Xanthine oxidase-derived reactive oxygen species mediate 4-oxo-2-nonenal-induced hepatocyte cell death

Toxicology and Applied Pharmacology

Volumn 249, Issue 2, 2010, Pages 127-131

  Sakuma, Satoru ^a   Negoro, Miki ^a   Kitamura, Takahiro ^a   Fujimoto, Yohko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

4 Hydroxy 2 nonenal; 4 Oxo 2 nonenal; Apoptosis; Cell death; Hepatocyte

Indexed keywords

4 HYDROXYNONENAL; 4 OXO 2 NONENAL; ALDEHYDE DERIVATIVE; ALLOPURINOL; DICHLORODIHYDROFLUORESCEIN; DICHLOROFLUORESCEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLUORESCENCE; LIPID PEROXIDATION; LIVER CELL; LIVER TOXICITY; NICK END LABELING; NONHUMAN; RAT;

ALDEHYDES; ANIMALS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; RATS; REACTIVE OXYGEN SPECIES; XANTHINE OXIDASE;

RATTUS;

EID: 77958154675     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.08.025     Document Type: Article

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