2006). The distribution of oral mucosal pH values in healthy saliva secretors. Oral Dis 12: 420-423.
2. Ambatipudi KS, Lu B, Hagen FK, Melvin JE, Yates JR (2009). Quantitative analysis of age specific variation in the abundance of human female parotid salivary proteins. J Proteome Res 8: 5093-5102.
3. Amerongen AV, Veerman EC (2002). Saliva: the defender of the oral cavity. Oral Dis 8: 12-22.
4. Azevedo LR, Damante JH, Lara VS, Lauris JR (2005). Age-related changes in human sublingual glands: a post mortem study. Arch Oral Biol 50: 565-574.
5. Baum BJ (1993). Principles of saliva secretion. Ann N Y Acad Sci 694: 17-23.
6. Beeley JA, Khoo KS (1999). Salivary proteins in rheumatoid arthritis and Sjogren's syndrome: one-dimensional and two-dimensional electrophoretic studies. Electrophoresis 20: 1652-1660.
7. Bergquist J, Palmblad M, Wetterhall M, Hakansson P, Markides KE (2002). Peptide mapping of proteins in human body fluids using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Mass Spectrom Rev 21: 2-15.
8. Bigler LR, Streckfus CF, Dubinsky WP (2009). Salivary biomarkers for the detection of malignant tumors that are remote from the oral cavity. Clin Lab Med 29: 71-85.
9. Bradford MM (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
10. Castro J, Jimenez-Alonso J, Sabio JM et al (2003). Salivary and serum beta2-microglobulin and gamma-glutamyl-transferase in patients with primary Sjögren syndrome and Sjögren syndrome secondary to systemic lupus erythematosus. Clin Chim Acta 334: 225-231.
11. Denny P, Hagen FK, Hardt M et al (2008). The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res 7: 1994-2006.
12. Deutsch O, Fleissig Y, Zaks B, Krief G, Aframian DJ, Palmon A (2008). An approach to remove alpha amylase for proteomic analysis of low abundance biomarkers in human saliva. Electrophoresis 29: 4150-4157.
13. Ehrenfeld M, Abu-Shakra M, Buskila D, Shoenfeld Y (2001). The dual association between lymphoma and autoimmunity. Blood Cells Mol Dis 27: 750-756.
14. Fischer D, Ship JA (1999). Effect of age on variability of parotid salivary gland flow rates over time. Age Ageing 28: 557-561.
15. Fleissig Y, Deutsch O, Reichenberg E et al (2009). Different proteomic protein patterns in saliva of Sjögren's syndrome patients. Oral Dis 15: 61-68.
16. Ghafouri B, Tagesson C, Lindahl M (2003). Mapping of proteins in human saliva using two-dimensional gel electrophoresis and peptide mass fingerprinting. Proteomics 3: 1003-1015.
17. Guo T, Rudnick PA, Wang W, Lee CS, Devoe DL, Balgley BM (2006). Characterization of the human salivary proteome by capillary isoelectric focusing/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS. J Proteome Res 5: 1469-1478.
18. Hardt M, Thomas LR, Dixon SE et al (2005). Toward defining the human parotid gland salivary proteome and peptidome: identification and characterization using 2D SDS-PAGE, ultrafiltration, HPLC, and mass spectrometry. Biochemistry 44: 2885-2899.
19. Hassan MI, Waheed A, Yadav S, Singh TP, Ahmad F (2009). Prolactin inducible protein in cancer, fertility and immunoregulation: structure, function and its clinical implications. Cell Mol Life Sci 66: 447-459.
20. Hu S, Xie Y, Ramachandran P et al (2005). Large-Scale Identification of Human Oral Fluid Proteins by Liquid Chromatography-Mass Spectrometry. Proteomics 5: 1714-1728.
21. Huang CM (2004). Comparative proteomic analysis of human whole saliva. Arch Oral Biol 49: 951-962.
22. Kaufman E, Lamster IB (2002). The diagnostic applications of saliva - review. Crit Rev Oral Biol Med 13: 197-212.
23. Li SJ, Peng M, Li H et al (2009). Sys-BodyFluid: a systematical database for human body fluid proteome research. Nucleic Acids Res 37: D907-D912.
24. Lukacs JR, Largaespada LL (2006). Explaining sex differences in dental caries prevalence: saliva, hormones, and "life-history" etiologies. Am J Hum Biol 18: 540-555.
25. McKnight GS, Lee DC, Palmiter RD (1980). Transferrin gene expression. Regulation of mRNA transcription in chick liver by steroid hormones and iron deficiency. J Biol Chem 255: 148-153.
26. Moreira CR, Azevedo LR, Lauris JR, Taga R, Damante JH (2006). Quantitative age-related differences in human sublingual gland. Arch Oral Biol 51: 960-966.
27. Nagler RM (2004). Salivary glands and the aging process: mechanistic aspects, health-status and medicinal-efficacy monitoring. Biogerontology 5: 223-233.
28. Nagler RM, Hershkovich O (2005). Relationships between age, drugs, oral sensorial complaints and salivary profile. Arch Oral Biol 50: 7-16.
29. Pedersen AM, Bardow A, Jensen SB, Nauntofte B (2002). Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Dis 8: 117-129.
30. Srivastava A, Wang J, Zhou H, Melvin JE, Wong DT (2008). Age and gender related differences in human parotid gland gene expression. Arch Oral Biol 53: 1058-1070.
31. Streckfus CF, Dubinsky WP (2007). Proteomic analysis of saliva for cancer diagnosis. Expert Rev Proteomics 4: 329-332.
32. Tanida T, Ueta E, Tobiume A, Hamada T, Rao F, Osaki T (2001). Influence of aging on candidal growth and adhesion regulatory agents in saliva. J Oral Pathol Med 30: 328-335.
33. Tylenda CA, Ship JA, Fox PC, Baum BJ (1988). Evaluation of submandibular salivary flow rate in different age groups. J Dent Res 67: 1225-1228.
34. Vissink A, Spijkervet FK, Van Nieuw Amerongen A (1996). Aging and saliva: a review of the literature. Spec Care Dentist 16: 95-103.
35. Vissink A, Spijkervet FK, Van Nieuw Amerongen A (1997). Changes in secretion and composition of saliva with aging. Ned Tijdschr Tandheelkd 104: 186-189.
36. Vitorino R, Lobo MJ, Ferrer-Correira AJ et al (2004). Identification of human whole saliva protein components using proteomics. Proteomics 4: 1109-1115.
37. Williams WJ (1995). Hematology. McGraw-Hill: New York, pp. 375.
38. Yao Y, Berg EA, Costello CE, Troxler RF, Oppenheim FG (2003). Identification of protein components in human acquired enamel pellicle and whole saliva using novel proteomics approaches. J Biol Chem 278: 5300-5308.